Sheshadri Narayanan
Sheshadri Narayanan, PhD
Adjunct Clinical Professor of Pathology and Laboratory Medicine

Weill Medical College of Cornell University
USA

Education

 1971

Ph.D

Biochemistry

Graduate School of Basic Medical Sciences New York Medical College, New York City

 

Biography

 

Research Interest

  • Preanalytical issues in all areas of Laboratory Medicine (Clinical Chemistry, Hematology, Coagulation, Microbiology and Molecular techniques; topics covered in 2 of my books).
  • Interaction of Herbs with drug assays thus impacting therapy (covered in one of my books).
  • Principles and techniques in Laboratory Instrumentation (covered in one of my books).
  • In addition I'm interested in enzymology, laboratory methods such as creatinine (publications on both topics) and application of clinical laboratory statistics. As an educator my interests cover a wide gamut of topics in Laboratory medicine.

 

Professional Activities:

2001-Present Adjunct Clinical Professor Pathology and Laboratory Medicine Weill Medical College of Cornell University.
1983-                                   Clinical Professor Department of Pathology New York Medical College, Valhalla, New York
1986-2000 Adjunct Clinical Associate Professor Department of Pathology New York University Medical Center, New York, NY
Current Hospital Appointment
10/1/14-present Director Clinical Laboratory New York-Presbyterian Hospital, Westchester

 

