leopoldo-spadea
Leopoldo Spadea, MD
Associate Clinical Professor of Ophthalmology

Department of Medico-Surgical Sciences and Biotechnologies
Sapienza University of Rome – Italy
Rome, Italy
E-mail: leopoldospadea@gmail.com

Education


Biography

Prof. Spadea is an associate clinical professor in ophthalmology, school of medicine, “Sapienza” University of Rome, Italy. Prof. Spadea has previously worked at the University of L'Aquila.
Prof. Spadea has presented papers at national and international congresses and symposiums and published 300 scientific papers in national and international journals (H-Index 15). In particular, having become an expert in refractive surgery, he has been called upon to present official papers in many different national and international courses and symposiums. Prof. Spadea is an expert on issues concerning corneal topography, excimer laser refractive procedures (PRK and LASIK) and keratoplasty.


Research Interest

His interest includes corneal topography, excimer laser refractive procedures (PRK and LASIK) and keratoplasty.


Scientific Activities

Honors and Awards
2014 “Best paper of the session” XXXII Congress of European Society of Cataract and Refractive Surgeons (ESCRS), London 13 - 17 September 2014 for the paper “Recovery of corneal sensitivity after epi-off and epi-on collagen cross-linking in keratoconus”
2009 President of the Italian Ophthalmological Sciences (AISO)
2008 Honorary Member of the Italian Society of Cornea Transplant (SITRAC)
2006 Founding Member of the Italian Academy Sciences Ophthalmology (AISO)
2005 Secretary of the Italian Society of Cornea Transplant (SITRAC)
2004 III "SOI Award 2004 Project Scientific Research", for the work "The pathophysiological basis of oxidative stress in the retina: new natural antioxidants", granted by the Board of Directors of the Italian Society of Ophthalmology (SOI)
2004 Board member of the Italian Society of Cornea Transplant (SITRAC)
2004 Member of the Executive Council of the Italian Association of Cataract and Refractive Surgery (AICCER)
2003 Founding Member of the Italian Association of Cataract and Refractive Surgery (AICCER)
2003 Regional Delegate for Abruzzo of the Italian Society of Ophthalmology (SOI)
2001 International Delegate of Italy for the Keratomileusis Study Group (KMSG)
1999. “Best Poster Prize – Refractive” al XVII Congress of European Society of Cataract and Refractive Surgeons, Wien 5-7 September 1999, for the paper “Effectiveness of LASIK to correct refractive error after penetrating keratoplasty”
1999 International Representative of Italy for the International Society of Refractive Surgery (ISRS) International Council (1999-2001; 2002-2004)

Publications

  1. “Steroids and neuroendocrine hormones detected by the immunoperoxidase technique from malignant melanomas and nevi of the choroid and conjunctiva” Di Tondo U., Balestrazzi E., Santeusanio G., Pintucci S., Spadea L. Ophthalmologica, 192, 1: 34-38, 1986
  2. “Reperti istopatologici in bulbi pseudofachici” Balestrazzi E., Blasi M.A., Caldarola A., Spadea L., Marullo M., Leopardi S. Proceedings II International Congress - International Association for Cataract Related Research (IACRR), Palermo, 16-19 October 1986, “Basic and clinical aspects of cataract”, 301-310, Ed. S.T.A.S.S., Palermo, 1988
  3. “La lensectomia via pars plana” Balestrazzi E., Marullo M., Spadea L., Sabetti L. Proceedings III Italian-Greek-Yugoslav E.N.T. Neuro-Ophthalmo Neurosurgery Congress, Rome, November 12-15 1986, 443-454, Ed. CIC Int., Rome, 1987
