Jeffrey Wayne Stephens
Jeffrey Wayne Stephens
Professor of Diabetes

Institute of Life Sciences
Swansea University
United Kingdom

Education

1993   BSc (Hons) 1st class, Clinical & Biological Sciences 1993
Imperial College, University of London
1994 MB, BS (Distinction) Imperial College (St. Mary’s) University of London
1997 MRCP   (MRCP (UK)  Royal College of Physicians, London
2005   PhD Genetics
University College London, University of London
2009 FRCP  Royal College of Physicians, London
Other Advanced Life Support
Guys & St. Thomas’ Hospitals  1996 (recommended as instructor)
Southend Hospital  2004 (recommended as instructor)

 

Previous Positions

01.08.1994-31.01.1995  House Physician to Professor D. J. Johnston & Professor M. I. McCarthy
St. Mary's Hospital, London (Endocrinology & General Medicine)
01.02.1995-31.07.1995 House Surgeon to Mr. J. Lynn & Mr. P. Grace
Ealing Hospital, London (Endocrine & Vascular Surgery)
01.08.1995-31.07.1997 Medical Senior House Officer rotation
Northwick Park Hospital, Harrow
1997-2005 Specialist Registrar in Endocrinology & Diabetes
North Thames Rotation, London
01.09.1997-31.08.1998 Specialist Registrar to Dr. S. Beshyah Diabetes, Endocrinology & General Medicine Princess Alexandra Hospital, Harlow
01.09.1998-31.08.1999 Specialist Registrar to Dr. C. Baynes Diabetes, Endocrinology & General Medicine Chase Farm Hospital, Enfield  
01.09.1999-31.08.2000                   Specialist Registrar in Endocrinology & Diabetes
Professor D. J. Betteridge, Dr. G. S. Conway & Dr. S. J. Hurel University College London Hospitals
01.09.2000-30.09.2001 Specialist Registrar in Endocrinology & Diabetes
Professor P. M. G. Bouloux, Dr. M. Vanderpump & Dr S. Al-Damluji Royal Free Hospital
01.10.2001-30.09.2004                   Diabetes UK Research Fellow (Three-year fellowship)
Department of Diabetes & Endocrinology, UCL Hospitals & Centre for Cardiovascular Genetics, UCL
01.10.2004-31.06.2005     Specialist Registrar in Endocrinology & Diabetes Dr. J.A.O. Ahlquist & Dr. K. Metcalfe Southend Hospital

 

Biography

Professor Jeffrey W Stephens (BSc, MB BS, PhD, FRCP) qualified in Medicine from St. Mary’s Hospital Medical School (Imperial College), London in 1994. He undertook specialist training in Diabetes, Endocrinology and General Internal Medicine throughout Central London. Between 2001-2004 he undertook a PhD in Genetics based at the Centre for Cardiovascular Genetics within the School of Medicine at University College London. This was supported by a Diabetes UK Clinical Training Fellowship. He returned to Wales in 2005 to take up the post of Senior Clinical Lecturer and subsequently Reader in the College of Medicine at Swansea University. He is currently a full Professor of Medicine (Diabetes & Metabolism) based at the Institute of Life Sciences at Swansea University and a Consultant Physician in Diabetes, Endocrinology and General Internal Medicine at Morriston Hospital, Swansea. He is actively involved in both teaching and research and continues as a practicing physician in diabetes, endocrinology and general medicine. Current research interests include type 2 diabetes, obesity, cardiovascular disease and exercise in patients with type 1 diabetes. He is also actively involved in phase 2 and 3 international pharmacological clinical trials. He has >90 peer reviewed publications. He is also a member of the Council of Healthcare Professionals at Diabetes UK. He has extensive teaching experience at medical undergraduate and postgraduate level and also with allied medical specialities. He has previously held positions as Associate Dean for Academic Careers Support within the Wales Deanery, Royal College of Physicians Tutor and Postgraduate Organiser for Morriston Hospital, Swansea.

 

Research Interest

  • Clinical and basic science of type 2 diabetes
  • Obesity and cardiovascular disease
  • Clinical trials
  • Bariatric medicine and surgery
  • Exercise and diabetes

 

Professional Activities:

Research Grants

  • JW Stephens, J Halcox, SD Luzio, SC Bain. The effects of add-on treatment with Dapagliflozin on endothelial function in participants treated with GLP-1 analogues and suboptimal glycaemic control (Astra Zeneca, £135,736), 2016-).
  • NISCHR Equipment grant (ABMU Health Board). (£5507, 2015).
  • SL Prior, JS Davies, JW Stephens, Ghrelin mediated lipid retention and insulin resistance in human visceral adipose tissue. Welsh Assembly Government Studentship (NISCHR). (£66,000, 01/10/2014 - 30/09/2017).
  • JW Stephens, RM Bracken. A pilot study to evaluate the effect of a liver shrinkage diet on liver volume and metabolic function. Pathway to Portfolio grant. ABMU Health Board. (£7200, 2014).
  • KESS MSc studentship (Dafydd Hughes). 2014-2015, £19,000.
  •  Co-applicant. Lead S Bain. NISCHR Diabetes Research Unit, Cymru, (£1.5 million, 5 years 2015-).
  • JW Stephens, RM Bracken, S Mallalieu. Workplace based risk identification and health promotion for cardiovascular disease and Type 2 diabetes. A comparative feasibility study in three workplace settings (KESS PhD studentship, £60000, 3 years, 2011).
  • JW Stephens, S Rice. A worksite delivered health screening and intervention programme/ analysis of unidentified disease prevalence and relative effectiveness in working age, populations in South West Wales (NISCHR AHSC Clinical Research Time Competition 2011/12 for Dr Sam Rice, 3 years, $162034, 2012).
  • JW Stephens, S.L. Prior. Adipose tissue as a mediator of inflammation and oxidative cellular damage in obesity and type 2 diabetes (WAG PhD studentship for D Jones, £60000, 3 years, 2009).
  • R Thomas, T Gorvett, JW Stephens, S Allen, O Jameh, O Nyan. Professional Nurse Development Programme in Diabetes Care (Aelsh Assembly Government, £9370, 2009-2010).
  • RM Bracken. JW Stephens, SC Bain, P Foley. Identification of breath biomarkers of oxidative stress in people with diabetes: relationships to established blood markers and effects of alterations in diet and exercise (WAG PhD studentship for R Mortan, £68290, 3 years, 2009).
  • RM Bracken, JW Stephens, SC Bain. Factors pertaining to the occurrence of late-onset hypoglycaemia in the exercising Type 1 diabetes patient (WAG PhD studentship for D West, £64000, 3 years, 2008).
  • S Brophy, H Davies, S Bain, JW Stephens, I Russell, R Williams. Randomized, controlled, parallel-group study to investigate the clinical effectiveness of early insulin treatment in patients with latent autoimmune diabetes in adults (LADA) (Novonordisk £498000, 3 years, 2008).
  • JW Stephens, R Williams, J Baxter, SC Bain.  Incretin hormones, obesity & impaired glucose homeostasis: Bariatric surgery as a tool to study the role of incretin hormones in obesity and associated metabolic dysfunction (BUPA Medical Foundation, £96163, 3 years, 2007).
  • JW Stephens, SC Bain. A study to examine the influence of repaglinide on the ‘incretin effect’ and oxidative damage associated with postprandial hyperglycaemia (Novonordisk £100000, 2 years, 2007).
  • R Bracken, M Kingsley, JW Stephens, SC Bain. A pilot study to compare the metabolic, glucoregulatory hormone and cardiorespiratory responses to exercise in Type 1 diabetic patients (Diabetes UK £47902, 2007).
  • JW Stephens, J Baxter. A pilot study to look at the early and late temporal changes in cardiac function following bariatric surgery in obese subjects (Swansea NHS £3520, 1 year, 2007).
  • JW Stephens, M Williams, R Williams, S Bain. A pilot study to examine available guidelines for the follow-up of groups at high-risk for type 2 diabetes mellitus (GSK, Takeda, £30000, 2 years, 2008; Merck £10000, 2010 1 year).
  • JW Stephens, J Nedin. A pilot study examining group and 1:1 education for obesity in the Primary and Secondary Care Settings (Sanofi Aventis, £29770, 2008-2009).

