Publications

  1. Agadi S, Shetty AK: Prospects of Bone Marrow Mononuclear Cells and Mesenchymal Stem  Cells for Treating Status Epilepticus and Chronic Epilepsy. Stem Cells, in press, 2015.
  2. Kodali M, Parihar V, Hattiangady B, Mishra V, Shuai B, Shetty AK: Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Scientific Reports (Nature Publishing Group), 5:8075; Jan 28, 2015.
  3. Megahed T, Hattiangady B, Shuai B, Shetty AK: Parvalbumin and neuropeptide Y expressing hippocampal GABA-ergic interneuron numbers decline in a model of Gulf war illness. Frontiers in Cellular Neuroscience, 8:447, Jan 8, 2015.
  4. Shetty AK: Adult neural stem cells and brain homeostasis. Chapter for the book, Homeostatic Control of Brain Function (D. Boison and S. Masino, Eds), Oxford University Press, in press, 2015.
  5. Shetty AK, Hattiangady B: Neural stem cell therapy for easing status epilepticus induced hippocampus dysfunction and chronic temporal lobe epilepsy. Chapter for the book, Neural Stem Cells in Health and Disease (A.K. Shetty, Ed), World Scientific Press, in press, 2015.
  6. Shetty AK, Jin K: Neural stem cell activity and neurogenesis after stroke. Chapter for the book, Neural Stem Cells in Health and Disease (A.K. Shetty, Ed), World Scientific Press, in press, 2015.
  7. Shetty AK, Mishra V, Kodali M, Hattiangady B: Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves. Frontiers in Cellular Neuroscience, 8:232, Aug 13, 2014.
  8. Hattiangady B, Mishra V, Kodali M, Shuai B, Rao, X, Shetty AK: Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness. Frontiers in Behavioral Neuroscience, 8:78, March 13, 2014.
  9. Shetty AK: Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: Can early neural stem cell grafting intervention provide protection? Epilepsy & Behavior, 38:117-2, 2014.

2012-2013

  1. Parihar VK, Hattiangady B, Shuai B, Shetty AK: Mood and memory deficits in a model of Gulf war illness are linked with reduced neurogenesis, partial neuron loss and mild inflammation in the hippocampus. Neuropsychopharmacology, 38: 2348-2362, 2013.
  2. Watanabe J. Shetty AK, Hattiangady B, Kim D-K, Foraker JE, Nishida H, Prockop DJ: Administration of TSG-6 improves memory after traumatic brain injury in mice. Neurobiology of Disease, 59:86-99, 2013.
  3. Shetty AK, Hattiangady B: Postnatal age governs the extent of differentiation of hippocampal CA1 and CA3 subfield neural stem/progenitor cells into neurons and oligodendrocytes. International Journal of Developmental Neuroscience, 31: 646-656, 2013.
  4. Shetty GA, Hattiangady B, Shetty AK: Neural stem cell- and neurogenesis-related gene expression profiles in the young and aged dentate gyrus.AGE,35: 2165-2176, 2013.
  5. Shetty AK: Prospects of Levetiracetam as a neuroprotective drug against status epilepticus, traumatic brain injury and stroke. Frontiers in Neurology, 4:172, 2013. Review
  6. Hattiangady B, Shetty AK: Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory and neurogenesis. Stem Cells Translational Medicine, 1:696-708, 2012*.
    *Selected as "Featured research article" in the September issue of "Stem Cells Translational Medicine". The editorial office gave "Press Release" on this research article entitled, "Stem Cell Graft Restores Memory and Mood
  7. Shetty AK, Hattiangady B, Rao MS, Shuai B: Neurogenesis response of middle-aged hippocampus to acute seizure activity. PLoS One, PLoS One, 7(8):e43286, 2012.
  8. Shetty AK: Neural stem cell therapy for temporal lobe epilepsy, In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.

2010-2011

  1. Parihar VK, Hattiangady B, Kuruba R, Shuai B, Shetty AK: Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory. Molecular Psychiatry, 16, 171-183, 2011.
  2. Hattiangady B, Shetty AK: Neural stem cell grafting in an animal model of chronic temporal lobe epilepsy. Current Protocols in Stem Cell Biology, Chapter 2, Unit2D.7, 2011.
  3. Hattiangady B, Kuruba R, Shetty AK: Acute seizures in old age leads to a greater Loss of CA1 pyramidal neurons, an increased propensity for developing chronic TLE and a severe cognitive dysfunction, Aging and Disease, 2:1-17, 2011.
  4. Kuruba R, Hattiangady B, Parihar VK, Shuai B, Shetty AK: Differential susceptibility of interneurons expressing neuropeptide y or parvalbumin in the aged hippocampus to acute seizure activity., PLoS ONE, 6 (9), e24493, 2011.
  5. Shetty AK, Hattiangady B, Rao MS, Shuai B: Deafferentation enhances neurogenesis in the young and middle-aged hippocampus but not in the aged hippocampus. Hippocampus, 21 (6), 631-46, 2011.
  6. Shetty AK: Progress in Cell Grafting Therapy for Temporal Lobe Epilepsy. Neurotherapeutics, 8(4): 721-735, 2011.
  7. Shetty AK: Promise of resveratrol for easing status epilepticus and epilepsy. Pharmacology & Therapeutics, 131 (3), 269-86, 2011.
  8. Waldau B, Hattiangady B, Kuruba R, Shetty AK: Medial ganglionic eminence-derived neural stem cell grafts ease spontaneous seizures and restore GDNF expression in a rat model of chronic temporal lobe epilepsy. Stem Cells, 28, 1153-1164, 2010.
  9. Hattiangady B, Shetty AK: Decreased neuronal differentiation of newly generated cells underlies diminished neurogenesis in chronic temporal lobe epilepsy. Hippocampus, 20:97-112, 2010.
  10. Shetty AK: Neural stem cell therapy for temporal lobe epilepsy, Epilepsia, 51 (s5): 92-92, 2010.
  11. Shetty AK: Issues to ponder when correlating hippocampal neurogenesis with hippocampal-dependent memory function, Neurobiology of Aging, 31:2181-2184, 2010.
  12. Shetty AK: Reelin signaling, hippocampal neurogenesis, and efficacy of aspirin intake & stem cell transplantation in aging and Alzheimer's disease, Aging and Disease, 1, 2-11, 2010.
  13. Hattiangady B, Kuruba R, Shetty, AK. Effects of epileptic seizures on hippocampal neurogenesis, Chapter 14, in: Adult Neurogenesis and Central Nervous System Diseases, 2010
  14. Jin K, Shetty AK, Greenberg D. Aging & Disease, a bridge between aging and age-related disease. Aging & Disease, 1:1, 2010.

