Publications

ORIGINAL COMMUNICATIONS IN REVIEWED JOURNALS AND SYMPOSIUM PROCEEDINGS:

  • Das, KM and Das, PC:  Evaluation of blood pressure level as an index  for  the degree of stenosis of the mitral orifice.  Calcutta Medical Journal 64: 12: 366, l967.
  • Das, KM and Das, PC:  Electrocardiographic changes in viral hepatitis  and their correlation with the levels of serum bilirubin and transaminases.  Indian Heart Journal 21: 105: 113, 1969.
  • Das, KM and Eastwood, MA:  Effects of iron and calcium on salicylazosulfapyridine metabolism.  Scottish Med. Journal l8: 45, 1973.
  • Das, KM, Eastwood, MA, McManus, JPA and Sircus, W:  Adverse reactions  during salicylazosulfapyridine therapy and the relationship with drug metabolism and acetylator phenotype. New Engl. J. Med. 289: 491, 1973.
  • Das, KM, Eastwood, M.A., McManus, J.P.A. and Sircus, W.:  The metabolism of salicylazosulfapyridine in ulcerative colitis. I. The relationship between  metabolites and response to treatment of in- patient.  Gut 14: 631, l973.
  • Das, KM, Eastwood, M.A., McManus, J.P.A. and Sircus, W.:  The metabolism of salicylazosulfapyridine in ulcerative colitis. II. The relationship  between  metabolites and the progress of the disease studied in out-patients.  Gut 14: 637, 1973.
  • Das, KM, Eastwood, M.A., McManus, J.P.A. and Sircus, W.:  The role of the  colon in the metabolism of salicylazosulfapyridine.  Scand. J. Gastroenterol. 9: 137, 1974.
  • Das, KM:  Iatrogenic alimentary disorders.  J. Ind. M.A. 63: 125-129, 1974.
  • Das, KM and Sternlieb, I.:  Salicylazosulfapyridine in inflammatory bowel disease.  Amer. J. Dig. Dis. 971-976, 1975.
  • Das, KM and Eastwood, M.A.:  Acetylation  polymorphism of sulfapyridine  in patients with ulcerative colitis and Crohn's disease.  Clinical. Pharmacol. Ther. 18: 514, 1975.
  • Eastwood, MA and Das, KM:  The treatment of ulcerative colitis with sulfasalazine.  British J. Hosp. Med. 142, 1975.
  • Das, KM:  Sulfasalazine metabolism in patients with Crohn's disease.  In Proceedings of the Workshop on Crohn's Disease, Leiden, eds., I.T. Weterman, A.S. Pena, C.C. Booth.  Excerpta Medica 161-171, l975.
  • Das, KM and Erber, WF:  Clindamycin associated colitis.  Ann. Intern. Med. 82: 426, 1975.
  • Das, KM and Dubin, R:  Clinical pharmacokinetics of sulfasalazine. Clinical Pharmacokinetics 1: 406-524, 1976.
  • Das, KM, Morecki, R, Nair, P and Berkowitz, J:  Idiopathic proctitis.    The morphology of proximal mucosa and its clinical significance. Amer. J. Dig. Dis. 22: 524, 1977.
  • Cowan, GO, Das, KM and Eastwood, MA:  Further studies of salicylazosulfapyridine metabolism in the treatment of ulcerative colitis.  Brit. Med. J. a:1057, 1977.
  • Das, KM, Erber, WF and Rubinstein, A:  Immunohistochemical changes in   morphologically involved and uninvolved colonic mucosa with idiopathic proctitis.  J. Clin. Invest. 59, 1977.
  • Das, KM:  Sulfasalazine revisited. Gastroenterology 75: ll8l, l978.
  • Rubinstein, A, Das, KM, Melamed, J and Murphy, RA:  Comparative analysis of systemic immunological parameters in ulcerative colitis and idiopathic proctitis:  Effects of sulfasalazine in vivo and in  vitro.  Clin. Exp. Immunol. 33: 217-224, 1978.