Publications

  1. Narayanan, S. and Appleton, H.D., "Specificity of Accepted Procedures for Urine Creatinine". Clin. Chem. 16, 536, 1970
  2. Narayanan, S. and Appleton, H.D., "Specificity of Accepted Procedures for Urine Creatinine". Clin. Chem. 18, 270, 1972
  3. Narayanan, S. and Appleton, H.D., "A New Rapid Procedure for Purifying Phosphomonoesterase (E.C.3.1.3.1.) from Human Intestinal Mucosa". Clin. Chem. 17, 667, 1971
  4. Narayanan, S. and Appleton, H.D., "New Procedure for Purifying and Crystallizing Alkaline Phosphatase from Human Intestinal Mucosa". Clin. Chem. 18, 548, 1972
  5. Narayanan, S. and Appleton, H.D., "Specificity Studies on Human Intestinal Alkaline Phosphatase", Biochemica et Biophysica Acta (Netherlands) 284, 175, 1972.
  6. Narayanan, S. and Appleton, H.D., "Studies on Human Intestinal Alkaline Phosphatase", Scand. J. Clin. Lab. Invest., 29 Suppl. 126, 23 - 36, 1972
  7. Narayanan, S. and Appleton, H.D. "Evaluation of Simplified Procedures for Purification of Human Intestinal Alkaline Phosphatase". Clin. Chem. 18, 702, 1972
  8. Narayanan, S. and Appleton, H. D., "Evaluation of Phosphorylethanolamine and Phosphorylcholine as Substrates for Human Intestinal Alkaline Phosphatase". Clin. Chem. 19, 664, 1973
  9. Narayanan, S., "Studies on Serum Alkaline Phosphatase from Patients with Liver Disease".  Clin. Chem. 20, 896, 1974
  10. Narayanan, S., "The Influence of Blood Collection Medium on Trace Metal Analysis".  Clin. Chem. 20, 902, 1974
  11. Leon, L.P., Narayanan, S., Dellenbach, R., and Horvath, C., "Immobilized Glucose Oxidase for the Determination of Serum Glucose on Technicon's Auto Analyzer".  Clin. Chem. 20, 872, 1974
  12. Leon, L.P., Narayanan, S., Dellenback, R., and Horvath, C., "Immobilized Glucose Oxidase Used in the Continuous Flow Determination of Serum Glucose". Clin. Chem. 22, 1017, 1976
  13. Peckauskas, R.A., Portnoy, A.L., and Narayanan, S., "Investigations into the Biochemical Changes in the Red Cell Membrane Following Irradiation of Plasma". Clin. Chem. 21, 998, 1975
  14. Kashani, M., Parl, F., Narayanan, S., Pavlovec, R., and Green, R., "Rapid Determination of Albuminuria and Globulinuria in Urine, Based upon pH Measurements at 25°C and 37°C, "Ann. Clin. Lab. Sci., 6, 356, 1976
  15. Narayanan, S., "Purification of Alkaline Phosphatase" a chapter in "Alkaline Phosphatase" by G. N. Bowers, R. McComb and S. Posen, Plenum Publishing Company, New York, 1979
  16. Narayanan, S., "Performance Characteristics of Serum Separation Devices Utilizing Clinical Chemistry Procedures", Proc. 2nd European Congress on Clinical Chemistry, Prague, Czechoslovakia, 1976
  17. Narayanan, S., and Kashani, M., "Relative Merits of Kinetic and End Point Analysis", Manual of Laboratory Procedures for Clinical Enzymology, Association of Clinical Scientists, Institute for Clinical Science, Publishers. 1976
  18. Narayanan, S., "Standardization and Measurements of Nicotine - Adenine -Dinucleotides", Proc. Seminar on Clinical Enzymology, Association of Clinical Scientists, Institute for Clinical Science, Publishers.  1976
  19. Narayanan, S., "An Evaluation of Methods for Monitoring Enzyme Activity", check sample, American Society of Clinical Pathologists, Chicago, Illinois, Publishers.  1977
  20. Yae, Y., Narayanan, S., and Okochi, K., "Studies on Serum Alkaline Phosphatase Associated with Lipoprotein X in Patients with Obstructive Jaundice".  Clin. Chem. 23, 1156, 1977
  21. Peckauskas, R.A., Peckauskas, J., Portnoy, A.L., and Narayanan, S.  "Studies on the Invitro Effects of a Tumor Cell Radiosensitizing Drug on Serum Enzyme Activities".  Clin. Chem. 24, 1036, 1978
  22. Narayanan, S. Laessig, R.H., Westgaard, J.O., Habig, R.L., and Butts, W.C., "Evaluation of an Improved Serum Separator Tube for Clinical Chemistry Determinations".  Clin. Chem. 24, 1019, 1978 .