2008-2009

  1. Shetty AK, Hattiangady B, Rao MS:Vulnerability of hippocampal GABA-ergic interneurons to kainate induced excitotoxic injury during old age. Journal of Cellular & Molecular Medicine, 13(8B):2408-2423, 2009.
  2. R. Kuruba, Hattiangady B, Shetty AK. Hippocampal neurogenesis and neural stem cells in chronic temporal lobe epilepsy Epilepsy & Behavior, 14 Suppl 1:65-73, 2009.
  3. Hattiangady B, Rao MS, Shetty AK: Grafting of Striatal Precursor Cells into Hippocampus Shortly after Status Epilepticus Restrains Chronic Temporal Lobe Epilepsy. Experimental Neurology.212:468-481, 2008.
  4. Shetty AK, Rao MS, Hattiangady B:Behavior of Hippocampal Stem/Progenitor Cells Following Grafting into the Injured Aged Hippocampus. Journal of Neuroscience Research, 2008 86(14):3062-74.
  5. Rao MS, Hattiangady B, Shetty AK: Status Epilepticus during old age is not associated with increased hippocampal neurogenesis. Hippocampus, 18:931-44, 2008.
  6. Hattiangady B, Rao MS, Shetty AK:Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to injury is lost by middle age, Aging Cell, 7:207-224. 2008.
  7. Hattiangady B, Shetty AK: Aging Does not Alter the Number or Phenotype of Putative Stem/Progenitor Cells in the Neurogenic Region of the Hippocampus. Neurobiology of Aging, 29(1):129-47, 2008
  8. Waldau B, Shetty AK Behavior of Neural Stem Cells in the Alzheimer's Brain, Cellular and Molecular Life Sciences, 65:2372-84, 2008.
  9. Acharya M, Hattiangady B, Shetty AK. Progress in neuroprotective strategies for preventing epilepsy. Progress in Neurobiology, 84:363-404. 2008.
  10. Dhanushkodi A, Shetty AK. Is exposure to enriched environment beneficial for functional post-lesional recovery in TLE?Neuroscience and Biobehavioral Reviews,32:657-674, 2008.
  11. Hattiangady B., Shetty AK. Implications of declined hippocampal neurogenesis in chronic temporal lobe epilepsy EPILEPSIA,2008, 49 (s5) 26-41.

2006-2007

  1. Shetty AK, Hattiangady B: Restoration of calbindin after fetal hippocampal CA3 cell grafting into the injured hippocampus in a rat model of temporal lobe epilepsy. Hippocampus, 17(10): 943-956, 2007.
  2. Rai K, Hattiangady B, Shetty AK: Enhanced production and dendritic growth of new dentate granule cells in the middle-aged hippocampus following intracerebroventricular FGF-2 infusions. Eur J Neurosci, 26:1765-1779, 2007.
  3. Rao MS, Hattiangady B, Rai KS, Shetty AK:Strategies for enhanced survival and anti-epileptogenic effects of hippocampal fetal cell grafts in the hippocampus of rats exhibiting chronic temporal lobe epilepsy. Neurobiology of Disease, 27:117-132, 2007.
  4. Hattiangady B, Shuai B, Cai J, Coksaygan T, Rao MS, Shetty AK: Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus STEM CELLS, 25:2104-2117, 2007.
  5. Shetty AK and Hattiangady B. Prospects of Stem Cell therapy for Temporal Lobe Epilepsy.Stem Cells, 25:2396-2407, 2007.
  6. R. Kuruba, Shetty AK. Could hippocampal neurogenesis be a future drug target for treating temporal lobe epilepsy? CNS and Neurodegenerative Disorders-Drug Targets, 6(5): 342-57, 2007.
  7. Rao MS, Hattiangady B, Shetty AK: The window and mechanisms of major age related decline in the production of new neurons within the dentate gyrus of the hippocampus. Aging Cell, 5:545-558, 2006.
  8. Hattiangady B, Rao MS, Zaman V, Shetty AK: Incorporation of embryonic CA3 cell grafts into the adult hippocampus at 4-months after injury: effects of combined neurotrophic supplementation and caspase inhibition. Neuroscience, 139:1369-1383, 2006.
  9. Rao, MS, Hattiangady B, Reddy DS, Shetty AK: Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy. Journal of Neuroscience Research, 83:1088-1105, 2006.
  10. Rao, MS, Hattiangady B, Shetty AK: Fetal hippocampal CA3 cell grafts enriched with FGF-2 and BDNF exhibit robust long-term survival and integration and suppress aberrant mossy fiber sprouting in the injured middle-aged hippocampus. Neurobiology of Disease, 21:276-290, 2006.

2004-2005

  1. Shetty AK, Zaman V, Hattiangady B: Repair of the injured adult hippocampus through graft-mediated modulation of the plasticity of the dentate gyrus in a rat model of temporal lobe epilepsy. Journal of Neuroscience, 25: 8391-8401, 2005.
  2. Shetty AK, Hattiangady B, Shetty GA: Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes, GLIA, 51:173-186, 2005.
  3. Hattiangady B, Rao MS, Shetty GA, Shetty AK: BDNF, p-CREB and NPY decline as early as middle age in the dentate gyrus and hippocampal CA1 and CA3 subfields. Experimental Neurology, 195:353-371. 2005.
  4. He J, Nixon K, Shetty AK, Crews FT: Chronic alcohol exposure reduces hippocampal neurogenesis and dendritic growth of newborn neurons. European Journal of Neuroscience, 21:2711-2720, 2005.
  5. Rao MS, Hattiangady B, Abdel-Rahman A, Stanley D, Shetty AK: Newly born cells in the aging dentate gyrus display normal migration, survival and neuronal fate-choice but endure retarded early maturation. European Journal of Neuroscience, 21: 464-476. 2005.
  6. Hattiangady B, Rao MS, Shetty AK. Chronic temporal lobe epilepsy severely diminishes dentate neurogenesis in the adult hippocampus.  Neurobiology of Disease, 17: 473-490, 2004.
  7. Shetty AK, Rao MS, Hattiangady B, Zaman V, Shetty GA:Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury. Journal of Neuroscience Research, 78:520-532, 2004.
  8. Shetty AK:  Progenitor cells from the CA3 region of the E19 rat hippocampus generate region-specific neuronal phenotypes in vitro. Hippocampus, 14: 595-614, 2004.
  9. Rao MS,Shetty AK: Efficacy of doublecortin as a marker to analyze the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur. Journal of Neuroscience, 19: 234-246, 2004.
  10. Stanley DP, Shetty AK: Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration. Journal of Neurochemistry, 89: 204-216, 2004.
  11. Abdel-Rahman, A, Rao MS, Shetty AK: Aging impairs the response of astrocytes to neurodegeneration and deafferentation in the hippocampus. GLIA, 47: 299-313, 2004.
  12. Safford KM, Safford SD, Gimble JM, Shetty, AK, Rice HE: Characterization of neuronal/glial differentiation of murine adult adipose-derived stromal cells. Experimental Neurology, 187:319-328,2004.
  13. Abdel-Rahman A, Abou-Donia S, El-Masry E, Shetty AK, Abou-Donia M: Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produces neurochemical and neuropathological alterations in cerebral cortex, hippocampus and cerebellum. J Toxicol Environ Health A, 67:163-192, 2004.
  14. Pradhan A, Shetty AK, Turner, DA: Clinical prospects for neural grafting therapy for cortical lesions. Modern Neurosurgery (Editor: Turner DA), CRC Press, pp. 17-36, 2004.
  15. Shetty AK: Editorial: Stem cells and Aging. Aging Cell, 3:331-331, 2004.