  • Das, KM, Dubin, R and Nagai, T:  Isolation and characterization of colonic  tissue  bound antibodies from patients with idiopathic ulcerative colitis.  Proc. Natl. Acad. Sci. 75: 4528-4532, 1978.
  • Das, KM, Chowdhury, JR, Zapp, B and Fara, JW:  Small bowel absorption of sulfasalazine and its hepatic metabolism in humans, cats and rats.  Gastroenterology 77: 280, 1979.
  • Ali, M, Weinstein, J, Biempica, L, Halpern, A and Das, KM:  Cronkhite-Canada Syndrome:  Report of a case of bacteriologic and electron microscopic studies.  Gastroenterology 79: 731, 1980.
  • Das, KM: The management of idiopathic ulcerative colitis. Tropical Gastroenterology 1: 185-192, 1980.
  • Das, KM, Valenzuela, I and Morecki, R:  Crohn's disease lymph node homogenates produce murine lymphoma in athymic mice.  Proc. Natl. Acad. Sci., U.S.A. 77: 588-592, 1980.
  • Sicklick, MJ, Rubinstein, A, Melamed, J and Das, KM:  Circulating immune  complexes in inflammatory bowel disease.  Correlation with clinical course.  Tropical Gastroenterology 2: 115-119, 1981.
  • Nagai, T and Das, KM: Demonstration of an assay for specific cytolytic  antibody in sera from patients with ulcerative colitis.  Gastroenterology 80: 1507-1512, 1981.
  • Nagai, T and Das, KM:  Detection of colonic antigen(s) in tissues from  ulcerative colitis using purified colon-tissue bound IgG (CCA- IgG).  Gastroenterology 81: 463-470, 1981.
  • Shafii, A, Sopher, S, Lev, M and Das, KM:  Presence of an antibody to revertant form of cell wall deficient bacterial variant in sera from patients with Crohn's disease.  Lancet 2: 332-334, l981.
  • Shafii, A, Roy-Chowdhury, J and Das, KM:  Absorption, enterohepatic circulation and excretion of 5-aminosalicyclic acid in rats.  Amer. J. Gastro. 77: 297-299, 1982.
  • Williams, SE, Valenzuela, I, Kadish, AS and Das, KM:  Glomerular immune complex formation and induction of lymphoma in athymic nude mice by Crohn's disease tissue filtrates.  J. Lab. Clin. Med. 99: 827-837, 1982.
  • Kressner, MS, Williams, SE, Biempica, L and Das, KM: Salmonellosis  complicating ulcerative colitis.  JAMA 248: 584-585, 1982.
  • Taffet, SL and Das, KM:  Desensitization of patients with inflammatory bowel disease to sulfasalazine.  Amer. J. Med. 73: 520- 524, 1982.
  • Das, KM:  Pharmacotherapy of inflammatory bowel disease.  Part  1. Sulfasalazine. Postgraduate Medicine 74(6): 141-151, 1983.
  • Das, KM, Valenzuela, I, Williams, SE, Soeiro, R, Kadish, AS and Baum, SG:  Studies of the etiology of Crohn's disease using athymic nude mice.  Gastroenterology 84: 2133-2143, 1983.
  • Bagchi, S and Das, KM:  Detection and partial characterization of Crohn's  disease tissue specific proteins recognized by Crohn's disease sera.  Clin. Exp. Immun. 55: 41-48, 1984.
  • Zuckerman, MJ, Valenzuela, I, Williams, SE, Kadish, AS and Das, KM:  Persistence of an antigen recognized by Crohn's disease sera during in vivo passage of a Crohn's disease induced lymphoma in athymic nude mice.  J. Lab. Clin. Med. 104: 69-76, 1984.
  • Zuckerman, MJ, Taffet, SL, Kadish, AS and Das, KM:  Cell-wall defective bacteria and Crohn's disease:  Studies using athymic nude mice.  Amer. J. Gastroenterol.  79: 104-108, 1984.
  • Weiner, SN, Das, KM, Gold, M, Stollman, Y and Bernstein, LG:  Demonstration of an internal pancreatic fistula by computed tomography.  Gastrointestinal Radiology.  9: 123-125, 1984.
