rajendra-k
Rajendra K Singh, PhD

611 Grosse Pointe Cir
Vernon Hills, IL 60061
Phone: 786-4930449
E-mail: singhrkbio@gmail.com

Education

1994-2000 Ph.D. Biochemistry (Molecular Toxicology) Department of Biochemistry, Dr. R.M.L Avadh University, Faizabad, India
1991-1993 M.S. Biochemistry, Minor in Plant Pathology Department of Biochemistry, N.D University of Agri. Technology, Faizabad, India
1986-1990 B.S Agriculture. Minor in Biochemistry College of Agriculture, N.D. University of Agri. Technology, Faizabad, India

Biography

Research Interest

Scientific Activities

Honors and Awards

2009 Travel Award AACR Annual meeting, Denver
2007 Travel Award International Forum for Public Health Meeting, Shanghai, China
2005 Excellence in Research Award Metal Specialty Section, Society of Toxicology, New Orleans
Professional Memberships
  • American Association For Cancer Research (AACR)
  • Society of Toxicology (SOT)
  • Michigan Society of Toxicology
  • Genetics and Environmental Mutagenesis Society (GEMS)
Professonal Experince

November 2016-Present Toxicologist Vyaire Medical/CareFusion Vernon Hills, IL
July 2011-Octuber 2016 Associate EHS Specialist (Toxicology Specialist) Health & Environmental Sciences Dow Corning Corporation, Midland, MI
July 2006-June 2011 Research Scientist Department of Urology Miller School of Medicine, University of Miami, Miami, FL
Oct 2003-June 2006 Postdoctoral Research Fellow Department of Pathology School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND
Jan 2001- Sept 2003 Research Fellow Department of Horticulture N.D University of Agriculture & Technology, Faizabad, India

Publications

  1. Kallifatidis G , Munoz D , Singh RK, Salazar N, Hoy JJ and Lokeshwar BL (2016). Beta-Arrestin-2 Counters CXCR7-mediated EGFR Transactivation and Proliferation. Molecular Cancer Research. Feb 26, 2016.
  2. Salazar N, Munoz D, Kallifatidis G, Singh RK, Jordz M and Lokeshwar BL (2014). The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation. Molecular Cancer 13; 198.
  3. Singh RK and Lokeshwar BL (2011).The IL-8 regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth. Cancer Research 71: 3268-77.
  4. Singh RK, Sudhakar A, and Lokeshwar BL (2011). From normal cells to malignancy: Distinct Role of Pro-inflammatory factors and cellular redox mechanisms. J Cancer Sci. Ther. 3: 070-075 (Invited Review, Corresponding Author).
  5. Singh RK, Sudhakar A, and Lokeshwar BL (2010). Role of chemokines and chemokine receptors in prostate cancer development and progression. J Cancer Sci. Ther. 2: 094-099. (Invited Review, Corresponding Author).
  6. Singh RK and Lokeshwar BL (2009). Depletion of intrinsic expression of interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherauptic drugs. Molecular Cancer 8: 57.
  7. Singh RK, Amy LA, Somji S, Sens MA, Sens DA and Garrett SH (2008). Alterations in metal toxicity and metal-induced metallothionein gene expression elicited by growth medium calcium concentration. Cell Biol. Toxicol. 24:273–281.
  8. Amy LA, Singh RK, Somji S, Sens MA, Sens DA and Garrett SH (2008). Basal and metal-induced expression of metallothionein isoform 1 and 2 genes in the RWPE-1 human prostate epithelial cell line. J Appl. Toxicol 28: 283–293.
  9. Araki S, Omori Y, Lyn D, Singh R K, Meinbach DM, Sandman Y, Lokeshwar VB and Lokeshwar BL(2007). IL-8 is a molecular determinant of androgen independence and progression in prostate cancer. Cancer Research 67 (14) 6854-6862.
  10. Dong XZ, Sens DA, Sens MA, Venugopal NBRK, Singh RK, Garrett SH and Somji S (2006). Metallothionein-1 and 2 expressions in heavy metal-derived human malignant urothelial cells and tumor heterotransplants as a prognostic indicator in human bladder cancer. Toxicological Sciences 91 (2) 467-75.
  11. Garrett SH, Park S, Sens MA, Somji S, Singh RK, Venugopal NBRK and Sens DA (2005). Expression of metallothoinein isoform 3 is restricted at the post-transcriptional level in human bladder epithelial cells. Toxicological Sciences 87 (1): 66-74.
  12. Singh RK and Sharma B (2005). Sub-acute toxicity of carbofuran on acetylcholinesterase in the freshwater cat-fish, Clarias batrachus. Environ. Occup. Med 22: 403-407.
  13. Singh RK and Sharma B (2004). In vivo alteration in protein metabolism by sub-acute carbofuran in freshwater teleost, Clarias batrachus. Bull. Environ. Contam. Toxicol 73: 919-926. (Corresponding Author).
  14. Singh R K, Singh RL and Sharma B (2003). Acute toxicity of carbofuran to freshwater teleost, Clarias batrachus. Bull. Environ. Contam. Toxicol 76 (6):1070-75 (Corresponding Author).
  15. Singh RK and Sharma B (1998). Carbofuran-induced biochemical changes in Clarias batrachus. Pesticide Science 53: 285-290.
  16. Yadav A, Singh RK and Sharma B (1998). Interaction of carbofuran with acetylcholinesterase from the brain of teleost, Clarias batrachus. Environ. Toxicol. Chem. 65: 245-254.
  17. Kumari R, Singh RK, Khanna YP and Sharma B (1997). Carbofuran induced stress mediated syndromes in Clarias batrachus. Proc. Int. Conf. Indus. Poll. Control Technol. pp. 113-119.

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