Sampath Parthasarathy
Associate Dean for Research, Professor of Medicine

University of Central Florida
Florida, USA
Phone: 407-266-7121


Year  Degree Institution
1964-1967     B.Sc University of Madras, India
1967-1969    M.Sc University of Madras, India
1969-1975     Ph.D. Indian Institute of Science, India
1985-1987 Prof. Cert. Management University of California, San Diego
2003-2005  M.B.A (Technology) University of Phoenix


Dr. Sampath Parthasarathy, Ph.D., MBA is an internationally known cardiovascular scientist who holds the UCF College of Medicine’s Florida Hospital Endowed Chair in Cardiovascular Sciences. Before joining the college’s Burnett School of Biomedical Sciences November of 2011, He  held the Klassen Chair of Cardiothoracic surgery at Ohio State University.

He is a recognized expert in lipids who is credited with the co-discovery of a major cardiovascular concept - the fact that oxidized LDL is involved in the initiation and progression of atherosclerosis. His areas of interest include atherosclerosis, diabetes, heart failure, and cardiovascular nutrition.

Dr. Parthasarathy has a breadth of research experience, including studies on endometriosisand aspirin. He has published over 280 original articles and has won several meritorious awards. His work is extensively funded by the National Institute of Health (NIH) and AHA and he belongs to an elite group of the most highly cited authors worldwide in his field. He has served on numerous NIH/AHA committees and is a member of the editorial boards of many journals.

Dr. Parthasarathy received his Ph.D. from the Indian Institute of Science and did post-doctoral training at Duke University and the University of Minnesota. In addition to The Ohio State, he has served as a faculty at the University of California, San Diego, Emory University and Louisiana State University. Dr. Parthasarathy also is an inventor and has a MBA degree in Technology Management.

Research Interest

  • Atherosclerosis
  • Lipids and Lipoproteins
  • Antioxidants and oxidative stress
  • Macrophage biology
  • Crohn’s Disease and other inflammatory diseases
  • Diabetes and obesity

Scientific Activities

Professional Memberships
  • Secretary, South Asian Society for Atherosclerosis and Thrombosis, 1994-2002
  • Executive Secretary: South Asian Society for Atherosclerosis and Thrombosis, 2002-
  • AHA Lipoprotein and Lipid Metabolism Committee, 1991-1994
  • AHA, Program Committee Council on Atherosclerosis, 1996-1997
  • AHA, Membership/Credentials Committee, Council on ATVB, 1997-2002
  • AHA, Nominating Committee, Arteriosclerosis., Thrombosis and Vascular Biology, 1998-2002
  • National Heart, Lung and Blood Institute (NHLBI), Program Project Review, 1994-1996
  • AHA Executive Committee, Council on ATVB 2000-2004
  • Department of VA Merit Review Subcommittee for Cardiovascular Studies, 2001-2004
  • AHA review panel in vessel wall biology, 2002-2003
  • Peer Review Committee-AHA Ohio Valley Affiliate 2007-2010
  • Peer Review Committee-AHA National affiliate 2007-
  • Elected member-Deuel Board
  • Numerous NIH review committees over 3 decades
  • Meeting organizational committees, Review committees for US, UK, Netherlands, New Zealand, Canada, Qatar, India, and several other countries.
  • Institutional Review Board committees (LSU and The Ohio State University)
  • Grievance Committee (The Ohio State University)
  • National VA review committee
UCF Committees
  • COM Enterprise committee
  • COM Executive committee
  • COM-Finance sub-committee
  • Co-Chair COM Wellness committee
  • UCF-EHS Director search committee
  • UCF-Space committee
  • UCF-Thematic Team-Chair-Initiative 3-Research
Honors and Awards
  1. Achievement Award for Contribution to Vascular Biology, American Cardiologist of Indian Origin, 1995
  2. Achievement Award for Contribution to Medical Research, South Asian Society for Atherosclerosis, Thrombosis, and Transfusion Medicine, 1998.
  3. Special Recognition Award, American Heart Association, Council on Arteriosclerosis, Thrombosis and Vascular Biology, 1998
  4. Dr. Lalitha Kameswaran Oration-2002
  5. Dr. Jerome Markovits Gold Medal for Achievements in Cardiovascular Sciences, 2002
  6. Van Deenen Memorial Lecture, ICBL, Greece, 2004
  7. Ranbaxy Science Foundation-Medical Science award, New Delhi, 2009
  8. Davis Heart Lung Research Institute, Distinguished Mentor 2009
  9. Distinguished service award-International Academy of Cardiovascular Sciences, 2017
  10. Many plenary and invited lectures and inaugural addresses


  1. Parthasarathy S, Ganguly J. 1973. A simple biosynthetic method for the preparation of glycerol-labeled phosphatidylcholine. Biochem Biophys Acta 296:62‑64.
  2. Parthasarathy S, Subbaiah PV, Ganguly J. 1974. The mechanism of intestinal absorption of phosphatidylcholine in rats. Biochem J 140:503-508.
  3. Kamiryo T, Parthasarathy S, Numa S. 1976. Evidence that acyl coenzyme A synthetase activity is required for the repression of yeast acetyl coenzyme A carboxylase by exogenous fatty acids. Proc Natl Acad Sci USA 73:386‑390.
  4. Kamiryo T, Parthasarathy S, Mishina M, Iida Y, Numa S. 1976. Isolation of Saccharomyces cerevisiae mutants defective in acyl coenzyme A synthetase. Agric Biol Chem 41:1295‑1301.
  5. Parthasarathy S, Cady RK, Kraushaar DS, Sladek NE, Baumann WJ. 1978. Inhibition of diacylglycerol: CDP-choline cholinephosphotransferase activity by dimethylaminoethyl p‑chlorophenoxyacetate. Lipids 13:161‑164.
  6. Paul P, Ramesha CS, Parthasarathy S, Ganguly J. 1978. Effect of dietary lipids on the secretion of biliary lipids in rats.  Indian J Biochem Biophys 15:401‑406.
  7. Parthasarathy S, Lin JT, Baumann WJ. 1979. Ethanediol monoester hydrolysis by monoacylglycerol lipase of rat liver microsomes. Biochem Biophys Acta 573:107‑113.
  8. Mansbach CM, Parthasarathy S. 1979. Regulation of de novo phosphatidylcholine synthesis in rat intestine. J Biol Chem 254:9688‑9694.
  9. Parthasarathy S, Baumann WJ. 1979. Lysolecithin as regulator of de novo lecithin synthesis in rat liver microsomes. Biochem Biophys Res Commun 91:637‑642.
  10. Hayase K, Parthasarathy S, Eppler CM, Baumann WJ. 1980. A rapid assay of acyl-coenzyme A: lysolecithin acyltransferase activity. J Lipid Res 21:484‑488.
  11. Parthasarathy S, Murari R, Crilly KS, Baumann WJ. 1981. Modulation of diacylglycerol acyltransferase by lysolecithin and related monochain phospholipids. Biochem Biophys Acta 664:249‑254.
  12. Malewicz B, Parthasarathy S, Jenkin HM, Baumann WJ. 1981. Rapid phospholipase A2 stimulation and diacylglycerol cholinephosphotransferase inhibition in baby hamster kidney cells during initiation of dengue virus infection. Biochem Biophys Res Commun 101:404‑410.
  13. Parthasarathy S, Abd El-Rahman MMA, Baumann WJ. 1981. Modulation of phosphatidylcholine synthesis in vitro: Inhibition of diacylglycerol cholinephosphotransferase and lysophosphatidyl­choline acyltransferase by centrophenoxine and neophenoxine. Biochem Biophys Acta 665:345‑351.
