Ayman I Sayegh, DVM, PhD, FTOS
Professor of Biomedical Sciences

Associate Dean for Research and Advanced Studies
College of Veterinary Medicine
Tuskegee University, Tuskegee, Alabama, USA
Phone: 334 727 8149
Email id: sayeghai@mytu.tuskegee.edu
Fax: 334 724 4672


Institution and Location Degree
(if applicable)
MM/YY Field of Study
Baghdad University, Iraq DVM 07/87 Veterinary Medicine
Kansas State University, KS MS 07/93 Master of Science
Purdue University, IN Training 08/95 Equine Med. and Surg.
University of Illinois, IL Internship 05/97 Surgical Internship
Washington State University, WA PhD 11/00 Neuroscience


Dr. Sayegh is a Professor of Biomedical Sciences, College of Veterinary Medicine, Tuskegee University and Associate Dean for Research and Advanced Studies. He attended Baghdad University (Iraq, Veterinary Medicine), Kansas State University (MS), Purdue University (Equine Medicine and Surgery), University of Illinois at Urbana Champaign (Equine Medicine and Surgery) and Washington State University (PhD, Neuroscience). His research focuses on localizing the peripheral site(s) of action for gastrin releasing peptide (GRP) and cholecystokinin (CCK), which evoke reduction of meal size and prolongation of the intermeal interval, by delivering the peptides into specific regions in the gastrointestinal tract through (1) utilizing a microsurgical, intra-arterial catheterization technique, (2) analyzing the min-to-min behaviors that lead to feeding to determine meal sizes, intermeal interval and satiety ratio, (3) using a BioDAQ feeding system to record and analyze the feeding behavior of the rats in a freely-fed, undisturbed environment. In addition, we use immunohistochemical detection of neuronal markers and various surgical techniques e.g. vagotomy, sympathectomy and myotomy / myectomy to determine the possible neuronal pathways by which these peptide reduce meal size and prolong the intermeal interval. The work is funded by the NIH and various pharmaceutical companies.

Research Interest

Scientific Activities


2000-2005 Tuskegee University  Assistant Professor of Biomedical Sciences
2005-2010 Tuskegee University Associate Professor of Biomedical Sciences
2010-Present Tuskegee University Professor of Biomedical Sciences
2014-Present Tuskegee University  Head, Department of Biomedical Sciences

Other Experience and Professional Memberships

2000 Society for the Study of Ingestive Behavior
2000 American Physiological Society
2000 Society of Neuroscience
1999 Reviewer for various journals (e.g. AJP [Integrative, GI and Endocrine], Endocrinology, Brain Res, Regulatory Peptides, Peptides, Physiology and Behavior, J Neuroscience, Neuroscience Letters and others)


2012 Pfizer Award For Excellence in Research
2008 Faculty achievement award, Tuskegee University
2006 Excellence in Biomedical Research, Veterinary Biomedical Research Symposium
2006 United Negro College Fund for the Henry C. McBay Research Fellowship
2006 The Russell W. Brown Distinguished Scientist Research Award, Sigma Xi
2006 Outstanding Faculty Performance Award For Research, Tuskegee University
2003 Pfizer Award For Excellence in Research
2002 Outstanding Faculty Performance Award For Research, Tuskegee University
2000-Current Trained 14 graduate students, 24 veterinary students, and 13 full time research associates


  1. Washington, M. C., Aglan, A. H. & Sayegh, A. I. (2014). The stomach and/or upper duodenum contain sites of action that control meal size and intermeal interval length by exogenous rat gastrin releasing peptide. Peptides 55C, 41-46.
  2. Sayegh, A. I., Washington, M. C., Raboin, S. J., Aglan, A. H. & Reeve, J. J., Jr. (2014). CCK-58 prolongs the intermeal interval, whereas CCK-8 reduces this interval: Not all forms of cholecystokinin have equal bioactivity. Peptides.
  3. Washington, M. C., Salyer, S., Aglan, A. H. & Sayegh, A. I. (2014). Intravenous infusion of gastrin-releasing peptide-27 and bombesin in rats reveals differential effects on meal size and intermeal interval length. Peptides 51, 145-9.
  4. Sayegh, A. I. (2013). The role of cholecystokinin receptors in the short-term control of food intake. Prog Mol Biol Transl Sci 114, 277-316.
  5. Sayegh, A. I. (2013). The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci 114, 343-70.
  6. Wright, S. A., Washington, M. C., Garcia, C. & Sayegh, A. I. (2012). Gastrin releasing peptide-29 requires vagal and splanchnic neurons to evoke satiation and satiety. Peptides 33, 125-31.
  7. Hunt, J. V., Washington, M. C. & Sayegh, A. I. (2012). Exenatide and feeding: possible peripheral neuronal pathways. Peptides 33, 285-90.
  8. Washington, M. C. & Sayegh, A. I. (2011). Gastrin releasing peptides increase Fos-like immunoreactivity in the enteric nervous system and the dorsal vagal complex. Peptides 32, 1600-5.
  9. Washington, M. C., Coggeshall, J. & Sayegh, A. I. (2011). Cholecystokinin-33 inhibits meal size and prolongs the subsequent intermeal interval. Peptides 32, 971-7.
  10. Metcalf, S. A., Washington, M. C., Brown, T. A., Williams, C. S., Strader, A. D. & Sayegh, A. I. (2011). Ileal interposition attenuates the satiety responses evoked by cholecystokinin-8 and -33. Peptides 32, 1296-302.

Animal Science and Research Flyer