Publications

1974~1999;  273  Peer-reviewed Original Papers
Original papers (2000 ~)

  1. Hiroyuki Misawa, Masayoshi Yamaguchi:       Involvment of hepatic nuclear factor I binding motif in transcriptional regulation of Ca2+- binding protein regucalcin gene.       Biochemical and Biophysical Research Communications, 269:270-278 (2000).
  2. Hiroyuki Misawa, Masayoshi Yamaguchi: Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin. International Journal of Molecular Medicine, 5:283-287 (2000).
  3. Hiroyuki Misawa, Masayoshi Yamaguchi:      The gene of Ca2+-binding protein regucalcin is highly conserved in vertebrate species.   International Journal of Molecular Medicine, 6:191-196 (2000).
  4. Hiroyuki Misawa, Masayoshi Yamaguchi:  Intracellular signaling factors-enhanced hepatic nuclear protein binding to TTGGC sequence in the rat regucalcin gene promoter: Involvement of protein phosphorylation.      Biochemical and Biophysical Research Communications,　 279:275-281 (2000).
  5. Yoshinori Tsurusaki, Hiroyuki Misawa, Masayoshi Yamaguchi:  Translocation of regucalcin to rat liver nucleus: Involvement of nuclear protein kinase and protein phosphatase regulation.       International Journal of Molecular Medicine, 6:655-660 (2000).
  6. Yoshinori Tsurusaki, Masayoshi Yamaguchi: Suppressive effect of endogenous regucalcin on the enhancement of protein synthesis and aminoacyl-tRNA synthetase activity in regenerating rat liver. International Journal of Molecular Medicine, 6:295-299 (2000).
  7. Shyuichiroh Inagaki, Hiroyuki Misawa, Masayoshi Yamaguchi: Role of endogenous regucalcin in protein tyrosine phosphatase regulation in the cloned rat hepatoma cells (H4-II-E). Molecular and Cellular Biochemistry, 213:43-50 (2000).
  8. Shyuichiroh Inagaki, Masayoshi Yamaguchi: Enhancement of protein tyrosine phosphatase activity in the proliferation of cloned rat hepatoma H4-II-E cells: Suppressive role of endogenous regucalcin. International Journal of Molecular Medicine, 6:323-328 (2000).
  9. Hiroko Takahashi, Masayoshi Yamaguchi: Stimulatory effect of regucalcin on ATP-dependent Ca2+ uptake activity in rat liver mitochondria. Journal of Cellular Biochemistry, 78:121-130 (2000).
  10. Yoshinori Tsurusaki, Masayoshi Yamaguchi:  Role of endogenous regucalcin in the regulation of Ca2+-ATPase activity in rat liver nuclei.  Journal of Cellular Biochemistry, 78:541-549 (2000).
  11. Tomoko Baba, Masayoshi Yamaguchi: Stimulatory effect of regucalcin on proteolytic activity is impaired in the kidney cortex cytosol of rats with saline ingestion. Molecular and Cellular Biochemistry, 206:1-6 (2000).
  12. Jing Hui Xue, Hiroko Takahashi, Masayoshi Yamaguchi: Stimulatory effect of regucalcin on mitochondrial ATP-dependent calcium uptake activity in rat kidney cortex. Journal of Cellular Biochemistry, 80:285-292 (2000).
  13. Masayoshi Yamaguchi, Toshie Hamano, Hiroyuki Misawa: Expression of Ca2+-binding protein regucalcin in rat brain neurons: Inhibitory effect on protein phosphatase activity. Brain Research Bulletin,　52:343-348 (2000).
  14. Emi Sugimoto, Masayoshi Yamaguchi: Stimulatory effect of daidzein in osteoblastic MC3T3-E1 cells. Biochemical Pharmacology, 59:471-475 (2000).
  15. Emi Sugimoto, Masayoshi Yamaguchi: Anabolic effect of genistein in osteoblastic MC3T3-E1 cells. International Journal of Molecular Medicine, 5:515-520 (2000).
  16. Masayoshi Yamaguchi, Emi Sugimoto:  Stimulatory effect of genistein and daidzein on protein synthesis in osteoblastic MC3T3-E1 Cells: Activation of aminoacyl-tRNA synthetase.  Molecular and Cellular Biochemistry, 214:97-102 (2000).
  17. Ying Hua Gao, Masayoshi Yamaguchi: Suppressive effect of genistein on rat bone osteoclasts: Involvement of protein kinase inhibition and protein tyrosine phosphatase activation. International Journal of Molecular Medicine, 5:261-267 (2000).
  18. Masayoshi Yamaguchi, Hiroyuki Kakuda, Ying Hua Gao,  Yoshinori Tsukamoto: Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats. Journal of Bone and Mineral Metabolism, 18:71-76 (2000).
  19. Yoshinori Tsukamoto, Hideyuki Ichise, Hiroyuki Kakuda, Masayoshi Yamaguchi: Intake of fermented soybean (natto) increases circulating vitamin K2 (menaquinone-7) and g-carboxylated osteocalcin concentration in normal individuals. Journal of Bone and Mineral Metabolism, 18:216-222 (2000).
  20. Zhong Jie Ma, Masayoshi Yamaguchi:  Alteration in bone components with increasing age of newborn rats: role of zinc in bone growth.  Journal of Bone and Mineral Metabolism, 18:264-270 (2000).
  21. Masayoshi Yamaguchi, Ying Hua Gao, Zhong Jie Ma:  Synergistic effect of genistein and zinc on bone components in the femoral-metaphyseal tissues of female rats. Journal of Bone and Mineral Metabolism, 18:77-83 (2000).
  22. Shyuichiroh Inagaki, Masayoshi Yamaguchi: Suppressive role of protein kinase activity with proliferation of cloned rat hepatoma cells (H4-II-E). Journal of Cellular Biochemistry, 81 (S 36) : 12-18 (200l).
  23. Shyuichiroh Inagaki, Masayoshi Yamaguchi:  Regulatory role of endogenous regucalcin in the enhancement of nuclear deoxyribonucleic acid synthesis with proliferation of cloned rat hepatoma cells (H4-II-E).  Journal of Cellular Biochemistry, 82 : 704-711 (2001).
  24. Yoshiko Morooka, Masayoshi Yamaguchi:   Suppressive role of endogenous regucalcin in the regulation of protein phosphatase activity in rat renal cortex cytosol.   Journal of Cellular Biochemistry, 81 : 639-646 (2001).
  25. Yoshiko Morooka, Masayoshi Yamaguchi: Inhibitory effect of regucalcin on protein phosphatase activity in the nuclei of rat kidney cortex. Journal of Cellular Biochemistry, 83 : 111-120 (2001).
  26. Hiroko Takahashi, Masayoshi Yamaguchi: Activatory effect of regucalcin on GTPase activity in rat liver plasma membranes. Molecular and Cellular Biochemistry, 224 : 117-122 (2001).
  27. Hiroyuki Misawa, Masayoshi Yamaguchi: Involvement of nuclear factor-1 (NF1) binding motif in the regucalcin gene expression of rat kidney cortex: The expression is suppressed by cisplatin administration.  Molecular and Cellular Biochemistry, 219: 29-37 (2001).
  28. Toshie Hamano, Masayoshi Yamaguchi: Inhibitory role of regucalcin in the regulation of Ca2+-dependent protein kinase activity in rat brain neurons. Journal of the Neurological Sciences, 183: 33-38 (2001).
  29. Yasuko Hanahisa, Masayoshi Yamaguchi: Decrease in Ca2+-ATPase activity in the brain plasma membranes of rats with increasing age : Involvement of brain calcium accumulation. International Journal of Molecular Medicine, 7: 407-411 (2001).
  30. Hiroyuki Misawa, Masayoshi Yamaguchi: Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. International Journal of Molecular Medicine, 8: 513-520 (2001).
