Research Interest
Optimization of topical, transdermal and transmucosal drug delivery; development of novel permeation models and computational modeling.
- Design and evaluation of novel dermal penetration enhancers and retardants & their structure-activity relationships.
- Design and testing of novel formulations for topical and transdermal drug delivery including creams, emulsions, gels and micro-and nano-carrier systems.
- Physical approaches to enhancing dermal drug delivery: iontophoresis, microneedles as well as formulation optimization.
- Visualization of drug transport pathways in skin using Raman, Fourier Transform Infra-Red spectroscopy, electron and confocal microscopy.
- Development of novel human tissue cultured skin equivalents for permeability testing.
- Computational approaches to predicting skin transport of drugs.
- Optimization of oral transmucosal and vaginal drug delivery.
- Pharmacokinetics and ADME studies in animals and humans.
- Biorelevant drug release/dissolution testing of pharmaceutical dosage forms.
- Design & development of oral edible drug-containing polymer films.