  23. Moore, J.J., Sax, S.M., and Narayanan, S., "Efficacy of Iodoacetate as a Glycolytic Inhibitor and its Utility in Clinical Chemistry Procedures", Clin. Chem. 24, 998, 1978 .
  24. Lin, F.C., Fay, A., Iannuzzelli, V.F., and Narayanan, S., "Evaluation of an Improved VACUTAINER Tube for Trace Metals and Routine Clinical Chemistry Determinations", Clin. Chem. 24, 1019, 1978 .
  25. Narayanan, S., "Lipoprotein-X", Crit. Rev. in Clin. Lab. Sciences. Vol. 11, Issue 1, 31-51, 1979.
  26. Ince, G, Fay, A, Lin, F.C, Narayanan, S, Cushman, F.R, & Portnoy, A.L, "Considerations in the Assays for Serum Creatinine", Clin. Chem., 25, 1092, 1979 .
  27. Sax, S.M., Moore, J.J., Narayanan, S., and Levy, A.L., "Comparison of Total and Isoenzyme Activities of Lactate Dehydrogenase (LD) and Creatine Kinase (CK) in Serum Obtained from Blood With and Without Contact with Polymeric Separating Material", Clin. Chem., 25, 1099, 1979
  28. Narayanan, S., Hassemer, D.J., Laessig, R.H., Habig, R.L., Butts, W.C., and Borkowski, J.D., "Control of Blood Collection and Processing Variables to Obtain Extended (greater than five days) Stability in Serum Constituents", Clin. Chem., 25, 1086, 1979 .
  29. Lin, F.C., Fay, A., Narayanan, S., Menendez-Botet, C., and Schwartz, M.K., "Comparative Data on Serum Trace-Metal Levels using a New Evacuated Blood-Collection Tube", Clin. Chem. 25, 1148, 1979 .
  30. Kiyasu, J.Y., Levy, A.L., and Narayanan, S., "A Comparison of Serum Amylase Methodologies", Clin. Chem. 25, 1148, 1979 .
  31. Echemendia, E., Narayanan, S., Van Heertum, R.L., and Guzman, L., "Validation of an Integral Serum Separator for Selected Radioimmunoassay Procedures", Clin. Chem. 25, 1154, 1979 .
  32. Narayanan, S., and Kiyasu, J.Y., "Performance Characteristics of Newly Designed Columns for the Quantitative Analysis of CK-MB", Clin. Chem. 26, 978, 1980 .
  33. Stiller, R.C., Perel, J.M., Lin, F.C., and Narayanan, S., "A Comparative Study of  Serum versus Plasma for Tricycli Antidepressant Drugs", Clin. Chem. 26, 1000, 1980 .
  34. Kessler, K.M., Keival, J., and Narayanan, S., "Effect of Blood-Collection System on Percent (%) of Free Quinidine Measured in Serum", Clin. Chem. 26, 1004, 1980 .
  35. Lin, F.C., Narayanan, S., Stiller, R.C., and Perel, J.M., "Efficacy of Evacuated Tubes With and Without Anticoagulant for the Gas Chromatographic Determination of Lidocaine, Primidone and Theophylline", Clin. Chem. 26, 1005, 1980 .
  36. Yae, Y., Narayanan, S., Nagamine, M., and Okochi, K., "Investigations on Sera Containing Two Electrophoretic Bands of Alkaline Phosphatase Activity", Clin. Chem. 26, 1019, 1980 .
  37. Ono, T., Kitaguchi, K., Takehara, M., Shiiba, M., and Narayanan S., "Effect of Time and Temperature of Storage of Clotted Blood on Serum Constituents", Clin. Chem. 26, 1980 .
  38. Ince, G., Fay, A., Lin, F.C., Narayanan, S., Portnoy, A.L., and Harrigan, T., "Evaluation of Thrombin-Containing Blood Collection Tubes for Stat. Procedures", Clin. Chem. 26, 1060, 1980 .
  39. Portnoy, A.L., Harrigan T., Ince, G., Fay, A., Lin, F.C., and Narayanan, S., "A comparative Study of Creatinine Assays".  Clin. Chem. 26, 1062, 1980 .
  40. Pasciolla, P., Ince, G., Fay, A., Lin, F.C., Narayanan, S., and Portnoy, A.L., "An Evaluation of Selected Enzyme Immunoassay Procedures Using Serum and Plasma", Clin. Chem. 26, 1070, 1980 .
  41. Narayanan, S., and Appleton, H.D., "Creatinine" A Review". Clin. Chem. 26, 1119, 1980.
  42. Narayanan, S., "Evaluation of Selected Immunoanalytical Techniques", check sample, American Society of Clinical Pathologists, Chicago, Illinois, Publishers 1980.
  43. Narayanan, S., "Standardization of Creatinine Assays".  In Manual of Procedures for the Applied Seminar on Laboratory Diagnosis and Monitoring of Disorders of the Kidney.  Institute of Clinical Science, Inc., Philadelphia, Publishers, 1980, p. 63.