  14. Murari R, Abd El-Rahman MMA, Wedmid Y, Parthasarathy S, Baumann WJ. 1982. Carbon-13 nuclear magnetic resonance spectroscopy of phospholipids in solution. Spectral and stereochemical assignments based on 13C‑31P and 13C‑14N couplings. J Org Chem 47:2158‑2163.
  15. Dyck PJ, Lais AC, Hansen SM, Sparks MF, Low PA, Parthasarathy S, Baumann WJ. 1982. Technique assessment of demyelination from endoneurial injection. Exp Neurol 77:359‑377.
  16. Parthasarathy S, Kritchevsky D, Baumann WJ. 1982. Hypolipidemic drugs are inhibitors of phosphatidylcholine synthesis. Proc Natl Acad Sci USA 79:6890‑6893.
  17. Mansbach CM, Parthasarathy S. 1982. A re‑examination of the fate of glyceride‑glycerol in neutral lipid absorption and transport. J Lipid Res 23:1009‑1019.
  18. Low PA, Schmelzer JD, Yao JK, Dyck, PJ, Parthasarathy S, Baumann WJ. 1983. Structural specificity in demyelination induced by lysophospholipids. Biochem Biophys Acta 754:298‑304.
  19. Steinbrecher UP, Parthasarathy S, Leake DS, Witztum JL, Steinberg D. 1984. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc Natl Acad Sci USA 81:3883‑3887.
  20. Parthasarathy S, Steinbrecher UP, Barnett J, Witztum JL, Steinberg D. 1985. Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein. Proc Natl Acad Sci USA 82:3000‑3004.
  21. Quinn MT, Parthasarathy S, Steinberg D. 1985. Endothelial cell‑derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of low density lipoprotein. Proc Natl Acad Sci USA 82:5949‑5953.
  22. Parthasarathy S, Young SG, Witztum JL, Pittman RC, Steinberg D. 1986. Probucol inhibits oxidative modification of low density lipoprotein. J Clin Invest 77:641‑644.
  23. Parthasarathy S, Printz DJ, Boyd D, Joy L, Steinberg D. 1986. Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor. Arteriosclerosis 6:505‑510.
  24. Parthasarathy S, Fong LG, Otero D, Steinberg D. 1987. Recognition of solubilized apoproteins from dilapidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor. Proc Natl Acad Sci USA 84:537-540.
  25. Parthasarathy S. 1987. Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor. Biochem Biophys Acta 917:337-340.
  26. Quinn MT, Parthasarathy S, Fong LG, Steinberg D. 1987. Oxidatively modified low density lipoproteins: A potential role in recruitment and retention of monocyte/ macrophages during atherogenesis. Proc Natl Acad Sci USA 84:2995-2998.
  27. Steinbrecher UP, Witztum JL, Parthasarathy S, Steinberg D. 1987. Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism. Arteriosclerosis 7:135-143.
  28. Fong LG, Parthasarathy S, Witztum JL, Steinberg D. 1987. Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B-100. J Lipid Res 28:1466-1477.
  29. Sparrow CP, Parthasarathy S, Steinberg D. 1988. Enzymatic modification of low density lipoprotein by purified lipoxygenase plus phospholipase A2 mimics cell-mediated oxidative modification. J Lipid Res 29:745-753.
  30. Quinn MT, Parthasarathy S, Steinberg D. 1988. Lyso­phosphatidylcholine: A chemotactic factor for human monocytes and its potential role in atherogenesis.  Proc Natl Acad Sci USA 85:2805-2809.
  31. Bird JE, Milhoan K, Wilson CB, Young SG, Mundy CA, Parthasarathy S, Blantz RC. 1989. Ischemic acute renal failure and antioxidant therapy in the rat. The relation between glomerular and tubular dysfunction.  J Clin Invest 81:630-1638.
  32. Sparrow CP, Parthasarathy S, Steinberg D. 1989. A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein. J Biol Chem 264:2599-2604.
  33. Parthasarathy S, Wieland E, Steinberg D. 1989. A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein. Proc Natl Acad Sci USA 86:1046-1050.
  34. Palinski W, Rosenfeld ME, Yla-Herttuala S, Gurtner GC, Socher SS, Butler SW, Parthasarathy S, Carew TE, Steinberg D, Witztum JW. 1989. Low density lipoprotein undergoes oxidative modification in vivo.  Proc Natl Acad Sci USA 86:1372-1376.
  35. Parthasarathy S, Quinn MT, Schwenke DC, Carew TE, Steinberg D. 1989. Oxidative modification of beta-very low density lipoprotein: Potential role in monocyte recruitment and foam cell formation. Arteriosclerosis 9:398-404.
  36. Ylä-Herttuala S, Palinski W, Rosenfeld ME, Parthasarathy S, Carew TE, Butler S, Witztum JL, Steinberg D. 1989. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J Clin Invest 84:1086-1095.
  37. Parthasarathy S, Barnett J, Fong LG. 1990. High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein. Biochem Biophys Acta 1044:275-283.
  38. Palinski W, Ylä-Herttuala S, Rosenfeld ME, Butler S, Socher SA, Parthasarathy S, Curtiss LK, Witztum JL. 1990. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein. Arteriosclerosis 10:325-335.
  39. Parthasarathy S, Khoo JC, Miller E, Barnett J, Witztum JL, Steinberg D. 1990. Low density lipoprotein rich in oleic acid is protected against oxidative modification: Implications for dietary prevention of atherosclerosis.  Proc Natl Acad Sci USA 87:3894-3898.
  40. Kalyanaraman B, Antholine WE, Parthasarathy S. 1990. Oxidation of low-density lipoprotein by Cu2+ and lipoxygenase: an electron spin resonance study. Biochim Biophys Acta 1035:286-292.
  41. Ylä-Herttuala S, Rosenfeld ME, Parthasarathy S, Glass CK, Sigal E, Witztum JL, Steinberg D. 1990. Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions. Proc Natl Acad Sci USA 87:6959-6963.
  42. Murari MP, Murari R, Parthasarathy S, Guy CA, Kumar VV, Malewicz B, Baumann WJ. 1990. Lyso platelet activating factor (lyso PAF) and its enantiomer. Total synthesis and carbon-13 NMR spectroscopy. Lipids 25:606-612.
  43. Parthasarathy S, Barnett J. 1990. Phospholipase A2 activity of low density lipoprotein: Evidence for an intrinsic phospholipase A2 activity of apoprotein B-100. Proc Natl Acad Sci USA 87:9741-9745.
  44. Rosenfeld ME, Khoo JC, Miller E,  Parthasarathy S, Palinski W, Witztum JL. 1991. Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts. J Clin Invest 87:90-99.
  45. Rankin SM, Parthasarathy S, Steinberg D. 1991. Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages. J Lipid Res 32:449-456.
  46. Kalyanaraman B, Joseph J, Parthasarathy S. 1991. The spin trap, α-phenyl N-tert-butylnitrone, inhibits the oxidative modification of low density lipoprotein. FEBS Letters 280:17-20.
  47. Kalyanaraman B, Parthasarathy S, Joseph J, Froncisz W. 1991. EPR Spectra in a Loop-Gap resonator for a spin -trapped radical from a low-density lipoprotein lipid. J Magnetic Resonance 92:342-347.
  48. Ylä-Herttuala S, Rosenfeld ME, Parthasarathy S, Sigal E, Särkioja T, Witztum JL, Steinberg D. 1991. Gene expression in macrophage-rich human atherosclerotic lesions. 15-Lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts. J Clin Invest 87:1146-1152.
  49. Quinn MT, Kondratenko N, Parthasarathy S. 1991. Analysis of the monocyte chemotactic response to lysophosphatidylcholine: role of lysophospholipase C. Biochem Biophys Acta 1082:293-302.