  • Das, KM, Kadono, Y and Fleischner, GM:  Antibody-dependent cell-mediated cytotoxicity by sera from patients with idiopathic ulcerative colitis:  Its relationship to disease activity and response to total colectomy.  Amer. J. Med. 77:791-796, 1984.
  • Koutras, A, Daum, F, Das, KM, Markowitz, J, Duffy, L, Aiges, H, Atkinson, M and Fisher, SE.  Sulfasalazine and renal tubular function.  J. Pediatr Gastroenterol. Nutr. 4:103-106, 1985.
  • Takahashi, F and Das, KM:  Isolation and characterization of a colonic  autoantigen specifically recognized by colon tissue-bound IgG from idiopathic ulcerative colitis.  J. Clin. Invest. 76:311-318, 1985.
  • Das, KM, Simon, MR, Valenzuela, I, Weinstock, J and Marcuard, SMP:  Serum antibodies from patients with Crohn's disease and from their household members react with murine lymphomas induced by Crohn's disease tissue filtrates. J. Lab. Clin. Med. 107:95-100, 1986.
  • Manzione, N.C. and Das, KM:  An immunofluorescence assay using Crohn's  disease tissue injected athymic nude mouse lymph nodes in the diagnosis of inflammatory bowel diseases.  Amer. J. Med. 80:1060-1066, 1986.
  • O'Morain, C, Abelow, AC, Chervu, LR, Fleischner, GM and Das, KM:  Chromium 51-ethylenediaminetetraacetate test:  A useful test in the assessment  of inflammatory bowel disease. J. Lab. Clin. Med. 108:430-435, 1986.
  • Bagchi, S, Baral, B and Das, KM:  Isolation and characterization of Crohn's disease tissue-specific glycoprotein(s). Gastroenterology 91:326-332, 1986.
  • Pena, AS, Kuiper, I, Walvoort, HC, Verspage, HW, Weterman, IT, Ruitenberg, EJ and Das, KM:  Seropositivity in Dutch Crohn's disease patients  against primed nude-mouse lymph nodes and the difference with lymphocytotoxic antibodies. Gut 27:1426-1433, 1986.
  • Manzione, NC, Bagchi, S and Das, KM:  Demonstration of Crohn's disease  tissue-specific proteins by an enzyme linked immunosorbent assay (ELISA).  Dig. Dis. and Sci. 32:593-597, 1987.
  • Manzione, NC, Das, KM, Wolkoff, AW and Carnevale, N:  Unusual sites of variceal bleeding.  J. Clin. Gastro. 9:40-42, 1987.
  • Das, KM, Sakamaki, S, Vecchi, M and Diamond, B.  The production and characterization of monoclonal antibodies to a human colonic antigen associated with ulcerative colitis: Cellular localization of the antigen using the monoclonal antibody.  J. Immunol. 139:77-84, 1987.
  • Vecchi, M, Sakamaki, S, Diamond, B, Novikoff, AB, and Das, KM:  Development of monoclonal antibody specifically reactive to gastrointestinal  goblet cells.  Proc. Natl. Acad. Sci. (USA)  84:3425-3429, 1987.
  • Das, KM: Some current perspectives on the etiology and pathogenesis of inflammatory bowel disease.  Einstein Quart. J. Biol. Med. 5:43-51, 1987.
  • Vecchi, M, Sakamaki, S, Das, KM:  Organ specificity and colonic distribution of the Mr 40,000 colonic protein associated with ulcerative colitis: Tissue localization using a specific monoclonal antibody.  In "Inflammatory Bowel Disease: Current Status and Future Approach", International Congress series 775, Excerpta Medica 455-460, 1988.
  • Das, KM, Zuckerman, M, Shafritz, A, Vecchi, M:  Athymic nude (nu/nu) Mice: An experimental animal for studies of the etiology of Crohn's Disease.  In "Inflammatory Bowel Disease: Current Status and Future Approach", International Congress series 775, Excerpta Medica 455-460, 1988.