 

 

Publications

Original Research

  1. Gray BJ, Bracken RM, Turner D, Morgan K, Thomas M, Williams SP, Williams M, Rice S, Stephens JW; Prosiect Sir Gâr Group. Different type 2 diabetes risk assessments predict dissimilar numbers at 'high risk': a retrospective analysis of diabetes risk-assessment tools. Br J Gen Pract. 2015 Dec;65(641):e852-60.
  2. Handley JD, Baruah BP, Williams DM, Horner M, Barry J, Stephens JW. Bariatric surgery as a treatment for idiopathic intracranial hypertension: a systematic review. Surg Obes Relat Dis. 2015 Nov-Dec;11(6):1396-403.
  3. Mallipedhi A, Min T, Prior SL, MacIver C, Luzio SD, Dunseath G, Bracken RM, Islam S, Barry JD, Caplin S, Stephens JW. Association between the preoperative fasting and postprandial C-peptide AUC with resolution of type 2 diabetes 6 months following bariatric surgery. Metabolism. 2015 Nov;64(11):1556-63.
  4. Gray BJ, Stephens JW, Williams SP, Davies CA, Turner D, Bracken RM; Prosiect Sir Gâr Group. Cardiorespiratory fitness is a stronger indicator of cardiometabolic risk factors and risk prediction than self-reported physical activity levels. Diab Vasc Dis Res. 2015 Nov;12(6):428-35.
  5. Gray BJ, Page R, Turner D, West D, Campbell MD, Kilduff LP, Stephens JW, Bain SC, Bracken RM. Improved end-stage high intensity performance but similar glycaemic responses after waxy barley starch ingestion compared to dextrose in type 1 diabetes. J Sports Med Phys Fitness. 2015 Jul 29. [Epub ahead of print].
  6. Mallipedhi A, Prior SL, Dunseath G, Bracken RM, Barry J, Caplin S, Morgan S, Baxter JN, O’Sullivan SE, Sarmad S, Barrett DA, Bain SC, Luzio SD, Stephens JW. Changes in plasma levels of N-arachidonyl ethanolamine and N-palmitoyl ethanolamine following bariatric surgery in morbidly obese females with impaired glucose homeostasis. J Diabetes Res. 2015;2015:680867..
  7. Radwan R, Al-Momani H, Eyre N, Stephens JW, Caplin S, Barry JD. Bariatric surgery is associated with a significant reduction in 10-year cardiovascular risk. Bariatric Surgical Practice and Patient Care. 2015;10(1):30-32.
  8. Jones DA, Prior SL, Barry JD, Caplin S, Baxter JN, Stephens JW. Changes in markers of oxidative stress and DNA damage in human visceral adipose tissue from subjects with obesity and type 2 diabetes. Diabetes Res Clin Pract. 2014 Dec;106(3):627-33.
  9. Mallipedhi A, Prior SL, Barry JD, Caplin S, Baxter JN, Stephens JW. Changes in inflammatory markers after sleeve gastrectomy in patients with impaired glucose homeostasis and type 2 diabetes. Surg Obes Relat Dis. 2014 Nov-Dec;10(6):1123-8.
  10. Gray BJ, Bracken RM, Thomas M, Williams SP, Williams M, Rice S, Stephens JW; Prosiect Sir Gâr Group.  'Prosiect Sir Gâr': workplace-based cardiovascular disease and diabetes risk assessments.  Occup Med (Lond). 2014 Oct;64(7):549-56.
  11. Gray BJ, Bracken RM, Turner D, Morgan K, Mellalieu SD, Thomas M, Williams SP, Williams M, Rice S, Stephens JW; Prosiect Sir Gâr Group. Predicted 10-year risk of cardiovascular disease is influenced by the risk equation adopted: a cross-sectional analysis. Br J Gen Pract. 2014 Oct;64(627):e634-40.
  12. Zain M Fazli RA, Cooper JA, Li KW, Palmen J, Acharya J, Howard P, Shahid M, Baig SM, Elkeles RS, Stephens JW, Ireland H, Humphries SE. Association of TLL1 Gene Polymorphism (rs1503298, T > C) with Coronary Heart Disease in PREDICT, UDACS and ED Cohorts. Journal of the College of Physicians and Surgeons Pakistan 2014 Sep;24(9):615-9.
  13. Mallipedhi A, Prior SL, Barry JD, Caplin S, Baxter JN, Stephens JW. Temporal changes in glucose homeostasis and incretin hormone response at 1 and 6 months after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis. 2014 Sep-Oct;10(5):860-9.
  14. Gray BJ, Bracken RM, Turner D, Morgan K, Mellalieu SD, Thomas M, Williams SP, Williams M, Rice S, Stephens JW. Prevalence of undiagnosed cardiovascular risk factors and 10-year CVD risk in male steel industry workers. J Occup Environ Med. 2014 May;56(5):535-9.
  15. Maubaret CG, Salpea KD, Romanoski CE, Folkersen L, Cooper JA, Stephanou C, Li KW, Palmen J, Hamsten A, Neil A, Stephens JW, Lusis AJ, Eriksson P, Talmud PJ, Humphries SE; Simon Broome Research Group; EARSII consortium. Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease. PLoS One. 2013 Dec 12;8(12):e83122. doi: 10.1371/journal.pone.0083122. eCollection 2013.
  16. Thomas RL, Prior SL, Barry JD, Luzio SD, Eyre N, Caplin S, Stephens JW, Owens DR. Does bariatric surgery adversely impact on diabetic retinopathy in persons with morbid obesity and type 2 diabetes? A pilot study. J Diabetes Complications. 2014 Mar-Apr;28(2):191-5.
  17. Campbell MD, West DJ, Bain SC, Kingsley MI, Foley P, Kilduff L, Turner D, Gray B, Stephens JW, Bracken RM. Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients. Scand J Med Sci Sports. 2014 Mar 4. doi: 10.1111/sms.12192. [Epub ahead of print].
  18. Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EP, Li M, Leusink M, Trompet S, Verschuren JJ, Hovingh GK, Dehghan A, Nelson CP, Kotti S, Danchin N, Scholz M, Haase CL, Rothenbacher D, Swerdlow DI, Kuchenbaecker KB, Staines-Urias E, Goel A, Hooft FV, Gertow K, de Faire U, Panayiotou AG, Tremoli E, Baldassarre D, Veglia F, Holdt LM, Beutner F, Gansevoort RT, Navis GJ, Leach IM, Breitling LP, Brenner H, Dallmeier D, Franco-Cereceda A, Boer J, Stephens JW, et al. Secretory Phospholipase A2-IIA and Cardiovascular Disease: a Mendelian randomization study.  J Am Coll Cardiol. 2013 Jul 19. pii: S0735-1097(13)02778-2. doi: 10.1016/j.jacc.2013.06.044. [Epub ahead of print].
