Publications

  1. Ende N, Rameshwar P, Ende M. Fetal cord blood's potential for bone marrow transplantation. Life Sci. 44:1987-90, 1989.
  2. Rameshwar P, Gascón P, Ganea D. Immunoregulatory effects of neuropeptides stimulation of IL-2 production by substance P. J. Neuroimmunol. 37:65-74, 1992.
  3. Lin TZ, Svetic A, Ganea D, Rameshwar P, Gascón P, Gause W, Raveche E. Cytokines in NZB CD5+ B clones. Ann. N.Y. Acad. Sci. 651:581, 1992.
  4. Gascón P, Sathe S, Rameshwar P. Impaired erythropoiesis in the acquired immunodeficiency syndrome with disseminated Mycobacterium Avium complex. Am. J. Med. 94:41-48, 1993.
  5. Rameshwar P, Gascón P. Release of IL-1 and IL-6 from human monocytes by antithymocyte globulin. Requirement for de novo synthesis. Blood 80:2531-8, 1992.
  6. Rameshwar P, Ganea D, Gascón P. In vitro stimulatory effect of substance P on hematopoiesis. Blood 81:391-8, 1993.    
  7. Rameshwar P, Gascón P, Ganea D. Stimulation of interleukin 2 production in murine lymphocytes by substance P and related tachykinins. J. Immunol. 151:2484-96, 1993.
  8. Rameshwar P, Ganea D, Gascón P. Induction of IL-3 and GM-CSF by substance P in bone marrow cells is partially mediated through the release of IL-1 and IL-6. J. Immunol. 152:4044-54, 1994.
  9. Rameshwar P, Denny T, Stein D, Gascón P. Adhesion of monocytes from patients with bone marrow fibrosis is required for the production of fibrogenic cytokines. Potential role for IL-1 and TGF-ß. J. Immunol. 153:2819-30, 1994.
  10. Rameshwar P, Gascón P. Substance P (SP) mediates production of stem cell factor and interleukin-1 in bone marrow stroma: Potential autoregulatory role for these cytokines in SP receptor expression and induction Blood 86:482-90, 1995.
  11. Raff GW, Livingston DH, Wang MT, Rameshwar P. Hemorrhagic shock abolishes the myelopoietic response to turpentine induced soft tissue injury. J. Surg. Res. 59:75-79, 1995.
  12. Rameshwar P, Chang VT, Gascón P. Implication of CD44 in adhesion-mediated overproduction of TGF-ß and IL-1 in monocytes from patients with bone marrow fibrosis. Br. J. Haematol. 93:22-29, 1996.
  13. Rameshwar P, Gascón P. Induction of negative hematopoietic regulators by neurokinin-A in bone marrow stroma. Blood 88:98-106, 1996.
  14. Rameshwar P, Denny TN, Gascón P. (1996) Enhanced HIV-1 activity in bone marrow can lead to myelopoietic suppression partially contributed by gag p24. J. Immunol. 157:4244-50.
  15. Rameshwar P, Poddar A, Zhu G, Gascón P. Receptor induction regulates the synergistic effects of substance P with IL-1 and PDGF on the proliferation of bone marrow fibroblasts. J. Immunol. 158:3417-24, 1997.
  16. Mohr AM, Upperman JS, Taneja R, Wang MT, Rameshwar P, Livingston DH. The differential effects of acute hypoxia and endotoxin on the secretion and expression of bone marrow interleukin-1 and interleukin-6. Shock 7:1-8, 1997.
  17. Rameshwar P, Chang VT, Thacker UF, Gascón P. Systemic transforming growth factor-beta in patients with bone marrow fibrosis. Pathological implications. Am. J. Hematol. 59:133-42, 1998.
  18. Quinlan Jr. D, Rameshwar P, Qian J, Maloof PB, Mohr AM, Hauser CJ, Livingston DH. Effect of hypoxia on the hematopoietic and immune modulator preprotachykinin-1. Archives of Surg. 133:1328-34, 1998.
  19. Quinlan Jr. D, Rameshwar P, Hauser C, Livingston D. (1998) The effect of hypoxia on bone marrow myeloid and erythroid progenitor cells. Surg. Forum 49:35-37.
  20. Rameshwar P, Smith I, Ende N, Batarseh HE, Ponzio NM. Endogenous hematopoietic reconstitution induced by human umbilical cord blood cells in immunocompromised mice: Implications for adoptive therapy. Exp. Hematol. 27:176-85, 1998.
  21. Yao R, Rameshwar P, Donnelly RJ, Siegel A. Neurokinin-1 expression and colocalization with glutamate and GABA in the hypothalamus of the cat. Mol. BrainRes. 71:149-58, 1999.
  22. Pappas PJ, You R, Rameshwar P, Gorti R, DeFouw DO, Phillips CK, Padberg Jr. FT, Silva Jr. MB, Simonian GT, Hobson II RW, Duran WN. (1999) Dermal tissue fibrosis in patients with chronic venous insufficiency is associated with increased transforming growth factor-b1 gene expression and protein production. J. Vasc. Surg. 30:1129-42.
  23. Singh D, Joshi DD, Hameed M, Qian J, Gascón P, Maloof PB, Mosenthal A, Rameshwar P. Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells. Implications for bone marrow metastasis. Proc. Nat’l Acad. Sci. USA (Track II/Direct submission) 97:388-93, 2000.
  24. Taneja R, Rameshwar P, Upperman J, Wang MT, Livingston DH. Effects of hypoxia on granulocytic-monocytic progenitors in rats. Role of bone marrow stroma. Am. J. Hematol. 64:20-25, 2000.
  25. Rameshwar P, Narayanan R, Qian J, Denny TN, Colon C, Gascón P. NF-kB as a central mediator in the induction of TGF-b in monocytes from patients with idiopathic myelofibrosis: An inflammatory response beyond the realm of homeostasis. J. Immunol. 165:2271-7, 2000.
  26. Gascón P, Qian J, Joshi DD, Teli T, Haider A, Rameshwar P.Effects of Preprotachykinin-I peptides on hematopoietic homeostasis. A role for bone marrow (BM) endopeptidases. Ann.N.Y.Acad. Sci. 917:416-23, 2000.
  27. Anjaria DJ, Rameshwar P, Xu Da-Zhong, Adams CA, Forsythe RM, Sambol JT, Hauser CJ, Deitch EA, Livingston DH. Hematopoietic failure following hemorrhagic shock is partially mediated by the gut. Surg. Forum 51:169-71, 2000.