2002-2003

  1. Shetty AK, Zaman V, Shetty G: Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between BDNF content and progression of aberrant dentate mossy fiber sprouting.  Journal of Neurochemistry, 87: 147-159, 2003.
  2. Zaman V, Shetty AK:  Pre-treatment of donor cells with FGF-2 enhances survival of fetal hippocampal CA3 cell transplants in the chronically lesioned young adult hippocampus. Experimental Neurology, 183: 11-24, 2003. Cover article
  3. Zaman, V, Shetty AK: Fetal hippocampal CA3 cell grafts enriched with FGF-2 exhibit enhanced neuronal integration into the lesioned aging hippocampus in a rat model of temporal lobe epilepsy. Hippocampus, 13: 618-632, 2003.
  4. Guo-Ross SX, Jones KH, Shetty AK, Wilson WA, Swartzwelder HS. Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat. Neuroscience Letters, 341:161-163, 2003.
  5. Turner, DA, Shetty AK: Clinical Prospects for Neural Grafting Therapy for Hippocampal Lesions and Epilepsy. Neurosurgery, 52: 632-644, 2003. Review,
  6. Zaman, V, Shetty AK: Survival of fetal hippocampal CA3 cell grafts in the middle aged and aged hippocampus: Effect of host age and deafferentation. Journal of Neuroscience Research, 70: 190-199, 2002.
  7. Shetty AK:  Entorhinal axons exhibit aberrant sprouting in CA1 subfield of the adult hippocampus after CA3-lesion. Hippocampus, 12: 534-542, 2002.
  8. Zaman, V, Shetty AK: Combined neurotrophic supplementation and caspase inhibition significantly enhances survival of fetal hippocampal CA3 cell grafts in kainic acid lesioned CA3 region of the aging hippocampus. Neuroscience, 109: 537-553,2002.
  9. Guo-Ross, SX, Clark S, Montoya DAC, Jones KH, Obernier J, Shetty AK, White AM, Blusztajn JK, Wilson WA, Swartzwelder HS: Prenatal Choline Supplementation Protects Against Postnatal Neurotoxicity, Journal of Neuroscience, 22: RC195, 1-6, 2002.
  10. Abdel-Rahman, A, Shetty AK, Abou-Donia, MB: Acute exposure to sarin increases blood brain barrier permeability and induces neuropathological changes in the rat brain: dose response relationships. Neuroscience, 113: 721-741, 2002.
  11. Abdel-Rahman, A, Shetty AK, Abou-Donia, MB: Disruption of Blood Brain Barrier and Neuronal Cell Death in Cingulate Cortex, Dentate Gyrus, Thalamus, and Hypothalamus in A Rat Model of Gulf-War Syndrome. Neurobiology of Disease, 10: 306-326, 2002.

2000-2001

  1. Zaman V, Shetty AK: Fetal hippocampal CA3 cell grafts transplanted to lesioned CA3 region of adult hippocampus exhibit long-term survival in a rat model of temporal lobe epilepsy. Neurobiology of Disease, 8: 942-952, 2001.
  2. Shetty AK, Turner DA: Glutamic acid decarboxylase positive hippocampal interneurons undergo a permanent reduction in number following kainic acid induced destruction of CA3 pyramidal neurons. Experimental Neurology, 169: 276-297, 2001.
  3. Zaman V, Turner, DA, Shetty AK: Prolonged post-lesion transplantation delay adversely influences survival of both homotopic and heterotopic fetal hippocampal cell grafts in kainate-lesioned CA3 region of adult hippocampus. Cell Transplantation, 10: 41-52, 2001.
  4. Abdel-Rahman, A, Shetty AK, Abou-Donia MB: Subchronic derma application of N, N-diethyl m-toluamide (DEET) and permethrin to adult rats, alone or in combination, causes diffuse neuronal cell death and cytoskeletal abnormalities in the cerebral cortex and the hippocampus, and Purkinje neuron loss in the  cerebellum. Experimental Neurology, 172: 153-171, 2001.
  5. Shetty AKand Turner DA: Fetal hippocampal transplants containing CA3 cells restore host hippocampal interneuron numbers in a rat model of temporal lobe epilepsy. Journal of Neuroscience, 20: 8788-8801, 2000.
  6. Shetty AK, Zaman V, and Turner DA: Pattern of long-distance projections from hippocampal field CA3 and CA1 cell grafts in lesioned CA3 of adult hippocampus follows intrinsic character of respective donor cells. Neuroscience, 99: 243-255, 2000.
  7. Zaman V, Turner DA and Shetty AK: Survival of grafted fetal neural cells in kainic acid lesioned CA3 region of adult hippocampus depends upon cell specificity. Experimental Neurology, 161:535-561, 2000.

1998-1999

  1. Shetty AK and Turner DA: Aging impairs axonal sprouting response of dentate granule cells following target loss. Journal of Comparative Neurology, 414: 238-254, 1999.
  2. Shetty AK and Turner DA: Vulnerability of dentate gyrus to aging and intracerebroventricular administration of kainic acid. Experimental Neurology, 158: 491-503, 1999.
  3. Shetty AK and Turner DA: Neurite Outgrowth from progeny of Epidermal growth factor-responsive hippocampal stem cells is significantly less robust than from fetal hippocampal cells following grafting onto organotypic slice cultures: Effect of brain-derived neurotrophic factor. Journal of Neurobiology, 38:391-413, 1999, Cover article.
  4. Shetty AK and Turner DA: In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: enhancing and inducing effects of BDNF. Journal of Neurobiology, 35:395-425, 1998, Cover article
  5. Shetty AK and Turner DA: Hippocampal interneurons expressing glutamic acid decarboxylase and calcium binding proteins decrease with aging in Fischer 344 rats.  Journal of Comparative Neurology 394:252-269, 1998.