  44. Kasay, S., Walder, H., Lin, F.C., & Narayanan, S., "Evaluation of a Trace Metal Blood Collection Tube with EDTA as Anticoagulant", Clin. Chem. 27, 1030, 1981 .
  45. Ennis, B., Ince, G., Fay, A., Pathak, R., Lin, F., Narayanan, S., Portnoy, A.L., and Harrigan,T., "A Comparative Evaluation of Kinetic and High Performance Liquid Chromatographic Assays for Serum Creatinine". Clin. Chem. 27, 1034, 1981 .
  46. Portnoy, A.L., Harrigan, T., Likeas, P., and Narayanan, S., "Evaluation of Effect of Hemoglobin on the Determination of Bilirubin", Clin. Chem. 27, 1037, 1981 .
  47. Echemendia, E., Van Heertum, R.L., Guzman, L., and Narayanan, S., "A Comparative Study of Triiodothyronine (T3) Radio Assays Kits and Effects of Specimen Collection", Clin. Chem 1072, 1981 .
  48. Pathak, R., Lin, F.C., Narayanan, S., and Levy, A.L.,  "Evaluation of Specimen Collection for the Analysis of Theophylline", Clin. Chem. 27, 1086, 1981 .
  49. Lin, F.C., Pradhan, S., Narayanan, S., Stiller, R.C., and Perel, J.M., "An Evaluation of a Gas Chromatographic Procedure for Tricyclic Antidepressants", Clin. Chem., 27, 1102, 1981 .
  50. Levy, S., Kaufman, G., Dioso, C., Sternschein, P., Lin, F.C., DePolo, G., and Narayanan, S.,  "Whole Blood to Plasma Distribution Ratio of Tricyclic Antidepressants", Clin. Chem. 27, 1102, 1981 .
  51. Perel, J.M., Stiller, R.C., Lin, F.C., & Narayanan, S., "Effect of Specimen Collection on the Analysis of Haloperidol, a Neuroleptic Drug", Clin. Chem. 27, 1102, 1981 .
  52. Narayanan, S. "Spectrophotometry: Fundamental Concepts", J.Clin.Lab.Autom 1. 13, 1981
  53. Echemendia, E., Van Heertum, R.L., Guzman, L. and Narayanan, S., "Considerations in the Assay of Triiodothyronine (T3) by Radioimmunoassay", J. Clin. Chem. Clin. Biochem. 19, 657, 1981 .
  54. Sarkozi, L., Ramanathan, L. and Narayanan, S., "In Vitro and Methodological Effects of Sodium, Ammonium and Lithium Heparinate on Frequently Assayed Biochemical Constituents", J. Clin. Chem. Clin. Biochem. 19, 825, 1981 .
  55. Narayanan, S., "Spectrophotometry:  II Components and Quality Control", J. Clin. Lab. Autom. 1, 89, 1981.
  56. Narayanan, S., Fluorometry", J. Clin. Lab. Autom. 2, 14, 1982.
  57. Narayanan, S., "Flame Photometry", J. Clin. Lab. Autom., 2, 87, 1982.
  58. Kessler, K.M., Ho-Tung, P., Steele, B., Silver, J., Pickoff, A., Narayanan, S. and Myerburg, R.J., "Simultaneous Quantitation of Quinidine, Procainamide, and N-Acetylprocainamide in Serum by Gas-liquid Chromatography With a Nitrogen phosphorus Selective Detector.  Clin. Chem. 28, 1187, 1982.
  59. Narayanan, S., "Biochemistry and Clinical Significance of Lipoprotein-X in Clinical Biochemistry, Contemporary Theories and Techniques", Vol. 2. Spiegel, H.E., Editor, Academic Press, New York 1982.  Pages 1-12.
  60. Narayanan,S.,"Method-Comparison Studies on Immunoglobulins",Clin. Chem. 28, 1528 1982.
  61. Schlindwein, P., Ince, G., Lin, F.C., Narayanan, S. and Levy, S., "Comparison of Blood Collection  Systems for the Determination of Plasma Plasminogen and Prekallikrein Using Chromogenic Substrates", Clin. Chem. 28, 1585, 1982
  62. Chiara, J.C., Ince, G., Lin, F.C., and Narayanan, S., "Effect of Zinc Ions on Coagulation Assays", Clin. Chem. 28, 1586, 1982 .
  63. Kasay, S., Schlindwein, P., Ince, G., Lin, F.C., Narayanan, S. and Portnoy, A.L., "A Comparative Study of Quantitative Methods for Determination of Heparin",  Clin. Chem. 28, 1587, 1982 .
  64. Pradhan, S., Ennis, B., Ince, G., Lin, F.C., Narayanan, S., Stiller, R.L. and Perel, J.M., "Effects of Methodology and Blood Collection System for the Determination of Blood Alcohol",  Clin. Chem. 28, 1587, 1982 .
  65. Levy, S., Johnson, J., DePolo, G., Lin, F.C. and Narayanan, S.,  "Whole Blood to Plasma Distribution Ratio of Haloperidol, a Neuroleptic Drug", Clin. Chem. 28, 1588 1982 .