2001- 2003:

  1. Maloof PB, Joshi DD, Qian J, Gascón P, Singh D, Rameshwar P. Induction of Preprotachykinin-I and Neurokinin-1 by adrenocorticotropin and prolactin. Implication for neuroendocrine-immune-hematopoietic axis. J. Neuroimmunol. 112:188-96 (PRF/LITDB, accession number 2707865), 2001.
  2. Wu CJ, Livingston DH, Hauser CJ, Deitch EA, Rameshwar P. Trauma inhibits BFU-E and CFU-GM colony growth through the production of TGF-b1 by bone marrow stroma. Ann. Surg. 234:224-32, 2001.
  3. Qian J, Yehia G, Molina C, Fernandes A, Donnelly RJ, Anjaria DA, Gascón P, Rameshwar P. Cloning of human preprotachykinin-I promoter and the role of cyclic adenosine 5΄-monophospage response elements in its expression by IL-1 and stem cell factor. J. Immunol. 166:2553-61, 2001.
  4. Rameshwar P, Joshi DD, Yadav P, Gascón P, Qian J, Chang VT, Anjaria A, Harrison JS, Xiaosong S. Mimicry between neurokinin-1 and fibronectin may explain the transport and stability of increased substance P-immunoreactivity in patients with bone marrow fibrosis. Blood 97:3025-31, 2001.
  5. Yao R, Rameshwar P, Gregg T, Siegel A. Co-localization of NK-1 receptor with glutamate immunopositivity in cat hypothalamic neurons by the combination of insitu hybridization and immunohistochemistry. Brain Res. Protocols 7:154-61, 2001.
  6. Anjaria DJ, Rameshwar P, Deitch EA, Xu Da-Zhong, Adams CA, Forsythe RM, Sambol JT, Hauser CJ, Livingston DH. Hematopoietic failure following hemorrhagic shock is mediated partially through mesenteric lymph. Crit. CareMed. 29:1780-5, 2001.
  7. Joshi DD, Dang A, Yadav P, Qian J, Bandari PS, Chen K, Donnelly R, Castro T, Gascón P, Haider A, Rameshwar P. Negative feedback on the effects of stem cell factor on hematopoiesis is partly mediated through neutral endopeptidase activity on substance P: A combined functional and proteomic study. Blood 98:2697-706, 2001.
  8. Qian J, Ramroop K, McLeod A, Bandari P, Livingston DH, Harrison JS, Rameshwar P. Induction of hypoxia-inducible factor-1a and caspase-3 in hypoxic bone marrow stroma is negatively regulated by the delayed production of substance P. J. Immunol. 167:4600-8, 2001.
  9. Rameshwar P, Zhu G, Donnelly RJ, Qian J, Ge H, Goldstein KR, Denny TN, Gascón P. The dynamics of bone marrow stromal cells in the proliferation of multipotent hematopoietic progenitors by substance P: An understanding of the effects of a neurotransmitter on the differentiating hematopoietic stem cell. J. Neuroimmunol. 121:22-31, 2001.
  10. Bandari, PS, Qian J, Yehia G, Seegopaul HP, Harrison JS, Gascon P, Fernandes H, Rameshwar P. Differences in the expression of neurokinin receptor in neural and bone marrow mesenchymal cells: Implications for neuronal expansion from bone marrow cells. Neuropeptides 36:13-21, 2002.
  11. Rameshwar P, Gascon P, Bandari PS, Joshi DD, Fernandes A, Dang A.  Structural similarity between the bone marrow extracellular matrix protein and neurokinin 1 could be the limiting factor in the hematopoietic effects of substance P. Can. J. Pharmacol. Physiol. 80:475-81, 2002.
  12. Goldstein KR, Bhatt R, Barton BE, Zalcman S, Rameshwar P, Siegel A. (2002) Effects of hemispheric lateralization and site specificity on immune alterations induced by kindled temporal lobe seizures. Brain Behav. Immunity 16:706-719.
  13. Rameshwar P, Gascon P, Oh HS, Denny T, Zhu G, Ganea D. Vasoactive Intestinal Peptide (VIP) inhibits the proliferation of bone marrow progenitors through the VPAC1 receptor. Exp.Hematol. 30:1001-9, 2002.
  14. Song X, Mohr AM, Rameshwar P, Anjaria D, Fekete Z, Heary RF, Hauser CJ, Livingston DH. Delay in the differentiation of HL-60 cells following exposure to hypoxia. J Surg Research 108:243-249, 2002.
  15. Harrison JS, Rameshwar P, Chang V, Bandari P. Oxygen saturation in the bone marrow of healthy volunteers. Blood 99:394, 2002. (LETTER)
  16. Bandari PS, Qian J, Yehia G, Joshi DD, Maloof PB, Potian J, Oh HS, Gascon P, Harrison JS, Rameshwar P. Hematopoietic Growth Factor Inducible Neurokinin-1 type (HGFIN) gene: A transmembrane protein that is similar to neurokinin-1 interacts with substance P. Regulatory Peptides 111:169-78, 2003.
  17. Bandari PS, Qian J, Oh HS, Potian JA, Yehia G, Harrison JS, Rameshwar P. Crosstalk between neurokinin receptors is relevant to hematopoietic regulation: Cloning and characterization of neurokinin-2 promoter.J. Neuroimmunol. 138:65-75, 2003.
  18. Bhatt R, Rameshwar P, Goldstein K, Siegel A. Effects of kindled seizures upon hematopoiesis in rats. Epilepsy Res 54:209-219, 2003.
  19. Rameshwar P, Ramkissoon SH, Sundararajan S, Gascón P. Defect in the lymphoid compartment might account for CD8+mediaed effects in the pathophysiology of Pure Red Cell Aplasia. ClinImmunol 108:248-56, 2003.
  20. Livingston DH, Anjaria D, Wu J, Hauser CJ, Chang V, Deitch EA, Rameshwar P. Bone marrow failure following severe injury in man. Annals of Surg 238:748-53, 2003.
  21. Potian JA, Aviv H, Ponzio NM, Harrison JS, Rameshwar P.Veto-like activity of mesenchymal stem cells (MSC): Functional discrimination between cellular responses to alloantigen and recall antigens. JImmunol 171:3426-34, 2003.

2004-2006:

  1. Rao G, Patel PS, Idler SP, Maloof P, Gascon P, Potian JA, Rameshwar P. Facilitating role of preprotachykinin-I gene in the integration of breast cancer cells within the stromal compartment of the bone marrow: A model of early cancer progression.  Cancer Res 64: 2874-81, 2004.PMID: 15087406
  2. Bhatt R, Bhatt S, Rameshwar P, Siegel A. Amygdaloid kindled seizures induce weight gain in rats: Dominance of the left hemisphere. PhysiolBehav 82:581-7, 2004.
  3. Oh HS, Moharita A, Potian JG, Whitehead IP, Livingston JC, Castro TA, Patel PS,Rameshwar P. Bone marrow stroma influences TGF-b production in breast cancer cells to regulate c-myc activation of the preprotachykinin-I gene in breast cancer cells.  Cancer Res 64:6327-36, 2004.PMID: 15342422
  4. Antoniou ES, Sund S, Homsi EN, Challenger L, Rameshwar P. A theoretical simulation of hematopoietic stem cells during oxygen fluctuations: Prediction of bone marrow responses during hemorrhagic shock. Shock 22:415-22, 2004.
  5. Fonseca RB, Mohr AM, Wang L, Clinton E, Sifri ZC, Rameshwar P, Livingston DH. (2004) Adrenergic modulation of erythropoiesis following severe injury is mediated through bone marrow stroma. SurgInfect 5:385-93.
  6. Cho KJ, Trzaska KA, Greco SJ, McArdle J, Wang FS, Ye JH, Rameshwar P. Neurons derived from human mesenchymal stem cells show synaptic transmission and can be induced to produce the neurotransmitter substance P by interleukin-1a. Stem Cells 23:383-91, 2005.
  7. Metz RL, Yehia G, Fernandes H, Donnelly R, Rameshwar P. Cloning and characterization of the 5¢ flanking region of the HGFIN gene indicate a cooperative role among p53 and cytokine-mediated transcription factors: Relevance to cell cycle regulation. Cell Cycle 4:78-85, 2005.
  8. Mukerji I, Ramkissoon SH, Reddy KKR, Rameshwar P. Autocrine proliferation of neuroblastoma cells is partly mediated through neurokinin receptors: Relevance to bone metastasis. J Neuro-Oncol 71:91-8, 2005.
  9. Corcoran K, Patel PS, Rameshwar P. An in vitro method to select malignant cells from surgical biopsies of breast cancer patients. BiolProc Online 7:7-15, 2005.
  10. Kang HS, Habib M, Chan J, Abavana C, Potian JA, Ponzio NM, Rameshwar P. A paradoxical role for IFNγ in the immune properties of mesenchymal stem cells during viral challenge. ExpHematol 33:796-803, 2005.
  11. Bhatt R, Bhatt S, Rameshwar P, Siegel A. Long term kindled seizures induce alterations in hematopoietic functions: Role of serum leptin. Epilepsy Res 65:169-78, 2005.
  12. Patel H, Ramkissoon SH, Patel PS, Rameshwar P. Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-I peptides. ProcNatlAcadSci USA (Track II) 102:17436-41, 2005.PMCID: PMC1297665
  13. Fonseca RB, Mohr AM, Wang L, Sifri ZC, Rameshwar P, Livingston DH. The impact of a hypercatecholamine state on erythropoiesis following severe injury and the role of IL-6. J Trauma 59:884-90, 2005.
  14. Castro TA, Cohen MC, Rameshwar P. The expression of neurokinin-1 and preprotachykinin-1 in breast cancer cells depends on the relative degree of invasive and metastatic potential. ClinExpMetastasis 22:621-8, 2005.
  15. Sifri ZC, Kaiser VL, Ananthakrishnan P, Wang L, Mohr AM, Hauser CJ, Rameshwar P, Deitch EA, Livingston DH. Bone marrow failure in male rats following trauma/hemorrhagic shock (t/hs) is mediated by mesenteric lymph and modulated by castration. Shock 25:12-16, 2006.
  16. Vishalakumar S, Patel H, Moharita AL, Harrison JS, Rameshwar P. The anti-proliferative effect of neurokinin-A on hematopoietic progenitor cells is partly mediated by p53 activating the 5¢ flanking region of neurokinin-2 receptor. Cell Signaling 18:422-32, 2006.
  17. Bhatt R, Bhatt S, Hameed M, Rameshwar P, Siegel A. (2006) Amygdaloid kindled seizures can induce functional and pathological changes in thymus of rat: Role of the sympathetic nervous system. Neurobiol of Disease21:127-37.
  18. Harrison JS, Corcoran KE, Joshi D, Sophacleus C, Rameshwar P. Peripheral monocytes and CD4+ cells are potential sources for increased circulating levels of TGF-b and Substance P in autoimmune myelofibrosis. Am J Hematol 81:51-8, 2006.
  19. Chan JL, Tang KC, Patel AP, Bonilla LM, Pierobon N, Ponzio NM, Rameshwar P. Antigen presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-γ. Blood 107:4817-24, 2006.
  20. Singh AS, Caplan A, Corcoran KE, Fernandez JS, Preziosi M, Rameshwar P. Oncogenic and Metastatic Properties of Preprotachykinin-I and Neurokinin-1 genes. Vascular Pharmacol 45:235-42, 2006.
  21. Moharita AL, Taborga M, Corcoran KE, Bryan M, Patel PS, Rameshwar P.  SDF-1a regulation in breast cancer cells contacting bone marrow stroma is critical for normal hematopoiesis. Blood 108:3245-52, 2006.

2007-2009:

  1. Corcoran KE, Patel N, Rameshwar P. Stromal Derived Growth Factor-1a: Another mediator in neural-emerging immune system through Tac1 expression in bone marrow stromal cells. J Immunol 178:2075-82, 2007.
  2. Smirnov SV, Harbacheuski R, Lewis-Antes A, Zhu H, Rameshwar P, Kotenko SV.Bone-marrow-derived mesenchymal stem cells as a target for cytomegalovirus infection: Implications for hematopoiesis, self-renewal and differentiation potential. Virology 360:6-16, 2007.
  3. Ramkissoon SH, Patel PS, Taborga M, Rameshwar P. NFκB is central to the expression of truncated neurokinin-1 receptor in breast cancer: Implication for breast cancer cell quiescence within bone marrow stroma. Cancer Res 67:1653-59, 2007.PMID: 17308106
  4. Sifri ZC, Cohen D, Ananthakrishnan P, Wang L, Kaiser VL, Mohr AM, Hauser CJ, Rameshwar P, Deitch EA, Livingston DH. (2007) Sex hormones affect bone marrow dysfunction after trauma and hemorrhagic shock. Crit Care Med 35:864-69.
  5. Corcoran KE, Rameshwar P.(2007)NFκB and not receptor desensitization accounts for the repressor effects of high SDF-1a levels onTac1 expression in non-tumorigenic breast cells. Mol Cancer Res 5:373-81.
  6. Greco SJ, Zhou C, Ye J-H, Rameshwar P. An interdisciplinary approach and characterization of neuronal cells transdifferentiated from human mesenchymal stem cells. Stem Cells and Dev 16:811-826, 2007.
  7. Greco SJ, Rameshwar P. Enhancing effect of IL-1a on neurogenesis from adult human mesenchymal stem cells: Implication for inflammatory mediators in regenerative medicine. J Immunol 179:3342-50, 2007.
  8. Trzaska KA, Kuzhikandathil EV, Rameshwar P. (2007) Specification of a dopaminergic phenotype from adult human mesenchymal stem cells. Stem Cells 25:2797-808.
  9. Greco SJ, Rameshwar P. MiRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells. ProcNatlAcadSci USA (Track II) 104:15484-9. 2007.
  10. Greco SJ, Smirnov SV, Murthy RG, Rameshwar P.Synergy between RE-1 silencer of transcription and NFκB in the repression of the neurotransmitter gene Tac1 in human mesenchymal stem cells. J BiolChem 282:282:30039-50, 2007.
  11. Greco SJ, Liu K, Rameshwar P. Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells. Stem Cells 25:3143-54, 2007. (Discussed by Josh P. Roberts, The Scientist, 10th Oct, 2007).
  12. Metz R, Patel PS, Hameed M, Bryan M, Rameshwar P. Molecular analyses on the metastatic role of human HGFIN/nmb in breast cancer. Breast Cancer Res 9:R58, 2007. 
  13. PatelN, Castillo M, Rameshwar P. An in vitro method to study the effects of hematopoietic regulators during immune and blood cell development. Biol Procedures Online 9:56-64, 2007.
  14. Murthy RG, Greco SJ, Taborga M, Patel N, Rameshwar P. Tac1 regulation by RNA-binding protein and miRNA in bone marrow stroma: Implication for hematopoietic activity. Brain Behav Immunity 22:442-50, 2008.
  15. Tang KC, Trzaska KA, Smirnov SV,Kotenko SV, Schwander SK, Ellner JJ, Rameshwar P. Down regulation of MHC-II in mesenchymal stem cells at high IFNγ can be partly explained by cytoplasmic retention of CIITA. J Immunol180:1826-33, 2008.
  16. Corcoran KE, Malhotra A, Molina CA, Rameshwar P. SDF-1ainducesanon-canonicalpathwaytoactivatetheendocrine-linkedTac1geneinnon-tumorigenicbreastcells. J MolEndocrinol 40:113-123, 2008.
  17. Castillo MD, Trzaska KA, Greco SJ, Ponzio NM, Rameshwar P. Immunostimulatory effects of mesenchymal stem cell-derived neurons: Implications for stem cell therapy in allogeneic transplantations. Clin Translational Sci 1:27-34, 2008. (Article discussed in Nature Reports Stem Cells, Coombs A. 2008, Questioning the self cell, 5 June 2008 | doi:10.1038/stemcells.2008.86).
  18. Corcoran KE, Trzaska KA, Fernandes H, Bryan M, Taborga M, Srinivas V, Packman K, Patel PS, RameshwarP. Mesenchymal stem cells in early entry of breast cancer into bone marrow. PlosONE 3:e2563, 2008. (Article highlighted in Medwirenews, By Andrew Czyzewski, 6/30/08)PMCID: PMC2430536
  19. Trzaska KA, Reddy BY, Munoz JL, Li K-Y, Ye J-H, Rameshwar P. Loss of RE-1 Silencing Factor in mesenchymal stem cell-derived dopamine progenitors induces functional maturity. Mol Cellular Neurosci 39:285-290, 2008.
  20. Ricardo M, Trzaska KA, Rameshwar P. Neurokinin-A inhibits cell cycle activators in K562 cells and activates Smad 4 through a non-canonical pathway: A novel method in Neural-Hematopoietic Axis. J Neuroimmunol 204:85-91, 2008.
  21. Greco S, Rameshwar P. A method to generate human mesenchymal stem cell-derived neurons which express and are excited by multiple neurotransmitters. Biol Procedure 10:90-101, 2008.
  22. Liu K, Wong EW, Schutzer SE, Connell ND, Upadhyay A, Bryan M, Rameshwar P. Non-canonical effects of anthrax toxins on hematopoiesis: implications for vaccine development. J Cellular Mol Med 13:1907-1919, 2009.
  23. Reddy BY, Greco SJ, Patel PS, Trzaska KA, Rameshwar P. RE-1 silencing transcription factor shows tumor suppressor functions and negatively regulates the oncogenic TAC1 in breast cancer cells. ProcNatlAcadSci USA (Track II) 106:4408-13, 2009.PMCID:PMC 2647978
  24. Trzaska KA, King CC, Le K-Y, Kuzhikandathil EV, Nowycky MC, Ye J-H, Rameshwar P. Brain derived neurotrophic factor facilitates maturation of mesenchymal stem cell-derived dopamine progenitors to functional neurons. J Neurochem 110:1058-1069, 2009.
  25. Cho J, Rameshwar P, Sadoshima J. Distinct roles of GSK-3a and GSK-3βin mediating cardiomyocyte differentiation in murine bone marrowderived mesenchymal stem cells. J BiolChem284:36647-58, 2009.

2010-2012:

  1. Patel SA, Meyer J, Greco SJ, Corcoran KE, Bryan M, Rameshwar P. Mesenchymal stem cells protect breast cancer cells through regulatory T cells: Role of mesenchymal stem cell-derived TGF-β. J Immunol 184:5885 -5894, 2010.
  2. Penn A, Mohr AM, Shah SG, Sifri ZC, Kaiser VL, Rameshwar P, Livingston DH. Dose-response relationship between norepinephrine and erythropoiesis: Evidence for a critical threshold.J Surg Res 163:e85-90, 2010.
  3. Beiermeister KA, Keck BM, Sifri ZC, Elhassan IO, Hannoush EJ, Alzate WD, Rameshwar P, Livingston DH, Mohr AM. Hematopoietic progenitor cell mobilization is mediated through beta-2 and beta-3 receptors after injury. J Trauma 69:338-43, 2010.
  4. Lim PK, Bliss SA, Patel SA, Taborga M,Dave MA, Gregory LA, Greco SJ, Bryan M, Patel PS, Rameshwar P. Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. Cancer Res 71:1550-1560, 2011.PMID: 21343399
  5. Mohr AM, Elhassan IO, Hannoush EJ, Sifri ZC, Offin MD, Alzate WD, Rameshwar P, Livingston DH. Does Beta blockade post-injury prevent bone marrow suppression? J Trauma 70:1043-1050, 2011.
  6. Greco SJ, Patel SA, Bryan M, Pliner LF, Banerjee D, Rameshwar P. AMD3100-mediated production of interleukin-1 from mesenchymal stem cells is key to chemosensitivity of breast cancer cells. Am J Cancer Res 1:701-715, 2011. PMCID: PMC3195931
  7. Elhassan IO, Hannoush EJ, Sifri ZC, Jones E, Alzate WD, Rameshwar P, Livingston DH, Mohr AM. Beta-Blockade prevents hematopoietic progenitor cell suppression after hemorrhagic shock. SurgInfect 12:273-278, 2011.
  8. Baranski GM, Offin MD, Sifri ZC, Elhassan IO, Hannoush EJ, Alzate WD, Rameshwar P, Livingston DH, Mohr AM. β-Blockade protection of bone marrow following trauma: The role of G-CSF. J SurgRes 170:325-31, 2011.
  9. Rameshwar P, Wong EW, Connell ND. Effects by anthrax toxins on hematopoiesis: A key role for cytokines as mediators. Cytokines 57:143-149, 2012.
  10. Patel N, Klassert TE, Greco SJ, Patel SA, Munoz JL, Reddy BY, Bryan M, Campbell N, Kokorina N, Sabaawy HE, Rameshwar P. Developmental regulation of TAC1 in peptidergic-induced human mesenchymal stem cells: Implication for spinal cord injury in zebrafish. Stem Cell Dev 21:308-320, 2012.
  11. Kapoor S, Patel SA, Kartan S, Axelrod D, Capitle E, Rameshwar P. Tolerance-like mediated suppression by mesenchymal stem cells in dust mite allergic asthma. J Allergy ClinImmunol 129:1094-1101, 2012. (Cited and discussed on World Biomed Frontiers, http://biomedfrontiers.org/allergy-2013-11-30/, 2013-September – November)
  12. Luistro LL, Rosinski JA, Bian H, Bishayee S, Rameshwar P, Ponzio NM, Ritland SR. Development and characterization of a preclinical ovarian carcinoma model to investigate the mechanism of acquired resistance to trastuzumab. Intl J Oncol41:639-651, 2012.
  13. Jessian L. Munoz, Greco SG, Patel SA, Sherman LS, Bhatt S, Bhatt RS, Shrensel JA, Guan Y-Z, Xie G, Ye J-H, Rameshwar P, Siegel A. Feline bone marrow-derived mesenchymal stromal cells (MSCs) show similar phenotype and functions with regards to neuronal differentiation as human MSCs. Differentiation 84:214-22, 2012.
  14. Navarro P, Ramkissoon SH, Shah S, Park JM, Murthy RG, Patel SA, Greco SJ, Rameshwar P. An indirect role for the oncomir-519b in the expression of truncated neurokinin-1 in breast cancer cells. ExpCell Res 318:2604-2615, 2012.PMCID: PMC3645290
  15. Patel SA, Ramkissoon SH, Bryan M, Pliner LF, Dontu G, Patel PS, Amiri S, Pine SR, Rameshwar P. Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy. ScientificReports2, 906, 2012; DOI:10.1038/srep00906.PMCID:PMC3510468