1996-1997

  1. Shetty AK and Turner DA: Fetal hippocampal cells grafted to kainate-lesioned CA3 of adult hippocampus suppress aberrant supragranular sprouting. Experimental Neurology 143:231-245, 1997.
  2. Shetty AK and Turner DA: Development of long-distance efferent projections from fetal hippocampal grafts depends upon pathway specificity and graft location in kainate-lesioned adult hippocampus. Neuroscience 76:1205-1219, 1997.
  3. Shetty AK and Turner DA: Development of fetal hippocampal grafts in intact and lesioned hippocampus. Progress in Neurobiology 50:593-653, 1996.

1994-1995

  1. Shetty AK and Turner DA: Enhanced cell survival in fetal hippocampal transplants grafted to adult rat hippocampus following kainate lesions. Neuroscience 67: 561-582,1995.
  2. Shetty AK, Rapoza D, Madison RD and Turner DA: Selective laser-activated lesioning of pre-labeled fetal hippocampal grafts by intracellular photolytic chromophore. Neuroscience69: 407-416, 1995.
  3. Shetty AK and Turner DA: Intracerebroventricular administration of kainic acid in rats causes alterations in hippocampal calbindin and non-phosphorylated neurofilament protein expression. Journal of Comparative Neurology 363: 581-599, 1995.
  4. Shetty AK and Turner DA: Non-phosphorylated neurofilament immunoreactivity in adult and developing hippocampus: application in grafting studies. Brain Research 676:293-306, 1995.
  5. Burrows RC, Shetty A Kand Phillips DE: Effect of in utero ethanol exposure on the morphological development of the oculomotor nucleus in rat. Teratology 51:318-328, 1995.
  6. Clarke SR,Shetty AK,Bradley J and Turner DA: Reactive astrocytes express the embryonic intermediate neurofilament nestin. NeuroReport, 5:1885-1888, 1994.
  7. Shetty AK, Madison RD, Bradley J and Turner DA: Quantitative graft integration of fetal hippocampal transplants labeled with 5'bromodeoxy-uridine into normal hippocampus. Experimental Neurology 126:205-224, 1994.
  8. Shetty AK, Burrows RC, Wall KA and Phillips DE: Combined pre- and post-natal ethanol exposure alters the development of Bergmann glia in rat. International Journal of Developmental Neuroscience 12:641-649, 1994.

1992-1993

  1. Shetty AK, Burrows RC and Phillips DE: Alterations in neuronal development in the substantia nigra pars compacta following in utero ethanol exposure. Neuroscience 52:311-322, 1993.
  2. Shetty AK and Phillips DE: Effects of prenatal ethanol exposure on the development of Bergmann glia and astrocytes in the cerebellum: An immunohistochemical study. Journal of Comparative Neurology 321:19-32, 1992.
  3. Tandon PN, Kumar VM, Verma S, Gopinath G and Shetty AK: Fetal brain transplants in kainic acid lesioned caudate nucleus of adult rats. Journal of Neural Transplantation and Plasticity 3:125-134, 1992.

1990-1991

  1. Shetty AK, Banerjee R, Gopinath G and Tandon PN: Fetal nigral grafts in the anterior eye chamber of adult rats: A morphological study. Experimental Neurology 111:106-114, 1991.
  2. Shetty AK, Gopinath G and Tandon PN: Fetal nigral transplants in the lateral ventricle of adult rats: A long-term morphological study. Developmental Neuroscience 13:1-10, 1991.
  3. Shetty AK, Gopinath G and Tandon PN: Adrenal medullary autografts in the anterior eye chamber, lateral ventricle and striatum of adult rats: A long-term study. Journal of Neural Transplantation and Plasticity 2:175-191, 1991.
  4. Gopinath G, Shetty AK, and Tandon PN: Ageing changes in the transplants of fetal substantia nigra grafted to striatum of adult rat. Neuroscience 40:429-443, 1991.
  5. Gopinath G, Mahapatra AK, Bharadwaj JC, Banerjee R, Shetty AK, Sharma DN and Tandon PN: MPTP model of Parkinson's disease in monkey: Implications in neural transplantation. Proceedings of Indian National Science Academy 56:95-100, 1990.Review,
  6. Tandon PN, Gopinath G, Mahapatra AK and Shetty AK: Neural transplantation in   mammals: Our experience. Proceedings of Indian National Science Academy 56:51-58, 1990. Review,
  7. Gopinath G, Shetty AK,and Tandon PN: In oculo differentiation of fetal neocortex into retina in adult rat. In: Neurobiology of Sensory System, Plenum press, NY, pp.231-239, 1988. Book Chapter.

Links To News Articles Pertaining To My Published Papers

  1. Hattiangady B, Rao MS, Shetty AK(2004). Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus. Neurobiology of Disease, 17(3):473-490.
    Chronic Epilepsy Decreases Brain Cell Production in Critical Learning and Memory Center (Link: http://www.sciencedaily.com/releases/2005/01/050111174433.htm) SCIENCE DAILY, January 15, 2005.
    Epilepsy Study Gives Insight to Mood Disorders by FOX NEWS January 5, 2005.
  2. Shetty AK, Hattiangady B, Shetty GA(2005). Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes. GLIA, 51(3):173-186.
    New clues into the Aging Brain by DUKE UNIVERSITY news office August 5, 2005.
  3. Hattiangady B, Shetty AK (2006). Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus.Neurobiology of Aging29:129-47.
    Stem Cell Activity Deciphered in the Aging Brain by DUKE UNIVERSITY news office, December 18, 2006.
    Stem Cell Activity Deciphered in the Aging Brain by SCIENCE DAILY, December 18, 2006.
    Stem Cell Loss in Aging Brain may bring Poorer Memory by WASHINGTON POST, December 22, 2006
    Old Age Memory Loss Explained by COSMOS magazine, Australia, December 20, 2006
  4. Hattiangady B, Shuai B, Cai J, Coksaygan T, Rao MS, Shetty AK: Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampusSTEM CELLS, 25:2104-2117, 2007.
    Novel way to trigger new neuron production in the aging brain by DUKEHEALTH.ORG August 2007.
  5. Hattiangady B, Kuruba R, Shetty AK: Acute seizures in old age leads to a greater Loss of CA1 pyramidal neurons, an increased propensity for developing chronic TLE and a severe cognitive dysfunction, Aging and Disease, 2:1-17, 2011.
    Outcome of acute seizures in more devastating in the aged population than in the young adults, SciGuru (http://www.sciguru.com/) Science News.
  6. Kuruba R, Hattiangady B, Parihar VK, Shuai B, Shetty AK: Differential susceptibility of interneurons expressing neuropeptide y or parvalbumin in the aged hippocampus to acute seizure activity., PLoS ONE, 6 (9), e24493, 2011.
    Increased Vulnerability for Developing Temporal Lobe Epilepsy after Acute Seizure Activity in Old Age Explained, SciGuru (http://www.sciguru.com/) Science News.
  7. Hattiangady B, Shetty AK: Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory and neurogenesis. Stem Cells Translational Medicine, 1:696-708, 2012.
    Hippocampal Stem Cell Grafts Reportedly Improve Mood and Memory in Rats - in Neurology Today (October 2012); Stem Cell Therapy for Mood and Memory in STEM CELLS PORTAL (September 2012)
  8. Kodali M, Parihar V, Hattiangady B, Mishra V, Shuai B, Shetty AK: Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Scientific Reports (Nature Publishing Group), 5:8075; Jan 28, 2015.http://www.nature.com/srep/2015/150128/srep08075/full/srep08075.html
    Compound found in grapes, red wine may help prevent memory loss  vital RECORD (Texas A&M HSC News), January 2015