  31. Yoshinori Tsurusaki, Masayoshi Yamaguchi:  Suppressive effect of endogenous regucalcin on guanosine triphosphatase activity in rat liver nucleus.  Biological & Pharmaceutical Bulletine, 24: 958-961 (2001).
  32.  Zhong Jie Ma, Masayoshi Yamaguchi: Role of endogenous zinc in the enhancement of bone protein synthesis associated with bone growth of newborn rats. Journal of Bone and Mineral Metabolism, 19: 38-44 (2001).
  33.  Zhong Jie Ma, Masayoshi Yamaguchi:  Stimulatory effect of zinc on deoxyribonucleic acid synthesis in bone growth of newborn rats: Enhancement with zinc and insulin-like growth factor-I.  Calcified Tissue International, 69: 158-163 (2001).
  34. Zhong Jie Ma, Masayoshi Yamaguchi:  Stimulatory effect of zinc on insulin-like growth factor-I and transforming growth factor-β1 production with bone growth of newborn rats.       International Journal of Molecular Medicine, 8:623-628 (2001).
  35. Zhong Jie Ma, Masayoshi Yamaguchi: Stimulatory effect of zinc and growth factor on bone protein component in newborn rats: Enhancement with zinc and insulin-like growth factor-I. International Journal of Molecular Medicine, 7:73-78 (2001).
  36. Aki Igarashi, Masayoshi Yamaguchi:  Increase in bone growth factors with healing rat fractures: The enhancing effect of zinc.  International Journal of Molecular Medicine, 8:433-438 (2001).
  37. Masayoshi Yamaguchi, Emi Sugimoto, Sachiko Hachiya:  Stimulatory effect of menaquinone-7 (vitamin K2) on osteoblastic bone formation in vitro.  Molecular and Cellular Biochemistry, 223: 131-137 (2001).
  38. Masayoshi Yamaguchi, Zhong Jie Ma: Effect of polyphenols on calcium content and alkaline phosphatase activity in rat femoral tissues in vitro. Biological & Pharmaceutical Bulletin, 24: 1437-1439 (2001).
  39. Masayoshi Yamaguchi, Zhong Jie Ma:  Inhibitory effect of menaquinone-7 (vitamin K2) on osteoclast-like cell  formation and osteoclastic bone resorption in rat bone tissues in vitro.       Molecular and Cellular Biochemistry, 228: 39-47 (200l).
  40. Hiroyuki Misawa, Masayoshi Yamaguchi: Identification of transcription factor in the promoter region of rat regucalcin  gene: Binding of nuclear factor I-A1 to TTGGC motif. Journal of Cellular Biochemistry, 84: 795-802 (2002).
  41.  Yoshinori Tsurusaki, Masayoshi Yamaguchi: Suppressive role of endogenous regucalcin in the enhancement of  deoxyribonucleic acid synthesis activity in the nucleus of regenerating rat liver.      Journal of Cellular Biochemistry, 85: 516-522 (2002).
  42.  Hiroyuki Misawa, Shyuichiroh Inagaki, Masayoshi Yamaguchi:  Suppression of cell proliferation and deoxyribonucleic acid synthesis in  cloned rat hepatoma H4-II-E cells overexpressing regucalcin. Journal of Cellular Biochemistry, 84: 143-149 (2002).
  43.  Yoshiko Morooka, Masayoshi Yamaguchi:  Endogenous regucalcin suppresses the enhancement of protein phosphatase  activity in the cytosol and nucleus of kidney cortex in calcium-administered rats.    Journal of Cellular Biochemistry, 85: 553-560 (2002).
  44. Masayoshi Yamaguchi, Rie Nakajima:  Role of regucalcin as an activator of sarcoplasmic reticulum Ca2+-ATPase  activity in rat heart muscle.  Journal of Cellular Biochemistry, 86: 184-193 (2002).
  45.  Yoshiko Morooka, Masayoshi Yamaguchi:  Suppressive effect of endogenous regucalcin on deoxyribonucleic acid synthesis in the nuclei of rat renal cortex.  Molecular and Cellular Biochemistry, 229: 157-162 (2002).
  46. Masayoshi Yamaguchi, Zhong Jie Ma, Takashi Fusimi:  Anabolic effect of phosphogenistein and phosphodaidzein on bone components   in rat femoral-metaphyseal tissues in vitro.   Journal of Bone and Mineral Metabolism, 20: 148-155 (2002).
  47. Aki Igarashi, Masayoshi Yamaguchi: Characterization of the increase in bone 66 kDa protein component with healing  rat fractures: Stimulatory effect of zinc.   International Journal of Molecular Medicine, 9: 503-508 (2002).
  48. Hiroyuki Misawa, Masayoshi Yamaguchi: Identification of transcription factor in the promoter region of rat regucalcin gene: binding of nuclear factor I-A1 to TTGGC motif.   Journal of Cellular Biochemistry, 84: 795-802 (2002).
  49. Hiroyuki Misawa, Masayoshi Yamaguchi:  Gene expression for a novel protein RGPR-p117 in various species: The stimulation by intracellular signaling factors.  Journal of Cellular Biochemistry, 87: 188-193 (2002).
  50.  Yoshinori Tsurusaki, Masayoshi Yamaguchi:  Suppressive role of endogenous regucalcin in the enhancement of deoxyribonucleic acid synthesis activity in the nucleus of regenerating rat liver. Journal of Cellular Biochemistry, 85: 516-522 (2002).
  51. Yoshinori Tsurusaki, Masayoshi Yamaguchi: Role of endogenous regucalcin in nuclear regulation of regenerating rat liver: Suppression of the enhanced ribonucleic acid synthesis activity. Journal of Cellular Biochemistry, 87: 450-457 (2002).
  52. Hiroyuki Misawa, Shyuichiroh Inagaki, Masayoshi Yamaguchi: Suppression of cell proliferation and deoxyribonucleic acid synthesis in cloned rat hepatoma H4-II-E cells overexpression regucalcin. Journal of Cellular Biochemistry, 84: 143-149 (2002).
  53. Yoshiko Morooka, Masayoshi Yamaguchi: Endogenous regucalcin suppresses the enhancement of protein phosphatase activity in the cytosol and nucleus of kidney cortex in calcium-administered rats. Journal of Cellular Biochemistry, 85: 553-560 (2002).
  54. Masayoshi Yamaguchi, Rie Nakajima: Role of regucalcin as an activator of sarcoplasmic reticulum Ca2+-ATPase in rat heart muscle.
    Journal of Cellular Biochemistry, 86: 184-193 (2002).
  55. Masayoshi Yamaguchi, Yoshiko Morooka, Hiroyuki Misawa, Yoshinori Tsurusaki, Rie Nakajima: Role of endogenous regucalcin in transgenic rats: Suppression of kidney cortex cytosolic protein phosphatase activity and enhancement of heart muscle microsomal Ca2+-ATPase activity. Journal of Cellular Biochemistry, 86: 520-529 (2002).
  56. Yoshiko Morooka, Masayoshi Yamaguchi: Suppressive effect of endogenous regucalcin on deoxyribonucleic acid synthesis in the nuclei of rat renal cortex. Molecular and Cellular Biochemistry, 229: 157-162 (2002).
  57. Masayoshi Yamaguchi, Yoshinori Tsurusaki, Hiroyuki Misawa, Shyuichiroh Inagaki, Zhong Jie Ma, Hiroko Takahashi: Potential role of regucalcin as a specific biochemical marker of chronic liver injury with carbon tetrachloride administration in rats. Molecular and Cellular Biochemistry, 241: 61-67 (2002).
  58. Zhong Jie Ma, Masayoshi Yamaguchi: Suppressive role of endogenous regucalcin in the regulation of nitric oxide synthase activity in heart muscle cytosol of normal and regucalcin transgenic rats. International Journal of Molecular Medicine, 10: 761-766 (2002).
  59. Masayoshi Yamaguchi, Hiroyuki Misawa, Satoshi Uchiyama, Yoshiko Morooka, Yoshinori Tsurusaki: Role of endogenous regucalcin in bone metabolism: bone loss in induced in regucalcin transgenic rats. International Journal of Molecular Medicine, 10: 377-383 (2002).