  50. Reaven PD, Parthasarathy S, Grasse BJ, Miller E, Almazan F, Mattson FH, Khoo JC, Steinberg D, Witztum JL. 1991. Feasibility of using an oleate-rich diet to reduce the susceptibility of low-density lipoprotein to oxidative modification in man. Am J Clin Nutr 54:701-706.
  51. Kalyanaraman B, Darley-Usmar VM, Woods J, Joseph J, Parthasarathy S. 1992. Synergistic interaction between the probucol phenoxy radical and ascorbic acid in inhibiting the oxidation of low density lipoprotein. J Biol Chem 267:6789-6795.
  52. Parthasarathy S. 1992. Evidence for an additional intracellular site of action of probucol in the prevention of oxidative modification of low density lipoprotein. Use of a new water-soluble probucol derivative.  J Clin Invest 89:1618-1621.
  53. Reaven PD, Parthasarathy S, Beltz WF, Witztum JL. 1992. Effect of probucol dosage on plasma lipid and lipoprotein levels and on protection of low density lipoprotein against in vitro oxidation in humans. Arteriosclerosis and Thrombosis 12:318-324.
  54. Picard S, Parthasarathy S, Freubis J, Witztum JL. 1992. Aminoguanidine inhibits oxidative modification of low density lipoprotein and the subsequent increase in uptake by macrophage scavenger receptors. Proc Natl Acad Sci USA 89:6876-6880.
  55. Kalyanaraman B, Joseph J, Kondratenko N, Parthasarathy S. 1992. Direct modification of low density lipoprotein by the spin trap 3,5-dibromo-4-nitrosobenzene sulfonic acid. Biochem Biophys Acta 1126:309-313.
  56. Moulton KS, Wu H, Barnett J, Parthasarathy S, Glass CG. 1992. Regulated expression of the human acetylated low density lipoprotein receptor gene and isolation of promoter sequences.  Proc Natl Acad Sci USA 89:8102-8106.
  57. Fruebis J, Parthasarathy S, Steinberg D. 1992. Evidence for a concerted reaction between lipid hydroperoxides and polypeptides. Proc Natl Acad Sci USA 89:10588-10592.
  58. Reaven PD, Parthasarathy S, Grasse BJ, Miller E, Steinberg D, Witztum JL. 1993. Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects. J Clin Invest 91:668-676.
  59. McMurray HF, Parthasarathy S, Steinberg D. 1993. Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes. J Clin Invest 92:1004-1008.
  60. Reaven PR, Khouw A, Beltz WF, Parthasarathy S, Witztum JL. 1993. Effect of dietary antioxidant combinations in humans. Protection of Low Density LDL by Vitamin E, but not by β-Carotene.  Arteriosclerosis and Thrombosis 13:590-600.
  61. Kalyanaraman B, Joseph J, Parthasarathy S. 1993. Site-specific trapping of reactive species in low density lipoprotein oxidation: biological implications. Biochem Biophys Acta 1168:220-227.
  62. Wieland E, Parthasarathy S, Steinberg D. 1993. Peroxidase-dependent metal-independent oxidation of low density lipoprotein in vitro. A model for in vivo oxidation?  Proc Natl Acad Sci USA 90:5929-5933.
  63. Khouw AS, Parthasarathy S, Witztum JL. 1993. Radioiodination of low density lipoprotein initiates lipid peroxidation: protection by use of antioxidants. J Lipid Res 34:1483-1496.
  64. Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S. 1993. Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. FEBS Letters 334:170-174.
  65. Sambrano GR, Parthasarathy S, Steinberg D. 1994. Recognition of oxidatively damaged erthrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein. Proc Natl Acad Sci USA 91:3265-3269.
  66. Calcutt NA, McMurray HF, Moorhouse DF, Bache M, Parthasarathy S, et al. 1994. Inhibition of macrophage chemotaxis and peripheral nerve regeneration in normal and hyperglycemic rats by the aldose reductase inhibitor tolrestat.  Exptl Neurol 128:226-232.
  67. Khan BV, Parthasarathy S, Alexander RW, Medford RM. 1994. Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells. J Clin Invest 95:1262-1270.
  68. Ottnad E, Parthasarathy S, Sambrano GR, et al. 1995. A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells. Proc Natl Acad Sci USA 92:1391-1395.
  69. Parthasarathy S, Morales AJ, Murphy AA. 1995. Antioxidant: a new role for RU-486 and related compounds. J Clin Invest 94:1990-1995.
  70. Kalyanaraman B, Darley-Usmar V, Struck A, Hogg N, Parthasarathy S. 1995. Role of apolipoprotein B-derived radical and α-tocopheroxyl radical in peroxidase-dependent oxidation of low density lipoprotein.  J Lipid Res 36:1037-1045.
  71. Santanam N, Parthasarathy S. 1995. Paradoxical actions of antioxidants in the oxidation of low density lipoprotein by peroxidases. J Clin Invest 95:2594-2600.
  72. Lipton BA, Parthasarathy S, Ord VA, Clinton SK, Libby, Rosenfeld ME. 1995. Components of the protein fraction of oxidized low density lipoprotein stimulate interleukin-1α production by rabbit arterial macrophage-derived foam cells. J Lipid Res 36:2232-2242.
  73. Philis-Tsimikas A, Parthasarathy S, Picard S, Palinski W, Witztum JL. 1995. Aminoguanidine has both pro-oxidant and antioxidant activity toward LDL. Arterioscler Thromb Vasc Biol 15:367-376.
  74. Benz DJ, Mol M, Ezarki M, Mori-Ito N, Zelan I, Miyanohara A, Friedmann T, Parthasarathy S, Steinberg D, Witztum JL. 1995.  Enhanced levels of lipoperoxides in low density lipoprotein incubated with murine fibroblasts expressing high levels of human 15-lipoxygenase. J Biol Chem 270:5191-5197.
  75. Santanam N, Parthasarathy S. 1995. Cellular cysteine generation does not contribute to the initiation of LDL oxidation. J Lipid Res 36:2203-2211.
  76. Natarajan V, Scribner WM, Hart CM, Parthasarathy S. 1995. Oxidized low density lipoprotein-mediated activation of phospholipase D in smooth muscle cells: a possible role in cell proliferation and atherogenesis. J Lipid Res 36:2005-2016.
  77. Hogg N, Struck A, Goss SPA, Santanam N, Joseph NJ, Parthasarathy S, Kalyanaraman B. 1995. Inhibition of macrophage-dependent low density lipoprotein oxidation by nitric oxide donors. J Lipid Res 36:1756-1762.
  78. Roberts CP, Parthasarathy S, Gulati R, Horowitz I, Murphy AA. 1995. Effect of RU-486 and related compounds on the proliferation of cultured macrophages. J Repro Immunol 34:248-256.
  79. Rubbo H, Parthasarathy S, Barnes S, Kirk M, Kalyanaraman B, Freeman BA. 1995. Nitric oxide inhibition of lipoxygenase-dependent liposome and low-density lipoprotein oxidation: Termination of radical chain propagation reactions and formation of nitrogen-containing oxidized lipid derivatives. Arch Biochem Biophys 324:15-25.
  80. Roberts CP, Santanam N, Parthasarathy S, Murphy AA. 1996. The effect of RU486 and related compounds on cultured macrophage differentiation and function. Am J Obstet Gynecol 175:248-59.
  81. Carpenter SE, Santanam N, Murphy AA, Rock JA, Parthasarathy S. 1996. Inhibition of oxidative modification of proteins by RU486.  Fertility and Sterility 66:90-94.
  82. Feng TI, Raynor BD, Santanam N, Parthasarathy S. 1996. Soluble vascular cell adhesion molecule-1 levels in maternal and cord blood.  J Matern Fetal Invest 6:124-144.
  83. Chen, L., Haught, H., Yang, B., Saldeen, T., Parthasarathy, S., Mehta, J.  1997.  Preservation of endogenous antioxidant activity and inhibition of lipid peroxidation as common mechanisms of aniatherosclerotic effects of Vitamin E, lovastatin Amlodipine.  J Am Coll Cardiol 30;569-75. 