  66. Wong, S.H., Jain, N., Jain, P., Santiago, C., Lin. F.C., and Narayanan, S., "Effect of Anticoagulants in Blood Collection System on the Analysis of Tricyclic Antidepressants (TCA) by High Performance Liquid Chromatography", Clin. Chem. 28, 1644 1982 .
  67. Kiyasu, J., Napoles, D., Gonzales, M.A., Hauschild, U., Ince, G., Lin, F.C. and Narayanan, S., "Stat and Routine Chemistry Analyses Utilizing Thrombin Containing Blood Collection Tubes", Clin. Chem. 28, 1656, 1982
  68. Likeas, F., Harrigan, T., Portnoy, A.L., and Narayanan, S., "An Improved Solvent System and Spray for TLC Determination of Phospholipids in Amniotic Fluid", Clin. Chem. 28, 166o, 1982 .
  69. Narayanan, S., "Atomic Absorption Spectroscopy", J. Clin, Lab. Autom. 2, 243, 1982.
  70. Narayanan, S., Lin, F.C., and Ince, G., "Clinical Chemistry Analytes:  A Comparison of Specimen Collection Methods", proceedings 2nd Asian-Pacific Congress of Clinical Chemistry, Abstract #157, Page 168, 1982.
  71. Narayanan, S., "Electroanalytical Methods:  1. pH Measurements by Potentiometry", J.Clin.Lab.Autom. 2, 393, 1982.
  72. Narayanan, S., "Electroanalytical Methods II. Coulometry, Polarography, and Anodic Stripping Voltammetry", J. Clin. Labs. Autom. 3, 9, 1983.
  73. Narayanan, S., "Chromatography: I. Theoretical Aspects", J. Clin. Lab. Autom. 3, 88, 1983.
  74. Narayanan, S., "Alkaline Phosphatase As Tumor Marker". Ann. Clin. Lab. Sci. 13, 133, 1983.
  75. Narayanan, S., and Lin, F.C., "Sampling Considerations in Trace Metal Analysis."  Proceedings of International Symposium on Health Effects and Interactions of Essential and Toxic Elements, Lund, Sweden, 1983. P.32
  76. Levy, S.A., Dioso, C., Ince, G., and Narayanan, S., "Stability Studies on Immuno-globulins and Selected Specific Proteins Using Rate Nephelometry." Proceedings of 5th European Congress of Clinical Chemistry, Budapest, Hungary, 1983. P. 333
  77. Lin, F.C., Kasay, S., and Narayanan, S., "Evaluation of Blood Specimen Collection Containers for Trace Metal Analysis."  Proceedings of 2nd International Conference on the Clinical Chemistry and Chemical Toxicology of Metals, Montreal, Canada, 1983. P. 69
  78. Perel, J.M., Stiller, R.L., Lin, F.C. and Narayanan, S.  "A Comparative Study of Serum versus Plasma for Mexiletine, an Antiarrhythmic Drug", Clin. Chem. 29, 1166, 1983.  .
  79. Stiller, R.L., Perel, J.M., Lin, F.C. and Narayanan, S., "Effect of Specimen Collection and Preparation on the Radioimmunoassay (RIA) of Thioridazine", Clin. Chem. 29, 1210, 1983  
  80. Wong, S.H., White, W.B., Holden, R., Narayanan, S. and Lin, F.C., "Effect of Blood Collection Systems on the Analysis of Propranolol", Clin. Chem. 29, 1236, 1983.
  81. Stiller, R.L., Perel, J.M., Lebowitz, S., Maitz, G., Lin, F.C., and Narayanan, S., "Comparison of EDTA - Derived Plasma and Serum from Serum Separator Tubes in the Assay of Selected Basic Drugs", Clin. Chem. 29, 1236, 1983 .
  82. Shaw, L.M., Fields, L., Schlindwein, P., Ince, G., Lin, F.C. and Narayanan, S. "A Study of the Influence of Several Variables on the Protein Binding of Quinidine", Clin. Chem. 29, 1240, 1983.  .
  83. Echemendia, E., Van Heertum, R.L., Guzman, L. and Narayanan, S., "Evaluation of Various Blood Collection Tubes for the Determination of Free T4 by RIA", Clin. Chem. 29, 1184, 1983. 
  84. Hammond, K.B., Hare, L.A., Schlindwein, P., Wiseman, J., Ince, G. and Narayanan, S., "Evaluation of a Plasma Separator Micro-blood Collection Device Containing Lithium Heparin as Anticoagulant", Clin. Chem. 29, 1220, 1983 
  85. Pearson, K.H., Schermaier, A.J., Tyko, S.A., Kasay, S., Lin, F.C. and Narayanan, S., "Evaluation of Trace Metal VACUTAINER Tubes by Zeeman AAS", Clin. Chem. 29, 1286, 1983. 
  86. Narayanan, S., "Chromatography: II.  Paper and Thin Layer Techniques", J. Clin. Lab. Autom. 3, 148, 1983.
  87. Narayanan, S., "Chromatography: III. Ion-exchange Chromatography", J. Clin. Lab. Autom. 3, 225, 1983.