  • Das, KM, Sakamaki, S, Vecchi, M: Ulcerative colitis: specific antibodies against a colonic epithelial Mr 40,000 protein.  Immunological Investigations, 18:459-472, 1989.
  • Cappell, MSand Das, KM.  Rapid development of pancreatitis following reuse of 6-mercaptopurine.  J Clin Gastroenterol, 11:679-681, 1989.
  • Zuckerman, MJ, Williams, SE, Bura, R, Das, KM and Sachar, D:  Sero-reactivity in inflammatory bowel disease:  The recognition of Crohn's disease tissue primed nude mouse lymphoid tissue in an inter-institutional blinded study:  Clin. J. Gastroenterology, 11:639-44, 1989.
  • Das, KM:  Primary sclerosing cholangitis.  Autoimmunity Forum Gastroenterology, 1(3):14-15, December 1989.
  • Mazumdar, S, Das, KM: Vasoactive intestinal peptide in the normal and diseased gastrointestinal tract.  Natl. Med. Jrnl. of India, 2(4):176-180, 1989.
  • Das, KM, Vecchi, M, Sakamaki, S: A shared and unique epitope(s) on human colon, skin and biliary epithelium detected by a monoclonal antibody.  Gastroenterology, 98:464-469, 1990.
  • Zinberg J, Molinas, S, Das, KM: Double blinded, placebo controlled clinical study of olsalazine in the treatment of symptomatic ulcerative   colitis.  The American Journal of Gastroenterology, 85(5):562-66, 1990.
  • Hirsch, RE, Lin, MJ, Das, KM:  Estimation of 5-aminosalicylic acid and its metabolite in human serum by front-face fluorometry: a simple and sensitive method.  J. Lab. Clin. Med., 116(1):45-50, 1990.
  • Takahasi, F, Shah, H, Wise, L, Das, KM  Circulating antibodies against human colonic extract enriched with a 40 kDa protein in patients with ulcerative colitis.  Gut, 31(9):1016-1020, 1990.
  • Chitayet, D, Marion, RW, Squillante, L and Das, KM:  Detection and enumeration of colonic mucosal cells in amniotic fluid using a colon epithelial specific monoclonal antibody.  Prenatal Diagnosis, 10:725-732, 1990.
  • Das, KM, Vecchi, M, Novikoff, A, Mazumdar, S, Novikoff, PM  Hybridomas using athymic nude mouse injected with Crohn's disease (CD) tissue filtrate:  Immunoreactivity of the hybridomas with CD sera.  Amer. J. of Pathology, 136(6):1375-1382, 1990.
  • Bhatt, BD, Cappell, MS, Smilow, PC, Das, KM  Recurrent Massive Upper Gastrointestinal Hemorrhage Due to Strongyloides stercoralis Infection.  Amer. J. Gastroenterology, 85:1034-1036, 1990.
  • Das, KM  Reactivity of aggregated immunoglobulin in Crohn's Disease.  Gastroenterology, 99(3):904, 1990
  • Geller, A, Das, KM  Etiology of inflammatory bowel disease.  Current Science, 6:561-564, 1990.
  • Ebert, EC, Bhatt, BD, Liu, S, Das, KM  Induction of suppressor cells by mycobacterium paratuberculosis antigen in inflammatory bowel disease.  Clinical Exp Immunology, 83:320-325, 1991.
  • Biancone, L, Wise, LS, Das, KM  The presence in experimental animals of a colon specific Mr 40,000 protein(s) with relevance to ulcerative colitis.  Gut, 32:504-508, 1991.
  • Das, KM  Serum and tissue autoantibodies to colonic epithelium in ulcerative colitis.  Gut, 32:1569, 1991.
  • Das, KM, Vecchi, M, Squillante, L, Dasgupta, A, Henke, M, Clapp, N.  Mr 40,000 human colonic epithelial protein expression in colonic mucosa and presence of circulating anti-Mr 40,000 antibodies in cotton top tamarins with spontaneous colitis.  Gut, 33:48-54, 1992.