  84. Kim JG, Sabbagh F, Santanam S, Wilcox JN, Medford RM, Parthasarathy S. 1997. Generation of a polyclonal  antibody against lipid peroxide-modified proteins.  Free Radical Biology & Medicine 23:251-259.
  85. Raynor BD, Parthasarathy S. 1997. Maternal Serum Vascular Cell Adhesion Molecule Concentration During Pregnancy. J Soc Gynecol Invest 4:78-80.
  86. Santanam N, Sanchez R, Hendler S, Parthasarathy S. 1997. Aqueous extracts of cigarette smoke promote the oxidation of low density lipoprotein by peroxidases. FEBS Letters 414:549-551.
  87. Kim JG, Rock JA, Murphy AA, Parthasarathy S. 1997. Charge-based interactions of mammalian sperm with oocytes: inhibition of fertilization of mouse oocytes by ligands of macrophage scavenger receptor(s).  Fertility and Sterility 68:1108-1113.
  88. Kim JG, Keshava C, Murphy AA, Pitas RE, Parthasarathy S. 1997. Fresh mouse peritoneal macrophages have low scavenger receptor activity. J Lipid Res 38:2207-2215.
  89. Ramasamy S, Parthasarathy S, Harrison DG. 1998. Regulation of endothelial nitric oxide synthase gene expression by oxidized linoleic acid. J Lipid Res 39:268-276.
  90. Reddy S, Santanam N, Reddy PP, Rock JA, Murphy AA, Parthasarathy S. 1998. Interaction of interceed oxidized regenerated cellulose with macrophages: a potential mechanism by which interceed may prevent adhesions.  Am J Obstet Gynecol 177:1315-1321.
  91. Poddar AS, Kim JG, Gill KP, Bates BN, Santanam N, Rock JA, Murphy AA, Parthasarathy S. 1998.  Generation and characterization of a polyclonal anti-peptide antibody to human glycodelin.  Fertility and Sterility 69:543-548.
  92. Wetzstein CJ, Shern-Brewer RA, Santanam N, Green NR, White-Welkley JE, Parthasarathy S. 1998. Does acute exercise affect the susceptibility of low density lipoprotein to oxidation? Free Radical Biology & Medicine 24:679-682.
  93. Ferguson E, Parthasarathy S, Joseph J, Kalyanaraman B. 1998. Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low-density lipoprotein. J Lipid Res 39:925-933.
  94. Murphy AA, Palinski W, Rankin S, Morales AJ, Parthasarathy S. 1998. Evidence for oxidatively modified lipid-protein complexes in endometrium and endometriosis. Fertility and Sterility 69:1092-1094.
  95. Augé N, Santanam N, Parthasarathy S. 1998. An efficient method for solubilizing ß-carotene in aqueous solutions. J Medicinal Food 1:39-43.
  96. Murphy AA, Santanam N, Morales AJ, Parthasarathy S.  1998. Lysophosphatidyl choline, a chemotactic factor for monocytes/T-lymphocytes is elevated in endometriosis. J Clin Endo and Metabolism 83:2110-2113.
  97. Murphy AA, Palinski W, Rankin S, Morales AJ, Parthasarathy S. 1998. Macrophage scavenger receptor(s) and oxidatively-modified proteins in endometriosis. Fertility and Sterility 69:1085-1091.
  98. Rayner BD, Parthasarathy S. 1998. Vascular cell adhesion molecule in pregnancy.  Am J Obstet Gynecol 197:279.
  99. Fukai T, Galis ZS, Meng XP, Parthasarathy S, Harrison DG. 1998. Vascular expression of ecSOD in atherosclerosis. J Clin Invest 101:2101-2111.
  100. Shern-Brewer R, Santanam N, Wetzstein C, White-Welkley J, Parthasarathy S. 1998. Exercise and cardiovascular disease – a new perspective.  Arteriosclerosis, Thrombosis, & Vascular Biology 18:1181-1187.
  101. Fu W, Luo H, Parthasarathy S, Mattson MP. 1998. Catecholamines Potentiate Amyloid β-Peptide Neurotoxicity: Involvement of Oxidative Stress, Mitochondrial Dysfunction, and Perturbed Calcium Homeostasis. Neurobiology of Disease 5:229-243.
  102. Santanam N, Shern-Brewer R, McClatchey R, Castellano PZ, Murphy AA, Voelkel S, Parthasarathy S. 1998. Estradiol as an antioxidant: incompatible with its physiological concentrations and function. J Lipid Research. 39:2111-2118.
  103. Roberts CP, Murphy AA, Santanam N, Parthasarathy S. 1998. Regulation of monocyte to macrophage differentiation by antiglucocorticoids and antioxidants. Am J Obstet Gynecol 179: 354-362.
  104. Bruce-Keller AJ, Geddes JW, Knapp PE, McFall RW, Keller, Holtsberg FW, Parthasarathy S, Steiner SM, Mattson MP. 1998. Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD.  J of Neuroimmunology 93:53-71.
  105. Augé N, Keshava C, Santanam N, Parthasarathy S. 1999. Uptake of 13-Hydroperoxylinoleic  acids by cultured cells.  Arteriosclerosis, Thrombosis, & Vascular Biology 19:925-931.
  106. Shanti A, Santanam N, Morales AJ, Parthasarathy S, Murphy AA. 1999. Autoantibodies to markers of oxidative stress are elevated in women with endometriosis. Fertility and Sterility 71(6):1115-1118.
  107. Kim JG, Taylor WR, Parthasarathy S. 1999. The use of a novel antibody to demonstrate the presence of lipid peroxide-modified proteins in human atherosclerotic lesion. Atherosclerosis 143:335-340.
  108. Ferguson, E, Hogg, N, Antholine, W.E., Joseph, J., Singh, R.J., Parthasarathy, S., and Kalyanaraman, B. 1999. Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: Antioxidant implications. Free Radical Biology & Medicine 26: 968-977.
  109. Ramasamy S, Drummond, G.R., Ahn J, Storek M, Pohl J, Parthasarathy S, Harrison DG. 1999. Modulation of Expression of Endothelial Nitric Oxide Synthase by Nordihydroguaiaretic acid, a Phenolic Antioxidants in Cultured Endothelial Cells.  Mol. Pharmacol. 56: 116-123.
  110. Augé, N., Nilolava-Karakashian, N., Carpentier, S., Parthasarathy, S., Negre-Salvayre, A., Salvayre, R., Merrill, A.H., and Levade, T. (1999) Role of Sphingosine-1-phosphate in Mitogenesis Induced by Oxidized Low Density Lipoprotein in Smooth Muscle Cells via Activation of Sphingomyelinase, Ceramidase, and Sphingosine Kinase. J. Biol. Chem. 274: 21533-21538.
  111. Santanam, N., Augé, N, Zhou, M., Keshava, C., and Parthasarathy, S. (1999) Overexpression of Human Catalase Gene Decreases Oxidized Lipid-Induced Cytotoxicity in Vascular Smooth Muscle Cells. Arterioscler. Thromb. Vasc. Biol. 19: 1912-1917.
  112. Santanam, N., Jonas, C., Murphy, A.A., and Parthasarathy, S. (1999) Vitamin E Supplementation Decreases Autoantibodies to Oxidized Lipid-Protein Complexes. J. Med. Food. 1: 247-251.
  113. O’Donnell, V., Taylor K., Parthasarathy, S., Kuhn, H., Koesling, D., Friebe, A., Bloodsworth, A., Darley-Usmar, V., and Freeman, B. (1999) 15-Lipoxygenase Catalytically Consumes Nitric Oxide and Impairs Activation of Guanylate Cyclase. J. Biol. Chem. 274: 20083-20091.