  19. Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium, Hingorani AD, Casas JP. The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012 Mar 31;379(9822):1214-24.
  20. Prior SL, Clark AR, Jones DA, Bain SC, Hurel SJ, Humphries SE, Stephens JW. Association of the PGC-1α rs8192678 variant with microalbuminuria in subjects with type 2 diabetes mellitus. Dis Markers. 2012 Jan 1;32(6):363-9.
  21. Alam I, Stephens JW, Fielding A, Lewis KE, Lewis MJ, Baxter JN. Temporal changes in glucose and insulin homeostasis after biliopancreatic diversion and laparoscopic adjustable gastric banding. Surg Obes Relat Dis. 2011 Nov-Dec;8(6):752-63.
  22. Bracken RM, Page R, Gray B, Kilduff LP, West DJ, Stephens JW, Bain SC. Isomaltulose improves glycemia and maintains run performance in type 1 diabetes. Med Sci Sports Exerc. 2012 May;44(5):800-8.
  23. Ghosal S, Stephens J, Mukherjee A. Quantitative vibration perception threshold in assessing diabetic neuropathy: is the cut-off value lower for Indian subjects? [Q-VADIS Study]. Diabetes Metab Syndr. 2012 Apr-Jun;6(2):85-9.
  24. Yiannakouris N, Cooper JA, Shah S, Drenos F, Ireland HA, Stephens JW, Li KW, Elkeles R, Godsland IF, Kivimaki M, Hingorani AD, Kumari M, Talmud PJ, Humphries SE. IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk. Nutr Metab Cardiovasc Dis. 2012 Dec;22(12):1024-30.
  25. Stephens JW, Bodvarsdottir TB, Wareham K, Prior SL, Bracken RM, Lowe GD, Rumley A, Dunseath G, Luzio S, Deacon CF, Holst JJ, Bain SC. Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in subjects with type 2 diabetes mellitus. Diabetes Res Clin Pract. 2011 Nov;94(2):199-206.
  26. Brophy S, Davies H, Dunseath G, Stephens JW, Platts J, Lane H, Beaverstock C, Wakeman L, Russell I, Williams M, Williams DR. Experience of the introduction of routine antibody testing in primary care and of running a trial for latent autoimmune diabetes in adults (LADA). Diabetes Res Clin Pract. 2011 Jul;93(1):e49-52.
  27. Harrison SC, Cooper JA, Li K, Talmud PJ, Sofat R, Stephens JW, Hamsten A; on behalf of the HIFMECH Consortium, Sanders J, Montgomery H, Neil A; on behalf of the Simon Broome Research Consortium, Humphries SE. Association of a sequence variant in DAB2IP with coronary heart disease. Eur Heart J. 2012 Apr;33(7):881-8.
  28. Thong KY, Jose B, Sukumar N, Cull ML, Mills AP, Sathyapalan T, Shafiq W, Rigby AS, Walton C, Ryder RE; ABCD Nationwide Exenatide Audit Contributors..Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit. Diabetes Obes Metab. 2011 Aug;13(8):703-10.
  29. Bracken RM, West DJ, Stephens JW, Kilduff LP, Luzio S, Bain SC. Impact of pre-exercise rapid-acting insulin reductions on ketogenesis following running in Type 1 diabetes. Diabet Med. 2011 Feb;28(2):218-22.
  30. Prior SL, Jones DA, Gill GV, Bain SC, Stephens JW. Association of the adiponectin rs266729 C>G variant and coronary heart disease in the low risk 'Golden Years' type 1 diabetes cohort. Diabetes Res Clin Pract. 2011 Mar;91(3):e71-4.
  31. Tang TS, Prior SL, Li KW, Ireland HA, Bain SC, Hurel SJ, Cooper JA, Humphries SE, Stephens JW. Association between the rs1050450 glutathione peroxidase-1 (C > T) gene variant and peripheral neuropathy in two independent samples of subjects with diabetes mellitus. Nutr Metab Cardiovasc Dis. 2012 May;22(5):417-25.
  32. West DJ, Stephens JW, Bain SC, Kilduff LP, Luzio S, Still R, Bracken RM..A combined insulin reduction and carbohydrate feeding strategy 30 min before running best preserves blood glucose concentration after exercise through improved fuel oxidation in type 1 diabetes mellitus. J Sports Sci. 2011 Feb;29(3):279-89.
  33. Brophy S, Davies H, Stephens JW, Prior SL, Atkinson M, Bain S, Williams R. Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study. BMC Res Notes. 2010 Nov 22;3:317.
  34. Thomas R, Brenton K, Harris B, Ham R, Rees G, Gorvett T, Boregowda K, Stephens JW, Price DE. Foot ulceration in a secondary care diabetic clinic population: a 4-year prospective study. Diabetes Res Clin Pract. 2010 Nov;90(2):e37-9.
  35. Jones DA, Prior SL, Tang TS, Bain SC, Hurel SJ, Humphries SE, Stephens JW. Association between the rs4880 superoxide dismutase 2 (C>T) gene variant and coronary heart disease in diabetes mellitus. Diabetes Res Clin Pract. 2010 Nov;90(2):196-201.
  36. West DJ, Morton RD, Stephens JW, Bain SC, Kilduff LP, Luzio S, Still R, Bracken RM. Isomaltulose Improves Postexercise Glycemia by Reducing CHO Oxidation in T1DM. Med Sci Sports Exerc. 2011 Feb;43(2):204-10.
  37. West DJ, Morton RD, Bain SC, Stephens JW, Bracken RM. Blood glucose responses to reductions in pre-exercise rapid-acting insulin for 24 h after running in individuals with type 1 diabetes.  J Sports Sci. 2010 May;28(7):781-8.
  38. Morton RD, West DJ, Stephens JW, Bain SC, Bracken RM. Heart rate prescribed walking training improves cardiorespiratory fitness but not glycaemic control in people with type 2 diabetes. J Sports Sci. 2010 Jan;28(1):93-9.
  39. Natarajan B, Edavalath M, Davies J, Jenkins L, Marshall-Richards N, Evans D, Price DE, Bain SC, Stephens JW. Clinical experience with exenatide in a routine secondary care diabetes clinic. Prim Care Diabetes. 2010 Apr;4(1):57-60.
