Education

Biography

Dr. Kenza E Benzeroual is associate professor and assistant dean for academic and student affairs. Prior joining the college of pharmacy, Dr. Benzeroual was research scientist and National Research Service Award postdoctoral fellow at the College of Physicians and Surgeons of Columbia University in New York, where she was involved in several projects including applied proteomic andgenomic approaches to brain metabolism and disorders. Her current research interests include screening natural products for the neuroprotective and anticancer effects and applying genomic and proteomic approaches in identifying biomarkers for new drug development. Her research has led to several peer-reviewed publications and presentations at national and international meetings. She earned a Ph.D. in pharmacology at the University of Montreal (Canada), received her B.S. in biochemistry/molecular biology, and M.S. in biochemistry/Industrial chemistry from Paul Sabatier University in Toulouse, France, and sherecently completed a M.S. in drug regulatory affairs from Long Island University, Brooklyn, NY.

Research Interest

• Screening for natural products with potential neuroprotective actions in neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease.
• Screening for potential anticancer agents for the treatment of glioblastoma.
• Use of genomic and proteomic approaches in biomarkers identification for new drug development.

Professional Activities:

Teaching Experience:

Professional Activities

• American Society of Pharmacology and Experimental Therapeutics (ASPET)
• American Association of Colleges of Pharmacy (AACP)
• Regulatory Affairs Professional Society (RAPS)
• New York Academy of Sciences (NYAS)
• American Association for the Advancement of Science (AAAS)

Honors & Awards

Publications

1. Radhi Yagnik, and Benzeroual KE. Tigecycline attenuates apoptosis and the release of pro-inflammatory cytokines in lipopolysaccharide-induced PC12 cells. Toxicology In Vitro. (2013) 27: 686-693
2. Tamhane M, Maniar M, Ren C, Benzeroual KE, Taft DR. Disposition Of ON 01210.Na (Ex-RAD®), a Novel Radioprotectant, in the Isolated Perfused Rat Liver: Probing Metabolic Inhibition to Increase Systemic Exposure. J Pharm Sci. (2013) 102(2): 732-40
3. Patel M, Panchal H, Ghribi O, and Benzeroual KE. The Mechanisms underlying the neuroprotective effects of fisetin in the MPTP model of Parkinson’s disease. Journal of Parkinson’s Disease, (2012) 2 (4): 287-302
4. Muchhala SK, and Benzeroual KE. Pentoxifylline suppressed LPS-induced inflammatory and apoptotic signaling in neuronal cells.Advances in Bioscience and Biotechnology. (2012) 3: 731-739
5. Benzeroual KE, Shah B, and Sinde S. Pharmacogenomics: Assessing educational exposure, confidence in knowledge, and training elements of pharmacists. Personalized Medicine. (2012) 9(4): 387-393
6. Dholakiya S, and Benzeroual KE. Protective effect of Diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-a expression.Toxicology In Vitro.(2011) 25(5): 1039-44
7. Yin H, Lin S, Kong SX, Benzeroual KE, Crawford SY, Hedeker D, Lambert BL, Muramatsu N. The Association between Physical Functioning and Self-rated General Health in Later Life: The Implications of Social Comparison. Applied Research in Quality of Life. (2011) 6(1): 1-19
8. Schilit S and Benzeroual K. Silodosin. A new selective alpha1A-adrenergic receptor antagonist for the treatment of benign prostatic hyperplasia. Clinical Therapeutics. (2009) 31 (11): 2489-2502
9. Garland M, Abildskov KM,Taylor S, Benzeroual K, Caspersen C, Arroyo SE, Kiu TW, Reznik B, Weldy P, Daniel SS, and Stark RI. Fetal Morphine metabolism and clearance are constant during late gestation.  Drug Metabolism and Disposition. (2006) 34 (4): 636-646.
10. Haddad PS, Vallerand D, Mathe L, Benzeroual K, and De Werve GV. Synergistic activation of MAPK by insulin and ATP in liver cells: permissive role of calcium. Metabolism. (2003) 52 (5): 590-598.
11. Benzeroual K, Pandey SK, Srivastava AK, Van de Werve G, and Haddad P. Insulin-induced Ca2+ entry into hepatocytes is important for PI3-kinase activation but not for IRb-subunit and IRS-1 tyrosine phosphorylation. B.B.A. (2000) 1495: 14-23
12. Benzeroual K, Van de Werve G, Meloche S, Mathe L, Romanelli A, and Haddad P. Insulin induces calcium influx into isolated rat hepatocyte couplets. Am. J. Physiol. (1997) 272: G1425-G1432.