  4. “Retinopatia dei prematuri: possibilità attuali di terapia chirurgica” Balestrazzi E., Spadea L., Marullo M., Aschettino D. Proceedings III Italian-Greek-Yugoslav E.N.T. Neuro-Ophthalmo Neurosurgery Congress, Rome, November 12-15 1986, 217-227, Ed. CIC Int., Rome, 1987
  5. “Electrofunctional changes in the pseudoexfoliation syndrome” Spadea L., D'Andrea D., Sabetti L., Balestrazzi E.  New Trends in Ophthalmology, IV, 3: 233-240, 1989
  6. “Histopathology of epikeratoplasty”  Balestrazzi E., Blasi M.A., Marullo M., Spadea L. Proceedings 5th International Congress on Cataract and Refractive Surgery, Florence, June 19-21 1989, 263-264, Cappelli Editore, 1991
  7. “Cataract and implantology in myopic eyes” Balestrazzi E., Blasi M.A., Spadea L., Marullo M. Proceedings 5th International Congress on Cataract and Refractive Surgery,  Florence, June 19-21 1989, 145-147, Cappelli Editore, 1991
  8. “Malignant conjunctival epibulbar fibrous histiocytoma with orbital invasion” Balestrazzi E., Ventura T., Delle Noci N., Blasi M.A., Spadea L., Coletti G. European Journal of Ophthalmology, 1: 23-27, 1991
  9. “Problemi chirurgici della cataratta complicata ad iridociclite eterocromica ipertensiva di Fuchs” Balestrazzi E., Blasi M.A., Spadea L., Marullo M. Proceedings V International Congress - International Association for Cataract Related Research (IACRR), Rome, November 17-19 1989, Eds F. Ponte, G. Giuffrè  “Cataract Associated with Ocular and Systemic Disease”, Medical Books, 47-50, Palermo, 1991
  10. “Istologia dei tumori metastatici” Balestrazzi E., Blasi M.A., Delle Noci N., Spadea L., Pomes L., Iaculli C. Proceedings International Symposium on Intraocular Tumors, Florence, February 2-4 1990, Ed. Medical Books, 85-89, Palermo, 1991
  11. “Evaluation of electrofunctional data following Argon laser trabeculoplasty in primary open angle glaucoma” Spadea L., D'Andrea D., Blasi M.A., Balestrazzi E.  Graefe's Archive for Clinical and Experimental Ophthalmology, 29: 414-417, 1991
  12. “Excimer laser photorefractive keratectomy: histological, immunohistochemical and ultrastructural study on human corneas” Balestrazzi E., De Molfetta V., Spadea L., Vinciguerra P., Sabetti L., Palmieri G., Santeusanio G., Spagnoli G. Italian Journal of Ophthalmology, VI, 2: 95-100, 1992
  13. “Histological, immunohistochemical and ultrastructural findings following photorefractive keratectomy with excimer laser on human corneas” Balestrazzi E., Spadea L., Vinciguerra P., Sabetti L., Palmieri G.P. Proceedings XXII E.C.L.S.O. Congress “The role of contactology and refractive surgery in ophthalmology”, Rome, June 4-7 1992, 187-193, Ed. Monduzzi, Bologna, 1993
  14. “Pathology of ocular disease associated with pseudoexfoliation syndrome” Balestrazzi E., Blasi M.A., Spadea L., Di Staso S., Balestrazzi A. New Trends in Ophthalmology, VIII, 3, 151-155, 1993
  15. “Effect of centering excimer laser PRK on refractive results: a corneal topography study” Spadea L., Sabetti L., Balestrazzi E. Journal of Refractive and Corneal Surgery, Vol. 9, 2: S22-25, 1993
  16. “Electrooculographic changes following local excision of uveal melanoma” Spadea L., D'Amico M., Dragani T., Balestrazzi E. Documenta Ophthalmologica, 86: 239-245, 1994
  17. “Electroretinographyc findings in congenital ocular motor apraxia (Cogan syndrome)” Magni R., Spadea L., Pece A., Durante A., Mansutti L., Brancato R. Documenta Ophthalmologica, 86: 259-266, 1994
  18. “Long term changes secondary to blunt bulbar traumas: electrofunctional study” Spadea L., Balestrazzi E.  Ocular Surgery News International Edition, 33 and 42, February 1994
