Biography

I have worked extensively with the gastrointestinal tract, especially the absorption of lipids.  Over the years, I have published extensively on the formation and secretion of chylomicrons and the process regulating it.  In 1986 (as a Vice-Chair) and 1990 (Chair), I was involved in organizing the FASEB Summer Conference on Intestinal Absorption of Lipids.  For the last 20 years, I have also worked extensively on apolipoprotein AIV and have published over seventy papers and numerous review and book chapters on the subject.  For this work, I was awarded the Distinguished Research prize from the American Physiological Society.  Over the years, our laboratory has pioneered a number of concepts and approaches to study intestinal fat absorption: 1) Separate pathways for the assembly of chylomicrons and very low density lipoproteins; 2) non-invasive approach to the study of intestinal fat absorption (a method that has been used to study fat absorption in both rodents and humans, Jandacek RJ, Heubi JE, Tso P. A novel, noninvasive method for the measurement of intestinal fat absorption.Gastroenterology.2004: 127:139-44); 3) a model for the simultaneous sampling of lymph and portal blood in rats; and 4) lymph fistula mouse model.My first and foremost priority and research goal is to help young investigators’ research and career development.