  88. Yae, Y., Ishii, N., Mori, T., Okochi, K. and Narayanan, S.,"Semiautomated Determination of Urinary 17-hydroxycorticosteroids as Porter-Silber Chromogens". Clin.Chem. 29 1695-1697, 1983.
  89. Narayanan, S., "Chromatography: IV. Gel Permeation Chromatography", J. Clin. Lab. Autom. 3, 369, 1983.
  90. Narayanan, S., "Methodology and Stability of Selected Analytes used as Markers of Myocardial Disease", Upsala, J. Med. Sci. 88:201, 1983.
  91. Narayanan, S., "Chromatography: V. Affinity Chromatography", J. Clin. Lab. Autom. 4:82, 1984.
  92. Narayanan, S., Ince, G., and Chiara. J., "Effect of Iodoacetate Concentration on Ability to Inhibit Glycolysis," Revista Brasileira De Analises Clinicas, 16 89, 1984 .
  93. Narayanan, S., Kasay, S., Lin, F.C., Pearson, K.H., Schermaier, A.J. and Tytko, S.A., "Contamination Studies of Trace Metal VACUTAINER Brand Tubes by the Zeeman 5000 AAS System," Revista Brasileira De Analises Clincas, 16 131, 1984 .
  94. Stiller, R.L., Perel, J.M., Feldman, B., Lin, F.C. and Narayanan, S., "Comparison of Serum and Plasma Samples for the Analysis of a Model Basic Drug: Desmethylimipramine (DMI).  Clin.Chem. 30, 1028, 1984
  95. Stiller, R.L., Perel, J.M., Sallee, F.R., Moles, L., Lin, F.C. and Narayanan, S., "Application of New High Performance Liquid Chromatographic (HPLC) Method for Pemoline in Children Using Capillary and Venous Blood Samples". Clin.Chem. 30, 1031, 1984 .
  96. Wong, S.H., Pena, Y., Lin, F.C., and Narayanan, S.  "Suitability of Blood Collection Systems for Antiepileptics Analysis by Fluorescence Polarization Immunoassay (FPIA)".  Clin. Chem. 30, 1032, 1984 .
  97. Echemendia, E., Van Heertum, R.L., Guzman, L., Narayanan, S., Ince, G.  "The Stabilizing Effect of Aprotinin on Selected Hormone Assays".  Clin. Chem. 30, 1051, 1984 .
  98. Narayanan, S., "Chromatography:VI-Gas Chromatography," J. Clin. Lab. Autom. 4, 302, 1984.
  99. Narayanan, S., "Biochemistry and Clinical Relevance of Lipoprotein-x", Ann. Clin. Lab. Sci. 14, 371, 1984.
  100. Narayanan, S., and Lin, F.C., "Sampling Technique" in "Therapeutic Drug Monitoring", Wong, S.  Editor, Marcel-Dekker, New York 1984, PP. 79-88.
  101. Narayanan, S., "Chromatography: VII-High Performance Liquid Chromatography," J. Clin. Lab. Autom. 4, 377, 1984.
  102. Narayanan, S., and Lin, F.C., Sampling Considerations in Trace Metal Analysis, Nutrition Research, Supp. I, 59, 1985.
  103. Sarkozi, L., Narayanan, S., Ramanathan, L.V. and Klion, E.M., In vitro effect of ammonium, lithium and sodium heparin on laboratory tests. Biochimica Clinica, 8, 2071-2074, 1984.
  104. Narayanan, S., "Considerations in therapeutic drug monitoring." Italian. J. Clin. Pathol. 1, 73, 1984
  105. Narayanan, S., "Laboratory Evaluation of the Adrenogenital Syndrome", Ann. Clin.Lab.Sci. 15, 159, 1985.
  106. Wong, S.H., White, W.B., Marzouk, N., Lin, F.C., and Narayanan, S., "Suitability of Blood Collection Systems for the Analysis of Atenolol by HPLC," Clin.Chem. 31, 926, 1985 .
  107. Stiller, R.L., Perel, J.M., Curran, S., Lin, F.C., and Narayanan, S., "Therapeutic Drug Monitoring (TDM) of Haloperidol in the presence of its reduced metabolite," Clin.Chem. 31, 939, 1985 .
  108. Perel, J.M., Stiller, R.L., Feldman, B.L., Lin, F.C., and Narayanan, S., "Therapeutic Drug Monitoring (TDM) of the Amitryptyline (AT)/perphenazine (PER) interaction in depressed patients," Clin.Chem. 31 939, 1985 .
  109. Narayanan, S., Methodologic approaches to creatinine analysis check sample (cc-162), 4-1985.  American Society of Clinical Pathologists. Chicago, Illinois, 1985
  110. Wong, S.H., DePolo, G., Lin, F.C., and Narayanan, S., "Stability assessment of desipramine (DMI) and Imipramine (IMI) in specimens collected in evacuated blood collection tubes," Clin.Chem. 31, 940, 1985 .
  111. Perel, J.M., Stiller, R.L., Sallee, F.R., Lin, F.C., and Narayanan, S., "Comparison between microsampling and venipuncture techniques for therapeutic drug monitoring (TDM) of tricyclic antidepressants (TCA)," Clin.Chem. 31, 940, 1985 .