  • Mazumdar, S, Das, KM  Immunocytochemical localization of vasoactive intestinal peptide and substance P in the colon from normal subjects and patients with inflammatory bowel disease.  Amer. J. Gastroenterology, 87:176-181, 1992.
  • Das, KM, Squillante, L, Robertson, F.  Expression of the Mr 40,000 protein in DLD-1 colon cancer cells and the effect of cytokines.  Clin. Exp. Immunol., 88:138-142, 1992.
  • Das, KM, Squillante, L, Chitayet, D, Kalousek, DK.  Simultaneous appearance of a unique common epitope in fetal colon, skin and biliary epithelial cells:  A possible link for extracolonic manifestations in ulcerative colitis.  J. Clin. Gastro., 15:311-316, 1992.
  • Carson, JL, Strom, BL, Duff, A, Gupta, A, Shaw, M, Das, KM.  The feasibility of studying drug induced acute hepatitis using Medicaid data.  Clinical Pharmacology and Therapeutics, 52:214-219, 1992.
  • Carson, JL, Strom, BL, Duff, A, Gupta, A,  Shaw, M, Lundin, FE, Das, KM.  Acute liver disease associated with erythromycins,  sulfonamides and tetracyclines.  Ann. of  Int.  Med., 119:576-583, 1993.
  • Carson, JL, Strom, BL, Duff, A, Gupta,  A, Das, KM.  Safety of NSAIDS with respect to acute liver disease.  Arch. Int.  Med., 153:1331-1336, 1993.
  • Das, KM, Squillante, L, Robertson, FM  Amplified expression of intercellular adhesion molecule-1 (ICAM-1) and Mr 40K protein by DLD-1 colon tumor cells by interferon-gamma.   Cellular Immunology, 147:215-221, 1993.
  • Halstensen, TS, Das, KM, Brandtzaeg, P.  Epithelial deposits of immunoglobulin G1 and activated complement co-localize with the Mr 40K colonic autoantigen in ulcerative colitis.  Gut,  34:650-657, 1993.
  • Das, KM, Dasgupta, A, Mandal, A.  Autoimmunity to cytoskeletal protein tropomyosin(s):  a new clue to the pathogenetic mechanism for ulcerative colitis.  J. Immunology, 150:2487-2493, 1993.
  • Biancone, L, Das, KM, Roberts, AI, Ebert, EC.  Ulcerative colitis sera recognize the Mr 40K protein on colonic adenocarcinoma cells for antibody dependent cellular cytotoxicity.  Digestion, 54:237-242, 1993.
  • Das, KM.  Autoimmunity in inflammatory bowel disease.  Canadian J. Gastroenterol., 7:102-109, 1993.
  • Das, KM, Prasad, I, Garla, S, Amenta, P.  Detection of a shared colon epithelial epitope on Barrett’s epithelium by a novel monoclonal antibody.  Ann. Int. Med., 120:753-756, 1994.
  • Mandal, A, Dasgupta, A, Jeffers, L, Squillante, L, Hyder, S, Reddy, R, Schiff, E, Das, KM.  Autoantibodies in sclerosing cholangitis against a shared epitope in biliary and colon epithelium.  Gastroenterology, 106:185-192, 1994.
  • Dasgupta, A, Mandal, A, Das, KM.  Circulating immunoglobulin G1 antibody in patients with ulcerative colitis against the colonic epithelial protein detected by a novel monoclonal antibody.  Gut, 35:1712-1717, 1994.
  • Bhagat, S, Das, KM.  A shared and unique peptide in human colon, eye and joint detected by a novel monoclonal antibody.  Gastroenterology, 107:103-108, 1994.
  • Griffel, L, Das, KM.  Nicotine and ulcerative colitis.  National Medical Journal of India, 7(5):222-223, 1994.
  • Biancone, L, Mandal, A, Yang, H, Dasgupta, T, Paoluzi, AO, Marcheggiano, A, Paoluzi, P, Pallone, F, Das, KM.  Production of immunoglobulin G and G1 antibodies to cytoskeletal protein by lamina propria cells in ulcerative colitis.  Gastroenterology, 109:3-12, 1995.