  19. “Electrooculographic changes in patients affected by ocular tumors” Spadea L., Magni R., Rinaldi G., Sorce R., Ponte F., Brancato R., Balestrazzi E., Ravalico G. Proceedings International Symposium on Intraocular and Epibulbar Tumors, Florence March 3-5 1994, Monduzzi Ed., Bologna, 219-222, 1994
  20. “Corneo-conjunctival carcinoma in situ: surgery treatment with corneal lamella graft” Spadea L., Blasi M.A., Bianco G., Balestrazzi E. Proceedings International Symposium on Intraocular and Epibulbar Tumors, Florence March 3-5 1994, Monduzzi Ed., Bologna, 239-242, 1994
  21. “Measurement of corneal thickness by ultrasound after photorefractive keratectomy in high myopia” Sabetti L., Spadea L., Furcese N., Balestrazzi E. Journal of Refractive and Corneal Surgery, Vol. 10, 2: S211-216, 1994
  22. “Histological, immunohistochemical and ultrastructural findings in human corneas after photorefractive keratectomy” Balestrazzi E., De Molfetta V., Spadea L., Vinciguerra P., Palmieri G.P., Santeusanio G., Spagnoli L. Journal of Refractive Surgery, Vol. 11, 3: 181-187, 1995
  23. “Local excision of retinal metastasis from cutaneous melanoma” Balestrazzi E., Blasi M.A., Marullo M., Greco I.M., Spadea L. European Journal of Ophthalmology, 5: 149-154, 1995
  24. “PERG and P-VEP after surgical trabeculectomy in primary open angle glaucoma” Spadea L., Giuffrè I., Bianco G., Balestrazzi E. European Journal of Ophthalmology, 2: 92-95, 1995
  25. “Specular microscopy of the corneal endothelium after excimer laser photorefractive keratectomy” Spadea L., Dragani T., Blasi M.A., Mastrofini M.C., Balestrazzi E. Journal of Cataract and Refractive Surgery, Vol. 22: 188-193, 1996
  26. “Penetrating keratoplasty with donor and recipient corneas of the same diameter” Spadea L., Bianco G., Mastrofini M.C., Balestrazzi E. Ophthalmic Surgery and Lasers, Vol. 27, 6: 425-430, 1996
  27. “Effect of myopic excimer laser photorefractive keratectomy on electrophysiologic function of the retina and optic nerve” Spadea L., Dragani T., Magni R., Rinaldi G., Balestrazzi E. Journal of Cataract and Refractive Surgery, Vol. 22: 906-909, 1996
  28. “Four techniques for retreatment after excimer laser photorefractive keratectomy” Spadea L., Bianco G., Balestrazzi E. Journal of Refractive Surgery, Vol. 12, 6: 693-696, 1996
  29. “Early detection of P-VEPs and PERGs changes in ophthalmic Graves' disease” Spadea L., Bianco G., Dragani T., Balestrazzi E. Graefe's Archive for Clinical and Experimental Ophthalmology, August, 235: 501-505, 1997
  30. “Modification des examens electrofonctionnels dans le syndrome pseudo-exfoliatif” Spadea L., Giuffrè I., Bianco G., Karounne M. Journal Francais d’Ophtalmologie, 20, 8: 599-603, 1997
  31. “Unilateral retinitis pigmentosa: clinical and electrofunctional report of four cases” Spadea L., Magni R., Rinaldi G., Dragani T., Bianco G. Ophthalmologica, 212: 350-354, 1998
  32. “Long term results of excimer laser photorefractive keratectomy in high myopia: a preliminary report” Spadea L., Colucci S., Bianco G., Balestrazzi E. Ophthalmic Surgery and Lasers, Vol. 29, 6: 490–496, 1998
  33. “Videokeratographic changes after excimer laser in situ keratomileusis for correction of high myopia” Spadea L., Bianco G., Masini M.C., Balestrazzi E. Journal of Cataract and Refractive Surgery, Vol. 25/12: 1589-1595, 1999
  34. “Normal EOG values in intraretinal metastasis from cutaneous melanoma: a case report” Spadea L., Bisti S., Colucci S., Balestrazzi E. Documenta Ophthalmologica, Vol. 96, 4: 305-309, 1999
  35. “Effectiveness of LASIK to correct refractive error after penetrating keratoplasty” Spadea L., Mosca L., Balestrazzi E. Ophthalmic Surgery and Lasers, Vol. 31, N.2: 111-120, 2000