  40. Salpea KD, Talmud PJ, Cooper JA, Maubaret CG, Stephens JW, Abelak K, Humphries SE. Association of telomere length with type 2 diabetes, oxidative stress and UCP2 gene variation. Atherosclerosis. 2010 Mar;209(1):42-50.
  41. Alam I, Lewis MJ, Lewis KE, Stephens JW, Baxter JN. Influence of bariatric surgery on indices of cardiac autonomic control. Auton Neurosci. 2009 Dec 3;151(2):168-73.
  42. Brooks CJ, Stephens JW, Price DE, Ford DV, Lyons RA, Prior SL, Bain SC. Use of a patient linked data warehouse to facilitate diabetes trial recruitment from primary care. Prim Care Diabetes. 2009 Nov;3(4):245-8.
  43. Prior SL, Bain SC, Stephens JW, Alam I, Baxter JN. Total antioxidant status before and after bariatric surgery for type 2 diabetes mellitus. Metabolism. 2009;58(9):1366.
  44. Brooks CJ, Tang TS, Ford DV, Lyons RA, Price DE, Bain SC, Stephens JW. Are blood pressure levels taken during a secondary care diabetic clinic likely to be higher than when measured in primary care? Prim Care Diabetes. 2009 Aug;3(3):193-5.
  45. Prior SL, Gable DR, Cooper JA, Bain SC, Hurel SJ, Humphries SE, Stephens JW. Association between the adiponectin promoter rs266729 gene variant and oxidative stress in patients with diabetes mellitus. Eur Heart J. 2009;30(10):1263-9.
  46. Prior SL, Javid J, Gill GV, Bain SC, Stephens JW. The adiponectin rs17300539 G>A variant and nephropathy risk. Kidney Int. 2008;74(10):1361.
  47. Huth C, Illig T, Herder C, Gieger C, Grallert H, Vollmert C, Rathmann W, Hamid YH, Pedersen O, Hansen T, Thorand B, Meisinger C, Doring A, Klopp N, Gohlke H, Lieb W, Hengstenberg C, Lyssenko V, Groop L, Ireland H, Stephens JW et al. Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index. Ann Med 2008; 27:1-21
  48. Salpea KD, Gable DR, Cooper JA, Stephens JW, Hurel SJ, Ireland HA, Feher MD, Godsland IF, Humphries SE. The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects. Nutr Metab Cardiovasc Dis. 2008;18(1):7-14.
  49. Brophy S, Davies H, Bain S, Stephens JW, Cheung WY, Richards K, Wareham K, Beaverstock C, Lloyd J, Page D, Williams M, Russell I et al. Randomized, controlled, parallel-group prospective study to investigate the clinical effectiveness of early insulin treatment in patients with latent autoimmune diabetes in adults. BMC Endocr Disord. 2008: 24;8:8.
  50. Thompson SR, Sanders J, Stephens JW, Miller GJ, Humphries SE. A common interleukin 18 haplotype is associated with higher body mass index in subjects with diabetes and coronary heart disease. Metabolism. 2007;56(5):662-9.
  51. Muthumala A, Gable DR, Palmen J, Cooper JA, Stephens JW, Miller GJ, Humphries SE.  Is the influence of variation in the ACE gene on the prospective risk of type 2 diabetes in middle aged men modified by obesity? Clin Sci (Lond). 2007; 113(12):467-72.
  52. Wootton PT, Arora NL, Drenos F, Thompson SR, Cooper JA, Stephens JW, Hurel SJ, Hurt-Camejo E, Wiklund O, Humphries SE, Talmud PJ. Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study. Hum Mol Genet. 2007;16(12):1437-44.
  53. Stephens JW, Dhamrait SS, Mani AR, Acharya J, Moore K, Hurel SJ, Humphries SE. Interaction between the uncoupling protein 2 -866G>A gene variant and cigarette smoking to increase oxidative stress in subjects with diabetes. Nutr Metab Cardiovasc Dis. 2008;18:7-14.
  54. Gable DR, Stephens JW, Dhamrait SS, Hawe E, Humphries SE; Hifmech Study Group.  European differences in the association between the UCP2 -866G > A common gene variant and markers of body mass and fasting plasma insulin. Diabetes Obes Metab. 2007;9(1):130-1.
  55.  Dorfmeister B, Cooper JA, Stephens JW, Ireland H, Hurel SJ, Humphries SE, Talmud PJ.  The effect of APOA5 and APOC3 variants on lipid parameters in European Whites, Indian Asians and Afro-Caribbeans with type 2 diabetes. Biochim Biophys Acta. 2007;1772:355-63.
  56. Stephens JW, Hurel SJ, Lowe GD, Rumley A, Humphries SE. Association between plasma IL-6, the IL6 -174G>C gene variant and the metabolic syndrome in type 2 diabetes mellitus. Mol Genet Metab. 2007;90(4):422-8.
  57. Humphries SE, Gable D, Cooper JA, Ireland H, Stephens JW, Hurel SJ, Li KW, Palmen J, Miller MA, Cappuccio FP, Elkeles R, Godsland I, Miller GJ, Talmud PJ. Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women. J Mol Med. 2006;84(12):1-10.
  58. Huth C, Heid IM, Vollmert C, Gieger C, Grallert H, Wolford JK, Langer B, Thorand B, Klopp N, Hamid YH, Pedersen O, Hansen T, Lyssenko V, Groop L, Meisinger C, Doring A, Lowel H, Lieb W, Hengstenberg C, Rathmann W, Martin S, Stephens JW, et al. IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies. Diabetes 2006;55(10):2915-21.
  59. Stephens JW, Dhamrait SS, Acharya J, Humphries SE, Hurel SJ. A common variant in the ACE gene is associated with peripheral neuropathy in women with type 2 diabetes mellitus. J Diabetes Complications. 2006;20(5):317-21.
  60. Shamaei-Tousi A, Steptoe A, O'Donnell K, Palmen J, Stephens JW, Hurel SJ, Marmot M, Homer K, D'Aiuto F, Coates AR, Humphries SE, Henderson B. Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors. Cell Stress Chaperones. 2007;12(4):384-92.
  61. Shamaei-Tousi A, Stephens JW, Bin R, Cooper JA, Steptoe A, Coates AR, Henderson B, Humphries SE. Association between plasma levels of heat shock protein 60 and cardiovascular disease in patients with diabetes mellitus. Eur Heart J. 2006;27(13):1565-70.