  60. Aki Igarashi, Masayoshi Yamaguchi: Characterization of the increase in bone 66 kDa protein component with healing rat fractures: Stimulatory effect of zinc. International Journal of Molecular Medicine, 9: 503-508 (2002).
  61. Masayoshi Yamaguchi, Satoshi Uchiyama, Yoshinori Tsurusaki: Stimulatory effect of menaquinone-7 on bone formation in elderly female rat femoral tissues in vitro: Prevention of bone deterioration with aging. International Journal of Molecular Medicine, 10: 729-733 (2002).
  62. Masayoshi Yamaguchi, Zhong Jie Ma, Takashi Fushimi: Anabolic effect of phosphogenistein and phosphodaidzein on bone components in rat femoral-metaphyseal tissues in vitro. Journal of Bone and Mineral Metabolism, 20: 148-155 (2002).
  63. Yoshinori Tsurusaki, Masayoshi Yamaguchi: Overexpression of regucalcin modulates tumor-related gene expression in cloned rat hepatoma H4-II-E cells. Journal of Cellular Biochemistry, 90: 619-626 (2003).
  64. Takako Izumi, Yoshinori Tsurusaki, Masayoshi Yamaguchi: Suppressive effect of endogenous regucalcin on nitric oxide synthase activity in cloned rat hepatoma H4-II-E cells overexpressing regucalcin. Journal of Cellular Biochemistry, 89: 800-807 (2003).
  65. Masayoshi Yamaguchi, Hiroko Takahashi, Yoshinori Tsurusaki: Suppressive role of endogenous regucalcin in the enhancement of nitric oxide synthase activity in liver cytosol of normal and regucalcin transgenic rats. Journal of Cellular Biochemistry, 88: 1226-1234 (2003).
  66. Masayoshi Yamaguchi, Hiroyuki Misawa, Zhong Jie Ma: Novel protein RGPR-p117: The gene expression in physiologic state and the binding activity to regucalcin gene promoter region in rat liver. Journal of Cellular Biochemistry, 88: 1092-1100 (2003).
  67. Yoshinori Tsurusaki, Masayoshi Yamaguchi: Role of endogenous regucalcin in transgenic rats: Suppression of protein tyrosine phosphatase and ribonucleic acid synthesis activities in liver nucleus. International Journal of Molecular Medicine, 12: 207-211 (2003).
  68. Zhong Jie Ma, Masayoshi Yamaguchi: Regulatory effect of regucalcin on nitric oxide synthease activity in rat kidney cortex: Role of endogenous regucalcin in transgenic rats. International Journal of Molecular Medicine, 12: 201-206 (2003).
  69. Minako Tobisawa, Masayoshi Yamaguchi: Inhibitory role of regucalcin in the regulation of nitric oxide synthase activity in rat brain cytosol: involvement of aging. Journal of the Neurological Sciences, 209: 47-54 (2003).
  70. Minako Tobisawa, Masayoshi Yamaguchi: Suppressive effect of endogenous regucalcin on protein tyrosine phosphatase activity in the nucleus of rat brain: Attenuation with increasing age. International Journal of Molecular Medicine, 11: 205-210 (2003).
  71. Minako Tobisawa, Masayoshi Yamaguchi: Decrease in regucalcin level and enhancement of protein tyrosine phosphatase activity in rat brain microsomes with increasing age. International Journal of Molecular Medicine, 12: 577-580 (2003).
  72. Minako Tobisawa, Masayoshi Yamaguchi: Role of endogenous regucalcin in brain function: Suppression of cytosolic nitric oxide synthase and nuclear protein tyrosine phosphatase activities in brain tissue of transgenic rats.
  73. International Journal of Molecular Medicine, 12: 581-585 (2003).
  74. Masayoshi Yamaguchi, Aki Igarashi, Hiroyuki Misawa, Yoshinori Tsurusaki: Enhancement of albumin expression in bone tissues with healing rat fractures. Journal of Cellular Biochemistry, 89: 356-363 (2003).
  75. Aki Igarashi, Masayoshi Yamaguchi: Great increase in bone 66 kDa protein and osteocalcin at later stages with healing rat fractures: Effect of zinc treatment. International Journal of Molecular Medicine, 11: 223-228 (2003).
  76. Masayoshi Yamaguchi, Satoshi Uchiyama: Preventive effect of zinc acexamate administration in streptozotocin-diabetic rats: Restoration of bone loss. International Journal of Molecular Medicine, 12: 755-761 (2003).
  77. Satoshi Uchiyama, Masayoshi Yamaguchi: Alteration in serum and bone component findings induced in streptozotocin-diabetic rats is restored by zinc acexamate. International Journal of Molecular Medicine, 12: 949-954 (2003).
  78. Masayoshi Yamaguchi, Satoshi Uchiyama, Yoshinori Tsukamoto: Inhibitory effect of menaquinone-7 (vitamin K2) on the bone-resorbing factors-induced bone resorption in elderly female rat femoral tissues in vitro. Molecular and Cellular Biochemistry, 245: 115-120 (2003).
  79. Masayoshi Yamaguchi, Satoshi Uchiyama: Effect of carotenoid on calcium content and alkaline phosphase activity in rat femoral tissues in vitro: The unique anabolic effect of b-cryptoxanthin. Biological & Pharmaceutical Bulletin, 26: 1188-1191 (2003).
  80. Takako Izumi, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses cell death in cloned rat hepatoma H4-II-E cells induced by tumor necrosis factor-α or thapsigargin. Journal of Cellular Biochemistry, 92: 296-306 (2004).
  81. Takako Izumi, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses cell death and apoptosis in cloned rat hepatoma  H4-II-E cells induced by lipopolysaccharide, PD98059, dibucaine, or Bay K 8644. Journal of Cellular Biochemistry, 93: 598-608 (2004).
  82. Yuko Fukaya, Masayoshi Yamaguchi: Regucalcin increases superoxide dismutase activity in rat liver cytosol. Biological & Pharmaceutical Bulletin, 27: 1444-1446 (2004).
  83. Yoshinori Tsurusaki, Masayoshi Yamaguchi: Role of regucalcin in liver nuclear function: Binding of regucalcin to nuclear protein or DNA and modulation of tumor-related gene expression. International Journal of Molecular Medicine, 14: 277-281 (2004).
  84. Yuko Fukaya, Masayoshi Yamaguchi: Characterization of protein tyrosine phosphatase activity in rat liver microsomes: Suppressive effect of endogenous regucalcin in transgenic rats. International Journal of Molecular Medicine, 14: 427-432 (2004).
  85. Emiko Ichikawa, Masayoshi Yamaguchi: Regucalcin increases superoxide dismutase activity in the heart cytosol of normal and regucalcin transgenic rats. International Journal of Molecular Medicine, 14: 691-695 (2004).
  86. Masayoshi Yamaguchi, Aki Igarashi, Satoshi Uchiyama, Natsumi Sawada: Hyperlipidemia is induced in regucalcin transgenic rats with increasing age. International Journal of Molecular Medicine, 14: 647-651 (2004).
  87. Emiko Ichikawa, Yoshinori Tsurusaki, Masayoshi Yamaguchi: Suppressive effect of regucalcin on protein phosphatase activity in the heart cytosol of normal and regucalcin transgenic rats. International Journal of Molecular Medicine, 13: 289-293 (2004).
  88. Masayoshi Yamaguchi, Natsumi Sawada, Satoshi Uchiyama, Hiroyuki Misawa, Zhong Jie Ma: Expression of regucalcin in rat bone marrow cells: Involvement of osteoclastic bone resorption in regucalcin transgenic rats. International Journal of Molecular Medicine, 13: 437-443 (2004).
