Publications

Peer Reviewed Journal Articles

1. Klassen, A., Grant, C., Tsangaris, E., Wickert, N., Brill, H., Barr, R., Samaan, M.C., Gorter, J. Validation of a Unique Scale to Measure Transition Readiness in Adolescents with Chronic Health Conditions. .Child: Care, Health and Development. 2014 Oct 28. doi: 10.1111/cch.12207 [Epub ahead of print].
2. Dennis,B., Samaan, M.C., Bawor,M., Paul,J., Plater,C., Pare,G., Worster,A., VArenbut,M., Daiter,J., Marsh,D., Desai,D., Thabane,L., Samaan,Z., Evaluation of Clinical and Inflammatory Profile in Opioid Addiction Patients with Comorbid Pain: Results from a Multi-Centre Investigation.
Neuropsychiatric Disease and Treatment. 2014:10, 2239-2247.
3. Bawor,M., Dennis,B., Samaan, M.C., Plater,.C,. Worster,A., Varenbut,.M,. Daiter,J., Marsh,D., Desai,D. Steiner,M, Anglin,R., Coote,M., Pare,G., Thabane,L. Samaan,Z. Methadone induces testosterone suppression in patients with opioid addiction. Scientific Reports 4, doi:10.1038/srep06189. Aug 2014.
4. Samaan,M.C., Valencia,M., Cheung,C., Wilk,B,. Lau.K.,Thabane,L., The Design, Implementation ads evaluation of Pediatric & Adolescent Type 2 diabetes Management Program in a Tertiary pediatric Center. Journal of Multidisciplinary Healthcare. 7: 321-331. Jul 2014.
5. Samaan,M.C. Prader Willi Syndrome: Genetics & Neurobehavioral phenotype-genotype correlations. Current Psychiatry Reviews 2014, Vol.10, Pages 153-166.
6. O'Neill,H.M., Galic,S., Lally,J.S., Thomas,M., Azizi,P., Fullerton,M.D., Smith,B.J., Pulinikunnil,T., Samaan,M.C., Ford,R., Jorgensen,S.B., Lynch,G.S., Dyck,J.R., Holloway,G.P., Hawke,T.J., VanDenderen,B.J.. (2014). AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice. epub ahead of print. Diabetologia. 57(8): 1693-702.
7. Samaan, M.C, Scheinemann, K., Burrow, S., Dillenburg, R., Barr, R. Wang, K. Valencia, M., Thabane, L. (2014). Recruitment feasibility to a cohort study to ascertain endocrine and metabolic health among survivors of childhood brain tumors: A report from the Canadian study of Determinants of Endometabolic Health in ChIlDrEn (CanDECIDE). BMJ Open. 4(6):e005295.
8. Samaan, M.C., Xia, J., Badhiwala, J. Mechanisms & drivers of type 2 diabetes in Children & Adolescents. British Journal of Medicine & Medical Research. Published, SCIENCEDOMAIN International 4(23): 4054-4064. 2014
9. Samaan,M.C., Marcinko,K., Fullerton,M., Khan,M.I., Ziafazeli,T., Steinberg,G. Chronic Endurance Interval Training In Obese Mice reduces Muscle Macrophage Inflammation Independently Of Weight Loss. Physiological. May 20, 2014.
10. Samaan, M.C. Management of Type 2 Diabetes in Children & Adolescents. The International Journal of Pediatrics Vol 2013.
11. Samaan,M.C., Obeid,J., Nguyen,T., Timmons,B. Chemokine C-C Ligand 2 is a potential biomarker of inflammation & Physical Fitness in Obese Children: A Cross-Sectional Study. BMC Pediatric 2013, 13:47.
12. Samaan MC, Alassaf A, Dellavedova J, Murthy T. Exercise-induced hypoglycemic hemiplegia in type 1 diabetes: A rare find with multiple potential causative mechanisms. Case Reports in Medicine.  Published 2011.  Online link to paper: http://www.hindawi.com/journals/crim/aip/529097/.
13. Aditya, I., Khan, M.I., Samaan, M.C. The effect of High Fat Diet on Muscle Inflammation in Obesity. Journal of In-Vitro Cell and Developmental Biology. DOI 10.1007/s11626-013-9606-4. May 2012.
14. Samaan, M.C. The macrophage at the intersection of immunity and metabolism in obesity. Diabetology & Metabolic Syndrome 2011: Oct 28;3(1):29.  Epub ahead of print: http://www.dmsjournal.com/content/3/1/29.
15. Yu J, Shi L, Wang H, Bilan PJ, Yao Z, Samaan MC, He Q, Klip A, Niu W. Conditioned Medium from Hypoxia-Treated Adipocytes Renders Muscle Cells Insulin Resistant. Eur J Cell Biol. (Epub ahead of print);Volume 90, Issue 12: 1000-1015. Dec 2011.
16. Phillip J. Bilan, Victor Samokhvalov, Alexandra Koshkina, Jonathan D. Schertzer, M. C. Samaan, Amir Klip. Direct and macrophage-mediated actions of fatty acids causing insulin resistance in muscle cells. Archives of Physiology & Biochemistry; 115(4): 176-90. Oct 2009.
17. Samaan M.C., Klip A. Obesity, insulin resistance, and type 2 diabetes: the muscle-fat connection. Endocrinology rounds- St. Michael’s Hospital, Toronto; 8 (7). Sep 2008.
18. Samaan M.C., Daneman D., Hamilton J. Fetal origins of type 2 diabetes. US Pediatrics; Volume 4 (I), p60-62. Jun 2008.
19. Samaan M. C., Casotto V., Cutini M., Ryan C.A. Physician’s and Nurse’s attitudes towards neonatal ethical decision-making in Ireland. Arch. Dis. Child. Fetal and Neonatal Ed. May 2008.
20. Samaan M. C., Brennan A., Fitzgerald H., Roche E.F., Hoey H. Maturity Onset Diabetes of the young type 3 (MODY 3). Irish Medical Journal. 2005.