2013-

  1. Chang VT, Yook C, Rameshwar P. Synergism betweenfibronectin and TGF-β1 in the production of substance P in monocytes of patients with myelofibrosis. Leuk Lymphoma 54:631-638, 2013.
  2. Park JM, Munoz JL, Won BW, Bliss SA, Greco SJ, Patel SA, Kandouz M, Rameshwar P. Exogenous CXCL12 activates protein kinase C to phosphorylate. Cancer Lett 331:84-91, 2013.PMID: 23262036
  3. Hoover DJ, Zhu V, Chen R, Briley K, Rameshwar P, Cohen S, Coffman FD. Expression of the Chitinase Family Glycoprotein YKL-40 in Undifferentiated, Differentiated and Trans-Differentiated mesenchymal stem cells. PloS One 8:e62491, 2013.
  4. Rodgerson DO, Harris A, Giampapa VC, Greco SJ, O'Neill D, Rameshwar P. Novel Regenerative Solutions Induce Rapid Adipogenic Differentiation of Mesenchymal Stem Cells with No Evidence of Transformation or Osteogenic Differentiation. Adv Stem CellsArticle ID 716906, DOI: 10.5171/2013. 716906, 2013.
  5. Morelli SS, Rameshwar P, Goldsmith LT. Experimental Evidence for Bone Marrow as a Source of Nonhematopoietic Endometrial Stromal and Epithelial Compartment Cells in a Murine Model Biol of Reprod89:1-7, 2013.
  6. Munoz JL, Bliss SA,Greco SJ, Ramkissoon SH, Ligon KL, Rameshwar P. Delivery of functional anti-miRNA-9 by mesenchymal stem cells-derived exosomes to Glioblastoma Multiforme conferred chemosensitivity. MolTher - Nucleic Acids2:e126, 2013.(featured in Mesenchymal Stem Cell news 5.3, Oct 8, 2013)PMID: 24084846
  7. Desai MB, Gavrilova T, Liu J, Patel SA, Kartan S, Greco SJ, Capitle E, Rameshwar P. Pollen-inducedantigen presentation by mesenchymal stem cells and T-cells from allergic rhinitis.ClinTranslImmunol2: e7, 2013 (doi:10.1038/cti.2013.9).
  8. Baranski GM, Pasupuleti LV, Sifri ZC, Cook KM, Alzate WD, Rameshwar P, Livingston DH, Mohr AM. Beta blockade protection of bone marrow following injury: A critical link between heart rate and immunomodulation. J Bone Marrow Res 1:124, 2013 (doi:10.4172/2329-8820.1000124)
  9. Marlow R,Honeth G, Lombardi S, Cariati M, Hessey S, Pipili A, Mariotti V, Buchupalli B, Foster K, Bonnet D, Grigoriadis A, Rameshwar P, Purushotham A, Tutt A, Dontu G. A novel model of dormancy for bone metastatic breast cancer cells. Cancer Res73; 6886–99, 2013.
  10. Sarker MMH, Zhou MC, Rameshwar P, Hanover JA. Functions and roles of a protein associated factor. Cell Biochem and Biophysics 68: 577-82, 2014.
  11. MunozJL, Rodriguez-Cruz V, GrecoSJ, RamkissoonSH,LigonKL,RameshwarP.Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43. Cell Death Dis5:e1145, 2014.
  12. Sarker MMH, Zhou MC, Rameshwar P, Hanover JA. Functions and roles of proteins on diabetes.Prog BiophysicsMolBiol114:2-7, 2014.
  13. Patel SA, Dave MA, Bliss SA,Giec-Ujda AB, Bryan M, Pliner LF, Rameshwar P. Treg/Th17 polarization by distinct subsets of breast cancer cells is dictated by the interaction with mesenchymal stem cells.J Cancer Stem Cell Res2:e1003, 2014.
  14. Munoz JL, Rodriguez-Cruz V, Greco SJ, Nagula V, Scotto KW,Rameshwar P.Temozolomide induces the production of epidermal growth factor to regulate MDR1 expression in glioblastoma cells.Mol Cell Ther13:2399-2411, 2014.
  15. Munoz JL, Rodriguez-Cruz V, Ramkissoon SH, Ligon KL, Greco SJ, Rameshwar P.Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level. Oncotarget (In press).