  114. Kim, J. G., Ramachandran, S., Zhou, H. M., Rayner, D., and Parthasarathy, S. (2000) Implications in the maintenance of pregnancy:  I.  Presence of immunoreactive glycodelin in human umbilical cord vein endothelial cells.  Fertility and Sterility 73: 839-842.
  115. Zhou, H. M., Ramachandran, S., Kim, J. G., Raynor, D. B., Rock, J. A., and Parthasarathy, S. (2000) Implications in the management of pregnancy:  II.  Low levels of gene expression but enhanced uptake and accumulation of umbilical cord glycodelin.  Fertility and Sterility 73: 843-847.
  116. Meilhac, O., Zhou, M, Santanam, N., and Parthasarathy, S. (2000) Lipid Peroxides induce expression of catalase in cultured vascular cells.  Journal of Lipid Research 41: 1205-1213.
  117. Penumetcha, M., Khan, N., and Parthasarathy, S. (2000) Dietary oxidized fatty acids:  an atherogenic risk?  Journal of Lipid Research 41: 1473-1480.
  118. Kim, J.G., Santanam, N., and Parthasarathy, S. (2000) A Novel Antibody to Oxidized Phosphatidylethanolamine That Is Specific for Amino Groups Modified by Lipid Peroxides.  Journal of Medicinal Food 3, 129.
  119. Murphy, A. A., Zhou, M. H., Malkapuram, S., Santanam, N., Parthasarathy, S., and Sidell, N. (2000) RU486-induced growth inhibition of human endometrial cells.  Fertility and Sterility 74, 1014-1019.
  120. Navalkar, S., Parthasarathy, S., Santanam, N., and Khan, B. V. (2001) Irbesartan, an angiotensin type 1 inhibitor, regulates markers of inflammation in patients with premature atherosclerosis.  Journal of the American College of Cardiology 37, 440-444.
  121. Arnold, R. S., Shi, J., Murad, E., Whalen, A. M., Sun, C. Q., Polavarapu, R., Parthasarathy, S., Petros, J. A., Lambeth, J. D., (2001) Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1.  Proceedings of the National Academy of Sciences of the United States of America 98 (10): 5550-5555.
  122. Ramachandran, S., Song, M., Murphy, AA, and Parthasarathy, S. (2001) Expression of Scavenger Receptor Class B1 in Endometrium and Endometriosis.  The Journal of Clinical Endocrinology & Metabolism 86: 3924-3928.
  123. Song, M., Ramaswamy, S., Ramachandran, S., Flowers, LC, Horowitz, IR, Rock, JA, and Parthasarathy, S. (2001) Angiogenic role for glycodelin in tumorigenesis.  Proceedings of the National Academy of Sciences of the United States of America 98: 92-9270.
  124. Horowitz, IR, Cho, C., Song, M., Flowers, LC, Santanam, N., Parthasarathy, S., and Ramachandran, S. (2001) Increased glycodelin levels in gynecological malignancies. Int J Gynecol Cancer 11: 173-179.
  125. Meilhac, O., Ramachandran, S., Chiang, K., Santanam N., Parthasarathy, S. (2001) Role of arterial wall antioxidant defense in beneficial effects of exercise on atherosclerosis in mice. Arterioscler Thromb Vasc Biol.21: 1681-1688.
  126. Gill, K., Kirma, N., Gunna, S.V., Santanam, N., Parthasarathy, S., Tekmal R. R. (2001) Regulation of colony stimulating factor-1 in endometrial cells: glucocorticoids and oxidative stress regulate the expression of CSF-1 and its receptor c-fms in endometrial cells. 76(5):1005-1011. 
  127. Khan, B.V., Navalkar, S., Khan, Q., Rahman, S., Parthasarathy, S. (2001) Irbesartan, an Angiotensin Type 1  receptor inhibitor, Regulates the Vascular Oxidative State in Patients with Coronary Artery Disease.  Journal of the American College of Cardiology, 38 (6): 1662-1667.
  128. Escarguel-Blanc, I., Salvayre, R., Vacaresse, N., Jurgens, G., Darblade, B., Arnal, J., Parthasarathy, S.,       Negre-Salvayre, A.  (2001).  Mildly Oxidized LDL Induces Activation of Platelet-Derived Growth factor B-Receptor Pathway.  Basic Science Reports, 1814-1821.
  129. Levonen AL1, Patel RP, Brookes P, Go YM, Jo H, Parthasarathy S, Anderson PG, Darley-Usmar VM. Mechanisms of cell signaling by nitric oxide and peroxynitrite: from mitochondria to MAP kinases.  ntioxid Redox Signal. 2001 Apr;3(2):215-29
  130. Ramachandran, S.,  Ramaswamy, S., Cho, C. Parthasarathy, S.  (2002).  Lysophospatidic acid induces glycodelin gene expression in cancer cells.  Cancer Letters, 177: 197-202. 
  131. Rong R.,  Ramachandran, S., Penumetcha, M., Khan, N., Parthasarathy, S.,   (2002) Dietary oxidized fatty acids may enhance intestianl apolipoprotein A-I production.  Journal of Lipid Research, 43:557-564.
  132. Penumetcha, M., Khan-Merchant, N. and Parthasarathy, S. (2002).  Enhanced Solubilization and Intestinal absorption of Cholesterol by Oxidized Linoleic Acid.  Journal of Lipid Research, 43: 895-903.
  133. Rong, R., Ramachandran, S., Santanam, N., Murphy, AA., Parthasarathy, S., (2002).  Induction of Monocyte Chemotactic Protein-1 in peritoneal mesothelial and endometrial cells , by Oxidized LDL and Peritoneal Fluid from Endometriosis Subjects. Fertility Sterility, Feb; 77 Suppl.1: 814-815
  134. Ramachandran, A, Moellering, D. Go, Y., Shiva, S., Levoneo, A., Jo, H., Patel, R., Parthasarthy, S., Darley-Usmar, V.  (2002) Activation of C-Jun N-Terminal Kinase and Apoptosis in Endothelial Cells Mediated by Endogenous Generation of Hydrogen Peroxide.  J. Bio. Chem., Vol. 383: 693-701.
  135. Rahman ST, Lauten WB, Khan QA, Navalkar S, Parthasarathy S, Khan BV. Effects of eprosartan versus hydrochlorothiazide on markers of vascular oxidation and inflammation and blood pressure (renin-angiotensin system antagonists, oxidation, and inflammation). Am J Cardiol. 2002 Mar 15;89(6):686-90.
  136. Richlin, S.S., Ramachandran, S., Shanti, A., Murphy, A.A. and Parthasarathy, S. (2002) Glycodelin levels in uterine flushings and in plasma of patients with leiomyomas and polyps: implications for implantation. Human Reproduction, 17: 2742-2747.
  137. Lin, Y., Huang, R., Santanam, S., Liu, Y., Parthasarathy, S., and Huang R. P. (2002) Profiling of human cytokines in healthy individuals with Vitamin E supplementation by antibody array. Cancer Lett. 187: 17-24.
  138. Meng, C.Q., Somers, P.K., Rachita, C.L., Holt, L.A., Hoong, L.K., Zheng, X.S., Simpson, J.E., Hill, R.R., Olliff, L.K., Kunsch, C., Sundell, C.L., Parthasarathy, S., Saxena, U., Sikorski, J.A. and Wasserman, M.A. (2002) Novel phenolic antioxidants as multifunctional inhibitor if inducible VCAM-1 expression for use in atherosclerosis. Bioorg. Med. Chem. Lett. 12: 2545-2548.
  139. Khan-Merchant N. Penumetcha M. Meilhac O. Parthasarathy S. (2002) Oxidized fatty acids promote atherosclerosis only in the presence of dietary cholesterol in low-density lipoprotein receptor knockout mice. Journal of Nutrition. 132(11):3256-62.