  36. “Role of the corneal epithelium in refractive changes following laser in situ keratomileusis for high myopia“ Spadea L., Fasciani R., Necozione S., Balestrazzi E. Journal of Refractive Surgery, Vol. 16, N.2: 133-139, 2000
  37. “Triple procedure with phacoemulsification before trephination” Balestrazzi E., Spadea L., Mosca L. In: “The Art of Phacoemulsification”, Ed. K.R. Metha, J.J. Alpar, Jaypee Brothers Medical Publisher (P) LTD, New Delhi, 462-470, 2000
  38. “Treatment of vascular retinopathies with Pycnogenol ((R))” Spadea L., Balestrazzi E. Phytotherapy Research, Vol. 15, N. 3: 219-23, 2001
  39. “The corneal endothelium after excimer laser in situ keratomileusis for correction of high myopia” Spadea L., Bianco G. Ocular Surgery News, Vol. 19, N. 17: 12-17, 2001
  40. “Long-term results of penetrating keratoplasty using a single or double running suture technique” Spadea L., Bianco G., Cifariello F., Balestrazzi E. Graefe's Archive for Clinical and Experimental Ophthalmology, May; Vol. 240, N. 5: 415-9, 2002
  41. “Flap measurements with Hansatome microkeratome” Spadea L., Cerrone L., Necozione S., Balestrazzi E. Journal of Refractive Surgery, Vol. 18, N. 2: 149-154, 2002
  42. “Iatrogenic keratectasia following laser in situ keratomileusis“ Spadea L., Palmieri G.P., Mosca L., Fasciani R., Balestrazzi E. Journal of Refractive Surgery, Vol. 18, N. 4: 475-480, 2002
  43. “Lasik for the correction of refractive error after penetrating keratoplasty” Balestrazzi E., Spadea L., Mosca L., Fasciani R. In: “Textbook of Ophthalmology”, Ed. S. Agarwal et al, Jaypee Brothers Medical Publisher (P) LTD, New Delhi, Vol. 2: 1231-1239, 2002
  44. “Correlation between ERG changes and FGF2 mRNA upregulation in patients affected by choroidal melanoma”  Di Loreto S., Spadea L., Cencioni S., Balestrazzi E., Adorno D., Cervetto L., Bisti S. Experimenta Eye Research, Vol. 75, N. 2: 217-225, 2002
  45. “Electro-oculographic abnormality in eyes with uveal melanoma” Spadea L., Bianco G., Magni R., Rinaldi G., Ponte F., Brancato R., Ravalico G., Balestrazzi E. European Journal of Ophthalmology, Vol. 12, N. 5: 419-423, 2002
  46. “Excimer laser phototherapeutic keratectomy in intraepithelial corneo-conjunctival carcinoma” Spadea L., Petrucci R., Balestrazzi E. Journal of Cataract and Refractive Surgery, Vol. 28, N. 11: 2062-2064, 2002
  47. “Choroidal neovascolarization after laser-assisted in situ keratomileusis following penetrating keratoplasty” Scupola A., Mosca L., Balestrazzi A., Tiberti A. & Spadea L. Graefe's Archive for Clinical and Experimental Ophthalmology, August, Vol. 241, N. 8: 682-4, 2003
  48. “Topographically guided excimer laser photorefractive keratectomy to treat superficial corneal opacities” Spadea L., Bianco G., Balestrazzi E. Ophthalmology, Vol. 111, N. 3: 458-462, 2004
  49. “A suture technique to manage a case of severe early flap displacement after laser in situ keratomileusis” Spadea L., Pantaleoni P., Bianco G. British Journal of Ophthalmology, Video Report, Volume 88, Number 7, July 2004 <<http://bjo.bmjjournals.com/cgi/content/full/88/7/DC1/1>>
  50. "Pre-excimer laser and post-excimer laser refractive surgery measurements of scotopic pupil diameter using 2 pupillometers" Spadea L., Giammaria D., Ferrante R., Balestrazzi E. Ophthalmology, Vol. 112, N. 6: 1003-1008, 2005
  51. “Photorefractive keratectomy and laser in situ keratomileusis in refractive accommodative esotropia” Sabetti L., Spadea L., D’Alessandri L., Balestrazzi E. Journal of Cataract and Refractive Surgery, Vol. 31, N. 10: 1899-1903, 2005
  52. “Enhancement outcomes after photorefractive keratectomy and laser in situ keratomileusis using topographically guided excimer laser photoablation” Spadea L., Di Gregorio A. Journal of Cataract and Refractive Surgery, Vol. 31, N. 12: 2306-2312, 2005
