Education

Biography

Professor Abel Vieira is born in Lisbon, Portugal, in 1951. He obtained his Graduation in Chemical Engineering in 1974 at Instituto Superior Técnico (Lisbon), his PhD in Chemistry in 1988 at Universidade Técnica de Lisboa and his Habilitation in Chemistry, speciality Organic Chemistry in 2011 at Universidade Nova de Lisboa. In both Universities he has been professor of several disciplines in the area of Organic Chemistry. His main research interests are in the area of Physical Organic Chemistry, Radical Chemistry and Radiation Chemistry. He integrates a research group in Green Chemistry at Universidade Nova de Lisboa – LAQV-REQUIMTE – where he runs his own research group (Oxidative stress and Antioxidants) and keeps several collaborations with other portuguese and foreign groups, mainly in France and Germany. He supervised several PhD and Post-Doc students, is a referee of international peer reviewed journals and member of Scientific Societies, such as the Portuguese Chemical Society, where he was the head of the Free Radicals Group. He participated in / organized national and international scientific conferences, was a member of a European COST Action and published in high IF journals (see list of publications). Professor Vieira, besides his mother language, Portuguese, is fluent in French, German and English.

Research Interest

• Physical Organic Chemistry
• Radical Chemistry and Radiation Chemistry
• Generation of free radicals by radiomimetic (chemical and photochemical) methods
• Gamma Radiolysis and electron Pulse-Radiolysis
• Characterization of transient radicals by ESR spectroscopy
• Identification of final stable products by HPLC/GC-MS techniques
• Oxidative stress studies
• Development of new antioxidants for protection of biological targets against oxidative damage
• Establishment of radical reaction mechanisms and
• Theoretical calculations.

Scientific Activities

Awards

• Appointed by the students as one of the three most outstanding graduation Professors at IST (1994/95) and Theoretical classes of Organic Chemistry for Environmental Engineering

SCIENTIFIC ASSOCIATIONS

• Member of the Portuguese Chemical Society - SPQ (Divisions of Organic Chemistry and Physical Chemistry, Group of Free Radicals; President of the Group of Free Radicals, 1992-93, 1997-99 and since 2001)
• Member of the Old Grant Students Association of “Deutscher Akademischer Austauschdienst” (Portuguese-German Association).

OTHER ACTIVITIES

• Delegate of the Chemistry Assistants at the Pedagogic Council (1979-1981)
• Vice-President of the Pedagogic Council (1980-1981)
• Member of the Assembly of Representatives (1983)
• Delegate of the Organic Chemistry Division at the Pedagogic Committee of the Chemical Engineering Department (1991-1993)
• Delegate of the Professors of the Chemical Engineering Department at the Pedagogic Council (1993-2000)
• Member of the Coordinating Committee of the Pedagogic Council (1993-1997)
• Delegate Professor at the Executive Committee of the Pedagogic Council (1993-1997)
• Delegate of IST at UTL Senate (1993-1997)
• Coordinator of the Chemical Engineering Graduation and, inherently, President of the Pedagogic Committee of the Chemical Engineering Department (1993)
• Coordinator of the 2nd year of the Chemical Engineering Graduation and, inherently, member of the Coordinating and Pedagogic Committees (1993-200)
• Coordinator of the 2nd year of the Chemistry and Biologic Engineering Graduations and, inherently, member of the Coordinating and Pedagogic Committees (1998-200)
• Member of the Senate of the Scientific Council (1993-1995)
• President of the Jury of AD-HOC Examinations (1994-1999)
• Member of the Assembly of Representatives (2000-2008)
• Coordinator of the Discipline Group of Fundamental and Bioorganic Organic Chemistry (2003-2008)