  62. Casas JP, Shah T, Cooper J, Hawe E, McMahon AD, Gaffney D, Packard CJ, O'Reilly DS, Juhan-Vague I, Yudkin JS, Tremoli E, Margaglione M, Di Minno G, Hamsten A, Kooistra T, Stephens JW, Hurel SJ, Livingstone S, Colhoun HM, Miller GJ, Bautista LE, Meade T, Sattar N, Humphries SE, Hingorani AD. Insight into the nature of the CRP-coronary event association using Mendelian randomization. Int J Epidemiol. 2006;35(4):922-31.
  63. Wootton PT, Stephens JW, Hurel SJ, Durand H, Cooper J, Ninio E, Humphries SE, Talmud PJ. Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus. Atherosclerosis 2006;189(1):149-56.
  64. Gable DR, Stephens JW, Cooper JA, Miller GA, Humphries SE. Variation in the UCP2-UCP3 Gene Cluster Predicts the Development of Type 2 Diabetes in Healthy Middle-Aged Men. Diabetes. 2006;55(5):1504-11.
  65. Wootton PT, Drenos F, Cooper JA, Thompson SR, Stephens JW, Hurt-Camejo E, Wiklund O, Humphries SE, Talmud PJ. Tagging-SNP haplotype analysis of the secretory PLA2IIa gene PLA2G2A shows strong association with serum levels of sPLA2IIa: results from the UDACS study. Hum Mol Genet. 2006;15(2):355-61.
  66. Stephens JW, Gable DR, Hurel SJ, Miller GJ, Cooper JA, Humphries SE. Increased plasma markers of oxidative stress are associated with coronary heart disease in males with diabetes mellitus and with 10-year risk in a prospective sample of males. Clin Chem. 2006;52:446-52.
  67. Stephens JW, Dhamrait SS, Acharya J, Humphries SE, Hurel SJ. A common variant in the ACE gene is associated with peripheral neuropathy in women with Type 2 Diabetes Mellitus. J Diab and its Compl, 2006;20(5):317-21.
  68. Talmud PJ, Stephens JW, Hawe E, Hurel SJ, Humphries SE, Ordovas JM. The significant increase in cardiovascular disease risk in APOEepsilon4 carriers is evident only in men who smoke: potential relationship between reduced antioxidant status and ApoE4. Annals of Human Genetics 2005; 69(Pt 6):613-22..
  69. Hayek T; Stephens JW, Hubbart CS, Acharya J, Caslake M, Hawe E, Miller GJ, Hurel SJ, Humphries SE.  A common variant in the Glutathione S Transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus. Atherosclerosis 2006; 184: 404-412.
  70. Stephens JW, Dhamrait SS, Cooper JA, Acharya J, Miller GJ, Hurel SJ, Humphries SE. The D allele of the ACE I/D common gene variant is associated with Type 2 diabetes mellitus in Caucasian subjects. Molecular Genetics & Metabolism 2005; 84: 83-89.
  71. Flavell DM, Ireland H, Stephens JW, Hawe E, Hurel SJ, Humphries SE. PPARa gene variation influences age of onset & progression of type 2 diabetes. Diabetes 2005; 54: 582-586.
  72. Stephens JW, Ambler G, Vallance P, Betteridge DJ, Humphries SE, Hurel SJ. Cardiovascular  risk & diabetes. Are the methods of risk prediction satisfactory? European Journal of Cardiovascular Prevention & Rehabilitation 2004; 11(6):521-528.
  73. Stephens JW, Sozen MM,  Whittall RA, Caslake M, Acharya J, Hurel SJ, Humphries SE. Three novel mutations in the Apolipoprotein E gene in a sample of subjects with Type 2 diabetes mellitus. Clin Chem. 2005;51(1):119-24.
  74. Clapp BR, Hingorani AD, Kharbanda RK, Mohamed-Ali V, Stephens JW, Vallance P, MacAllister RJ. Inflammation induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. Cardiovasc Res 2004; 64: 172-178.
  75. Stephens JW; Wong WR, Acharya J, Hurel SJ, Humphries SE, Talmud PJ. The ApoA4 T347S is associated with reduced plasma total antioxidant status in subjects with diabetes mellitus and cardiovascular disease. J Lipid Res 2004; 45: 1565-1571.
  76. Stephens JW, Humphries SE, Cooper JA, Hurel SJ. What are the Clinical Manifestations of Cardiovascular Disease in Diabetes? Ten year analysis from a clinic based population. Br J Diabetes Vasc Dis 2004; 4: 190-194.
  77. Stephens JW, Hurel SJ, Cooper JA, Acharya J, Miller GJ, Humphries SE. A common functional variant in the interleukin-6 gene is associated with increased body mass index in subjects with type 2 diabetes mellitus. Molecular Genetics & Metabolism 2004; 82: 180-186.
  78. Stephens JW, Hurel SJ, Acharya J,Humphries SE. An interaction between the interleukin-6    -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes. Cardiovasc Diabetol. 2004; 3(1): 2.
  79. Stephens JW; Dhamrait SS, Cooper JA, Acharya J, Miller GJ, Mani AR, Moore K, Humphries SE, Hurel SJ, Montgomery HE. Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2. Eur Heart J. 2004; 25(6): 468-75.
  80. Stephens JW, Palmen JM, Hurel SJ, Humphries SE. A long-range PCR method for genotyping promoter variants in the interleukin-6 gene. Thrombosis and Haemostasis 2003; 89: 765-767.
  81. Stephens JW, Butteriss D, Payne N, Barker SGE, Hurel SJ. Subcutaneous insulin without a needle: a pilot evaluation of the J-Tip delivery system. Practical Diabetes International 2003; 20(2): 47-50.
  82. Schofield JN, Stephens JW, Hurel SJ, Bell KM, deSouza JB, Rademacher TW. Insulin reduces serum glycosylphosphatidylinositol phospholipase d levels in human type I diabetic patients and streptozotocin diabetic rats. Molecular Genetics & Metabolism 2002; 75: 154-61.
  83. Maher D, Mvula B, Stephens J, Hamandi K. Transport and referral of medical inpatients in Blantyre, Malawi. Tropical Disease 1995; 25(2):93.