  53. “Photorefractive keratectomy and LASIK for the correction of hyperopia: 2-year follow up” Spadea L., Sabetti L., D’Alessandri L., Balestrazzi E. Journal of Refractive Surgery, Vol. 22, N. 2: 131-136, 2006
  54. “The CORTES study: corneal transplant indications and graft survival in an Italian cohort of patients (CORneal Transplant Epidemiological Study)” Fasolo A., Frigo A.C., Böhm E., Genisi C., Rama P., Spadea L., Mastropirro B., Fornea M., Ponzin D., Grigoletto F. Cornea, Vol. 25, N. 5: 507-515, 2006
  55. “No alcohol LASEK vs PRK: a comparative study” Spadea L., Fiasca A. In: “Refractive Surface Ablation: PRK, LASEK, Epi-LASEK, Custom, PTK, and Retreatment”, Ed. P. Vinciguerra, Slack Inc. Thorofare (NJ) USA, Chapter 23, 201-206, 2006
  56. “Topographically guided trans-epithelial PRK for refractive and therapeutic purpose” Spadea L., Di Gregorio A. In: “Refractive Surface Ablation: PRK, LASEK, Epi-LASEK, Custom, PTK, and Retreatment”, Ed. P. Vinciguerra, Slack Inc. Thorofare (NJ) USA, Chapter 14, 135-144, 2006
  57. “Topographically guided LASIK” Spadea L., Mosca L. Ophthalmology, Vol. 113, N. 7: 1251-1252.e1-2, 2006
  58. “Comparison of optical low coherence reflectometry and ultrasound pachymetry in the measurement of central corneal thickness before and after photorefractive keratectomy” Spadea L., Giammaria D., Fiasca A., Di Genova L. Journal of Refractive Surgery, Vol. 23, N. 7: 661-666, 2007
  59. “Three different techniques for photorefractive keratectomy for mixed astigmatism” Spadea L., D’Alessandri L., Necozione S., Balestrazzi E. Ophthalmic Surgery Lasers & Imaging, Vol. 38, 307- 313, 2007
  60. “Excimer laser customized ablation: surgical technique, indications, results” Spadea L., Fiasca A., Verrecchia V In: “Video Atlas of Lamellar Keratoplasty”, Ed. L. Fontana, G. Tassinari, Fabiano Editore (Milano), 89-98, 2007
  61. “Why I still use the microkeratome” Spadea L., Di Gregorio A., Garofano G. Cataract & Refractive Surgery Today Europe, Vol. November/December, 52-53, 2007
  62. “Clinical effectiveness of Pycnogenol in ocular vascular retinopathies” Spadea L., Viola M., Viola G., Bisti S. In: “Natural Products as Future Medicinal Agents, Ed. Transworld Research Network, Kerala, India, 93-113, 2008
  63. “Regression of Urrets-Zavalia syndrome after deep lamellar keratoplasty for keratoconus: A case study” Spadea L., Viola M., Viola G. The Open Ophthalmology Journal, Vol. 2, 130-131, 2008
  64. “Residual  astigmatism after corneal ablation” Spadea L. Cataract & Refractive Surgery Today Europe, Vol. October, 72-74, 2008
  65. “Excimer laser-assisted lamellar keratoplasty for the surgical treatment of keratoconus” Spadea L., Giammaria D., Fiasca A., Verrecchia V. Journal of Cataract and Refractive Surgery, Vol. 35, N. 1: 105-112, 2009
  66. “Laser correction of myopia” Spadea L., Di Genova L. In: “Eye Infections, Blindness and Myopia”, Ed. J. Higgins and D. Truax, Nova Biomedical, Chapter 6, 165-195, 2009
  67. “Topographically guided two steps LASIK and standard LASIK in the correction of refractive errors after penetrating keratoplasty” Spadea L., Saviano B.M., Di Gregorio A., Di Lodovico D., De Sanctis F. European Journal of Ophthalmology, Vol. 19, N. 4: 535 – 543, 2009
  68. “New and future treatments - excimer laser lamellar keratoplasty and advanced cross-linking” Spadea L., Devore D.P., Eiferman R.A., Dewoolfson B., Stewart C.Wm., Swartz T. and Wang M. In: “Keratoconus & Keratoectasia: Prevention, Diagnosis, and Treatment”, Ed. Wang M., SLACK Incorporated, Chapter 18, 169–177, 2009