  140. Hink HU. Santanam N. Dikalov S. McCann L. Nguyen AD. Parthasarathy S. Harrison DG. Fukai T. (2002) Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity. Arteriosclerosis, Thrombosis & Vascular Biology. 22(9):1402-.
  141. Song M. Karabina SA. Kavtaradze N. Murphy AA. Parthasarathy S. (2003) Presence of endometrial epithelial cells in the peritoneal cavity and the mesothelial inflammatory response. Fertility & Sterility. 79:789-94.
  142. Ramachandran S. Rong R. Parthasarathy S. (2003) Oxidants and antioxidants affect the expression of glycodelin. Free Radical Biology & Medicine. 34:818-23.
  143. Narsipur1, S.S. Peterson, O.W., Smith, R., Bigby, T.D., Parthasarathy, S. , Gabbai, F.B., Wilson, C.B., and Blantz, R.C. (2003) The mechanisms of glomerular immune injury: effects of antioxidant treatment. J. Am. Soc. Nephrol. J.Am.Soc. Nephrol.  14:1748-55.
  144. Lauten WB, Khan QA, Rajagopalan S, Lerakis S, Rahman ST, Parthasarathy S, Khan BV. (2003) Usefulness of quinapril and irbesartan to improve the anti-inflammatory response of atorvastatin and aspirin in patients with coronary heart disease. Am J Cardiol 91:1116-9.
  145. Santanam, N., Penumetcha, M., Speisky, H., and Parthasarathy, S. (2004) A novel alkaloid antioxidant, Boldine and synthetic antioxidant, reduced form of RU 486 inhibit the oxidation of LDL in-vitro and atherosclerosis in vivo in LDLR-/- mice. Atherosclerosis 173: 203-210.
  146. Xuan Cao, DongZi Yang,  MingQing Song, Ana Murphy, Sampath Parthasarathy. (2004)The Presence of Endometrial Cells in the Peritoneal Cavity Enhances Monocyte Recruitment and Induces Inflammatory Cytokines in Mice. Implications in Endometriosis. Fertility & Sterility 82: 999-1007.
  147. Chiang, K., Parthasarathy, S. and Santanam, N. (2004) Estrogen, neutrophils and Oxidation. Life Sciences 75, 2425-2438.
  148. Huang R. Lin Y. Shi Q. Flowers L. Ramachandran S. Horowitz IR. Parthasarathy S. Huang RP. Enhanced protein profiling arrays with ELISA-based amplification for high-throughput molecular changes of tumor patients' plasma. Clinical Cancer Research. 10(2):598-609, 2004 Jan 15.
  149. Sola S, Mir MQ, Cheema FA, Khan-Merchant N, Menon RG, Parthasarathy S, Khan BV. Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study. Circulation. 2005 Jan 25;111(3):343-8.
  150. Ramachandran S. Penumetcha M. Merchant NK. Santanam N. Rong R. Parthasarathy S. Exercise reduces preexisting atherosclerotic lesions in LDL receptor knock out mice. Atherosclerosis. 178(1):33-8, 2005 Jan.
  151. Houston M. Julien MA. Parthasarathy S. Chaikof EL. Oxidized linoleic acid regulates expression and shedding of syndecan-4. American Journal of Physiology - Cell Physiology. 288(2):C458-66, 2005 Feb.
  152. Higashi Y, Peng T, Du J, Sukhanov S, Li Y, Itabe H, Parthasarathy S, Delafontaine P. A redox-sensitive pathway mediates oxidized LDL-induced down regulation of insulin-like growth factor-1 receptor. J Lipid Res. 2005 Jun; 46(6):1266-77.
  153. Ramachandran S. Song MQ. Lowe E. Dominguez CE. Parthasarathy S. Murphy AA. RU486 inhibits expression of lysophosphatidic acid induced glycodelin. American Journal of Obstetrics & Gynecology. 192:1285-93; 1293-4, 2005 Apr.
  154. Wei C, Penumetcha M, Santanam N, Liu YG, Garelnabi M, Parthasarathy S. (2005) Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects. Biochim Biophys Acta. 1723: 124-127.
  155. Karabina SA, Lehner AN, Frank E, Parthasarathy S, Santanam N. (2005) Oxidative inactivation of paraoxonase--implications in diabetes mellitus and atherosclerosis.  Biochim Biophys Acta. 1725:213-21.
  156. Sukhanov S, Higashi Y, Shai SY, Itabe H, Ono K, Parthasarathy S, Delafontaine P. Novel effect of oxidized low-density lipoprotein: cellular ATP depletion via downregulation of glyceraldehyde-3-phosphate dehydrogenase.Circ Res. 2006 Jul 21;99(2):191-200.
  157. Santanam N, Parthasarathy S. Aspirin is a substrate for paraoxonase-like activity: Implications in atherosclerosis. Atherosclerosis. 2006 Jun 19.
  158. Park JK, Song M, Dominguez CE, Walter MF, Santanam N, Parthasarathy S, Murphy AA. Glycodelin mediates the increase in vascular endothelial growth factor in response to oxidative stress in the endometrium.Am J Obstet Gynecol. 2006 Dec; 195(6):1772-7.
  159. Bhaskaran S, Santanam N, Penumetcha M, Parthasarathy S. Inhibition of atherosclerosis in low-density lipoprotein receptor-negative mice by sesame oil. J Med Food. 2006;9 (4):487-90.
  160. Joshi MS, Ferguson TB Jr, Johnson FK, Johnson RA, Parthasarathy S, Lancaster JR Jr. Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells. Proc Natl Acad Sci U S A. 2007 Jun 12; 104(24):9982-7. Epub 2007 May 29.
  161. Garelnabi M, Selvarajan K, Litvinov D, Santanam N, Parthasarathy S. Dietary oxidized linoleic acid lowers triglycerides via APOA5/APOClll dependent mechanisms. Atherosclerosis. 2008 Aug; 199(2) :304-9
  162. Jaichander, P., Selvarajan, K., Garelnabi, M., and Parthasarathy, S. Induction of paraoxonase 1 and apolipoprotein A1 gene expression by aspirin. J. Lipid Res. Vol. 49, 2142-2148, October 2008
  163. Steinhour E, Sherwani SI, Mazerik JN, Ciapala V, O'Connor Butler E, Cruff JP, Magalang U, Parthasarathy S, Sen CK, Marsh CB, Kuppusamy P, Parinandi NL. Redox-active antioxidant modulation of lipid signaling in vascular endothelial cells: vitamin C induces activation of phospholipase D through phospholipase A(2), lipoxygenase, and cyclooxygenase. Mol Cell Biochem. 2008 Aug;315(1-2):97-112. Epub 2008 May 22
  164. Maiseyeu A, Mihai G, Kampfrath T, Simonetti OP, Sen CK, Roy S, Rajagopalan S, Parthasarathy S. Gadolinium containing phosphatidylserine liposomes for molecular imaging of atherosclerosis. J Lipid Res. 2009, Nov;50(11):2157-63. 
  165. Higashi Y, Sukhanov S, Parthasarathy S, Delafontaine P. The ubiquitin ligase Nedd4 mediates oxidized low-density lipoprotein-induced downregulation of insulin-like growth factor-1 receptor. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1684-9. Epub 2008 Aug 22.
  166. Raghavamenon A, Garelnabi M, Babu S, Aldrich A, Litvinov D, Parthasarathy S. Alpha-tocopherol is ineffective in preventing the decomposition of preformed lipid peroxides and may promote the accumulation of toxic aldehydes: a potential explanation for the failure of antioxidants to affect human atherosclerosis. Antioxid Redox Signal. 2009 Jun;11(6):1237-48. PubMed PMID: 19186999; PubMed Central PMCID: PMC2842134.