  89. Satoshi Uchiyama, Masayoshi Yamaguchi: Bone loss in regucalcin transgenic rats: Enhancement of osteocclastic cell formation from bone marrow of rats with increasing age. International Journal of Molecular Medicine, 14: 451-455 (2004). 90.  Koichi Ishida, Natsumi Sawada, Masayoshi Yamaguchi: Expression of albumin in bone tissues and osteoblastic cells: Involvement of hormonal regulation.
    International Journal of Molecular Medicine, 14: 891-895 (2004).
  90. Koichi Ishida, Masayoshi Yamaguchi: Role of albumin in osteoblastic cells: Enhancement of cell proliferation and suppression of alkaline phosphatase activity. International Journal of Molecular Medicine, 14: 1077-1081 (2004).
  91. Masayoshi Yamaguchi, Satoshi Uchiyama: Receptor activator of NF-κB ligand-stimulated osteoclastogenesis in mouse marrow culture is suppressed by zinc in vitro.  International Journal of Molecular Medicine, 14: 81-85 (2004).
  92. Masayoshi Yamaguchi, Satoshi Uchiyama: β-Cryptoxanthin stimulates bone formation and inhibits bone resorption in tissue culture in vitroMolecular and Cellular Biochemistry, 258: 137-144 (2004).
  93. Satoshi Uchiyama, Masayoshi Yamaguchi: Inhibitory effect of β-cryptoxanthin on osteclast-like cell formation in mouse
    marrow cultures. Biochemical Pharmacology, 67: 1297-1305 (2004).
  94. Satoshi Uchiyama, Takashi Sumida, Masayoshi Yamaguchi:Oral administration ofβ-cryptoxanthin induces anabolic effects on bone components in the femoral tissues of rats in vivo. Biological & Pharmaceutical Bulletin, 27: 232-235 (2004).
  95. Masayoshi Yamaguchi, Yuko Daimon: Overexpression of regucalcin suppresses cell proliferation in cloned rat hepatoma H4-II-E cells: Involvement of intracellular signaling factors and cell cycle-related genes. Journal of Cellular Biochemistry , 95: 1169-1177 (2005).
  96. S. Tuyoshi Ohnishi, Tomoko Ohnishi, Kozo Nishino, Yoshinori Tsurusaki, Masayoshi Yamaguchi: Growth inhibition of cultured human liver carcinoma cells by Ki-energy (life- energy): Scientific evidence for Ki-eefects on cancer cells.
  97. Evidence-Based Complementary and Alternative Medicine, 2: 387-393 (2005).
  98. Yuko Fukaya, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses cell death and apoptosis in cloned rat
    hepatoma H4-II-E cells induced by insulin or insulin-like growth factor-I. Journal of Cellular Biochemistry, 96: 145-154 (2005).
  99. Yuko Fukaya, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses apoptotic cell death in the cloned rat
    Hepatoma H4-II-E cells induced by a naturally occurring isothiocyanate  sulforaphane. International Journal of Molecular Medicine, 15: 853-857 (2005).
  100. Taeko Nakagawa, Masayoshi Yamaguchi: Hormonal regulation on regucalcin mRNA expression in cloned normal rat
    kidney proximal tubular epithelial NRK52E cells. Journal of Cellular Biochemistry, 95: 589-597 (2005).
  101. Taeko Nakagawa, Natumi Sawada, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses cell proliferation of cloned normal rat
    kidney proximal tubular epithelial NRK52E cells. International Journal of Molecular Medicine, 16: 637-643 (2005).
  102. Taeko Nakagawa, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses apoptotic cell death in cloned normal
    rat kidney proximal tubular epithelial NRK52E cells: change in apoptosis-related gene expression.
    Journal of Cellular Biochemistry, 96: 1274-1285 (2005).
  103. Masayoshi Yamaguchi, Satoshi Uchiyama: Regucalcin stimulates osteoclast-like cell formation in mouse marrow cultures.
    Journal of Cellular Biochemistry, 94: 794-803 (2005).
  104. Natsumi Sawada, Masayoshi Yamaguchi: A novel regucalcin gene promoter region-related protein: Comparison of
    nucleotide and amino acid sequences in vertebrate species. International Journal of Molecular Medicine, 15: 97-104 (2005).
  105. Natumi Sawada, Taeko Nakagawa, Tomiyasu Murata, Masayoshi Yamaguchi: Nuclear localization of a novel protein, RGPR-p117, in cloned normal rat kidney proximal tubular epithelial cells. International Journal of Molecular Medicine, 16: 809-814 (2005).
  106. Natsumi Sawada, Masayoshi Yamaguchi: Overexpression of RGPR-p117 enhances regucalcin gene expression in cloned
    normal rat kidney proximal tubular epithelial cells. International Journal of Molecular Medicine, 16: 1049-1055 (2005).
  107. Masayoshi Yamaguchi, Mayumi Kobayashi, Satoshi Uchiyama: Suppressive effect of regucalcin on cell differentiation and mineralization in
    osteoblastic MC3T3-E1 cells. Journal of Cellular Biochemistry, 96: 543-554 (2005).
  108. Koichi Ishida, Masayoshi Yamaguchi: Albumin regulates Runx2 and α1(I) collagen mRNA expression in osteoblastic cells: Comparison with insulin-like growth factor-I. International Journal of Molecular Medicine, 16: 689-694 (2005).
  109. Satoshi Uchiyama, Masayoshi Yamaguchi: β-Cryptoxanthin stimulates cell proliferation and transcriptional activity in osteoblastic MC3T3-E1 cells. International Journal of Molecular Medicine, 15: 675-681 (2005).
  110. Satoshi Uchiyama, Masayoshi Yamaguchi: β-Cryptoxanthin stimulates cell differentiation and mineralization in osteoblastic MC3T3-E1 cells. Journal of Cellular Biochemistry, 95: 1224-1234 (2005).
  111. Satoshi Uchiyama, Masayoshi Yamaguchi: Oral administration ofβ-cryptoxanthin prevents bone loss in streptozotocin-diabetic rats in vivo.
    Biological & Pharmaceutical Bulletin, 28: 1766-1769 (2005).
  112. Satoshi Uchiyama, Kaori Ishiyama, Ken Hashimoto, Masayoshi Yamaguchi: Synergistic effect ofβ-cryptoxanthin and zinc sulfate on the bone component in rat femoral tissues in vitro: The unique anabolic effect with zinc. Biological & Pharmaceutical Bulletin, 28: 2142-2145 (2005).
  113. Masayoshi Yamaguchi, Masayo Fukagawa: Role of zinc in regulation of protein tyrosine phosphatase activity in osteoblastic MC3T3-E1 cells: Zinc modulation of insulin-like growth factor-I’s effect. Calcified Tissue International, 76: 32-38 (2005).
  114. Ying Ling Lai, Masayoshi Yamaguchi: Effect of copper on bone component in the femoral tissues of rats: Anabolic effect of zinc is weakened by copper. Biological & Pharmaceutical Bulletin, 28: 2296-2301 (2005).
  115. Taeko Nakagawa, Masayoshi Yamaguchi: Overexpression of regucalcin enhances its nuclear localization and suppresses   L-type Ca2+ channel and calcium-sensing receptor mRNA expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells Journal of Cellular Biochemistry, 99:1064-1077(2006).
  116. Chikage Nakashima, Masayoshi Yamaguchi: Overexpression of regucalcin enhances glucose utilization and lipid production in cloned rat hepatoma H4-II-E cells: Involvement of insulin resistance. Journal of Cellular Biochemistry, 99:1582-1592 (2006).
  117. Tania Akhter, Natsumi Sawada, Masayoshi Yamaguchi: Regucalcin increases Ca2+-ATPase activity in the heart mitochondria of normal
    and regucalcin transgenic rats.  International Journal of Molecular Medicine, 18:171-176(2006).
  118. Yasuko Otomo, Masayoshi Yamaguchi: Regulatory effect of exogenous regucalcin on cell function is osteoblastic MC3T3-E1 cells: Involvement of intracellular signaling factor. International Journal of Molecular Medicine, 18:321-327(2006).