  69. "Anti-vascular endothelial growth factor activity in the bevacizumab and triamcinolone acetonide combination for intravitreal use" Giammaria D., Cinque B., Di Lodovico D., Savastano M.C., Cifone M.G., Spadea L. European Journal of Ophthalmology. Vol. 19, N. 5:842-847, 2009
  70. "Agreement between two OCT systems" Giammaria D., Spadea L. Investigative Ophthalmology and Visual Science Online, Electronic Letter, 16 March 2009 <<http://www.iovs.org/cgi/eletters/49/10/4290#8792>>
  71. “Lamellar keratoplasty with the excimer laser ” Spadea L. Cataract & Refractive Surgery Today Europe, Vol. July/August, 29-32, 2009
  72. “Corneal collagen cross-linking with riboflavin and UVA irradiation in pellucid marginal degeneration” Spadea L. Journal of Refractive Surgery, Vol. 26, N. 5: 375-377, 2010
  73. “Intraoperative videokeratography in penetrating keratoplasty and excimer laser-assisted lamellar keratoplasty for keratoconus” Spadea L., Fiasca A., Federici S. Journal of Refractive Surgery, Vol. 26, N. 9, 660-668, 2010
  74. “Corneal collagen cross-linking” Spadea L., Mencucci R. Ophthalmology, Vol. 118, N. 12: 2520.e1-4, 2011
  75. “Effectiveness of scraping and mitomycin C to treat haze after myopic PRK” Spadea L., Verrecchia V. The Open Ophthalmology Journal, Vol. 5, 63-65, 2011
  76. “Collagen crosslinking for ectasia following PRK performed in excimer-laser-assisted keratoplasty for keratoconus” Spadea L. European Journal of Ophthalmology, Vol. 22, N. 2: 274-277, 2012
  77. “Effectiveness of scraping and mitomycin C to treat haze after myopic photorefractive keratectomy” Spadea L. Ocular Times, Vol. 2, N. 3, 36-37, 2012
  78. “Optical pachimetry-guided customized excimer laser-assisted lamellar keratoplasty for the surgical treatment of keratoconus” Spadea L., Gizzi R, Evangelista Conocchia N., Urbano S. Journal Cataract Refractive Surgery, Vol. 38, N. 9, 1559-1567, 2012
  79. “Treatment of post-operative endophtalmitis” Spadea L., Fiasca A. European Ophthalmic Review, Vol. 6, N. 3, 149–156, 2012           
  80. “Refractive surgery in diabetic patients: a review of the literature” Spadea L., Paroli M.P. Clinical Ophthalmology, Vol. 6, 1775-1783, 2012                
  81. “Transepithelial corneal collagen cross-linking in ultrathin keratoconic corneas”  Spadea L., Mencucci R. Clinical Ophthalmology, Vol. 6, 1785-1792, 2012
  82. “Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus” Spadea L., Paroli M.Clinical Ophthalmology, Vol. 6, 1793-1800, 2012      
  83. “Corneal ectasia after myopic laser in situ keratomileusis: a long term study” Spadea L., Cantera E., Cortes M., Evangelista Conocchia N., Stewart C.W. Clinical Ophthalmology, Vol. 6, 1801-1813, 2012
  84. “Hyperopia treatments” Spadea L.Cataract & Refractive Surgery Today Europe, Vol. 8, N. 1, 60-62, 2013
  85. “The ideal ablation pattern for combined treatments: CXL plus PRK” Spadea L. Cataract & Refractive Surgery Today Europe, Vol. 8, N. 3, 49-51, 2013     
  86. “Astigmatism correction with toric intraocular lenses: wavefront aberrometry and quality of life”   Mencucci R., Giordano C., Favuzza E., Gicquel J.J., Spadea L., Menchini U.                British Journal of Ophthalmology, Vol. 97, N. 5, 578-582, 2013
  87. “Severe macular edema in patients with juvenile idiophatic arthritis related uveitis” Paroli M.P., Fabiani C., Spinucci G., Abicca I., Sapia A., Spadea L.              Case Reports in Ophthalmological Medicine, Vol. 2013, Article ID 803989, 5 pages, 2013