Editorials/Commentaries/Perspectives/Short Communication:

  1. Rameshwar P. (2008) IFNγ and B7-H1 in the immunology of mesenchymal stem cells. Cell Res 18:805-806. (EDITORIAL)
  2. Rameshwar P. (2008) Is substance P central to the biology of acute lymphoblastic leukemia? Leuk Res 32:3-4. (EDITORIAL)
  3. Rameshwar P. (2009) Casting doubt on the safety of `off-the-shelf' mesenchymal stem cells for cell therapy. Mol Therapy 7:216-218. (COMMENTARY).
  4. Rameshwar P. (2009) Microenvironment at tissue injury, a key focus for efficient stem cell therapy: A discussion of Mesenchymal Stem Cells. World J Stem Cells 1:3-7. (EDITORIAL)
  5. Rameshwar P. (2010) Breast cancer cell dormancy in bone marrow: Potential therapeutic targets within the marrow microenvironment. ExpertRev AntiCancer Therapy10:129-132. (EDITORIAL)
  6. Rameshwar P. (2011) Post-identification of Cancer Stem Cell: Ethical and Scientific Dilemmas in Therapeutic Development? J Stem Cell Therdoi: 10.4172/2157-7633.1000e101. (EDITORIAL)
  7. Rameshwar P. (2012) Implications for breast cancer dormancy in other areas of medicine. BreastCancer: Targets and Therapy4:193-195. (EDITORIAL)
  8. Rameshwar P. (2012)Would cancer stem cells affect the future investment in stem cell therapy?2:26-29. (EDITORIAL)
  9. Rameshwar P. (2013) Mesenchymal Stem Cells can be a Conduit for the Delivery of Therapeutic MicroRNA. Stem Cell Res Ther 3:1. (EDITORIAL)
  10. Bhartiya D, Boheler K, Rameshwar P. (2013) Multipotent to Pluripotent Properties of Adult Stem Cells. Stem Cell Intl2013:813780.(EDITORIAL)
  11. Bliss SA, Greco SJ, Rameshwar P. (2014) Hierarchy of breast cancer cells: Key to reverse dormancy for therapeutic intervention. Stem Cells Transl Med3:782-786. (PERSPECTIVE)
  12. Rameshwar P. (2014) Future challenges to target cancer stem cells. Enliven: Challenges in Cancer 2014;1:e2.(SHORT COMMUNICATION)
  13. Singh SR, Tan M, Rameshwar P. (2015) Cancer metabolism: Targeting metabolic pathways in cancer therapy. Cancer Let356:147-148(EDITORIAL)

Books,Monographs and Chapters

Book Edited:

  1. Cancer Metastasis (2010). Transworld Research Network, Kerala, India.
  2. MicroRNA in development and in the progression of cancer (2013). Co-editor, Shree Ram Singh, Springer, USA.

Chapters:

  1. Rameshwar P, Gascón P. Neural regulation of hematopoiesis by the tachykinins. Implications for a "fine-tuned" hematopoietic regulation. In Molecular Biology of Hematopoiesis (N.G. Abraham, S. Asano, G. Brittinger, and R. Shadduck, eds). p. 463-470, Plenum Press, NY, 1996.
  2. Qian J, Haider A, Teli T, Tuan T, Gascón P, Rameshwar P. Effects of SP(1-4) on cobblestone-forming cells. Implications for endopeptidases as hematopoietic regulators. In Proceedings of the 10th Int’l Congress of Immunol. (G.P. Talwar, I. Nath, N.K. Ganguly, K.V.S. Rao, eds.), p. 575-581,MonduzziEditore, Bologna, Italy, 1998.
  3. Keller SE, Schleifer SJ, Bartlett JA, Shiflett SC, Rameshwar P. Stress, Depression, Immunity, and Health. In Psychoneuroimmunology: Stress, Mental Disorders and Health. (K. Goodkin, A.P. Visser, eds.) p. 1-25, Am Psych Press, Inc., Washington, DC, 1999.
  4. Bandari PS, Oh HS, Yook C, Potian JA, Fernandes NF, Chang VT, Rameshwar P. Neurokinin-1 as a potential target for treatment of myelofibrosis. In Proceedings of the 7th Annual Meeting of the European Haematology Association. p. 243-248, MonduzziEditore, Bologna, Florence, Italy, 2002.
  5. Gascon P, Rameshwar P. Transforming growth factor beta-1 (TGF-b1) in myelofibrosis. In Molecular Basis of Chronic Myeloproliferative Disorders. (P.E. Petrides, H.L. Pahl, eds.), p. 147-155, Springer-Verlag, Berlin, 2004.
  6. Preziosi M, Arun S. Singh AS, Corcoran KE, Wong E, Ramkissoon SH, Mukerji I, Rameshwar P. Chapter 5, Parallels among subsets of breast cancer in bone marrow, leukemia and hematopoietic stem cells. In Res Adv in Cancer, p. 139-155, Global Res Network, 2005.
  7. Rameshwar P. Chapter 5, Mesenchymal Stem Cells as bone marrow `gate-keepers': Implications for hematological disorder. In Stem Cell Research Advances; Ed. Lydia P. Davenport; p.137-147, Nova Publishers, Hauppauge, NY, 2007.
  8. Trzaska KA, Greco SJ, Moore L, Rameshwar P. Part II/Chapter 8, Mesenchymal Stem Cells and Transdifferentiated Neurons in Crosstalk with the Tissue Microenvironment: Implications for Translational Science. In Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging, p.215-230, Oxford Univ Press (Ed, Maiese K), 2008.
  9. Rameshwar P, Bardeguez A.Part I/Chapter 5, Molecular Basis of Cytokine Function. InThe Neuroimmunological Basis of Behavior and Mental Disorders,p.59-70, Springer-Verlag  (Eds, Siegel A &Zalcman S), 2008.
  10. Navarro P, Castillo M, Rameshwar P. Chapter 3, Immune threat to neurogenesis from human adult mesenchymal stem cells. In Stem Cell Applications in Diseases; Ed. Burnsides WB &Ellsley RH; Nova Publishers, Hauppauge, NY, 2008.
  11. King C, Patel S, Arinzeh-Livingston T, Rameshwar P. Chapter 17, Dual roles of mesenchymal stem cells in spinal cord injury: Cell replacement therapy and as a model system to understand axonal repair. In Perspectives in Stem Cells: From tools for studying mechanisms of neuronal differentiation to towards therapy. p.271-284, Springer Dordrecht Heidelberg London New York (Ed, Hennig U), 2009.