  112. Walder, H., Lin, F.C., and Narayanan, S., "Evaluation of improved trace metal blood collection tubes by Zeeman Atomic Absorption Spectrophotometer (AAS)", Clin.Chem. 31, 992, 1985 .
  113. Chiara, J., Ince, G., and Narayanan, S., "Effect of lithium iodoacetate on routine clinical chemistry analytes," Clin.Chem. 31, 1022, 1985 .
  114. Wong, S.H.Y., White, W.B., Fernandes, R., Holden, R., Lin, F.C., Narayanan, S., "Assessment of Blood Collection Systems for the high performance liquid chromatographic measurement of propranolol," Ther.Drug Monit. 7, 358,1985.
  115. Narayanan, S., Kasay, S., Lin, F.C., Pearson, K.H., Shermaier, A.J. and Tytko, S.A. "Assessment of Levels of Contamination from Evacuated Blood Collection Tubes" in "Trace Elements in Man and Animals," Commonwealth Agricultural Bureau, Slough, United Kingdom, Mills, C.F., Brenner, L., and Chesters, J.K., Editors, Pages 657-659, 1985.
  116. Foglia, J.P., Perel, J.M., Stiller, R.L., Lin, F.C., and Narayanan, S., "Effect of Specimen Collection on Immunoassay Techniques for Selected Tricyclic Antidepressant Drugs."  Clin.Chem. 32, 1052, 1986.
  117. Stiller, R.L., Perel, J.M., Davis, P., Chakravorti, S., Lin, F.C., and Narayanan, S., "Comparative Evaluation of Anticoagulants Used in Blood Collection System for Assay of Histamine."  Clin.Chem. 32, 1056, 1986.
  118. Perel, J.M., Stiller, R.L., Chakravorti, S., Lin, F.C., and Narayanan, S., "Evaluation of Blood Collection Systems for the Assay of Biogenic Amines." Clin.Chem. 32, 1058, 1986.
  119. Perel, J.M., Stiller, R.L., Pollock, R.G., Lin, F.C., and Narayanan, S., "Pharmacokinetic Studies on Oral and Intravenous Chlomipramine."  Clin.Chem. 32, 1059, 1986.
  120. Stiller, R.L., Perel, J.M., Sallee, F.R., Lin, F.C., and Narayanan, S., "Pharmacokinetic Studies of Pemozide Using Capillary Blood Microcollection System." Clin.Chem. 32, 1061, 1986.
  121. Narayanan, S. "Relative merits of plasma derived from three heparin salts and serum for sodium and potassium measurements by direct and indirect potentiometry", proceedings of the 4th meeting of the European Working Group on ion selective electrodes, Helsinki, 1985 in methodology and clinical applications of ion selective electrodes, Volume 7, 209, 1986, published by International Federation of Clinical Chemistry, Copenhagen, Denmark.
  122. Narayanan, S., Lin, F., and Walder, H., Sampling considerations in trace element analysis, Acta.Pharmacol. Toxicol. 59, 598, 1986
  123. Narayanan, S., "Analytical Aspects Of Tests For Renal Disease."  Italian J. of Clin. Pathol. - 1 #2, 7, 1986.
  124. Narayanan, S. "Effect of concentration of heparin salts used as anticoagulants for ion selective electrode (ISE) measurements of sodium and potassium.", Proceedings of the 8th meeting of the European Working Group on Ion Selective Electrodes, Vol 8,199,1987 published by the International Federation of Clinical Chemistry, Copenhagen, Denmark.
  125. Wong, S.H.Y., Pena, Y., Lin, F.C. and Narayanan, S., "Assessment of evacuated serum separator gel blood collection tubes for antipileptic monitoring by FPIA." Clin.Chem. 33, 1017, 1987 .
  126. Foglia, J.P., Stiller, R.L., Perel, J.M., Lin, F.C. and Narayanan, S., "The measurement of plasma nortriptyline (NT) and its isomeric 10-hydroxy metabolites." Clin.Chem. 33, 1014, 1987 .
  127. Stiller, R.L., Perel, J.M., Birder, L., Foglia, J.P., Lin, F.C. and Narayanan, S. "The measurement of plasma imipramine (IMI) and their respective 2-hydroxy metabolites." Clin.Chem. 33, 1025, 1987 .
  128. Perel, J.M., Foglia, J.P., Birder, L., Lin, F.C. and Narayanan, S.  "The use of therapeutic drug monitoring of imipramine (IMI) desipramine (DMI) in the maintenance therapy of patients." Clin.Chem. 33, 1025, 1987 .