  119. Natsumi Sawada, Masayoshi Yamaguchi: Involvement of nuclear factor I-A1 in the regulation of regucalcin gene promoter activity in cloned normal rat kidney proximal tubular epithelial cells. International Journal of Molecular Medicine, 18:665-671(2006).
  120. Natsumi Sawada, Masayoshi Yamaguchi: Overexpression of RGPR-p117 enhances regucalcin gene promoter activity in cloned normal rat kidney proximal tubular epithelial cells: Involvement of TTGGC motif. Journal of Cellular Biochemistry, 99:589-597(2006).
  121. Satoshi Uchiyama, Masayoshi Yamaguchi: β-Cryptoxanthin stimulates apoptotic cell death and suppresses cell function in osteoblastic cells: Change in their related gene expression. Journal of Cellular Biochemistry, 98:1185-1195(2006).
  122. Satoshi Uchiyama, Masayoshi Yamaguchi: Oral administration ofβ-cryptoxanthin prevents bone loss in ovariectomized
    rats. International Journal of Molecular Medicine, 17:15-20(2006).
  123. Masayoshi Yamaguchi, Satoshi Uchiyama, Kaori Ishiyama, Ken Hashimoto: Oral administration in combination with with zinc enhancesβ-cryptoxanthin-induced anabolic effects on bone components in the femoral tissues of rats in vivo.Biological & Pharmaceutical Bulletin, 29:371-374(2006).
  124. Ying Ling Lai, Masayoshi Yamaguchi: Phytocomponent p-hydroxycinnamic acid stimulates bone formation and inhibits bone resorption in rat femoral tissues in vitro. Molecular and Cellular Biochemistry, 292:45-52(2006).
  125. Ying Ling Lai, Masayoshi Yamaguchi: Oral administration of phytocomponent p-hydroxycinnamic acid has anabolic effects on bone calcification in femoral tissues of rats in vivo. Journal of Health Science, 52:308-312(2006).
  126. Saburo Hidaka, Yoshizo Okamoto, Satoshi Uchiyama, Akira Nakatsuma, Ken Hashimoto, S. Tuyoshi Ohnishi, Masayoshi Yamaguchi:
    Royal jelly prevents osteoporosis in rats: Benefical effects in ovariectomy model and in bone tissue culture model. Evidence-Based Complementary and Alternative Medicine, 3:339-348 (2006).
  127. Satoshi Uchiyama, Shigeo Kouno, Masayoshi Yamaguchi: Oral administration of Saldi tiera containing various trace elements has
    anabolic effects on bone component in the femoral tissues of rats. Journal of Health Science, 52:412-418 (2006).
  128. Taeko Nakagawa, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses cell response for tumor necrosis factor-α or transforming growth factor-β1 in cloned normal rat kidney proximal tubular epithelial NRK52E cells. Journal of Cellular Biochemistry, 100:1178-1190 (2007).
  129. Masayoshi Yamaguchi, Taeko Nakagawa: Change in lipid components in the adipose and liver tissues of regucalcin transgenic rats with increasing age: Suppression of leptin and adiponectin gene expression. International Journal of Molecular Medicine, 20: 323-328 (2007).
  130. Chikage Nakashima, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses gene expression of insulin signaling-
    Related proteins in cloned rat hepatoma H4-II-E cells: Involvement of insulin resistance. International Journal of Molecular Medicine, 20: 709-716 (2007).
  131. Tania Akhter, Taeko Nakagawa, Akiko Kobayashi, Masayoshi Yamaguchi: Suppression of regucalcin mRNA expression in the hearts of rats administered with free radical compound: The administration-induced death is accelerated in regucalcin transgenic rats. International Journal of Molecular Medicine, 19:653-658 (2007).
  132. Susumu Tomono, Natumi Sawada, Masayoshi Yamaguchi: Overexpression of RGPR-p117 induces the decrease in protein and DNA
    contents in cloned normal rat kidney proximal tubular epithelial NRK52E cells. International Journal of Molecular Medicine, 20:79-83 (2007).
  133. Masayoshi Yamaguchi, Susumu Tomono, Taeko Nakagawa: Overexpression of RGPR-p117 suppresses apoptotic cell death and its related gene expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells. International Journal of Molecular Medicine, 20: 565-571 (2007).
  134. Satoshi Uchiyama, Masayoshi Yamaguchi: Genistein and zinc synergistically enhance gene expression and mineralization in osteoblastic MC3T3-E1 cells. International Journal of Molecular Medicine, 19:213-220 (2007).
  135. 135.   Satoshi Uchiyama, Masayoshi Yamaguchi: Genistein and zinc synergistically stimulate apoptotic cell death and suppress RANKL siganaling-related gene expression in osteoblastic cells. Journal of Cellular Biochemistry, 101:529-542 (2007).
  136. Ying Ling Lai, Masayoshi Yamaguchi: Phytocomponent p-hydroxycinnamic acid inhibits osteoclast-like cell formation in mouse bone marrow cultures. International Journal of Molecular Medicine, 19:123-128 (2007).
  137. Masayoshi Yamaguchi, Satoshi Uchiyama, Ying Ling Lai: Oral admnistration of phytocomponent p-hydroxycinnamic acid has a Preventive effect on bone loss in streptozotocin-induced diabetic rats. International Journal of Molecular Medicine, 19:803-807 (2007).
  138. S. Tuyoshi Ohnishi, Kozo Nishino, Satoshi Uchiyama, Tomoko Ohnishi, Masayoshi Yamaguchi: Ki-energy (life-energy) stimulates osteoblastic cells and inhibits the formation of osteoclast-like cells in bone cell culture models. Evidence-Based Complementary and Alternative Medicine, 4: 225-232 (2007).
  139. Masayoshi Yamaguchi, Reiko Hamamoto, Satoshi Uchiyama, Kaori Ishiyama: Effects of flavonoid on calcium content in femoral tissue culture and parathyroid hormone-stimulated osteoclastogenesis in bone marrow culture in vitro. Molecula and Cellular Biochemistry, 303: 83-88 (2007).
  140. Taeko Nakagawa, Masayoshi Yamaguchi: Nuclear localization of regucalcin is enhanced in culture with protein kinase C Activation in cloned normal rat kidney proximal tubular epithelial NRK52E cells. International Journal of Molecular Medicine, 21:605-610 (2008).
  141. Masayoshi Yamaguchi, Yusei Takakura, Taeko Nakagawa: Regucalcin increases Ca2+-ATPase activity in the mitochondria of brain tissues of normal and transgenic rats. Journal of Cellular Biochemistry, 104: 795-804(2008).
  142. Masayoshi Yamaguchi, Yasuko Otomo, Satoshi Uchiyama, Taeko Nakagawa: Hormonal regulation of regucalcin mRNA expression in osteoblastic MC3T3-E1 cells. International Journal of Molecular Medicine, 21: 771-775 (2008).
  143. Masayoshi Yamaguchi, Maya Goto, Satoshi Uchiyama, Taeko Nakagawa: Effect of zinc on gene expression in osteoblastic MC3T3-E1 cells: enhancement of Runx2, OPG, and regucalcin mRNA expressions. Molecular and Cellular Biochemistry, 312:157-66 (2008).
  144. Satoshi Uchiyama, Masayoshi Yamaguchi: Anabolic effect of β-cryptoxanthin in osteoblastic MC3T3-E1 cells is enhanced with 17β-estradiol, genistein, or zinc sulfate in vitro: the unique effect with zinc on Runx2 and α1(I) collagen mRNA expressions. Molecular and Cellular Biochemistry, 307:209-219 (2008).
  145. Masayoshi Yamaguchi, Ying Ling Lai, Satoshi Uchiyama, Taeko Nakagawa: Oral administration of phytocomponent p-hydroxycinnamic acid prevents bone loss in ovariectomized rats. Molecular and Cellular Biochemistry, 311:31-36 (2008).