  88. “Biological parameters determining the clinical outcome of autologous cultures of limbal stem cells” Pellegrini G., Rama P., Matuska S., Lambiase A., Bonini S., Pocobelli A., Colabelli R.G., Spadea L., Fasciani R., Balestrazzi E., Vinciguerra P., Rosetta P., Tortori A., Nardi M., Gabbriellini G., Traverso C.E., Macaluso C., Losi L., Percesepe A., Venturi B., Corradini F., Panaras A., Di Rocco A., Guatelli P., De Luca M.Regenerative Medicine, Vol. 8, N. 5, 553-567, 2013
  89. “Visual rehabilitation in patients with myopic maculopathy: our experience” Vingolo E.M., Salvatore S., Domanico D., Spadea L., Nebbioso M. Canadian Journal of Ophthalmology, Vol. 4, N. 5, 438-442, 2013
  90. “Corneal sensitivity in keratoconus: a review of the literature” Spadea L., Salvatore S., Vingolo E.M. The Scientific World Journal, Vol. 2013, Article ID 683090, 7 pages, 2013
  91. “Corneal collagen cross-linking for keratectasia after laser in situ keratomileusis: a review of the literature”                 Spadea L., Verboschi F., Valente S., Vingolo E.M. The International Journal of Keratoconus and Ectatic Corneal Diseases, Vol. 2, N. 3, 113-120, 2013
  92. “Treatment of post-operative endophthalmitis” Spadea L. US Ophthalmic Review, 7, Vol. 2, 146–153, 2014             
  93. “Microincision vitrectomy surgery in vitreo-macular traction syndrome of retinitis pigmentosa patients” Vingolo E.M., Valente S., Gerace E., Spadea L., Nebbioso M.               Journal of Biomedicine and Biotechnology (BioMed Research International), vol. 2014, Article ID 537081, 7 pages, 2014
  94. “Cystic Fibrosis: new trends by ophthalmological evaluation”  Nebbioso M., Quattrucci S., Leggieri E., Spadea L., Vingolo E.M.                Journal of Biomedicine and Biotechnology (BioMed Research International), vol. 2014, Article ID 580373, 5 pages, 2014
  95. “Post-operative endophthalmitis caused by Acremonium falciforme with orbital and extra-orbital involvement following combined cataract and glaucoma surgery: a case report” Cagini C., Iannone A., Fiore T., Lupidi M., Spadea L.Journal of Medical Case Reports, Vol. 8, 373, 5 pages, 2014
  96. “Recovery of corneal sensitivity after collagen crosslinking with and without epithelial debridement in eyes with keratoconus” Spadea L., Salvatore S., Paroli M.P., Vingolo E.M.  Journal Cataract Refractive Surgery, Vol. 41, N. 3, 527-532, 2015
  97. “Aspergillus flavus endophthalmitis after penetrating keratoplasty combined with cataract phacoemulsification and IOL implantation: a case report” Spadea L., Abbouda A., Albicca I., Paroli M.P.      The International Journal of Clinical Ophthalmology and Visual Sciences, Vol. 35, 145-148, 2015
  98. “Long term results of no-alcohol laser epithelial keratomileusis (LASEK) and photorefractive keratectomy (PRK) for myopia” Spadea L., Verboschi F., De Rosa V., Salomone M., Vingolo E.M. International Journal of Ophthalmology, Vol. 8, 3, ID 15‐3‐19, 2015   
  99. “Macular hole in retinitis pigmentosa patients: microincision vitrectomy with polydimethylsiloxane (PDMS) as possible treatment" Nebbioso M., Vingolo E.M., Valente S., Gerace E., Spadea L. Eye (Lond), Vol. 29, 5, 699-702, 2015
  100. "Ocular manifestations of Ebola virus disease. An ophthalmologist’s guide to prevent infection and panic" Vingolo E.M., Messano G., Spadea L., Fragiotta S., Petti S. Journal of Biomedicine and Biotechnology (BioMed Research International) Vol. 2015, Article ID 487073, 7 pages, 2015
  101. “Corneal collagen cross-linking followed by phacoemulsification with IOL implantation for progressive keratoconus associated with high-myopia and cataract”        Spadea L., Salvatore S., Verboschi F., Vingolo E.M. The International Journal of Clinical Ophthalmology and Visual Sciences, Vol Oct 35, 5, 727-731, 2015.