Publications

1. VIEIRA, A.J.S.C.; HEROLD, B.J. “Estudo Preliminar do Resíduo Encontrado nos Tubos de Escape dos Autoclaves de Fabricação de Aglomerado Negro de Cortiça”, Bol. Inst. Prod. Florestais (1976), 457, 1
2. PORTELA, M.F.; RIBEIRO, F.R.; PIRES, M.J.; OLIVEIRA, M.M.; VIEIRA, A.J.S.C. “Investigação Universitária no Sector Químico: Suas Finalidades, Organização e Problemas”, Técnica (1981), 462/463, 160
3. PIRES, M.J.; RIBEIRO, F.R.; VIEIRA, A.J.S.C.; OLIVEIRA, M.M.; FREIRE, F.G. “A Catálise no Combate à Poluição pelos Gases de Escape dos Automóveis”, Engenharia, Ciências e Técnicas (1983), 7, 31
4. VIEIRA, A.J.S.C. “Radicais Oxidantes: da Química à Biologia”, Química – Bol. Soc. Port. Quim (2006), 100, 66-71
5. VIEIRA, A.J.S.C.; STEENKEN, S. “Pattern of OH Radical Reaction with 6- and 9-Substituted Purines. Effect of Substituents on the Rates and Activation Parameters of the Unimolecular Transformation of Two Isomeric Adducts”, J. Phys. Chem. (1987), 91, 4138 IF: 3,045; Cit: 75; DOI: 10.1021/j100299a039
6. VIEIRA, A.J.S.C.; STEENKEN, S. “Pattern of OH Radical Reaction with N6,N6-Dimethyladenosine. Production of Three Isomeric OH Adducts and their Dehydration and Ring-Opening Reactions”, J. Am. Chem. Soc. (1987), 109, 7441 IF: 4,318; Cit: 62; DOI: 10.1021/ja00258a031
7. VIEIRA, A.J.S.C.; STEENKEN, S. “Pattern of OH Radical Reaction with Adenine and its Nucleosides and Nucleotides. Characterization of Two Types of Isomeric OH Adduct and their Unimolecular Transformation Reactions”, J. Am. Chem. Soc. (1990), 112, 6986       IF: 4,463; Cit: 79; DOI: 10.1021/ja00175a036
8. VIEIRA, A.J.S.C.; STEENKEN, S. “Pattern of OH Radical Reaction with N6,N6,9-Trimethyladenine. Dehydration and Ring-Opening of Isomeric OH Adducts”, J. Phys. Chem. (1991), 95, 9340 IF: 3,144; Cit: 14; DOI: 10.1021/j100176a056
9. VIEIRA, A.J.S.C.; CANDEIAS, L.P.; STEENKEN, S. "Hydroxyl Radical Induced Damage to the Purine Bases of DNA: in vitro Studies", J. Chim. Phys. P. C. B. (1993), 90, 881 IF: 0,621; Cit: 22
10.  DIAS, R.M.B.; VIEIRA, A.J.S.C. "Hydroxylation de l’Adénine et ses Dérivés par des Agents  Radiomimétiques", J. Chim. Phys. P. C. B. (1993), 90, 899 IF: 0,621; Cit: 4
11.  SHOHOJI, M.C.; NOVAIS. H.M.; VIEIRA, A.J.S.C. "Electron Spin Resonance Study of the Reaction of SO4•− with Azolinones", J. Chem. Soc. Perkin Trans. 2 (1995), 2101 IF: 1,678; Cit: 1; DOI: 10.1039/P29950002101
12.  VIEIRA, A.J.S.C.; STEENKEN, S. "Radical Oxidation of Xanthines: A Reaction Pathway to Uric Acid?", J. Chim. Phys. P. C. B.  (1996), 93, 235  IF: 0,517; Cit: 10
13.  LANGMAN, S.; SHOHOJI, M.C.; TELO, J.P.; VIEIRA, A.J.S.C.; NOVAIS, H.M. “EPR Spectroscopic Study of the Radical Oxidation of Hydroxypurines in Aqueous Solution: Acid-Base Properties of the Derived Radicals”, J. Chem. Soc. Perkin Trans. 2 (1996), 1461        IF: 1,929; Cit: 5; DOI: 10.1039/P29960001461
14.  DIAS, R.M.B.; VIEIRA, A.J.S.C. “Structure and Redox Properties of One-Electron Oxidized Radicals from Adenine and Derivatives”, Redox Report (1996), 2(4), 279 IF: 0,893; Cit: 2
15.  VIEIRA, A.J.S.C.; TELO, J.P.; DIAS, R.M.B. "Reaction of Purines with Hydroxyl Radical Generated by Photolysis of Mercaptopyridine-N-oxides", J. Chim. Phys. P. C. B. (1997), 94, 318 IF: 0,700; Cit: 10