SELECTED S Of Presentations At International Scientific Meetings:

2014-2015

  1. Shetty GA, Hattiangady B, Shuai B, Shetty AK. Long-standing effects of exposure to gulf war illness related chemicals and mild stress on the expression of genes encoding oxidative stress and inflammation in the hippocampus. Society for Neuroscience Meeting s, 496.17, 2014, Washington DC.
  2. Hattiangady B, Shuai B, Shetty GA, Mishra V, Kodali M, Rao X, Shetty AK.Promise of resveratrol for relieving cognitive and mood dysfunction, hippocampus oxidative stress and inflammation in gulf war illness. Society for Neuroscience Meeting s, 496.09, 2014, Washington DC.
  3. Shetty AK, Mishra V, Hattiangady B, Robbins AB, Moreno MR, Prockop DJ, Jones R, Obenaus A, Shuai B, Kodali M, Rao X. Shock waves of a single blast can cause longstanding impairments in pattern separation and other cognitive function, mood and hippocampus neurogenesis, and white matter injury. Society for Neuroscience Meeting s, 522.24, 2014, Washington DC.
  4. Mishra V, Hattiangady B, Robbins AB, Shuai B, Moreno MR, Prockop DJ, Shetty AK (2014): Mild traumatic brain injury induced through an exposure to blast shock waves causes lasting hippocampus-dependent and hippocampus-independent memory dysfunction and depression. Cell Transplantation, 23 (6): 778-778, 2014.
  5. Kodali M, Hattiangady B, Watanabe J, Rao X, Shetty AK (2014): Unilateral moderate controlled cortical impact traumatic brain injury induces enduring deficits in spatial, object location, object recognition and pattern separation memory and mood function. Cell Transplantation, 23 (6): 774-775, 2014.
  6. Shetty AK, Hattiangady B, Shetty G, Mishra V, Choi H, Yu JM, Prockop DJ, Kodali M, Shuai B, Rao X (2014):Intraperitoneal Administration of Human Mesenchymal Stem Cells Restrains Status Epilepticus Induced Neurodegeneration and Inflammatory Reaction in the Hippocampus. Annual Meeting of the International Society for Stem Cell Research (ISSCR), Vancouver, Canada.

2012-2013

  1. Hattiangady B, Liu Y, Shuai B, Yao L, Rao X,  Zhang S.-C, Shetty AK(2013): Survival, differentiation and functional effects of human iPSC-derived MGE progenitor cells in a model of temporal lobe epilepsy. Society for Neuroscience meeting s, San Diego, USA. 414.18.
  2. Mishra V, Shuai B, Hattiangady B, Shetty AK (2013): Resveratrol treatment after the onset of status epilepticus reduces neurodegeneration and inflammation in the adult hippocampus. Society for Neuroscience meeting s, San Diego, USA. 534.15.
  3. Shetty AK, Parihar VK, Hattiangady B, Shuai B, Rao X (2013): Fluoxetine treatment improves hippocampal neurogenesis and eases cognitive and mood dysfunction in a model of gulf war illness. Society for Neuroscience meeting s, San Diego, USA. 608.01.
  4. Shetty G, Hattiangady B, Shuai B, Shetty AK (2013): Oral treatment of resveratrol to aged rats enhances the expression of pro-cognitive and anti-inflammatory genes in the hippocampus and eases cognitive dysfunction. Society for Neuroscience meeting s, San Diego, USA. 608.05.
  5. Kodali M, Parihar V, Hattiangady B, Shuai B, Shetty AK (2013): Intraperitoneal resveratrol treatment alleviates age-related impairments in spatial memory, mood and hippocampal neurogenesis. Society for Neuroscience meeting s, San Diego, USA. 608.07.
  6. Shetty AK, Hattiangady B, Shuai B, Rao X (2013) Resveratrol treatment in old age enhances the activity of stem cells in the hippocampus and maintains normal cognitive function. Annual Meeting of the International Society for Stem Cell Research (ISSCR), Boston, USA.
  7. Hattiangady B, Kuruba R, Shuai B, Waldau B, Shetty AK (2012) Neural stem cell grafting after status epilepticus restrains spontaneous recurrent seizures and preserves cognitive and mood function.Society for Neuroscience meeting s, New Orleans, USA.
  8. Shetty AK, Hattiangady B, Shuai B, Rao, X (2012) Resveratrol enhances neurogenesis in the aged hippocampus. Society for Neuroscience meeting s, New Orleans, USA.
  9. Shetty G, Hattiangady B, Shuai B, Shetty AK (2012) Hippocampal neurogenesis related gene expression and cognitive function in young and aged rats after a unilateral hippocampal injury. Society for Neuroscience meeting s, New Orleans, USA.
  10. Shetty AK, Hattiangady B (2012) Neural stem cell grafting counteracts hippocampal-injury mediated impairments in mood, memory and neurogenesis. Annual Meeting of the International Society for Stem Cell Research (ISSCR), Yokohama.
  11. Hattiangady B, Kuruba R, Shuai B, Waldau B, Shetty AK (2012) Efficacy of intra-hippocampal grafting of subventricular zone derived neural stem cells for easing status epilepticus induced temporal lobe epilepsy and related co-morbidities.American Society for Neural Therapy & Repair Meeting, Clearwater Beach, FL.