  12. Lim P, Patel SA, Rameshwar P. Chapter 17, Effective tissue repair and immunomodulation by mesenchymal stem cells within a milieu of cytokines. In Stem Cell-Based Tissue Repair,p.338-57, Royal Society of Chemistry Publishing, Cambridge, UK (Eds, Gorodetsky R &Schäfer R), 2010.
  13. Patel SA, Rameshwar P. Co-existence of hematopoietic stem cells and cancer cells during cancer quiescence. In Stem Cells: Organogenesis and Cancer. p.139-51, Transworld Res Network, Kerala, India (Eds. Singh SR, Mishra PK, Hou SX), 2010.
  14. Trzaska KA, Ramkissoon S, Harrison JS, Rameshwar P. Chapter 4, The Biology of Metastatic Neuroblastoma. In Cancer Metastasis.p.39-52, (Ed, P.Rameshwar), Transworld Res Network, Kerala, India. 2010.
  15. Murthy RG, Fernandez J, Rameshwar P. Chapter 3, Molecular and Cellular Events Preceding Bone Metastasis of Breast Cancer. In Cancer Metastasis. p. 29-37, (Ed, P.Rameshwar), Transworld Res Network, Kerala, India. 2010.
  16. Metz RL, Rameshwar P. Chapter 5, HGFIN/Osteoactivin: A developing link in breast cancer biology. In Cancer Metastasis,p.53-62, (Ed, P. Rameshwar), Transworld Res Network, Kerala, India. 2010.
  17. Homsi E, Grumm K, Rameshwar P.Chapter 11,Predictive development of cancer as stem cell therapy approaches the bedside. In Cancer Metastasis, p. 116-125, (Ed, P. Rameshwar), Transworld Res Network, Kerala, India. 2010.
  18. Trzaska KA, Rameshwar P. Chapter 22, Dopaminergic neuronal differentiation protocol for human mesenchymal stem cells.In Methods MolBiol, (Vemuri M,  Chase LG, Rao MS, Eds), vol698, p. 295-303, Human Press, 2011.
  19. Munoz JL, Patel SA, Lim PK, Giec A, Silverio KA, Pliner LF, Rameshwar P. Potential Confounds in Stem Cell Therapy: A Case Study of Mesenchymal Stem Cells and Cancer Stem Cells. InAdult Stem Cell Standardization (Ed, P. DiNardo), p. 223-238, River Publisher, Aalborg, Denmark, 2011. 
  20. Greco SJ, Patel SA, Rameshwar P. A reporter assay to detect transfer and targeting of miRNAs in Stem Cell-Breast Cancer Co-cultures. In Somatic Stem Cells (Ed. Singh, Shree Ram) Methods and Protocols Series, Methods Mol Biol. Humana Press, Vol 879, p. 195-201, 2012.
  21. Greco SJ, Rameshwar P. Stem cell utility in anti-aging medicine: Focus on the tissue microenvironment. In The principles and practice of anti-aging medicine for the clinical physician. (Ed. Vincent C. Giampapa), River Publishers, Aalborg, Denmark, 2012.
  22. King C, Patel SA, Rameshwar P. Chapter 76, The role of human postnatal bone marrow-derived mesenchymal stem cells and their importance in growth, spinal cord injury and other neurodegenerative disorders. In Handbook of growth and growth monitoring in health and disease. Vol. 1, p. 1273-89, (Ed. Victor R. Preddy), Springer, 2012.
  23. Rameshwar P. Chapter 1, Current thoughts on the therapeutic potential of stem cell.InMethods MolBiol (Somatic stem cells: methods and protocols) vol.879, p. 3-26, (Ed. Shree Singh), Humana Press, 2012.
  24. Greco SJ, Patel SA, Rameshwar P. Chapter 13, A reporter assay to detect transfer and targeting of miRNAs in stem cell-breast cancer co-cultures, InMethods MolBiol (Somatic stem cells: methods and protocols) vol.879, p. 3-26, (Ed. Shree Singh), Humana Press, 2012.
  25. Greco SJ, Rameshwar P. (2013) Analysis of the transfer of circulating microRNA between cells mediated by gap junction. In Circulating miRNA, Methods and Protocol Series, MolBiol (Ed. Kosaka, Nobuyoshi), Humana Press, vol 1024, p.87-96, 2013.
  26. Munoz J, Greco SJ, Rameshwar P. MicroRNA in the pathophysiology of glioblastoma.In Tumors of the central nervous system. (Ed. MA Hyat), Springer, DOI 10.1007/978-94-007-7037-9_10, 2013.
  27. Munoz JL, Park JM, Bliss SA, Rameshwar P. Chapter 21, Cancer cell dormancy: Potential therapeutic targets to eradicate cancer cells within the niche. In Trends in stem cell proliferation and cancer research. (Eds. RR Resende& H Ulrich), p. 559-571, Springer, 2013.
  28. Lim PK, Reddy BY, Rameshwar P. Toward Personalizing Stem CellTherapeutic Potential: Challenges and Opportunities for RegenerativeMedicine. In Handbook of personized medicine in nanotechnology drug delivery and therapy. (Ed. E.S. Vizirianakis), Pan Standford Publishing Pte. Ltd, Chap. 25, p. 1247-1270, 2013.
  29. Mohan RD, Bibber B, Sinha G, Patel SA. Rameshwar P. MicroRNAs in stem cells and cancer stem cells.In MicroRNA in development and in the progression of cancer. (Eds SR Singh, P Rameshwar), Springer, Chapter 5, p.81, 2014.
  30. Nahas GR, Bibber BM, Rameshwar P. MicroRNAs in epithelial mesenchymal transition and breast cancer progression.In MicroRNA in development and in the progression of cancer. (Eds SR Singh, P Rameshwar), Springer, Chapter 6, p. 103, 2014.
  31. Greco SJ, Munoz JL, Rameshwar P. MicroRNA cancer therapeutics and the challenge of drug delivery.In MicroRNA in development and in the progression of cancer. (Eds SR Singh, P Rameshwar), Springer, Chapter 18, p. 349, 2014.