  146. Masayoshi Yamaguchi, Satoshi Uchiyama: Combination of β-cryptoxanthin and zinc has potent effects on apoptotic cell death and suppression of bone resorption-related gene expression in osteoblastic cells. International Journal of Molecular Medicine, 22:221-228 (2008).
  147. Masayoshi Yamaguchi, Ying Ling Lai, Satoshi Uchiyama, Taeko Nakagawa: Phytocomponent p-hydroxycinnamic acid stimulates mineralization in osteoblastic MC3T3-E1 cells. International Journal of Molecular Medicine, 22:287-291 (2008).
  148. Masayoshi Yamaguchi, M. Neale Weitzmann: The estrogen 17β-estradiol and phytoestrogen genistein mediate differential effects on osteoblastic NF-κB activity. International Journal of Molecular Medicine, 23:297-301 (2009).
  149. Masayoshi Yamaguchi, M. Neale Weitzmann: The bone anabolic carotenoids p-hydroxycinnamic acid and β-cryptoxanthine NF-κB activation in MC3T3 preosteoblasts. Molecular Medicine Reports, 2: 641-644 (2009).
  150. Masayoshi Yamaguchi, M. Neale Weitzmann: The bone anabolic carotenoid β-cryptoxanthin enhaces transforming growth factor-β1-induced SMAD activation in MC3T3 preosteoblasts.  International Journal of Molecular Medicine, 24:671-675 (2009).
  151. Tatyana Vikulina, Xian Fan, Masayoshi Yamaguchi, Susanne Roser-Page, Majd Zayzafoon, David M. Guidot, Ighovwerha Ofotokun,
    M. Neale Weitzmann: Alterations in the immuno-skeletal interface drive bone destruction in HIV-1 transgenic rats. Proceedings of the National Academy of Sciences USA, 107:13848-13853  (2010).
  152. Masayoshi Yamaguchi, M. Neale Weitzmann: Vitamin K2 stimulates osteoblastogenesis and suppresses osteoclastogenesis by
    NF-κB activation. International Journal of Molecular Medicine, 27:3-14 (2011).
  153. Masayoshi Yamaguchi, M. Neale Weitzmann: Zinc stimulates osteoblastogenesis and suppresses osteoclastogenesis by
    antagonizing NF-κB activation. Molecular and Cellular Biochemistry, 355:179-186(2011).
  154. Masayoshi Yamaguchi, M. Neale Weitzmann: Quercetin, a potent suppressor of NF-kB and Smad activation in osteoblasts.
    International Journal of Molecular Medicine, 28:521-525 (2011).
  155. Masayoshi Yamaguchi, Jack L. Arbiser, M. Neale Weitzmann: Honokiol stimulates osteoblastogenesis by suppressing NF-kB activation.
    International Journal of Molecular Medicine, 28: 1049-1053 (2011)
  156. Masayoshi Yamaguchi, M. Neale Weitzmann, Tomiyasu Murata:   Exogenous regucalcin stimulates osteoclastogenesis and suppresses
    osteoblastogenesis through NF-kB activation. Molecular and Cellular Biochemistry, 359: 193-203 (2012)
  157. Masayoshi Yamaguchi, M. Neale Weitzmann: The intact strontium ranelate complex stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-kB activation. Molecular and Cellular Biochemistry, 359: 399-407 (2012)
  158. Masayoshi Yamaguchi, M. Neale Weitzmann: High dose 1,25(OH)2D3 inhibits osteoblast mineralization in vitro. International Journal of Molecular Medicine, 29:934-938 (2012)
  159. George R. Beck Jr, Shin-Woo Ha, Corinne E. Camalier, Masayoshi Yamaguchi, Yan Li, Jin-Kyu Lee, M. Neale weitzmann: Bioactive silica based nanoparticles stimulate bone forming osteoblasts, suppress bone resorbing osteoclasts, and enhance bone mineral density in vivo.Nanomedicine, 8: 793-803 (2012).
  160. Masayoshi Yamaguchi, Terry M. Moore, Aiming Sun , James P. Snyder, Mamoru Shoji: Novel curcumin analogue UBS 109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: Involement in Smad activation and NF-κB inhibition. Integrative Biology, 4: 905-913 (2012)
  161. Masayoshi Yamaguchi, M. Neale Weitzmann: The bone anabolic carotenoid p-hydroxycinnamic acid promotes osteoblast mineralization and suppresses osteoclast differentiation by antagonizing NF-κB activation. International Journal of Molecular Medicine, 30: 708-712 (2012)
  162. Masayoshi Yamaguchi, M. Neale Weitzmann, Clifton A Baile, Tomiyasu Murata: Exogenous regucalcin suppresses osteoblastogenesis and stimulates adipogenesis in mouse bone marrow culture. Integrative Biology, 4: 1215-1222 (2012).
  163. Masayoshi Yamaguchi, Toru Matsumoto: Marine algae Sargassum horneri bioactive factor stimulates osteoblastogenesis 
    and suppresses osteoclastogenesis in vitro. OA Biotechnology, 1:3 (2012).
  164. Masayoshi Yamaguchi, Clifton A. Baile, Shijun Zhu, Mamoru Shoji: Bioactive flavonoid p-hydroxycinnamic acid stimulates osteoblastogenesis and suppresses adipogenesis in bone marrow culture. Cell and Tissue Research, 354:743-750 (2013).
  165. Masayoshi Yamaguchi, Tatyana Vikulina, Jack L. Arbiser, M. Neale Weitzmann: Suppression of NF-kB activation by gentian violet promotes osteoblastogenesis and suppresses osteoclastogenesis. Current Molecular Medicine, 14:783-792 (2014) Masayoshi Yamaguchi,
  166. Shijun Zhu, Shumin Zhang, Daqing Wu, Terry M. Moore, James P. Snyder, Mamoru Shoji: Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: Involvement in osteoblastogenesis and osteoclastogenesis. Cell and Tissue Research, 357:245-252 (2014)
  167. Tomiyasu Murata, Masayoshi Yamaguchi: Alternatively spliced variants of the regucalcin gene in various human normal and tumor tissues. International Journal of Molecular Medicine, submitted (2014)
  168. Masayoshi Yamaguchi, Toru Matsumoto: Marine algae Sargassum horneri bioactive factor suppresses adipogenesis in  mouse bone marrow culture in vitro. OA Biotechnology  3:7 (2014)
  169. Masayoshi Yamaguchi, Shijun Zhu, M. Neale Weitzmann, James P. Snyder, Mamoru Shoji: Curcumin analog UBS109 prevents bone marrow osteoblastogenesis and osteoclastogenesis disordered by coculture with breast cancer MDA-MB-231 bone metastatic cells in vitro. Submitted (2014)

Review Publications (Peer-reviewed)

Review Publications (Peer-reviewed)

  1. Masayoshi Yamaguchi: Calcitonin and liver metabolism: Role of cellular calcium.Life Science Advance in Experimental and Clinical Endocrinology, 8: 29-36 (1989).
  2. Masayoshi Yamaguchi: Role of zinc as an activator of bone formation.Journal of Nutrition and Vitaminology (Tokyo), Special Issue, p. 522-525, 1992.
  3. Masayoshi Yamaguchi: β-Alanyl-L-histidinato zinc and bone resorption: A potent activator in bone formation. Current Medicinal Chemistry, 1: 356 – 365 (1995).
  4. Masayoshi Yamaguchi:  β-Alanyl-L-histidinato zinc and bone resorption.General Pharmacology, 26: 1179 – 1183 (1995).
  5. Masayoshi Yamaguchi: Role of zinc in bone formation and bone resorption. Journal of Trace Elements in Experimental Medicine,　11: 119 –135 (1998).
  6. Masayoshi Yamaguchi: Role of calcium-binding protein regucalcin in regenerating rat liver. Journal of Gastroenterology and Hepatology 13 (Supplement): S106-S112, 1998.