Case Reports/ letters

  1. Rees DO, Anthony VA, Jones K, Stephens JW. Follicular variant of papillary thyroid carcinoma: an unusual cause of thyrotoxicosis. BMJ Case Rep. 2015 May 6;2015. pii: bcr2014207091. doi: 10.1136/bcr-2014-207091.
  2. Min T, Handley J, Williams D, Price DE, Stephens JW. Renal function and dapagliflozin in routine clinical practice. J Diabetes. 2015 Mar 26. doi: 10.1111/1753-0407.12291. [Epub ahead of print].
  3. Lomova-Williams L, Mallipedhi A, MacIver C, Price DE, Thomas R, Ferguson C, Stephens JW. Research letter in relation to paper by Bongaerts et al., a clinical screening score for diabetic polyneuropathy: KORA F4 and AusDiab studies. J Diabetes Complications. 2015 Mar;29(2):318-9.
  4. Pitrola D, MacIver C, Mallipedhi A, Udiawar M, Price DE, Stephens JW. Cutaneous allergy to insulin: could statins and ACE inhibitors play a role? A case report. Diabetes Res Clin Pract. 2014 Apr;104(1):e20-2.
  5. Wilson V, Mallipedhi A, Stephens JW, Redfern RM, Price DE.  The causes of hypopituitarism in the absence of abnormal pituitary imaging. QJM. 2013 Oct 17. [Epub ahead of print].
  6. Anthony VA, Rees DO, Stephens JW. Isolated B-cell non-Hodgkin's lymphoma of the parotid gland presenting as an ulcerating facial mass and sepsis during an acute medical take. BMJ Case Rep. 2013 Jan 25;2013.
  7. Rees DO, Price DE, Bain SC, Stephens JW. Response to Nandakoban et al. Acute tubulointerstitial nephritis following treatment with exenatide. Diabet Med. 2013 Feb;30(2):251-2.
  8.  Palmer F, Prior SL, Mallipedhi A, Jones DA, Price DE, Stephens JW. Treatment choices for managing hyperglycaemia in patients with type 2 diabetes and moderate to severe renal disease. Diabetes Res Clin Pract. 2012 Aug;97(2):e23-4.
  9. Stephens JW, Boregowda K, Barry J, Price DE, Eyre N, Baxter JN. Adrenal insufficiency following bariatric surgery. Obes Rev. 2012 Jun;13(6):560-2.
  10. Abu-Roomi SR, Mallipedhi A, Bain SC, Price DE, Stephens JW. Quality and Outcomes Framework screening questions for depression in patients with diabetes: effective but non-efficient. Diabet Med. 2012 Jul;29(7):957-8.
  11. Prior SL, Stephens JW. Relationship between proteolytic enzyme activity and oxidative stress in subjects with diabetes. International Journal of Endocrinology & Metabolism 2011; 8(4): 218-219.
  12. Boregowda K, Joels L, Stephens JW, Price DE. Persistent primary hypogonadism associated with anabolic steroid abuse. Fertil Steril. 2011 Jul;96(1):e7-8.
  13. Stephens JW, Carman JE, Brooks CJ, Lyons RA, Ford DV, Price DE, Bain SC. Structured self-monitoring of blood glucose significantly reduces A1C levels in poorly controlled, noninsulin-treated type 2 diabetes: results from the structured testing program study. Diabetes Care 2011;34:262-267.
  14. Stephens JW, Carman JE, Prior SL, Jones DA, Price DE. Glycaemic control and other cardiovascular risk factors should be targeted independently in patients with type 2 diabetes mellitus. Atherosclerosis. 2011 Jul;217(1):297-8.
  15. Bracken RM, Edavalath M, Morton R, West D, Fielding A, Luzio S, Underwood P, Stephens JW. Exercise-induced hyperglycaemia in the absence of diabetes. Diabet Med. 2010 Jun;27(6):723-4.
  16. Haboubi H, Azam I, Edavalath M, Redfern RM, Price DE, Stephens JW. Apoplexy in a corticotrphin-secreting pituitary macroadenoma: a case report and review of the literature. QJM. 2010 Aug;103(8):607-9.
  17. de Lacy P, Benjamin S, Dixon R, Stephens JW, Redfern R, Price DE. Is surgical intervention frequently required for medically managed macroprolactinomas? A study of spontaneous cerebrospinal fluid rhinorrhea. Surg Neurol. 2009 Nov;72(5):461-3.
  18. Natarajan B, Stephens JW. Haemorrhagic cardiac tamponade: a rare complication of pneumonia. QJM. 2009 Nov;102(11):813-4.
  19. Hancock S, Still RA, Fielding AM, Doran JF, Stephens JW. A rare cause of Cushing's syndrome demonstrates analytical discrepancies between the Roche E170 and Bayer Centaur testosterone assays. Ann Clin Biochem. 2008 May;45(Pt 3):328-30.
  20. Stephens JW, Williams R. Authors' response. Diabet Med. 2007 24(8):924-5. 
  21. Stephens JW, Fielding A, Verdaguer R, Freites O. A steroid-cell tumor of the ovary resulting in massive androgen excess early in the gonadol steroidogenic pathway. Gynecol Endocrinol. 2008;24(3):151-3.
  22. Rao A, Iqbal M, Price DE, Stephens JW. Necrotizing fasciitis and hypothyroidism. QJM. 2007;100(8):533-4.
  23. Stephens JW, Price DE, Ionescu A. Dopamine agonists and valvular heart disease. N Engl J Med. 2007 Apr 19;356(16):1676; author reply 1678-80.
  24. McCarthy D, Patel C, Ahlquist JA, Stephens JW. Unilateral ocular myasthenia gravis in an acute medical take: is a Tensilon test useful? Br J Hosp Med (Lond). 2006;67(4):210.
  25. Silviera L, Stephens J, Bouloux P. Non-islet cell tumour hypoglycaemia : a case report and review of the literature. CME Endocrinology & Diabetes 2003; 4: 67-72.              
  26. Stephens JW, Katz JR, McDermott N, MacLean AB, Bouloux PM-G. A gonadotrophin-driven, steroid producing ovarian tumour: a rare cause of post-menopausal hirsutism. Human Reproduction 2002; 17: 1468-1471.
  27. Stephens JW, Morganstein DL, McLaughlin JE, Dorwood N, Vanderpump MP. Isolated B-cell lymphoma of the pituitary region: a rare clinical entity. Hospital Medicine 2002; 63: 306-307.
  28. Ames PRJ, Stephens JW, Steuer A, Gumpel JM. Prolonged healing of malleolar ulcers after fibrinolytic treatment in a woman with systemic sclerosis. British Journal of Rheumatology 1997; 37(1):107.

Reviews

  1. Min T, Stephens JW. Targeting abdominal obesity in diabetes. Diabetes Management. 2015; 5(4):301-309.
  2. Williams DM, Stephens JW. Combination therapy with saxagliptin and dapagliflozin for the treatment of type 2 diabetes. Expert Opin Pharmacother. 2015;16(15):2373-9.
  3. Stephens J, Kempf, Heinemann L, Martin S. Debate: Self monitoring of blood glucose by people with type 2 diabetes. Diabetes Voice. 2014; 59(2):47-51.
  4. Williams R, Stephens J. SGLT2 inhibitors-A useful addition to therapy? Diabetes Voice. 2013;58(1):33-35
  5. King EJ, Haboubi H, Evans D, Baker I, Bain SC, Stephens JW. The management of diabetes in terminal illness related to cancer. QJM. 2012 Jan;105(1):3-9.
  6. Stephens JW. The incretin system in the management of type 2 diabetes mellitus. Clin Med. 2010 Oct;10(5):491-5.
  7. Edavalath M, Stephens JW. Liraglutide in the treatment of type 2 diabetes mellitus: clinical utility and patient perspectives. Patient Prefer Adherence. 2010 Mar 24;4:61-8.
  8. Davies H, Brophy S, Bain SC, Stephens JW, Lewis J, Luzio S, Dunseath G, Beaverstock C, Williams DR. GADA testing: the current state of knowledge. Prim Care Diabetes. 2009 Aug;3(3):189-91.
  9. Stephens JW, Khanolkar MP, Bain SC. The biological relevance and measurement of plasma markers of oxidative stress in diabetes and cardiovascular disease. Atherosclerosis 2009; 202(2):321-9.
  10. Stephens JW, Bain SC, Humphries SE. Gene-environment interaction and oxidative stress in cardiovascular disease. Atherosclerosis 2008 Oct;200(2):229-38.
  11. Khanolkar MP, Bain SC, Stephens JW. The diabetic foot. QJM. 2008;101(9):685-95.
  12. Khanolkar MP, Bain SC, Stephens JW. Assessing and treating the diabetic foot. MIMS dermatology 2007; 3(4); 23-26.
  13. Stephens JW, Bain SC. Safety and adverse effects associated with GLP-1 analogues. Expert Opin Drug Saf. 2007;6(4):417-22.
  14. Alam I, Lewis K, Stephens JW, Baxter JN. Obesity, metabolic syndrome and sleep apnoea: all pro-inflammatory states. Obes Rev. 2007 Mar;8(2):119-27.
  15. Talmud PJ & Stephens JW. Lipoprotein gene variants and the effect of environmental factors on cardiovascular disease risk. Diabetes, Obesity and Metabolism 2004; 6: 1-7.
  16. Stephens JW & Humphries SE. The Molecular Genetics of Cardiovascular Disease: Clinical Implications. Journal of Internal Medicine 2003; 253:120-127.
  17. Stephens JW, Baynes C, Hurel SJ. Amiodarone & Thyroid dysfunction: A case illustrated guide to management. British Journal of Cardiology 2001; 8: 499-506.

Editorials

  1. Kalea AZ, Harrison SC, Stephens JW, Talmud PJ. Genetic susceptibility for coronary heart disease and type 2 diabetes complications. Clin Chem. 2012 May;58(5):818-20.
  2. Davies H, Brophy S, Bain SC, Stephens JW, Lewis J, Luzio S, Dunseath G, Beaverstock C, Williams DR. GADA testing: The current state of knowledge. Prim Care Diabetes. 2009 Aug;3(3):189-91.
  3. Bain SC & Stephens JW. Exenatide and pancreatitis: an update. Expert Opin Drug Saf. 2008; 7(6):643-4.
  4. Stephens JW, Williams R. Time to stop talking about screening for diabetes? Diabet Med. 2006;23(11):1163-4. 