  • Hassan, T, Kanisawa, Y, Meyers, S, Dasgupta, A, Das, KM.  Expression of a unique protein on colon cancer cells that reacts with a novel monoclonal antibody and ulcerative colitis serum.  Clin. and Exp. Immunol., 100:457-462, 1995.
  • Halstensen, TS., Das, KM, Brandtzaeg, P.  Epithelial deposits of immunoglobulin G1 and activated complement co-localize with the "Mr 40kD" putative auto-antigen in ulcerative colitis.  Advanc. Exp. Med. Biol., 371B:1273-1276, 1995.
  • Latella, G, Fonti, R, Caprilli, R, Marcheggiano, A, Magliocca, F, Das, KM, Gambus, G, Sambuy, Y.  Characterization of the mucins produced by normal human colonocytes in primary culture.  Int. J. Colorect. Dis., 11:76-83, 1996.
  • Shah, U, Dasgupta, A, Das, KM.  Development of ulcerative colitis-associated anti-idiotype antibody using a novel monoclonal antibody against a colonic autoantigen.  Cellular Immunol. 166:154-157, 1995.
  • Carp, JM, Onuma, E, Das, KM, Gottlieb, AB.  Intravenous cyclosporine therapy in the treatment of pyoderma gangrenosum secondary to Crohn's disease.  CUTIS, 60:135-138, 1997.
  • Pantuck, AJ, Bancila, E, Das, KM, Amenta, PS, Cummings, KB, Marks, M, Weiss, RE.  Adenocarcinoma of the urachus and bladder express a unique colonic epithelial epitope:  an immunohistochemical study.  J. Urology, 158:1722-1727, 1997.
  • Geng, X, Biancone, L, Dai, HH, Lin, JJ-C, Yoshizaki, N, Pallone, F, Das, KM.  Tropomyosin isoforms in intestinal mucosa:  production of autoantibodies to tropomyosin isoforms in ulcerative colitis.  Gastroenterology, 114:912-922, 1998.
  • Pantuck, AJ, Murphy, DP, Amenta, PS, Das, KM, Cummings, KB, Weiss, RE.  The monoclonal antibody 7E12H12 can differentiate primary adenocarcinoma of the bladder and prostate.  B.J. Urology.  82:426-430, 1998.
  • Das, KM.  Relationships of extracolonic involvement in inflammatory bowel disease:  New insights into autoimmune pathogenesis.  Dig. Dis. Sci.  44:1-13, 1999.
  • Murphy, DP, Pantuck, AJ, Amenta, PS, Das, KM, Cummings, KB, Keeney, GL, Weiss, RE.  Female urethral adenocarcinoma:  immunohistochemical evidence for more than one tissue of origin.  J. Urology, 161:1881-1884, 1999.
  • Gurudu, SR, Griffel, LH, Gialanella, RJ, Das, KM.  Cyclosporine therapy in inflammatory bowel disease, short term and long term results.  J. Clin. Gastro. 29:151-154, 1999.
  • Kesari, KV, Yoshizaki, N, Geng, X, Lin, JJ-C, Das, KM.  Externalization of tropomyosin isoform 5 in colon epithelial cells.  Clin. Exp. Immunol. 118:219-227, 1999.
  • Griffel, L.., Amenta, P, Das, KM.  Use of a novel monoclonal antibody in diagnosis of Barrett’s esophagus.  Dig. Dis. Sci. 45:40-48, 2000.
  • Badve, S, Logdberg, L, Sokhi, R, Sigal, SH, Botros, N, Chae, S, Das, KM, Gupta, S. An antigen reacting with das-1 monoclonal antibody is ontogenically regulated in diverse organs including liver and indicates sharing of developmental mechanisms among cell lineages.  Pathobiology.  68:76-86, 2000.
  • Oh, CJ, Das, KM, Gottlieb, AB.  Treatment with anti-TNF-alpha monoclonal antibody improves psoriasis.  J. Amer. Acad. Derm., 42:829-830, 2000.