2010-2011

  1. Hattiangady B, Shetty AK(2011). Subventricular zone derived neural stem cell grafts ease partial hippocampal injury induced impairments in memory, mood and neurogenesis. Soc. Neurosci. s, 30.07.Washington DC, USA.
  2. Hattinagady B, Shuai B, Parihar V, Shetty AK (2011). Medial ganglionic eminence precursor cell grafting diminishes spontaneous seizures and improves memory function in a rat model of temporal lobe epilepsy. 11th International Neural Transplantation and Repair meeting, Clear Water Beach, FL.
  3. Grier R, Hattiangady B, Kuruba R, Parihar VK, Shuai B, Shetty AK(2010). Extent of preservation of hippocampal Reelin+ interneurons predicts the ability for spatial learning & memory function in chronic temporal lobe epilepsy. Soc. Neurosci. s, 202.29. San Diego, USA.
  4. Shetty AK, Parihar VK, Hattiangady B, Babb E, Shuai B (2010). Neural stem cell dysfunction and its implications on memory & mood functions in a rat model of Gulf War illness. Soc. Neurosci. s, 29.17. San Diego, USA.
  5. Hattiangady B, Kuruba R, Parihar VK, Shetty AK (2010). Intrahippocampal grafting of NSCs after status epilepticus eases both spontaneous seizures & cognitive dysfunction in a rat model of temporal lobe epilepsy. Soc. Neurosci. s, 29.30. San Diego, USA.
  6. Parihar VK and Shetty AK (2010). Rolipram treatment alleviates learning, memory & mood dysfunction with enhanced hippocampal neurogenesis in a rat model of Gulf War Illness. Soc. Neurosci. s, 29.10. San Diego, USA.
  7. B. Shuai, B. Hattiangady, R. Grier, Shetty AK (2010). Early FGF-2 treatment greatly restrains status epilepticus induced spontaneous seizures, cognitive dysfunction and depression in aged rats. Soc. Neurosci. s,812.13. San Diego, USA.
  8. Grier R, Hattiangady B, Kuruba R, Parihar VK, Shetty AK (2010) Relationship between the survival of Reelin+ interneurons and cognitive function in a rat model of temporal lobe epilepsy. Annual meeting of the American Society for Neural Therapy and Repair, Florida, USA.
  9. Parihar VK, Hattiangady B, Bing Shuai, Shetty AK (2010). Exposure to Gulf war illness related chemicals induces cognitive dysfunction, depression and impaired hippocampal neurogenesis. Annual meeting of the American Society for Neural Therapy and Repair, Florida, USA.

2008-2009

  1. Shetty AK Parihar VK, Hattiangady B, Kuruba R, Shuai B (2009). Predictable chronic mild stress increases hippocampal neurogenesis and diminishes depressive and anxiety like behaviors. Soc. Neurosci. s.
  2. Parihar VK, Hattiangady B, Shuai B, Shetty AK(2009).Hippocampal neurogenesis is impaired in a rat model of Gulf War Syndrome.Soc. Neurosci. s, Chicago, IL, USA.
  3. Hattiangady B, Shuai B, Shetty AK (2009). FGF-2 administration shortly after the onset of status epilepticus provides hippocampal neuroprotection and diminishes depressive-like behavior in aged rats. Soc. Neurosci. s, Chicago, IL, USA.
  4. Kuruba R, Hattiangady B, Shetty AK (2009). Transplantation of hippocampal stem cells shortly after status epilepticus diminishes chronic epilepsy development. Annual meeting of the American Society for Neural Therapy & Repair, Clear Water Beach, FL, USA.
  5. Parihar VK, Shuai B, Hattiangady B, Shetty AK (2009). Predictable chronic mild stress enhances hippocampal neurogenesis in the adult brain. Annual meeting of the American Society for Neural Therapy & Repair, Clear Water Beach, FL, USA.
  6. Shetty AK Hattiangady B (2009). Aging does not impair the survival and differentiation of grafted stem cells from the anterior subventricular zone. Regulatory Networks of Stem Cells Conference, Singapore.
  7. Shetty AK, Hattiangady B, Rao MS (2009):Susceptibility of hippocampal GABA-ergic interneurons to excitotoxic injury in old age. American Society of Neurochemistry meeting, Charleston, SC, USA.
  8. Shetty AK Hattiangady B (2008). Integration of stem cells from the anterior subventricular zone after grafting into the intact or lesioned young hippocampus. Annual meeting of International Society for Stem Cell Research, Philadelphia, USA.
  9. Shetty AK, Rao MS, Hattiangady B (2008) Deafferentation increased neurogenesis in the young and middle-aged hippocampus but not in the aged hippocampus. Soc. Neurosci. s, Washington DC, USA.
  10. Hattiangady B, Kuruba R, Rao MS, Reddy DS, Zheng B, Shuai B, Shetty AK (2008) Grafting of hippocampal precursors shortly after status epilepticus considerably reduces spontaneous recurrent motor seizures during the chronic phase of epilepsy. Soc. Neurosci. s, Washington DC, USA.
  11. Kuruba R, Hattiangady B, Rao MS, Shetty AK (2008). Early grafting of hippocampal precursors reduces status epilepticus induced learning and memory impairments in a rat model of temporal lobe epilepsy. Soc. Neurosci. s, Washington DC, USA.
  12. Waldau B, Kuruba R, Hattiangady B, Shetty AK (2008). Grafting of neural stem cells isolated from the embryonic medial ganglionic eminence diminishes spontaneous seizures in a rat model of chronic temporal lobe epilepsy. Soc. Neurosci. s, Washington DC, USA.
  13. Shuai B., Kuruba R, Hattiangady B, Shetty AK (2008). Susceptibility of the aged hippocampus to kainate induced status epilepticus. Soc. Neurosci. s, Washington DC, USA.