OtherArticles

Reviews:

  1. Rameshwar P, Gascón P. Hematopoietic regulation mediated by interactions among the neurokinins and cytokines. Leuk Lymphoma 28:1-10, 1998.
  2. Rameshwar P, Gascón P. Hematopoietic modulation by the tachykinins.ActaHematologica 98:59-64, 1997.
  3. Rameshwar P. Substance P: A regulatory neuropeptide for hematopoiesis and immune functions. ClinImmunolImmunopathol 85:129-33, 1997.
  4. Rameshwar P, Oh HS, Yook C, Gascon P, Chang VT. Substance P-Fibronectin-Cytokine interactions in myeloproliferative disorder with bone marrow fibrosis. ActaHematologica 109:1-10, 2003.
  5. Greco SJ, Corcoran KE, Cho KJ, Rameshwar P. Tachykinins in the emerging immune system: Relevance to bone marrow homeostasis and maintenance of hematopoietic stem cells. Frontiers in Biosci 9:1782-93, 2004.
  6. Moharita A, Harrison JS, Rameshwar P. Neurokinin receptors and subtypes as potential targets in breast cancer: Relevance to bone marrow metastasis. Drug Design Reviews 1:297-302, 2004.
  7. Kang HS, Trzaska KA, Corcoran K, Chang VT, Rameshwar P. (2004) Neurokinin Receptors: Relevance to the emerging immune system. ArchivumImmunologiaeetTherapiaeExperimentalis 52:338-47.
  8. Claps CM, Corcoran KE, Cho KJ, Rameshwar P. Stromal derived factor-1 as a beacon for stem cell homing in development and injury. Curr Neurovascular Res 4:319-29, 2005.
  9. Greco SJ, Trzaska KA, Tang K,Taborga M, RameshwarP. Current issues of neurotransmitter production in neurons derived from adult stem cells. Curr Topics in Neurochem 4:61-70, 2005.
  10. Ramkissoon SH, Patel HJ, Taborga M, Rameshwar P. G-protein coupled receptors in haematopoietic disruption. Expert Opin on Biol Therapy 6:109-20, 2006.
  11. Taborga M, Corcoran KE, Fernandes N, Ramkissoon SH, Rameshwar P. G-coupled Protein Receptors and Breast Cancer Progression: Potential Drug Targets.Mini Rev in Med Chem 7:245-51, 2007.
  12. Rameshwar P. Implication of possible therapies targeted for tachykinergic system with the biology of neurokinin receptors and emerging related proteins. Recent Patents on CNS Drug Discovery 2:79-84, 2007.
  13. Trzaska KA, Rameshwar P. Current advances in the treatment of Parkinson’s Disease with stem cells. Curr Neurovascular Res 4:99-109, 2007.
  14. Castillo M, Liu K, Bonilla L, Rameshwar P. The immune properties of Mesenchymal Stem Cells. Intl JBiomed Sci 3:100-104, 2007.
  15. Murthy RG, Reddy BY, Ruggiero JE, Rameshwar P. Tachykinins and hematopoietic stem cell functions: implications in clinical disorders and tissue regeneration.Front Biosci 12:4779-87, 2007.
  16. Liu K, Castillo DM, Murthy RG, Patel N, Rameshwar P. Tachykinins and Hematopoiesis. ClinicaChimicaActa 385:28-34, 2007.
  17. Reddy BY, Trzaska KA, Murthy RG, Navarro P, Rameshwar P. (2008) Neurokinin receptors as potential targets in breast cancer treatment. Curr Drug DiscovTechnol 5:15-19.
  18. Patel SA, Sherman L, Munoz J, Rameshwar P. Immunological Properties of Mesenchymal stem cells and clinical implications.ArchivumImmunologiaeetTherapiaeExperimentalis 56:1-8, 2008.
  19. Trzaska KA, Castillo MD, Rameshwar P. Adult mesenchymal stem cells in neural regeneration and repair: current advances and future prospects. Mol Med Reports 1:307-316, 2008.
  20. Greco SJ, Rameshwar P. Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies. Biologics 2:699-705, 2008.
  21. Patel S, Heinrich A, Reddy B, Srinivas B, Heidaran N, Rameshwar P. The Multifaceted Roles of Stem cells in breast cancer biology. J Oncol2008: 425895, 2008.
  22. Heinrich AC, Patel SA, Reddy BY, Milton R, Rameshwar P. Multi- and Inter-disciplinary science in personalized delivery of stem cells for tissue repair. Current Stem Cell ResTher 4:16-22, 2009.
  23. Patel SA, Heinrich AC, Reddy BY, Rameshwar P. Inflammatory mediators: Parallels between cancer biology and stem cell therapy. J Inflammation 2:13-19, 2009.
  24. Rameshwar P. Potential novel targets in breast cancer. Curr Pharmaceutical Biotechnol10:148-53, 2009.
  25. Greco SJ, Rameshwar P. Recent Advances and Novel Approaches in Deriving Neurons from Stem Cells.Molecular BioSystems 6:324-328, 2010.
  26. Rameshwar P, Qiu H, Vatner SF. Stem cells in cardiac repair in an inflammatory microenvironment. MinervaCardioangiologica 58:127-146, 2010.
  27. Patel SA, Ndabahaliye A, Lim PK, Milton R, Rameshwar P. Challenges in the development of future treatments for breast cancer stem cells. Breast Cancer 2:1-11, 2010.
  28. Patel SA, King CC, Lim PK, Habiba U, Dave M, Porecha R, Rameshwar P. Personalizing Stem Cell Research and Therapy: The Arduous Road Ahead or Missed Opportunity?Curr Pharmacogenomics and Personalized Med 8:25-36, 2010.
  29. Gregory LA, Ricart RA, Patel SA, Lim PK, Rameshwar P. MicroRNAs, Gap Junctional Intercellular Communication and Mesenchymal Stem Cells in Breast Cancer Metastasis.Current Cancer Therapy Review 7:176-183, 2010.
  30. Klassert TE, Patel SA, Rameshwar P. Tachykinins and neurokinin receptors in bone marrow functions: neural-hematopoietic link. J Receptor, Ligand and Channel Res 3:51-61, 2010.
  31. Lim PK, Patel SA, Gregory LA, Rameshwar P. Neurogenesis: Role for microRNAs and Mesenchymal Stem Cells in Pathological States. Curr Med Chem 17:2159-67, 2010.
  32. Helmy KY, Patel SA, Silverio K, Pliner L, Rameshwar P. Stem cells and regenerative medicine: accomplishments to date and future promise. Therapeutic Delivery1:693-705, 2010.
  33. Patel SA, Dave MA, Murthy RG, Helmy KY, Rameshwar P. Metastatic breast cancer cells in the bone marrow microenvironment: novel insights into oncoprotection. Oncol Rev5:93-102, 2011.
  34. Sherman LS, Munoz JL, Patel SA, Dave MA, Paige I, Rameshwar P. Movingfrom the laboratory bench to patients’ bedside: Considerations for effective therapy with stem cells. Clin Trans Sci 4:380-6, 2011.
  35. Patel SA, Rameshwar P. Stem Cell Transplantation for Hematological Malignancies: Prospects for Personalized Medicine and Co-therapy with Mesenchymal Stem Cells. Curr Pharmacogenomics PersonMed 9:229-239, 2011.
  36. Patel SA, Rameshwar P. Exploring a stem cell basis to identify novel treatment for human malignancies. J Stem Cells 6:233-243, 2011.
  37. Reddy B, Lim P, Silverio K, Patel S, Wong BW, Rameshwar P. The microenvironmental effect in the progression, metastasis and dormancy of breast cancer within bone marrow. Intl JBreast Cancer 2012:721659, 2012.
  38. Rameshwar P.The Tachykinergic System as Avenues for Drug Intervention. Recent Patents on CNS Drug Discov 1:173-180, 2012.
  39. Greco SG, Rameshwar P. Mesenchymal stem cells in drug/gene delivery: implications for cell therapy. Ther Delivery 3: 997-1004, 2012.
  40. Nahas GR, Patel SA, Bliss SA, Rameshwar P. Can breast cancer stem cells evade the immune system? Curr Med Chem 19:6036-6049, 2012.
  41. Helmy KY, Patel SA, Nahas GR, Rameshwar P. Cancer immunotherapy:  accomplishments to date and future promise. Ther Delivery4:1307-1320, 2013.
  42. Bibber B, Sinha G, Lobba ARM, Greco S, Rameshwar P. A review of stem cell translation and potential confounds by cancer stem cells. Stem Cell Int’l2013:241048, 2013.
  43. Aleynik A, Gernavage KM, Mourad YSH, Sherman LS, Liu K, Gubenko YA, Rameshwar P. Stem cell delivery of therapies for brain disorders. ClinTransl Med3:24, 2014.
  44. Nahas G, Bliss SA, Sinha G, Ganta T, Greco SJ, Rameshwar P. Is reduction of tumor burden sufficient for the 21st century? Cancer Lett 356:149-155, 2015.

 

Pranela Rameshwar

Professor

 

  • : (973) 972 0625

  • DEPARTMENTDepartment of Medicine - Hematology/ Oncology
    Rutgers-New Jersey Medical School
  • COUNTRY USA