16. DIAS, R.M.B.; VIEIRA, A.J.S.C. "Effect of Oxygen on the Hydroxylation of Adenine by Photolytically Generated Hydroxyl Radical", J. Photochem. Photobiol. A (1997), 109 (2), 133 IF: 1,056; Cit: 3; DOI: 10.1016/S1010-6030(97)00120-2
17. TELO, J.P.; VIEIRA, A.J.S.C. “Mechanism of Free Radical Oxidation of Caffeine in Aqueous Solution”, J. Chem. Soc. Perkin Trans. 2 (1997), 1755        IF: 1,845; Cit: 12; DOI: 10.1039/a700944e
18. VIEIRA, A.J.S.C.; TELO, J.P. "EPR Detection of Oxygen Radical Anion in Aqueous Solution at Room Temperature", Redox Report (1997), 3, 303 IF: 1,196; Cit: 0DIAS, R.M.B.;
19. VIEIRA, A.J.S.C. "Substituent Effect on Superoxide Elimination from Peroxyl Radicals of Adenine and Methylated Derivatives", J. Photochem. Photobiol. A (1998), 117, 217          IF: 0,947; Cit: 2; DOI: 10.1016/S1010-6030(98)00347-5
20. VIEIRA, A.J.S.C.; TELO, J.P.; PEREIRA, H.F.; PATROCÍNIO, P.F.; DIAS, R.M.B. "Antioxidant Effect of Naturally Occurring Xanthines on the Oxidative Damage of DNA Bases", J. Chim. Pys. P. C. B. (1999), 96, 116-123 IF: 0,508; Cit: 4
21. STEENKEN, S.; VIEIRA, A.J.S.C. “Water Assisted Intramolecular Electron Transfer from the Ring to Side Chain in N,N,N’,N’-Tetraalkyl-para-phenylenediamine Radicals – The Reverse of Side Chain Deprotonation of Radical Cations”, Angew. Chem. Int. Ed. (2001), 40 (3), 571-573.      IF: 8,255; Cit: 5; DOI: 10.1002/1521-3773(20010202)40:3<571::AID-ANIE571>3.0.CO;2-8
22. PRIVAT, C.; TELO, J.P.; BERNARDES-GENISSON, V.; VIEIRA, A.J.S.C.; SOUCHARD, J.-P.; NEPVEU, F. “Antioxidant Properties of trans-e-Viniferin as Compared to Stilbene Derivatives in Aqueous and Nonaqueous Media”, J. Agr. Food Chem. (2002), 50 (5), 1213        IF: 1,915; Cit: 26; DOI: 10.1021/jf010676t
23. KLEINMAN, M.H.; TELO, J.P.; VIEIRA, A.J.S.C.; BHONE, C.; NETTO-FERREIRA, J.C. "Transient Spectroscopy of Ninhydrin", Photochem. Photobiol. (2003), 77 (1), 10         IF: 1,929; Cit: 4; DOI: 10.1562/0031-8655(2003)0770010TSON2.0.CO2
24. GRAMPP, G.; KELTERER, A-M.; LANGRAF, S.; SACHER, M.; NIETHAMMER, D.; TELO, J.P.; DIAS, R.M.B.; VIEIRA, A.J.S.C. “ESR and ENDOR Investigations on Various Wurster’s Radical Cations in Solution. Experimental Results, Theoretical ab initio, and DFT Calculations”, Monatshefte für Chemie (2005), 136, 519 IF: 0,935; Cit: 6; DOI: 10.1007/s00706-004-0224-4
25. COSTA, D.; VIEIRA, A.J.S.C.; FERNANDES, E. “Dipyrone and Aminopyrine are Effective Scavengers of Reactive Nitrogen Species”, Redox Report (2006), 11(3), 136            IF: 1,593; Cit: 8; DOI: 10.1179/135100006X116637
26. Santos, P.M.P.; Telo, J.P.; Vieira, A.J.S.C. “Structure and Redox Properties of Radicals Derived from One-electron Oxidised Methylxanthines”, Redox Report (2008), 13(3), 123   IF: 2,013; Cit: 1; DOI: 10.1179/135100008X259231
27. JUSTINO, G.C.; Vieira, A.J.S.C. "Antioxidant Mechanisms of Quercetin and Myricetin in the Gas Phase and in Solution - a Comparison and Validation of Semi-Empirical Methods". Journal of Molecular Modeling  (2010), 16(5), 863-876     IF: 2,336 (2009); Cit: 0; DOI: 10.1007/s00894-009-0583-1
28. PINTO, L.F.V.; JUSTINO, G.C.; Vieira, A.J.S.C.; PRABHAKAR, S.; LOBO, A.M. “Thermal Rearrangement of an N-hydroxyimidazole Thiocarbamoyl Derivative as a Simple Entry into the 4-Thioimidazole Motif”, ARKIVOC (2010), v, 17-23   IF: 1,090 (2009); Cit: 0
29. Santos, P.M.P.; Antunes, A.M.M.; Noronha, J.; Fernandes, E.; Vieira, A.J.S.C. “Scavenging activity of aminoantipyrines against hydroxyl radical”, Eur. J. Med. Chem. (2010), 45, 2258-2264 IF: 3,269 (2009); Cit: 0; DOI: 10.1016/j.ejmech.2010.01.071