2006-2007

  1. Hattiangady B, Rao MS, Rai KS, Shetty AK (2007). Efficacy of striatal precursor cell grafting into the hippocampus for suppressing the progression of status epilepticus into chronic epilepsy, Annual meeting of the American Society for Neural Therapy and Repair, Florida, USA.
  2. Hattiangady B and Shetty AK (2007). Subcutaneous Administration of BDNF Dramatically Enhances Dentate neurogenesis in the Injured Aged hippocampus Soc. Neurosci. s, San Diego, USA.
  3. Acharya MM, Rai K, Hattiangady B, Shetty AK (2007). Potential of hippocampal stem/progenitor cell grafts for restraining spontaneous motor seizures during chronic temporal lobe epilepsy. Soc. Neurosci. s, San Diego, USA.
  4. Shetty AK Hattiangady B (2007). Behavior of stem cells from the anterior subventricular zone after grafting into the young and aged hippocampus. Soc. Neurosci. s, San Diego, USA.
  5. Kuruba R, Hattiangady B, Acharya MM, Shetty AK (2007). Hippocampal stem cell activity in a rat model of chronic temporal lobe epilepsy. Soc. Neurosci. s, San Diego, USA.
  6. Hattiangady B, Rao MS, Zeng YC, Reddy DS, Shetty AK (2006). Lasting inhibition of spontaneous recurrent motor seizures after hippocampal precursor cell grafting in rats exhibiting chronic temporal lobe epilepsy. Soc. Neurosci. s, Atlanta, USA.
  7. Shuai B, Hattiangady B, Cai J, Coksaygan T, Rao MS, Shetty AK (2006). Enhanced dentate neurogenesis in the aging hippocampus following grafting of sox-2+ neural stem cells. Soc. Neurosci. Abstr.
  8. Rai KS, Hattiangady B, Shetty AK (2006). Two-week infusions of FGF-2 into the lateral ventricle greatly increase the production Soc. Neurosci and growth of new dentate granule cells in the aging hippocampus. Soc. Neurosci. s, Atlanta, USA.
  9. Shetty AK, Hattiangady B (2006). Survival and differentiation of stem/progenitor cells from the postnatal hippocampus following grafting into the intact or injured young adult and aged hippocampus. Soc. Neurosci. s, Atlanta, USA.
  10. Reddy DS, Zeng Y, Hattiangady B, Shetty AK (2006). Diminished spontaneous recurrent seizure activity after GABA-ergic neurosteroid therapy in the pilocarpine model of chronic epilepsy. Soc. Neurosci. s, Atlanta, USA.
  11. Hattiangady B, Cai J, Coksaygan T, Rao MS, Shetty AK (2006) Transplants of glial restricted progenitors stimulate the proliferation of stem/progenitor cells and increase the production of new dentate granule cells in the aging hippocampus. International Society for Stem Cell Research meeting, Toronto, Canada.
  12. Rai KS, Hattiangady B, Rao MS, Shetty AK (2006). Long-term survival and phenotypic differentiation of neural stem/progenitor cell transplants in the injured hippocampus of chronically epileptic rats. Annual meeting of International Society for Stem Cell Research, Toronto, Canada.

2004-2005

  1. Hattiangady B, Shetty AK (2005). Intracerebroventricular infusions of Fgf-2 or BDNF enhance dentate neurogenesis in the injured senescent hippocampus.Soc. Neurosci. s, Washington DC, USA.
  2. Rao MS, Hattiangady B, Shetty AK (2005). Survival and behavioral effects of fetal hippocampal cell grafts in a rat model of chronic temporal lobe epilepsy.Soc. Neurosci. s, Washington DC, USA.
  3. Rai KS, Rao MS, Hattiangady B, Shetty AK (2005). Status epilepticus does not enhance dentate neurogenesis in the aged hippocampus. Soc. Neurosci. s, Washington DC, USA.
  4. Shetty AK, Hattiangady B (2005). Aging does not decrease the number of sox-2 (a putative neural stem/progenitor cell marker) immunopositive cells in the dentate subgranular zone. Soc. Neurosci. s, Washington DC, USA.
  5. Shuai B, Rao MS, Hattiangady B, Shetty AK (2005). The window of major decline in dentate neurogenesis during the course of aging. Soc. Neurosci. s, Washington DC, USA.
  6. Hattiangady B, Rao MS, Rai KS,Shetty AK (2005). Enduring Survival of new neurons born at early post-status and during chronic epilepsy in the rat dentate gurus. Annual Meeting of American Epilepsy Society, Washington DC, USA.
  7. Rao MS, Hattiangady B, Reddy S, Shetty AK (2005). Neurodegeneration, Spontaneous recurrent motor seizure and Mossy Fiber Sprouting   in a model of Temporal Lobe Epilepsy using F-344 rats.Annual Meeting of American Epilepsy Society, Washington DC, USA.
  8. Hattiangady B, Shetty AK (2004). Subcutaneous administration of Fibroblast Growth Factor-2 (FGF-2) enhances dentate neurogenesis in the injured aged hippocampus.Soc. Neurosci. s, San Diego, USA.
  9. Shetty AK, Hattiangady B (2004). Progenitor cells responsive to EGF/FGF-2 persist in both CA1 and CA3 regions of the postnatal rat hippocampus.Soc. Neurosci. s, San Diego, USA.
  10. Shuai B, Hattiangady B, Rao MS, Shetty AK (2004). Chronic hippocampal injury severely diminishes the addition of new neurons to the adult dentate gurus. Soc. Neurosci. s, San Diego, USA.
  11. Shetty AK, Hattiangady B, Shetty GA (2004). Stem/Progenitor cell Proliferation factors FGF-2, IGF-1 and VEGF exhibit early decline in the hippocampus during aging. Annual Meeting of American Society of Neurochemistry, New York, USA.

2002-2003

  1. Shetty, AK, Rao, MS (2003). Survival and differentiation of FGF-2 responsive hippocampal stem/progenitor cells from GFP expressing transgenic mice in the lesioned aging hippocampus. Soc. Neurosci. Abstr.
  2. Rao MS, Abdel-Rahman, A., Stanley D, Shetty, AK (2003). Production of new neurons in the middle-aged and the senescent dentate gyrus after hippocampal injury. Society for Neuroscience s.
  3. Abdel-Rahman, A., Rao MS, Stanley D, Shetty, AK (2003). Are newly generated granule cells in the lesioned adult and aged hippocampus capable of long-term survival. Soc. Neurosci. Abstr..
  4. Hattiangady B, Rao MS, Shetty, AK (2003). Long-term survival and integration of fetal hippocampal CA3 cell grafts enriched with neurotrophic factors FGF-2 and BDNF in the lesioned aging hippocampus. Society for Neuroscience s.
  5. Shetty AK, Zaman V (2002). Fetal hippocampal CA3 cell grafts enriched with FGF-2 exhibit enhanced neuronal integration into the lesioned aging hippocampus in a rat model of temporal lobe epilepsy. Society for Neuroscience s, 2002.
  6. Abdel-Rahman A, Shetty, AK (2002). Aging alters the responsiveness of hippocampal astrocytes to neurodegeneration and deafferentation. Society for Neuroscience s, 2002.
  7. Shetty AK (2002). Efficacy of Neural Transplants for Repair of the Injured Hippocampus in a Rat Model of Temporal Lobe Epilepsy, s of FIRST INDO-US SYMPOSIUM ON BRAIN RESEARCH (Sponsored by NIH-NIMH (USA) and National Brain Res. Ctr. (INDIA).