  7. Masayoshi Yamaguchi: Role of regucalcin in calcium signaling.Life Sciences,　66: 1769 – 1780 (2000).
  8. Masayoshi Yamaguchi: The role of regucalcin in nuclear regulation of regenerating liver.Biochemical and Biophyseal Research Communications,　276: 1- 6 (2000).
  9. Masayoshi Yamaguchi: Isoflavon and bone metabolism: Its cellular mechanism and preventive role in bone loss. Journa of Health Science, 　48: 209-222 (2002).
  10. Masayoshi Yamaguchi, Satoshi Uchiyama: Preventive effect of zinc acexamate administration on bone loss in  streptozotocin- induced diabetic rats: Comparison with zinc sulfate.  Biomedical Research on Trace Elements, 14: 233-238 (2003).
  11. Masayoshi Yamaguchi: Role of zinc in regulation of osteoclastogenesis. Biomedical Research on Trace Elements 15: 9-14 (2004).
  12. Masayoshi Yamaguchi: Role of regucalcin in maintaining cell homeostasis and function (Review). International Journal of Molecular Medicine, 15: 371-389 (2005).
  13. Masayoshi Yamaguchi: Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis. Yakugaku Zasshi, 126:1117-1137(2006).
  14. Masayoshi Yamaguchi: Role of zinc in bone metabolism and preventive effect on bone disorder. Biomedical Research on Trace Elements, 18:346-366 (2007).
  15. Masayoshi Yamaguchi: β-Cryptoxanthin and bone metabolism: The preventive role in osteoporosis.Journal of Health Science, 54: 356-369 (2008).
  16. Masayoshi Yamaguchi: Novel protein RGPR-p117: its role as the regucalcin gene transcription factor.   Molecular and Cellular Biochemistry, 327: 53-63 (2009).
  17. Masayoshi Yamaguchi: Role of nutritional zinc in the prevention of osteoporosis. Molecular and Cellular Biochemistry, 338: 241-254 (2010).
  18. Masayoshi Yamaguchi: Regucalcin and metabolic disorder: osteoporosis and hyperlipidemia are induced in regucalcin transgenic rats. Molecular and Cellular Biochemistry, 341: 119-133 (2010).
  19. Masayoshi Yamaguchi: The transcriptional regulation of regucalcin gene expression. Molecular and Cellular Biochemistry, 346: 147-171 (2011)
  20. Masayoshi Yamaguchi: Regucalcin and cell regulation: role as a suppressor in cell signaling. Molecular and Cellular Biochemistry, 353:101-137 (2011)
  21. Ying Hua Gao-Balch, Lisa D. Privett, Masayoshi Yamaguchi The theoretical strategy for overweight and obesity intervention programs in  adult population. International Journal of Medicine and Medical Sciences, 36:164-169 (2011)
  22. Masayoshi Yamaguchi: Role of regucalcin in brain calcium signaling:  Involevement with aging.  Integrative Biology, 4:825-837 (2012).
  23. Masayoshi Yamaguchi: Nutritional factors and bone homeostasis: Synergistic  effect of zinc and genistein osteogenesis.  Molecuclar and Cellular Biochemistry, 366:201-221 (2012)
  24. Masayoshi Yamaguchi: Role of beta-cryptoxanthin in bone homeostasis.  Journal of Biomedical Science, 19:36-48 (2012)
  25. Masayoshi Yamaguchi: Role of regucalcin in brain calcium signaling: Involevement in aging. Intergrative Biology, 4: 825-837 (2012).
  26. Masayoshi Yamaguchi: Regucalcin may be a target molecule in diabetes.  Endocrinology & Metabolic Syndrome 1:e112 (2012).  doi.10.4172/2161-1017.1000e112
  27. Masayoshi Yamaguchi: Bone anabolic effect of wasabi leafstalk components: Its  related phytochemical p-hydroxycinnamic acid prevents osteoporosis. Open Access Scientific Reports 1: 194 (2012). doi.10.4172/scientificreports.194
  28. Masayoshi Yamaguchi: Regucalcin: new development on biotechnology.  OA Biotechnology, 1:1 (2012)
  29. Masayoshi Yamaguchi: Regucalcin, cell signaling-related protein: its  multifunctional role in kidney cell regulation.  OA Biotechnology 1:2 (2012)
  30. Masayoshi Yamaguchi: Marine alga Sargassum horneri component and bone homeostasis: Role in osteoporosis prevention.  International Journal of Food Science, Nutrition and Dietetics, 2:101 (2013)
  31. Masayoshi Yamaguchi, Ying Hua Gao-Balch: Role of dietary soybean genistein in osteoporosis  revention.  International Journal of Food Science, Nutrition and Dietetics, 2:102 (2013)
  32. Masayoshi Yamaguchi, Tomiyasu Murata: Involvement of regucalcin in lipid  metabolism and diabetes. Metabolism, 62:1045-1051  (2013)
  33. Masayoshi Yamaguchi: Suppressive role of regucalcin in liver cell proliferation:  Involvement in carcinogenesis. Cell Proliferation, 46:243-253 (2013)
  34. Masayoshi Yamaguchi: The osteogenic effect of bioactive flavonoid p-hydroxycinnamic acid: Development on osteoporosis treatment. OA Biotechnology  2:15 (2013)
  35. Masayoshi Yamaguchi: Suppressive role of regucalcin in protein output in liver cells. OA Biotechnology  2:6 (2013)
  36. Masayoshi Yamaguchi: The anti-apoptotic effect of regucalcin is mediated through multisignaling pathways.  Apoptosis 18:1145–1153 (2013)
  37. Masayoshi Yamaguchi: Hormonal regulation of regucalcin gene expression: Involvement in cell metabolism.Hormonal Studies 1:1 (2013). doi: 10.7243/2052-8000-1-1
  38. Masayoshi Yamaguchi: Role of regucalcin in cell nuclear regulation: Involvement as a transcription factor Cell and Tissue Research  354:331-341(2013)
  39. Masayoshi Yamaguchi: New development in osteoporosis treatment: The synergistical osteogenic effects with vitamin D3, MK-7, genistein and zinc  Vitamins & Minerals,  S6: e001. doi:10.4172/vms.S6-e001
  40. Masayoshi Yamaguchi: Novel Protein RGPR-p117: New aspects in cell regulation. Journal of Molecular and Genetic Medicine 7: 072 (2013) doi:10.4172/1747-0862.1000072
  41. Masayoshi Yamaguchi: Regucalcin may be a key molecule in cell nuclear regulation. Biochemistry & Physiology, 2:e116 (2013). doi: 10.4172/2168-9652.1000e116
  42. Masayoshi Yamaguchi: Osteoporosis treatment with new osteogenic factors. Journal Molecular and Genetic Medicine 7:66 (2013).      http://dx.doi.org/10.4172/1747-0862.1000066
  43. Masayoshi Yamaguchi: Bone marrow mesenchymal stem cell differentiation: Involvement in osteoporosis  with obesity and diabetes. Journal of Bone Marrow Research 1:e107 (2013). doi: 10.4172/2329-8820.1000e107
  44. Masayoshi Yamaguchi:  Calcium regulatory protein, regucalcin, may be a target molecule in brain disease.  Journal of Molecular and Genetic Medicine 7:87 (2013). doi: 10.4172/1747- 0862.1000087
  45. Masayoshi Yamaguchi: Osteoporosis: development of new osteogenic factor. Journal of Osteoporosis and Physical Activity 1:e106 (2013).  Doi:10 4172/2329-9509 1000e106
  46. Masayoshi Yamaguchi: Role of regucalcin in bone homeostasis: Involvement as a novel cytokine. Integrative Biology,6: 258-266 (2014)
  47. Masayoshi Yamaguchi: Regucalcin as a potential biomarker for metabolic and neuronal diseases. Molecular and Cellular Biochemistry, 391:157–166 (2014)
  48. Masayoshi Yamaguchi: New aspects in obesity and diabetes: Involvement in regucalcin, a suppressor  protein of cell signaling. Journal of Molecular and Genetic Medicine, S1: 010 (2014).  doi: 10.4172/1747-0862.S1-010
  49. Masayoshi Yamaguchi: The regucalcin gene is a key in the therapy of hepatocellular carcinoma. Journal of Cancer Science & Therapy, 6: e132 (2014).  doi:10.4172/1948-5956.1000e132
  50. Masayoshi Yamaguchi: Osteoporosis treatment with functional food factor: Vitamin K2.Journal of Osteoporosis & Physical Activity, 2:1 (2014). doi:10.4172/2329-9509.1000e108
  51. Masayoshi Yamaguchi: Regulatory role of regucalcin in heart calcium signaling: Insight into cardiac  failaure (Review). Biomedical Reports, 2:303-308 (2014).