  • Onuma, EK, Amenta, PS, Ramaswamy, K, Lin, JJ-C, Das, KM.  Autoimmunity in ulcerative colitis: a predominant colonic mucosal B cell response against human  tropomyosin isoform 5.  Clin. Exp. Immunol.  121:466-471, 2000.
  • Das, KM, Farag, SA.  Current medical therapy of inflammatory bowel disease.  World J. Gastro.  6:483-489, 2000.
  • Glickman, JN, Wang, H, Das, KM, Goyal, RK, Spechler, SJ, Antonioli, D, Odze, RD. Phenotype of Barrett’s esophagus and intestinal metaplasia of the distal esophagus and gastroesophageal junction.  Am. J. Surg. Pathol. 25:87-94, 2001.
  • Onuma, EK, Amenta, PS, Jukkola, AF, Mohan,V, Borra, S, Das, KM.  A phenotypic change of small intestinal epithelium to that of colonocytes in small intestinal adenomas and adenocarcinomas.  Am. J. Gastro.  96:2480-2485, 2001.
  • Dasgupta, A, Kesari, KV, Ramaswamy, KK, Amenta, PS, Das, KM.  Oral administration of unmodified colonic but not small intestinal antigens protects rats from hapten-induced colitis.  Clin. Exp. Immunol. 125:41-47, 2001.
  • Dasgupta, A, Ramaswamy K, Giraldo, J, Taniguchi, M, Amenta, PS, Das, KM.  Colon epithelial cellular protein induces oral tolerance in the experimental model of colitis by trinitrobenzene sulfonic acid.  J. Lab and Clin. 138:257-269, 2001.
  • Taniguchi, M, Geng, X, Glazzier, KD, Dasgupta, A, Lin, JJ.-C, Das, KM.  Cellular immune response against tropomyosin isoform 5 in ulcerative colitis.  Clin. Immunol. 101:289-295, 2001.
  • Zimmerman, RL., Das, KM., Fogt, F, Murakata, LA.  The Das-1 immunostain is useful for discriminating metastatic colon adenocarcinoma from cholangiocarcinoma and hepatocellular carcinoma.  Oncol Rep.  9:1369-1372, 2002.
  • Lin, JL-C., Geng, X, Das-Bhattacharya, ., Yu, J-R, Reiter, RS, Sastri, B, Glazier, KD, Mirza, ZK, Wang, KK, Amenta, PS, Das, KM., Lin, JJ-C.  Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer.  Gastroenterology, 123:152-162, 2002.
  • Zimmerman, RL, Das, KM, Burke, MA, Young, NA, Solomides, CC, Bibbo, M.  The clinical utility of the Das-1 monoclonal antibody in identifying adenocarcinoma of the colon metastatic to the liver in fine-needle aspiration tissue.  Cancer 96:370-373, 2002.
  • Rogge-Wolf, C, Seldenrijk, CA, Das, KM, Timmer, R, Breumelhof, R, Smout,  AJPM, Amenta, PS, Griffel, LH.  Prevalence of mAbDAS-1 positivity in biopsy specimens from the esophagogastric junction.  Am J Gastro., 97:2979-2985, 2002.
  • Fisher, RS, Bromer, MQ, Thomas, RM, Cohen, S, Krevsky, B, Horwitz, B, Glazier, KD., Das, K, Das, KM.  Predictors of recurrent specialized intestinal metaplasia after  complete laser ablation.  Am J Gastro., 98:1945-1951, 2003.
  • Biancone, L, Palmieri, G, Lombardi, A, Colantoni, A, Tonelli, F, Das, KM., Pallone, F.  Tropomyosin expression in the ileal pouch: A relationship with the development of pouchitis in ulcerative colitis.  Amer J. Gastro., 98:2719-2726, 2003.