  129. Narayanan, S., "Protection of peptidic substrates by protease inhibitors." Biochemica Clinica 11, 954, 1987.
  130. Perel, J.M., Foglia, J.P., Marisakalian, M., Lin, F.C., and Narayanan, S., "Monitoring of imipramine and desipramine in patients with panic and phobic disorders."  Clin. Chem. 34, 1262, 1988 .
  131. Perel, J.M., Birder, L.A., Kahn, E.M., Lin, F.C., and Narayanan, S., "Plasma levels of haloperidol and its reduced metabolite during combination therapy with carbamazepine or lithium of schizophrenic patients."  Clin. Chem. 34, 1266, 1988 .
  132. Perel, J.M., Russell, A.D., Foglia, J., Lin, F.C., and Narayanan, S., "Predictive monitoring of nortryptyline with geriatric depressed patients." Clin. Chem. 34, 1266, 1988 . 
  133. Stiller, R.L., Perel, J.M., Pollack, B.G., Birder, L., Lin, F.C., and Naryanan, S., "Application of electrochemical detection high performance liquid chromatography for intravenous clomipramine in adults."  Clin. Chem. 34, 1272, 1988 .
  134. Lin, F.C., Walder, H., and Narayanan, S., "Evaluation of improved trace metal blood collection tubes by Zeeman Atomic Absorption Spectroscopy."  Clin. Chem. 34, 1306, 1988 .
  135. Narayanan, S., "Aspects of trace element analysis." Biochemica Clinica 12, 552, 1988.
  136. Narayanan, S., "Creatinine:  Review of methods."  Check Sample Pts 88-78 (PTS-33).  American Society of Clinical Pathologists, Chicago, Illinois  Publishers 1988.
  137. Narayanan, S., "Approaches to Minimization of preanalytical error." Italian J. of Clin, pathol. 3, suppl. 5, 13, 1988.
  138. Narayanan, S., and Fink, J.G., "Interpretation of serum protein electrophoretic patterns:  A practical approach." proceedings of the Fourth Asian-Pacific Congress of Clinical Biochemistry, Hong Knog, 1988. pages 477-485.
  139. Perel, J.M., Foglia, J.P., Curran, S., Lin, F.C., and Narayanan, S., "Indirect therapeutic drug monitoring (TDM) by measurement of monoamine oxidase (MAO) activities from platelets." Clin. Chem., 35, 1175 1989
  140. Perel, J.M., Stiller, R.L., Curran, S., Lin, F.C., and Narayanan, S., "Low dose monitoring of haloperidol."  Clin. Chem. 35, 1179, 1989
  141. Foglia, J.P., Perel, J.M., Lin, F.C. and Narayanan, S., "A new method for the monitoring of fluvoxamine in human plasma by HPLC with U.V. detection." Clin. Chem.  35, 1185, 1989
  142. Narayanan, S., "Inhibition of invitro platelet aggregation and release and fibrinolysis" Ann., Clin. Lab. Sci. 19, 260, 1989.
  143. Narayanan, S., "Preanalytical considerations in coagulation assays.  In 'sampling' proceedings of preanalytical phase of coagulation" Tokyo Medical College, 1989, pages 46-59.
  144. Narayanan, S. "Current Status of DNA Probe Utilization in the Clinical Laboratory:  A discussion of cost effectiveness and Outlook for the Future", Bull. Mol. Biol. Med 14:157, 1989.
  145. Foglia, J.P., Perel, J.M., Nathan, R.S., Pollock, B.G., Lin, F.C. and Narayanan, S., "Therapeutic Drug Monitoring (TDM) of FluoVaxamine, a selective antidepressant." Clin. Chem. 36, 1043, 1990 .
  146. Perel, J.M., Pollock, B.G., Rudolph, G., Lin, F.C., and Narayanan, S., "Effects of Varying dosages and routes of administration on the plasma levels of clomipramine (CMI)." Clin. Chem. 36, 1044, 1990 .
  147. Narayanan, S., "Preanalytical considerations in coagulation analysis", Bioquimica 15, 33, 1990.
  148. Narayanan, S., "Serum alkaline Phosphatase isoenzymes as markers of liver disease", Ann. Clin. Lab. Sci. 21, 12, 1991
  149. Narayanan, S., "Creatinine:  Review of Methods", check sample pts 91-1 (pts - 51).  American Society of Clinical Pathologists, Chicago, Illinois Publishers 1991.
  150. Lin, F.C., Pradhan, S., Narayanan, S., Perel, J.M., Sorisio, D., and Foglia, J. P., "Comparison of serum from red-top and experimental serum separator gel tubes in the assay of tricyclic antidepressants." Clin. Chem. 37, 994, 1991

 

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