  52. Masayoshi Yamaguchi: Potential significance of the regucalcin gene in human carcinoma Integrative Cancer Science and Therapeutics 1:1 (2014)
  53. Masayoshi Yamaguchi: The suppression of regucalcin gene expression may lead to  hepatocarcinogenesis  Integrative Cancer Science and Therapeutics  1:1 (2014)
  54. Masayoshi Yamaguchi: Regucalcin serves as a suppressor protein in hepatocarcinogenesis  Cell Signaling and Cancer    1: 101 (2014)
  55. Masayoshi Yamaguchi: Regucalcin, a novel regulatory protein implicated in obesity  and diabetes Integrative Molecular Medicine   1:1 (2014)
  56. Masayoshi Yamaguchi: Osteoporosis and obese type 2 diabetes: Prevention with osteogenic factors Journal of Molecular Obesity and Diabetes 1: e101 (2014)
  57. Masayoshi Yamaguchi: Osteoporosis prevention with functional food factors Functional Food and Biomedicine  1: 101 (2014)
  58. Masayoshi Yamaguchi: Role of nutritional factor menaquinone-7 in bone homeostasis and   osteoporosis prevention Integrative Molecular Medicine,  1:1-6 (2014), doi:10.15761.IMM/1000101
  59. Masayoshi Yamaguchi: Type 1 diabetic bone loss is prevented by novel osteogenic  factors Integrative Obesity and Diabetes, 1:7-10 (2014), doi: 10.15761/IMM.1000102
  60. Masayoshi Yamaguchi Marine alga Sargassum horneri active component: Involvement in the Improvement of obese diabetic bone loss. Integrative Food, Nutrition and Metabolism  1:1 (2014)

Book and Book chapter

  1. Masayoshi Yamaguchi: Calcitonin and calcium metabolism in hepatic bile. In: Calcium Endocrinology, Editors; Yoshitoshi Y, Fujita T,  Chugai Igaku, Tokyo, p. 169-183, 1980.
  2. Masayoshi Yamaguchi: A novel Ca2+-binding protein regucalcin and calcium inhibition: Regulatory role in liver cell function. In: Calcium Inhibition, Editor; Kohama K, Japan Scientific Societies Press, Tokyo and CRC Press, Boca Raton, p.19-41, 1992.
  3. Masayoshi Yamaguchi: Alteration of bone metabolism: Effect of nutrition. In : Pathology of the Aging Rat,, Editors; Mohr U,  Dungworth DL, Capen CC, ILSI Press, Washington, D. C ., Vol. 2, p. 499-511, 1994.
  4. Masayoshi Yamaguchi:  Impact of aging on calcium channels and pumps.   In: Calcium and Signaling in Aging. Editor; Mattson MP, Elsevier Science,  p. 47-65, 2002.
  5. Masayoshi Yamaguchi:      Regucalcin and cell siganaling: Overexpression of regucalcin suppresses cell       death and apoptosis.      In: Second Messengers and Phosphoprotein Signaling. Editors; Anand-Srivastava MB, Tremblay M, Srivastava AK, Medimond S.r.l.,      p. 225-230, 2004. 
  6. Masayoshi Yamaguchi, Satoshi Uchiyama Osteoporosis prevention by β-cryptoxanthin. In: Functional Food and Health, Editors; Shibamoto T, Kanazawa K, Shahidi F, Ho C-T, ACS Symposium Series 993; American Chemical Society, Washington, D.C., Oxford University Press, Chapter 35, p.408-418, 2008.
  7. Masayoshi Yamaguchi: Nutritional factors and osteoporosis prevention. In: Nutritional Biochemistry: Genomics, Metabolomics and Food Supply, Editors; Haugen S, Meijer S, Nova Science Publishers, Inc., New York, USA, Chapter 1, p.1-84, 2010
  8. Masayoshi Yamaguchi: Nutritional Factors and Osteoporosis Prevention. Nova Science Publishers, Inc., New York, USA, 2010.
  9. Masayoshi Yamaguchi: Carotenoids and bone homeostasis: Role in osteoporosis prevention. In: Carotenoids: Properties, Effects and Diseases, Editor; Yamaguchi M, Nova Science Publishers, Inc., New York, USA, Chapter 10, pp.259-286, 2011
  10. Masayoshi Yamaguchi: Regucalcin: Role as a suppressor protein in calcium signaling. In: Calcium Signaling, Editor; Yamaguchi M,
    Nova Science Publishers, Inc., New York, USA, Chapter 8, pp.159-214, 2011
  11. Masayoshi Yamaguchi: Regucalcin: Genomics, Cell Regulation and Disease. Nova Science Publishers, Inc., New York, USA, 2012.
  12. Masayoshi Yamaguchi: Vitamin K and osteocalcin: Role of osteoporosis prevention. In: Osteocalcin: Production,Regulation and Disease, Editor; Yamaguchi M, Nova Science Publishers, Inc., New York, USA, Chapter 9, pp.72-90, 2012
  13. Masayoshi Yamaguchi: Hyperlipidemia induced in regucalcin transgenic rats: Involvement of adiponectin. In: Adiponectin: Production, Regulation and Roles in Disease, Editor; Yamaguchi M, Nova Science Publishers, Inc., New York, USA, Chapter 14, pp.105-120, 2012
  14. Masayoshi Yamaguchi: Zinc and bone homeostasis: Role of zinc supplementation in osteoporosis Prevention. In: Zinc: Characteristics, Uses and Benefits, Editor; Yamaguchi M, Nova Science Publishers, Inc., New York, USA, Chapter 8, pp.143-173, 2012
  15. Masayoshi Yamaguchi: Osteoporosis: Potent treatment with combination of functional food factors. In: Advances in Medicine and Biology. Volume 64, New York, USA, in press, 2013.
  16. Masayoshi Yamaguchi: Regucalcin, a suppressor protein in signal transduction. In: New Developments on    Signal Transduction Research. Editor; Yamaguchi M, Nova Science Publishers, Inc., New York, USA, pp.127-184, 2013.
  17. Masayoshi Yamaguchi: Dietary β-cryptoxanthin stimulates osteogenesis: Role in prevention and treatment of osteoporosis. In: Carotenoids: Food Sources, Production and Health    Benefits. Editor; Yamaguchi M, Nova Science Publishers, Inc., New York, USA,
    Chapter 16,pp.319-336, 2013.
  18. Masayoshi Yamaguchi: Biomedical Osteoporosis Treatment. Nova Science Publishers, Inc., New York, USA, 2013.
  19. Masayoshi Yamaguchi: Role of regucalcin in calcium signaling of kidney cells. In: New Development on Calcium Signaling Research.
    Nova Science Publishers, Inc., New York, USA, pp.-, 2014.
  20. Masayoshi Yamaguchi: Suppressive role of regucalcin in cell protein synthesis: Involvement in calcium signaling. In: New Development on Calcium Signaling Research. Nova Science Publishers, Inc., New York, USA, pp.-, 2014.

 

 

Masayoshi Yamaguchi

Professor

 

  • :1-404-727-2598
  • DEPARTMENTDepartment of Hematology and Biomedical Oncol
    Emory University School of Medicine
  • COUNTRY USA