30. Santos, P.M.P.; SILVA, S.A.G., JUSTINO, G.C.; VIEIRA, A.J.S.C. “Demethylation of Theophylline (1,3-Dimethylxanthine) to 1-Methylxanthine: the First Step of an Antioxidising Cascade”, Redox Report (2010), 15(3), 138 IF: 1,506 (2009); Cit: 0; DOI: 10.1179/174329210X12650506623726
31. MARQUES, M.M.; MARTINS, I.L. CHARNEIRA, C.; VIEIRA, A.J.S.C.; Antunes, A.M.M. “Microwave-based methodology for the preparation of organoselenium compounds”, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,  Volume: 240  (2010)
32. SANTOS, P.M.P.; VIEIRA, A.J.S.C. “Antioxidising activity of cinnamic acid derivatives against oxidative stress induced by oxidising radicals”, J. Phys. Org. Chem. (2013), 26, 432    IF: 1,963; Cit: 0; DOI: 10.1002/poc.3104
33. MARTINS, I.L.; CHARNEIRA, C.; GANDIN, V.; SILVA, J.L.F.; JUSTINO, C.G.;  TELO, J.P.; VIEIRA, A.J.S.C.V.; MARZANO, C.; ANTUNES, A.M.M. “Selenium-Containing Chrysin and Quercetin Derivatives: Attractive Scaffolds for Cancer Therapy”, J. Med. Chem. (2015), 58, 4250 IF: 5,480; Cit: 0; DOI: 10.1021/acs.jmedchem.5b00230
34. VIEIRA, A.J.S.C.; TELO, J.P.; DIAS, R.M.B. "Generation of Hydroxyl Radical by Photolysis of Mercaptopyridine-N-oxides: Application to the Redox Chemistry of Purines", Methods in Enzymology (1999), Vol. 300, Oxidants and Antioxidants, Part B, 194 IF: 4,068; Cit: 3; DOI: 10.1016/S0076-6879(99)00126-3
35. VIEIRA, A.J.S.C. Statement in “Bernardo Jerosch Herold – Testemunhos, Autobiografia” (2010), JM Ed. ISBN: 978-989-8004-11-6
36. VIEIRA, A.J.S.C.; GASPAR, E.M.S.M. “Separation, Purification and Identification of the Components of a Mixture”, Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (2017), The Royal Society of Chemistry, Chap. 1.1, p. 1-5    ISBN: 978-1-84973-963-4
37. MADUREIRA, A.M.; VIEIRA, A.J.S.C.; FERREIRA, M.J.U. “Caffeine Extraction from Tea and Coffee”, Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (2017), The Royal Society of Chemistry, Chap. 1.8, p. 30-34            ISBN: 978-1-84973-963-4
38. VIEIRA, A.J.S.C. “Preparation of Meso-1,2-Dibromo-1,2-diphenylethane”, Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (2017), The Royal Society of Chemistry, Chap. 4.1.1.2, p. 226-228 ISBN: 978-1-84973-963-4
39. VIEIRA, A.J.S.C. “Preparation of Dibenzylideneacetone”, Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (2017), The Royal Society of Chemistry, Chap. 4.2.2.4, p. 342-344 ISBN: 978-1-84973-963-4
40. VIEIRA, A.J.S.C. “Preparation of p-Bromoaniline”, Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (2017), The Royal Society of Chemistry, Chap. 5.1.8, p. 472-476 ISBN: 978-1-84973-963-4
41. VIEIRA, A.J.S.C.; GASPAR, E.M.S.M. “Preparation of Cyclohexene”, Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (2017), The Royal Society of Chemistry, Chap. 9.1.1, p. 600-602 ISBN: 978-1-84973-963-4
42. VIEIRA, A.J.S.C.; SANTOS, P.M.P. “A Tentative Classification of Antioxidants: Which Role They Play when Protecting Biological Targets from Oxidative Stress Induced Damage?”
    J Med Chem Drug Des (2017), 1, 1-3.
43. GASPAR, E.M.; SANTANA, J.C.; SANTOS, P.M.P.; TELO, J.P.; VIEIRA, A.J.S.C. “Gamma irradiation of clove: level of trapped radicals and effects on bioactive composition”,
    J Sci Food Agric (2019), 99, 1668–1674.