Published Abstracts

  1. Beaney KE, Li K, Cooper JA, Stephens JW, Humphries SE. Investigating the relationship between RS10911021 and Oxidative stress. Atherosclerosis 2014; 235 (2): E271.
  2. Gray  BJ, Bracken RM, Turner D, Morgan K, Thomas M, Williams SP, Rice S, Stephens J W. HbA1c values are associated with changes in risk scores in four commonly used validated diabetes risk assessment tools. Diabetic Medicine 2014;31 (suppl 1):16-17.
  3. SL Prior, T Oliver, DA Jones, SC Bain, SJ Hurel, SE Humphries,  JW Stephens. Association between the COX-2 rs20417 G > C variant and coronary heart disease in both Type 1 and Type 2 diabetes Diab Med. 2013; 30(11): P34.
  4. R Rai1, L Lomova-Williams, S Benjamin, A Mallipedhi1, DE Price, JW Stephens. Sitagliptin and insulin therapy in Type 2 diabetes.  Diab Med. 2013; 30(11): P452.
  5. SL Prior, K Wareham, M Williams, SC Bain, JW Stephens. Factors associated with the progression to Type 2 diabetes in a high risk sample over 12 Months. Diab Med. 2013; 30(11): P155.
  6. DA Jones, SL Prior, JN Baxter, JD Barry, SC Bain, JW Stephens. Comet analysis of visceral fat samples from patients with obesity and Type 2 diabetes. Diab Med. 2013; 30(11): P63.
  7. L Lomova-Williams, A Mallipedhi, S Benjamin, DE Price, JW Stephens. Treatment choices and targets in Type 2 diabetes and chronic kidney disease. Diab Med. 2013; 30(11): P445.
  8. EM Di Battista, JW Stephens, RM Bracken, SD Mellalieu. A conceptual framework for lifestyle interventions with health risk appraisals at the worksite: a meta-interpretation. Diab Med. 2013; 30(11): P255.
  9. BJ Gray, RM Bracken, D Turner, K Morgan, SD Mellalieu, SP Williams, M Williams, S Rice, JW Stephens. High prevalence of central obesity and raised body mass index in female local health board workers: findings of a work-based health screening initiative. Diab Med. 2013; 30(11): P516.
  10. BJ Gray, RM Bracken, D Turner, K Morgan, SD Mellalieu, SP Williams, M Williams, S Rice, JW Stephens. A work-based health screening initiative to uncover the cardiovascular and diabetes risk in male steel industry workers. Diab Med. 2013; 30(11): P517.
  11. Jones DA, Prior SL, Baxter JN, Bain SC, Stephens JW. Obesity-related Type 2 diabetes is associated with reduced gene expression of GPX1 in visceral adipose tissue. Diabetic Medicine 2011; 28(supp 1): P47.
  12. Carmen JE, Prior SL, Jones DA, Hurel SJ, Humphries SE, Stephens JW. Association between the Leu72Met polymorphism of the ghrelin gene and nephropathy in patients with diabetes. Diabetic Medicine 2011; 28(supp 1): P71.
  13. Rees DO, Bain SC, Price DE, Stephens JW. Exenatide use is not associated with changes in renal function over a six month follow-up period. Diabetic Medicine 2011; 28(supp 1): P418.
  14. Abu-Roomi SR, Rees DO, Proce DE, Boregowda K, Bain SC, Stephens JW. Experience with sitagliptin in a routine secondary care diabetes clinic. Diabetic Medicine 2011; 28(supp 1): P537.
  15. West D, Stephens J, Bain S, Bracken RM. Combined insulin reduction and carbohydrate feeding 30 min before exercise increases lipid oxidation but not risk of ketogenesis in individuals with Type 1 diabetes. Diabetic Medicine 2011; 28(supp 1): P56.
  16. Bracken RM, West D, Stephens J, Bain S. Carbohydrate oxidation rate during running is reduced with a shorter pre-exercise ingestion period following consumption of isomaltulose in Type 1 diabetes. Diabetic Medicine 2011; 28(supp 1): P57.
  17. Dacruz T, Williams M, Donoghue C, Evans C, Morgam K, Battista E, Rice S, Stephens J, Thomas M, Williams S, Brophy S, Thind M. Risk identification in the workplace for cardiovascular disease and Type 2 diabetes. Diabetic Medicine 2011; 28(supp 1): P199.
  18. Andrews K, Neil R, Stephens J, Bain S, Bracken RM. Assessment of ability of cardiac rehabilitation programme staff to manage persons with diabetes. Diabetic Medicine 2011; 28(supp 1): P367.
  19. Prior SL, Clark AR, Joes DA, Bain SC, Stephens JW. Association between the PGC-1alpha re8192678 G>A variant and nephropathy in Type 2 diabetes. Diabetic Medicine 2011; 28(supp 1): P70..
  20. Jones DA, Prior SL, Bain SC, Hurel SJ, Humphries SE, Stephens JW. Association between the rs4880 superoxide dismutase 2 (C>T) gene variant with coronary heart disease in diabetes. Diabetic Medicine 2010; 27(supp 1): A73.
  21. Tang TS, Prior SL, Li KW, Ireland HA, Bain SC, Hurel SJ, Cooper JA, Humphries SE, Stephens JW. Association between the rs1050450 glutathione peroxidase-1 (C>T) gene variant in two independent samples of subjects with diabetes. Diabetic Medicine 2010; 27 (sup 1): A74.
  22. Davies H, Brophy B, Bain SC, Stephens JW, Wakeman L, Luzio S, Williams DRR. Implementing and evaluating routine GADA testing in South Wales. Diabetic Medicine 2010; 27 (suppl 1): SD 16.
  23. Collins J, Prior SL, Jones DA, Price DE, Stephens JW. Cardiovascular risk factors should be targeted independently of glycaemic control in patients with Type 2 diabetes. Diabetic Medicine 2010; 27 (suppl 1): P27.
  24. West DJ, Morton R, Stephens J, Bain S, Bracken RM. Ingestion of a pre-exercise isomaltulose solution reduces blood glucose AUC by 21% for three hours following running in T1DM. Diabetic Medicine 2010; 27 (suppl 1): P51.
  25. West DJ, Morton R, Stephens J, Bain S, Bracken RM. A low glycaemic index meal reduces carbohydrate use during prolonged running by promoting combustion of lipids in T1DM individuals. Diabetic Medicine 2010; 27 (suppl 1): P52.
  26. Thomas R, Brenton K, Rees G, Gorvett T, Harris B, Stephens JW, Price DE. Diabetic foot ulceration is uncommon in low-risk feet within secondary care. Diabetic Medicine 2010; 27 (suppl 1): P55.
  27. Prior SL, Jones DS, Gill GV, Bain SC, Stephens JW. Adiponectin promoter gene variants and coronary heart disease risk in the “Golden Years” cohort. Diabetic Medicine 2010; 27 (suppl 1): P60.
  28. Tang YY, Tang TS, Price DE, Stephens JW. Metformin prescription in patients with Type 2 diabetes and renal impairment: clinical audit. Diabetic Medicine 2010; 27 (suppl 1): P153.
  29. Morton R, Bracken RM, West D, Edavalath M, Luzio S, Underwood P, Stephens JW. Exercise-induced hyperglycaemia: normal or abnormal? Diabetic Medicine 2010; 27 (suppl 1): P188.