Peer Reviewed Journal Abstracts

1. Samaan,M.C., Duckworth,J., Scheinemann,K. Children Surviving Brain Tumors Have High Rates of Obesity Independent of Puberty. Neuro-Oncology 14:i130,2012 QL27.
2. Samaan, M.C., Fink, L., Klip A. Macrophage Attract Other Immune Cells in Response to Obesogenic Environment. Canadian Journal of Diabetes.2011 Vol.35, Issue 3 Page 295.
3. Samaan M.C., Bilan P, Klip A. Immune metabolic interactions in obesity: some cells talk and others listen Canadian. Paediatric Endocrine Group Meeting Calgary Alberta. 2010.
4. Samaan M.C., Cole D, Sochett E, Palmert M. Novel mutation in CASR gene leading to Familial Isolated Hyperparathyroidism: not all genes are created equal. Canadian Paediatric Endocrine Group Meeting. Feb 2009.
5. Roche E. F., Brennan A., Fitzgerald H., Samaan M.C., Hoey H. The Role of Continuous Glucose Monitoring in Type 1 Diabetes. Abstract, Irish Journal of Medical Science. Volume 172 Issue 4 e5. 2003.
6. Samaan M.C., Watson B. Cystic Fibrosis: how are the parents coping with their shild’s illness? Abstract, Journal of Cystic Fibrosis. Vol 1, SuppI: S 168. 2002.

Abstracts

1. Pillon NJ, Fink L, Schertzer J, Tamrakar AK, Kelwalramani G, Samaan MC, Arane K, Bilan PJ, Klip A. Immune cells and skeletal muscle connect inflammation with insulin resistance. 2nd International Conference for Models of Human Diseases. University of Toronto, Faculty of Medicine.  June 28th, 2011.

Book Chapter

1. Samaan, M.C. Neuroendocrine & Metabolic Effects of Cancer Therapy. The Brain Tumor Foundation of Canada Parent’s Handbook. 2011.

Case Report

1. Samaan M.C., Murphy N., Costigan C. Profound hyperlipidemia due to concomitant diabetes and hypothyroidism. BMJ case reports. Mar 2010.

Web article

1. Samaan, M.C. Explaining the weight gain-diabetes connection in kids. TheSpec.com.  http://www.thespec.com/print/article/657527. Jan 19, 2012.

Accepted for Publication
Journal Abstract

1. Pillon NJ, Fink L, Schertzer J, Tamrakar AK, Kelwalramani G, Samaan MC, Arane K, Bilan PJ, Klip. A. Immune cells and skeletal muscle connect inflammation with insulin resistance. 2nd International Conference for Models of Human Diseases. University of Toronto, Faculty of Medicine.  June 28th, 2011.

Submitted for Publication
Journal Article

1. Samaan, M.C., Akhtar-Danesh, N.. (2014). The impact of age and race on longevity in pediatric astrocytic tumors: A population-based study. Pediatric Blood & Cancer, December 2014.
2. Samaan, M.C., Anand, S, Sharma, AM, Samjoo, I, Tarnopolsky, M. Sex differences in skeletal muscle Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) levels: A cross-sectional study. Scientific Reports, Accepted for publication, February 2015.
3. Samaan, M.C., Anand, S, Bonner, A, Beyene, J, Sharma, AM, Samjoo, I, Tarnopolsky, M. Differences in immune-fat-muscle crosstalk in South Asians & Europeans: A cross-sectional study. Scientific Reports, November 2014.