  167. Sun Q, Yue P, Deiuliis JA, Lumeng CN, Kampfrath T, Mikolaj MB, Cai Y, Ostrowski MC, Lu B, Parthasarathy S, Brook RD, Moffatt-Bruce SD, Chen LC, Rajagopalan S. Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity. Circulation. 2009 Feb 3;119(4):538-46. Epub 2009 Jan 19.
  168. Ying Z, Kherada N, Farrar B, Kampfrath T, Chung Y, Simonetti O, Deiuliis J, Desikan R, Khan B, Villamena F, Sun Q, Parthasarathy S, Rajagopalan S. Lipoic acid effects on established atherosclerosis. Life Sci. 2010 Jan 16;86(3-4):95-102. Epub 2009 Nov 26. PubMed PMID: 19944706.
  169. Litvinov D, Selvarajan K, Garelnabi M, Brophy L, Parthasarathy S. Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. Atherosclerosis. 2010 Apr;209(2):449-54. Epub 2009 Oct 12. PubMed PMID: 19880116; PubMed Central PMCID: PMC2846213
  170. Garelnabi M, Veledar E, Abramson J, White-Welkley J, Santanam N, Weintraub W, Parthasarathy S. Physical inactivity and cardiovascular risk: baseline observations from men and premenopausal women. J Clin Lab Anal. 2010 Mar;24(2):100-5. PubMed PMID: 20333763.
  171. Kwiatkowski P, Sai-Sudhakar C, Philips A, Parthasarathy S, Sun B. Development of a novel large animal model of ischemic heart failure using autologous platelet aggregates. Int J Artif Organs. 2010 Feb;33(2):63-71. PubMed PMID: 20306432.
  172. Parthasarathy S. Lipolysis needed for chylomicron uptake? Arterioscler Thromb Vasc Biol. 2010 Jan;30(1):5-6. PubMed PMID: 20018939.
  173. Ying Z, Kampfrath T, Sun Q, Parthasarathy S, Rajagopalan S. Evidence that α-lipoic acid inhibits NF-κB activation independent of its antioxidant function. Inflamm Res. 2010 Oct 7. [Epub ahead of print] PMID: 20927568
  174. Lu T, Parthasarathy S, Hao H, Luo M, Ahmed S, Zhu J, Luo S, Kuppusamy P, Sen CK, Verfaillie CM, Tian J, Liu Z. Reactive Oxygen Species Mediate Oxidized Low-Density Lipoprotein-Induced Inhibition of Oct-4 Expression and Endothelial Differentiation of Bone Marrow Stem Cells. Antioxid Redox Signal. 2010 Oct 12.
  175. Mahdi Garelnabi, Litvinov Dmitry, Parthasarathy Sampath. Evaluation of a gas chromatography method for azelaic acid determination in selected biological samples. North Am J Med Sci; 2: 397-402, 2010
  176. Maiseyeu A, Mihai G, Roy S, Kherada N, Simonetti OP, Sen CK, Sun Q, Parthasarathy S, Rajagopalan S. Detection of macrophages via paramagnetic vesicles incorporating oxidatively tailored cholesterol ester: an approach for atherosclerosis imaging. Nanomedicine (Lond). 2010 Nov;5(9):1341-56.PMID: 21128718
  177. Kampfrath T, Maiseyeu A, Ying Z, Shah Z, Deiuliis JA, Xu X, Kherada N, Brook RD, Reddy KM, Padture NP, Parthasarathy S, Chen LC, Moffatt-Bruce S, Sun Q, Morawietz H, Rajagopalan S. Chronic Fine Particulate Matter Exposure Induces Systemic Vascular Dysfunction via NADPH Oxidase and TLR4 Pathways Circ Res. 2011 Jan 27. [Epub ahead of print] PMID: 21273555 [PubMed - as supplied by publisher].
  178. Gaillard T, Parthasarathy S, Osei K. HDL dysfunctionality (Paraoxonase) is worse in nondiabetic, postmenopausal African American than in white women. Diabetes Care. 2011 Feb;34(2):e19. PMID: 21270177
  179. Penumetcha M, Merchant N, Parthasarathy S. Modulation of Leptin Levels by Oxidized Linoleic Acid: A Connection to Atherosclerosis? J Med Food. 2010 Dec 27. PMID: 21186986
  180. Ying Z, Kherada N, Kampfrath T, Mihai G, Simonetti O, Desikan R, Selvendiran K, Sun Q, Ziouzenkova O, Parthasarathy S, Rajagopalan S. A modified sesamol derivative inhibits progression of atherosclerosis. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):536-42. Epub 2010 Dec 23. PMID: 21183734 
  181. Chandrakala AN, Sukul D, Selvarajan K, Sai-Sudhakar C, Sun B, Parthasarathy S. Induction of Brain Natriuretic Peptide and Monocyte Chemotactic Protein1 Gene Expressions by Oxidized Lowdensity Lipoprotein-Relevance to Ischemic Heart Failure.  Am J Physiol Cell Physiol. 2011 Sep 7. [Epub ahead of print] PMID: 21900689 [PubMed - as supplied by publisher]
  182. Garelnabi M, Veledar E, White-Welkley J, Santanam N, Abramson J, Weintraub W, Parthasarathy S. Vitamin E differentially affects short term exercise induced changes in oxidative stress, lipids, and inflammatory markers. Nutr Metab Cardiovasc Dis. 2011 Jul 20. [Epub ahead of print] PMID: 21782401 [PubMed - as supplied by publisher]
  183. Xu X, Ying Z, Cai M, Xu Z, Li Y, Jiang SY, Tzan K, Wang A, Parthasarathy S, He G, Rajagopalan S, Sun Q. Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue. Am J Physiol Regul Integr Comp Physiol. 2011 May;300(5):R1115-25. Epub 2011 Mar 2. PMID: 21368268 [PubMed - indexed for MEDLINE]
  184. Selvarajan K, Moldovan L, Chandrakala AN, Litvinov D, Parthasarathy S. Peritoneal macrophages are distinct from monocytes and adherent macrophages. Atherosclerosis. 219: 475-483, 2011
  185. Penumetcha M, Song M, Merchant N, Parthasarathy S. Pretreatment with n-6 PUFA protects against subsequent high fat diet induced atherosclerosis-Potential role of oxidative stress-induced antioxidant defense. Atherosclerosis. 2012 Jan;220(1):53-8. Epub 2011 Oct 12. PMID: 22035574 [PubMed - in process]
  186. Maiseyeu A, Badgeley MA, Kampfrath T, Mihai G, Deiuliis JA, Liu C, Sun Q, Parthasarathy S, Simon DI, Croce K, Rajagopalan S. In Vivo Targeting of Inflammation-Associated Myeloid-Related Protein 8/14 Via Gadolinium Immunonanoparticles. Arterioscler Thromb Vasc Biol. 2012 Feb 2. [Epub ahead of print] PMID: 22308043 [PubMed - as supplied by publisher]
  187. Kannan Y, Sundaram K, Narasimhulu CA, Parthasarathy S, Wewers MD. Oxidatively modified LDL inhibits TLR2 and TLR4 responses in human monocytes but not in macrophages. J Biol Chem. 2012 Jul 6;287(28):23479-88 [Epub ahead of print] PMID: 22613713
  188. Ying Z, Desikan R, Xu X, Maiseyeu A, Liu C, Sun Q, Ziouzenkova O, Parthasarathy S, Rajagopalan S. Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression. J Lipid Res. 2012 May;53(5):879-87. Epub 2012 Feb 21. PMID: 22355094
  189. Santanam N, Kavtaradze N, Murphy A, Dominguez C, Parthasarathy S. Antioxidant supplementation reduces endometriosis-related pelvic pain in humans. Transl Res. 2013 Mar;161(3):189-95. doi: 10.1016/j.trsl.2012.05.001. Epub 2012 May 31. PMID: 22728166 [PubMed - indexed for MEDLINE]
  190. Rocher C, Singla R, Singal PK, Parthasarathy S, Singla DK. Bone morphogenetic protein 7 polarizes THP-1 cells into M2 macrophages. Can J Physiol Pharmacol. 2012 Jul;90(7):947-51. Epub 2012 Jun 21. PMID: 22720873 [PubMed - in process]
  191. Merino H, Parthasarathy S, Singla DK. Partial ligation-induced carotid artery occlusion induces leukocyte recruitment and lipid accumulation-A shear stress model of atherosclerosis. Mol Cell Biochem. 2013 Jan;372(1-2):267-73. PubMed PMID: 23054191.
