611 Grosse Pointe Cir
Vernon Hills, IL 60061
Phone: 786-4930449
E-mail: singhrkbio@gmail.com
Education
1994-2000 | Ph.D. Biochemistry (Molecular Toxicology) | Department of Biochemistry, Dr. R.M.L Avadh University, Faizabad, India |
1991-1993 | M.S. Biochemistry, Minor in Plant Pathology | Department of Biochemistry, N.D University of Agri. Technology, Faizabad, India |
1986-1990 | B.S Agriculture. Minor in Biochemistry | College of Agriculture, N.D. University of Agri. Technology, Faizabad, India |
Biography
Research Interest
Scientific Activities
Honors and Awards
2009 | Travel Award | AACR Annual meeting, Denver |
2007 | Travel Award | International Forum for Public Health Meeting, Shanghai, China |
2005 | Excellence in Research Award | Metal Specialty Section, Society of Toxicology, New Orleans |
Professional Memberships
- American Association For Cancer Research (AACR)
- Society of Toxicology (SOT)
- Michigan Society of Toxicology
- Genetics and Environmental Mutagenesis Society (GEMS)
Professonal Experince
November 2016-Present | Toxicologist | Vyaire Medical/CareFusion | Vernon Hills, IL |
July 2011-Octuber 2016 | Associate EHS Specialist (Toxicology Specialist) | Health & Environmental Sciences | Dow Corning Corporation, Midland, MI |
July 2006-June 2011 | Research Scientist | Department of Urology | Miller School of Medicine, University of Miami, Miami, FL |
Oct 2003-June 2006 | Postdoctoral Research Fellow | Department of Pathology | School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND |
Jan 2001- Sept 2003 | Research Fellow | Department of Horticulture N.D | University of Agriculture & Technology, Faizabad, India |
Publications
- Kallifatidis G , Munoz D , Singh RK, Salazar N, Hoy JJ and Lokeshwar BL (2016). Beta-Arrestin-2 Counters CXCR7-mediated EGFR Transactivation and Proliferation. Molecular Cancer Research. Feb 26, 2016.
- Salazar N, Munoz D, Kallifatidis G, Singh RK, Jordz M and Lokeshwar BL (2014). The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation. Molecular Cancer 13; 198.
- Singh RK and Lokeshwar BL (2011).The IL-8 regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth. Cancer Research 71: 3268-77.
- Singh RK, Sudhakar A, and Lokeshwar BL (2011). From normal cells to malignancy: Distinct Role of Pro-inflammatory factors and cellular redox mechanisms. J Cancer Sci. Ther. 3: 070-075 (Invited Review, Corresponding Author).
- Singh RK, Sudhakar A, and Lokeshwar BL (2010). Role of chemokines and chemokine receptors in prostate cancer development and progression. J Cancer Sci. Ther. 2: 094-099. (Invited Review, Corresponding Author).
- Singh RK and Lokeshwar BL (2009). Depletion of intrinsic expression of interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherauptic drugs. Molecular Cancer 8: 57.
- Singh RK, Amy LA, Somji S, Sens MA, Sens DA and Garrett SH (2008). Alterations in metal toxicity and metal-induced metallothionein gene expression elicited by growth medium calcium concentration. Cell Biol. Toxicol. 24:273–281.
- Amy LA, Singh RK, Somji S, Sens MA, Sens DA and Garrett SH (2008). Basal and metal-induced expression of metallothionein isoform 1 and 2 genes in the RWPE-1 human prostate epithelial cell line. J Appl. Toxicol 28: 283–293.
- Araki S, Omori Y, Lyn D, Singh R K, Meinbach DM, Sandman Y, Lokeshwar VB and Lokeshwar BL(2007). IL-8 is a molecular determinant of androgen independence and progression in prostate cancer. Cancer Research 67 (14) 6854-6862.
- Dong XZ, Sens DA, Sens MA, Venugopal NBRK, Singh RK, Garrett SH and Somji S (2006). Metallothionein-1 and 2 expressions in heavy metal-derived human malignant urothelial cells and tumor heterotransplants as a prognostic indicator in human bladder cancer. Toxicological Sciences 91 (2) 467-75.
- Garrett SH, Park S, Sens MA, Somji S, Singh RK, Venugopal NBRK and Sens DA (2005). Expression of metallothoinein isoform 3 is restricted at the post-transcriptional level in human bladder epithelial cells. Toxicological Sciences 87 (1): 66-74.
- Singh RK and Sharma B (2005). Sub-acute toxicity of carbofuran on acetylcholinesterase in the freshwater cat-fish, Clarias batrachus. Environ. Occup. Med 22: 403-407.
- Singh RK and Sharma B (2004). In vivo alteration in protein metabolism by sub-acute carbofuran in freshwater teleost, Clarias batrachus. Bull. Environ. Contam. Toxicol 73: 919-926. (Corresponding Author).
- Singh R K, Singh RL and Sharma B (2003). Acute toxicity of carbofuran to freshwater teleost, Clarias batrachus. Bull. Environ. Contam. Toxicol 76 (6):1070-75 (Corresponding Author).
- Singh RK and Sharma B (1998). Carbofuran-induced biochemical changes in Clarias batrachus. Pesticide Science 53: 285-290.
- Yadav A, Singh RK and Sharma B (1998). Interaction of carbofuran with acetylcholinesterase from the brain of teleost, Clarias batrachus. Environ. Toxicol. Chem. 65: 245-254.
- Kumari R, Singh RK, Khanna YP and Sharma B (1997). Carbofuran induced stress mediated syndromes in Clarias batrachus. Proc. Int. Conf. Indus. Poll. Control Technol. pp. 113-119.