2000-2001

  1. Shetty AK (2001). Fetal hippocampal CA3 cell grafts into the lesioned adult CA3 region restore host hippocampal calbindin expression in a rat model of temporal lobe epilepsy. Soc. Neurosci. Abstr.
  2. Zaman V, Shetty AK (2001). Combined neurotrophic supplementation and caspase inhibition significantly enhances survival of fetal hippocampal CA3 cell grafts in kainic acid lesioned CA3 region of the aging hippocampus. Society for Neuroscience s.
  3. Guo-Ross, SX, Clark S, Shetty AK, Montoya DAC, Jones KH, Obernier J, White AM, Wilson WA, Swartzwelder HS (2001): Prenatal Choline Supplementation Protects Against Postnatal Neurotoxicity. Society for Neuroscience s.
  4. Shetty AKand Turner DA (2000). Fetal hippocampal transplants containing CA3 cells restore host hippocampal interneuron numbers in a rat model of temporal lobe epilepsy. Soc. Neurosci. Abstr.
  5. Zaman, V., Turner, D.A., Shetty AK (2000). Extensive Post-lesion delay at the time of transplantation adversely influences survival of fetal hippocampal cell grafts in kainate-lesioned CA3 region of adult hippocampus. Society for Neuroscience s.

1998-1999

  1. Shetty, A. K.: Epidermal growth factor responsive hippocampal stem cells: survival, differentiation, and neurite outgrowth in vitro. In Vitro Biology Congress s, 1999.
  2. Shetty, A. K., and Turner, D. A: Fetal hippocampal cell grafting into CA3 region of adult hippocampus following kainic acid lesion rescues hippocampal interneurons from delayed cell death. American Society for Neural Transplantation s, 1999.
  3. Shetty, A. K.: Stem cells from fetal hippocampal field CA3 proliferate in response to either EGF or FGF, and differentiate into field-specific phenotypic neurons. Society for Neuroscience s, 1999.
  4. Croft C. M. andShetty, A. K.: In vitro proliferation and differentiation of embryonic day 15 cortical stem cells responsive to EGF and FGF. Society for Neuroscience s, 1999.
  5. Zaman, V., Turner, D.A. and Shetty, A. K.: Survival of fetal neural transplants in lesioned CA3 region of hippocampus depends upon cell specificity. American Society for Neural Transplantation s, 1999.
  6. Zaman V., Turner, D. A. andShetty, A. K.: Enhanced integration of fetal neural grafts in lesioned CA3 of adult hippocampus depends upon specificity of donor cells. Soc. Neurosci. Abstr., 1999.
  7. Shetty, A. K., Phillips Y. D., and Turner, D. A.: Kainic acid lesion-induced sprouting of mossy fibers into the dentate supragranular layer is diminished in aged rats. Society for Neuroscience s, 1998.

1996-1997

  1. Shetty, A. K., Phillips Y. D., and Turner, D. A.: Brain-derived neurotrophic factor enhances survival and differentiation of neurons derived from postnatal hippocampal stem cells. Soc. Neurosci. Abstr., 1997.
  2. O. A. Roberts,Shetty, A. K., Phillips, Y. D.and Turner, D.A: Effect of donor age on the responsiveness of hippocampal stem cells to EGF. Society for Neuroscience s, 1997.
  3. Shetty, A. K., and Turner, D. A.: Axonal growth of EGF-responsive hippocampal stem cells following grafting onto organotypic hippocampal slices. Intl. Society for Neural Transplantation Abstr., 1997.
  4. Shetty, A. K. and Turner, D. A.: Age-related decrease in rat hippocampal non-pyramidal neurons expressing glutamic acid decarboxylase and calcium binding proteins. Soc. Neurosci. Abstr., 1996.
  5. Austin, M. A., Shetty, A. K.and Turner, D. A.: Integration of mouse postnatal hippocampus progenitor cells following grafting into organotypic hippocampal slices. Society for Neuroscience s, 1996.

1994-1995

  1. Shetty, A. K. and Turner, D. A.: Fetal hippocampal transplants in kainate lesioned hippocampus establish specific connections and reduce supragranular sprouting of host mossy fibers. Soc. Neurosci. Abstr., 1995.
  2. Bulsara, K. R., Pyapali, G. K., Shetty, A. K. and Turner, D. A.: Intracellular dendritic analysis of dentate granule cells following unilateral entorhinal cortex lesions. Society for Neuroscience s, 1995.
  3. Shetty, A. K.and Turner, D. A.: Hippocampal fetal graft integration peaks at 4 days post-lesion following unilateral hippocampal kainic acid lesions in rats. 367.5, Society for Neuroscience s, 20:878, 1994.
  4. Clarke, S. R., Shetty, A. K.and Turner, D. A.: Nestin expression in normal and lesioned adult rat hippocampus. 296.8, Society for Neuroscience s, 20:698, 1994.
  5. Shetty, A. K. and Turner, D. A.: Survival and dispersion of fetal hippocampal grafts following hippocampal kainate lesions. American Society for Neural Transplantation s, 1:15, 1994.

1992-1993

  1. Shetty, A. K., Madison, R. D., Bradley, J. AND Turner, D. A.: 5'-bromodeoxyuridine as prelabel for the analysis of survival and migration of fetal hippocampal suspension grafts. 544.2, Society for Neuroscience s, 19:1317, 1993.
  2. Shetty, A. K., Burrows, R. C., and Phillips, D. E.: Altered development of dopaminergic neurons in substantia nigra following ethanol exposure. 470.4, Society for Neuroscience s, 18:1114, 1992.
  3. Burrows, R. C., Shetty, A. K. and Phillips, D. E.: Effect of in utero ethanol exposure on the   morphological development of the oculomotor nucleus. 470.1, Society for Neuroscience s, 18:1114, 1992.

1990-1991

  1. Shetty, A. K. and Phillips, D. E.: Effect of in utero ethanol exposure on the development of   Bergmann glia in rat cerebellum. 635.12, Society for Neuroscience s, 17:1598, 1991.
  2. Shetty, A. K., Gopinath, G. and Tandon, P. N.: Morphology of substantia nigra transplants in striatum following long-term survival. 3rd IBRO meeting s, 1991.
  3. Shetty, A. K., Gopinath, G. and Tandon, P. N.: Rapid aging of neurons in nigral transplants. 123, 8th Biennial meeting of the International Society for Developmental Neuroscience, (International J. of Developmental Neuroscience - Program and s Supplement, 101), 1990.
  4. Shetty, A. K., Gopinath, G. and Tandon, P. N.: Intrastriatal nigral transplants: Long term graft viability and fine structure. International Neural Regeneration and Neural Transplantation Conference s,Academy of Medicine, Singapore, 1990.

 

Ashok K. Shetty

Professor & Director

 

  • : (254) 771-6804

  • DEPARTMENTDepartment of Molecular and Cellular Medicine
    Texas A&M Health Science Center College of Medicine
  • COUNTRY USA