  102. “Posterior corneal surface stability after femtosecond laser-assisted keratomileusis” Cagini C., Messina M., Fiore T., Lupidi M., Fruttini D., Spadea L. Journal of Ophthalmology, Vol. 2015, Article ID 184850, 6 pages, 2015.
  103. “Anterior lamellar keratoplasty in keratoconus”Spadea L. Journal of Eye & Cataract Surgery, Vol. 1 No. 1: 6, 1-3, 2015
  104. “Postoperative endophthalmitis: prevention and treatment” Spadea L., Tonti E., Anselmucci F. In “Endophatlmitis”, Ed. Cole B., Nova Science Publishers, Inc., 37-66, 2015 
  105. “Sliding keratoplasty followed by transepithelial iontophoresis collagen cross-linking for pellucid marginal degeneration” Spadea L., Maraone G., Cagini C. Journal of Refractive Surgery, Vol. 1; N. 32(1), 47-50, 2016
  106. “Corneal wound healing after laser vision correction” Spadea L., Giammaria D., Trabucco P. British Journal of Ophthalmology, Vol. 100, N. 1, 28-33, 2016. Published Online First: 24 September 2015 
  107. “Current techniques of lamellar keratoplasty for keratoconus”                Spadea L., De Rosa V.       Saudi Medical Journal, Vol. 37, 2, 179-188, 2016 
  108. “The effect of corneal light scatter on vision: a review of the literature” Spadea L., Maraone G., Verboschi F., Vingolo E.M., Tognetto D. International Journal of Ophthalmology, Vol. 9, 3, ID 16‐3‐13, 2016
  109. “Anterior corneal surface irregularity after Descemet-stripping endothelial keratoplasty for bullous keratopathy”      Spadea L., Santamaria V., Vingolo E.M., Cagini C. European Journal of Ophthalmology, Vol. Apr 12; N. 26 (3), 209-215, 2016. Published Online First: 6 November 2015              
  110. “Visual recovery after primary retinal detachment surgery: biofeedback rehabilitative strategy” Vingolo E.M., Fragiotta S., Domanico D., Limoli P.G., Nebbioso M., Spadea L.               Journal of Ophthalmology, Vol. 2016, Article ID 8092396, 5 pages, 2016            
  111. "Fixation improvement through biofeedback rehabilitation in Stargardt disease" Scuderi G.L., Verboschi F., Domanico D., Spadea L. Case Reports in Medicine, Vol. 2016, Article 4264829, 4 pages, 2016
  112. “Canaloplasty: current value in the management of glaucoma”              Cagini C., Peruzzi C., Fiore T., Spadea L., Lippera M., Lippera S. Journal of Ophthalmology, Vol. 2016, Article ID7080475, 6 pages, 2016
  113. “Corneal stromal demarcation line after collagen-crosslinking in corneal ectatic diseases: a review of the literature” Spadea L., Tonti E., Vingolo E.M. Clinical Ophthalmology, Vol. 10, 1803–1810, 2016
  114. “Spontaneous resolution of vitreomacular traction in a patient with a macular hole in the fellow eye”  Spadea L., Verboschi F., Cagini C., S. Cillino ARC Journal of Ophthalmology, Vol. 1, 1, 19-22, 2016
  115. “A case of unilateral circumscribed posterior keratoconus evaluated by three different imaging tools: optical coherence tomography, videokeratography and Scheimpflug corneal tomography” Spadea L., Maraone G., Cagini C. The International Journal of Clinical Ophthalmology and Visual Sciences, Vol. 37, 1, 279-283, 2017
  116. “Aqueous humor antimicrobial activity: in vitro analysis after topical 0.5% chloramphenicol application” Cagini C., Dragoni A., Orsolini G., Fiore T., Beccasio A., Spadea L., Moretti A., Mencacci A. Current Eye Research, Jan 13:1-5, 2017 doi: 10.1080/02713683.2016.1256414.

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