  30. Brooks CJ, Collins J, Bain SC, Price DE, Ford DV, Lyons RA, Brophy S, Stephens JW. Is a better HbA1c associated with greater glucose strip prescribing? Diabetic Medicine 2010; 27 (suppl 1): P429.
  31. Tang TS, Prior SL, Williams DRR Baxter JN, Bain SC, Stephens JW. Temporal changes in glucose homeostasis following bariatric surgery in subjects with type 2 diabetes and morbid obesity. Diabetic Medicine 2009; 26 (supp 1): A5.
  32. Prior SL, Tang TS, Alam I, Baxter JN, Bain SC, Stephens JW. Total antioxidant status before and after bariatric surgery for Type 2 diabetes. Diabetic Medicine 2009; 26 (Supp 1): P121.
  33. Alam I, Lewis KE, Stephens JW, Fielding A, Lewis MJ, Hilldrup S, , Baxter JN.  Comparing long term effects of biliopancreatic diversion (BPD) versus laparoscopic gastric banding (LGB) on metabolic syndrome. BJS 2008; 95 (S7): 2. 439.
  34. Alam I, Lewis MJ, Lewis KE, Fielding A, , Hilldrup S, Stephens JW, Baxter JN. Comparison of heart rate variability parameters during open bariatric, laparoscopic bariatric and laparoscopic non bariatric procedures. BJS 2008; 95 (S7): 40. 472.
  35. Alam I, Stephens JW, Lewis LK, Baxter JN. Comparison of changes in the supine and non-supine apnoea hypopnoea index (AHI) following bariatric surgery. Am J of Resp & Crit Care Med 2008; 177: A278.
  36. Alam I, Stephens JW, Lewis LK, Lewis MJ, Baxter JN. Early and long-term effects of  biliopancreatic diversion and laparoscopic gastric banding on insulin resistance, type 2 diabetes mellitus and blood pressure in morbidly obese patients. BJS2008; 95 (S3): 52. 0531.
  37. Hancock S, Still RA, Fielding AM, Doran JF, Stephens JW. A rare cause of Cushing’s syndrome uncovers analytical discrepancies between the Roche E170 and Bayer Centaur testosterone assays. Ann Clin Biochem 2007; 44 Suppl, 88-89.
  38. Stephens JW, Dhamrait SS, Li K, Humphries SE, Hurel SJ. In vitro evidence for the antioxidant role of UCP2. Diabetic Medicine 2005; 22 (supp 2): P101.
  39. Stephens JW, Humphries SE, Miller GJ, Cooper JC, Hurel SJ. Increased oxidative stress is associated with coronary heart disease in males with diabetes mellitus and with 10-year prospective risk in males without diabetes. Diabetic Medicine 2005; 22 (supp 2): P145.
  40. Stephens JW, Hurel SJ, Ireland H, Cooper JA, Miller GJ, Humphries SE. A common functional variant in the interleukin-6 gene is associated with increased body mass index in subjects with type 2 diabetes mellitus. Diabetic Medicine 2004; 21 (supp 2): P248.
  41. Stephens JW, Cooper JA, Miller GJ, Humphries SE, Hurel SJ. The D allele of the ACE I/D common gene variant is associated with type 2 diabetes mellitus in Caucasian subjects. Diabetic Medicine 2004; 21 (supp 2): P242.
  42. Hurel SJ, Stephens JW, Humphries SE. The interleukin-6 -174G>C gene variant interacts with urinary protein excretion to increase plasma oxidative stress is subjects with type 2 diabetes. Diabetic Medicine 2004; 21 (supp 2): P237.
  43. Lunken C, Stephens JW, Gable D, Hurel SJ. Experience with insulin glargine in routine diabetes practice. Diabetic Medicine 2004; 21 (supp 2): P94.
  44. Stephens JW, Shah T, Hingorani AD, Humphries SE, Hurel SJ. A common functional variant in the CRP gene is associated with higher plasma levels of CRP in men with diabetes mellitus. Diabetic Medicine 2004; 21 (supp 2): A26.
  45. Stephens JW, Dhamrait SS, Humphries SE, Hurel SJ. The D allele of the ACE I/D gene polymorphism is associated with peripheral neuropathy in women with Type 2 Diabetes Mellitus. Diabetes 2003; 52 (supp 1): P846.
  46. Stephens JW, Ambler G, Betteridge DJ, Humphries SE, Vallance P, Hurel SJ. Cardiovascular risk prediction in diabetes. A ten year retrospective study to examine methods of risk analysis. Diabetic Medicine 2003; 20 (supp 2): A78.
  47. Stephens JW, Payne N, Humphries SE,  Hurel SJ. C-reactive protein in Diabetes & Cardiovascular disease. Diabetic Medicine 2003; 20 (supp 2): P90.
  48. Hurel SJ, Stephens JW, Humphries SE. What are the clinical manifestations of cardiovascular disease in diabetes? Diabetic Medicine 2003; 20 (supp 2): P95.
  49. Payne N, Stephens JW, Humphries SE, Hurel SJ. Plasma total antioxidant status in diabetes & cardiovascular disease. Diabetic Medicine 2003; 20 (supp 2): P92.
  50. Hurel SJ, Stephens JW, Hoyle J, Christopher T, Humphries SE. Do ACE inhibitors improve exercise performance in Type 1 diabetes? Results from a pilot study. Diabetic Medicine 2003; 20 (supp 2): P69.
  51. Trikudanathan S, Stephens JW, Jones J, Hurel SJ. Cardiovascular risk factors should be targeted independently of glycaemic control. Diabetic Medicine 2003; 20 (supp 2): P96.
  52. Stephens JW, Humphries SE, Betteridge DJ, Vallance P, Hurel SJ. Methods to predict Cardiovascular Risk: A ten year retrospective study. Diabetes 2002; 51 (supp 2): P660.
  53. Stephens JW, Betteridge DJ, Humphries SE, Hurel SJ. Cardiovascular risk prediction: are the charts good enough? A 10-year retrospective study. Diabetic Medicine 2002; 19 (supp2): A57.
  54. Stephens JW, Morganstein DL, Bannister B, Dorwood N, Bouloux PM-G. Tuberculous hypophisitis-An unusual cause of hypopituitarism. Endocrine Abstracts 2001; 2: P13.
  55. Stephens JW, Buttriss D, Payne N, Barker SGE, Hurel SJ. Subcutaneous Insulin delivery without a needle: Evaluation of the J-tip® delivery system. Diabetic Medicine 2001;18: P276.
  56. Stephens JW, Flossmann O, Katz M, Conway GS. Medical disorders and the menstrual cycle. Journal of Endocrinology 2000; 167 (supp): P29.
  57. Stephens JW, Latiff N, Stanhope R, Conway GS. Metformin: The regulation of the menstrual cycle in polycystic ovary syndrome. Journal of Endocrinology 2000; 167 (supp): P72.
  58. Ames PRJ, Steuer A, Stephens J, Denman AM. Thrombosis in Behcet syndrome. A survey of 75 Caucasian patients on long term follow up. Arthritis & Rheumatism 1996; 39,9 (supp):1205.
  59. Carey AH, Merrin PK, Stephens J, Williamson R, Franks S. Evidence for dysfunctional insulin secretion in families of women presenting with polycystic ovary syndrome. Journal of Endocrinology 1994;149 (supp):P235.
  60. Stephens J, Carey AH, Short F, Williamson R, Franks S. Premature balding, the male phenotype of polycystic ovaries. Journal of Endocrinology 1993; 139 (supp): A031.

 

 

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