  192. Liu C, Desikan R, Ying Z, Gushchina L, Kampfrath T, Deiuliis J, Wang A, Xu X, Zhong J, Rao X, Sun Q, Maiseyeu A, Parthasarathy S, Rajagopalan S. Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model. PLoS One. 2012;7(12):e50767. doi: 10.1371/journal.pone.0050767. Epub 2012 Dec 10.
  193. Kamble P, Selvarajan K, Aluganti Narasimhulu C, Nandave M, Parthasarathy S. Aspirin may promote mitochondrial biogenesis via the production of hydrogen peroxide and the induction of Sirtuin1/PGC-1α genes. Eur J Pharmacol. 2013 Jan 15;699(1-3):55-61. doi: 10.1016/j.ejphar.2012.11.051. Epub 2012 Dec 7.
  194. Sengupta B, Narasimhulu CA, Parthasarathy S. Novel technique for generating macrophage foam cells for in vitro reverse cholesterol transport studies. J Lipid Res. 2013 Dec; 54(12):3358-72. doi: 10.1194/jlr.M041327. Epub 2013 Oct 9. PMID: 24115226 [PubMed - in process]
  195. Spata T, Bobek D, Whitson BA, Parthasarathy S, Mohler PJ, Higgins RS, Kilic A. A nonthoracotomy myocardial infarction model in an ovine using autologous platelets. Biomed Res Int. 2013; 2013:938047
  196. Chandrakala AN, Kwiatkowski P, Sai-Sudhakar CB, Sun B, Phillips A, Parthasarathy S. Induction of early biomarkers in a thrombus-induced sheep model of ischemic heart failure. Tex Heart Inst J. 2013; 40(5):511-20. PMID: 24391310 [PubMed - in process]
  197. Hossain T, Riad A, Siddiqi S, Parthasarathy S, Siddiqi SA. Mature VLDL triggers the biogenesis of a distinct vesicle from the trans-Golgi network for its export to the plasma membrane. Biochem J. 2014 Apr 1; 459(1): 47-58. doi: 10.1042/BJ20131215. PMID: 24433144.
  198. Aluganti Narasimhulu C, Selvarajan K, Brown M, Parthasarathy S. Cationic peptides neutralize Ox-LDL, prevent its uptake by macrophages, and attenuate inflammatory response. Atherosclerosis. 2014 Sep; 236(1):133-41.
  199. Li X1, Xiao Y, Cui Y, Tan T, Narasimhulu CA, Hao H, Liu L, Zhang J, He G, Verfaillie CM, Lei M, Parthasarathy S, Ma J, Zhu H, Liu Z. Cell membrane damage is involved in the impaired survival of bone marrow stem cells by oxidized low-density lipoprotein. J Cell Mol Med. 2014 Sep 25. doi: 10.1111/jcmm.12424. [Epub ahead of print]
  200. Narasimhulu CA, Selvarajan K, Litvinov D, Parthaarathy S. Anti-atherosclerotic and anti-inflammatory actions of sesame oil.  J Med Food. 2015 Jan;18(1):11-20.
  201. Selvarajan K, Narasimhulu CA, Bapputty R, Parthasarathy S. Anti-Inflammatory and Antioxidant Activities of the Nonlipid (Aqueous) Components of Sesame Oil: Potential Use in Atherosclerosis. J Med Food. 2015 Feb 18.
  202. Kamble P, Litvinov D, Aluganti Narasimhulu C, Jiang X, Parthasarathy S. Aspirin may influence cellular energy status. Eur J Pharmacol. 2015 Feb 15;749:12-9.
  203. Cui Y, Narasimhulu CA, Liu L, Li X, Xiao Y, Zhang J, Xie X, Hao H, Liu JZ, He G, Cowan PJ, Cui L, Zhu H, Parthasarathy S, Liu Z. Oxidized low-density lipoprotein alters endothelial progenitor cell populations. Front Biosci (Landmark Ed). 2015 Jun 1;20:975-88.
  204. Cui Y, Narasimhulu CA, Liu L, Zhang Q, Liu PZ, Li X, Xiao Y, Zhang J, Hao H, Xie X, He G, Cui L, Parthasarathy S, Liu Z. N-acetylcysteine inhibits in vivo oxidation of native low-density lipoprotein. Sci Rep. 2015 Nov 5; 5:16339. doi: 10.1038/srep16339. PMID: 26536834
  205. Fernandez-Ruiz I, Puchalska P, Aluganti Narasimhulu C, Sengupta B, Parthasarathy S. Differential lipid metabolism in monocytes and macrophages-influence of cholesterol loading. J Lipid Res. 2016 Feb 2. pii: jlr.M062752. [Epub ahead of print] PMID: 26839333 [
  206. Aluganti Narasimhulu C, Litvinov D, Sengupta B, Jones D, Sai-Sudhakar C, Firstenberg M, Sun B, Parthasarathy S. Increased presence of oxidized low-density lipoprotein in the left ventricular blood of subjects with cardiovascular disease. Physiol Rep. 2016 Mar;4(6). pii: e12726. doi: 10.14814/phy2.12726. Epub 2016 Mar 31. PMID: 27033448 [PubMed]
  207. Zhang Q, Chen L, Si Z, Bu H, Narasimhulu CA, Song X, Cui MY, Liu H, Lu T, He G, Parthasarathy S, Cui L, Liu Z, Cui Y. Probucol Protects Endothelial Progenitor Cells Against Oxidized Low-Density Lipoprotein via Suppression of Reactive Oxygen Species Formation In Vivo. Cell Physiol Biochem. 2016;39(1):89-101. doi: 10.1159/000445608. Epub 2016 Jun 20. PMID: 27322674 [PubMed - in process]
  208. Narasimhulu CA, Selvarajan K, Burge KY, Litvinov D, Sengupta B, Parthasarathy S. Water-Soluble Components of Sesame Oil Reduce Inflammation and Atherosclerosis. J Med Food. 2016 Jun 27. [Epub ahead of print] PMID: 27348418 [PubMed - as supplied by publisher]
  209. Santanam N, Zoneraich N, Parthasarathy S. Myeloperoxidase as a Potential Target in Women With Endometriosis Undergoing IVF. Reprod Sci. 2016 Sep 22. pii:1933719116667225. [Epub ahead of print PMID: 27662901
  210. Narasimhulu CA, Nandave M, Bonilla D, Singaravelu J, Sai-Sudhakar CB and Parthasarathy S. Circulating platelet aggregates damage endothelial cells in culture journal of surgical research (cover page article) 2017; 213:90-99. 
  211. Mordhwaj P, Litvinov D, Babu S, Chandrakala A and Parthasarathy S. Potential Role of Mitochondrial Dysfunction in Diabetic Hypertriglyceridemia JETR 2017; 2(1): 555579. 
  212. Desikan R, Narasimhulu CA, Khan B, Rajagopalan S, and Parthasarathy S. Myeloperoxidase (MPO): Do We Need Inhibitors? Advances in Biochemistry in Health and Disease-Mechanisms of Vascular Defects in Diabetes Mellitus. 2017; 535-571.

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