  • Mirza ZK, Das KK, Slate J, Mapitigama RN, Amenta PS, Griffel, LH, Ramsundar L, Watari J, Yokota K, Tanabe H, Sato T, Kohgo Y, Das KM.  Gastric intestinal metaplasia as detected by monoclonal antibody is highly associated with gastric adenocarcinoma.  GUT, 52:807-812, 2003.
  • Subbaramaiah, K, Yoshimatsu, K, Scherl, E, Das, KM., Glazier, KD, Golijanin, D, Soslow, RA, Tanabe, T, Naraba, H, Dannenberg, A.J.  Microsomal prostaglandin E synthase-1 overexpressed in inflammatory bowel disease.  Evidence for involvement of the transcription factor Egr-1.  J Biol Chem., 279:12647-58, 2004.
  • Glazier, KD, Palance, AL, Griffel, LH, Das, KM.  The ten-year single-center experience with 6-mercaptopurine in the treatment of inflammatory bowel disease.  J Clin Gastroenterol., 39:21-26, 2005.
  • Ebert EC, Mehta V, Das KM.  Activation antigens on colonic T cells in inflammatory bowel disease.  Clin. Exp. Immunol., 140:157-165, 2005.
  • Kovvali G, Das KM. Hypothesis - Molecular mimicry may contribute to pathogenesis Of ulcerative colitis.  FEBS Letters 579:2261-2266, 2005.
  • Ebert, EC, Geng, X, Lin, J, Das, KM.  Autoantibodies against human tropomyosin isoform 5 in ulcerative colitis destroys colonic epithelial cells through antibody and complement-mediated lysis.  Cell. Immunol., 244:43-49, 2006.
  • Sun JH, Das KK, Amenta PS, Yokota K, Watari J, Sato T, Kohgo Y, Das KM.  Preferential expression of cyclooxygenase-2 in colonic phenotype of gastric intestinal metaplasia: Association with helicobacter pylori and gastric carcinoma.  J Clin Gastro., 40:122-128, 2006.
  • Mirza, ZK, Sastri, B, Lin, JJ-C, Das, KM.  Autoimmunity against human tropomyosin isoforms (hTMs) in ulcerative colitis: localization of specific hTMs in the intestine and extraintestinal organs.  Inflam. Bowel Dis., 12:1036-1043, 2006.
  • Watari, J, Das, KK, Amenta, PS, Tanabe, H, Yasuda, A, Fujiya, M, Saitoh, Y, Yokota, K, Geng, X, Lin, JJ-C, Kohgo, Y, Das, KM.  Effect of eradication of helicobacter pylori on genetic instabilities in gastric intestinal metaplasia.  Aliment Pharmacol Therap., 2:194-202, 2006.
  • Cohen HD, Das KM.  The metabolism of mesalamine and its possible use in colonic diverticulitis as an anti-inflammatory agent.  J Clin Gastro., 40:S150-S154, 2006.
  • Watari, J, Tanaka, A, Tanabe, H, Sato, R, Moriichi, K, Zaky, AH, Okamoto, K, Maemoto, A, Fujiya, M, Ashida, T, Das, KM., Kohgo, Y.  K-ras mutations and cell kinetics in Helicobacter pylori associated gastric intestinal metaplasia:  A comparison before and after eradication in patients with chronic gastritis and gastric cancer.  J Clin Pathol., 60:921-926, 2007.
  • Tatar, E, Das, KM.  Improvement in ulcerative colitis symptoms after use of fish oil enemas.  Gastro and Hepatol., 3:786-787, 2007.
  • Watari, J, Das, KK, Amenta, PS, Tanabe, H, Tanaka, A, Geng, X, Lin, J, Kohgo, Y, Das, KM.  Effect of eradication of Helicobacter pylori on the histology and cellular phenotype of gastric intestinal metaplasia.  Clin Gastro Hepatol., 6:409-417, 2008.
  • Bajpai, M, Liu, J, Geng, X, Souza, RF, Amenta, PS, Das, KM.  Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett’s epithelial cell line.  Lab Investig., 88:643-651, 2008.
  • Trivedi,CD, Mithani, S, Chichili, E, Xing, D, Das, KM.  Long-term safety of 5-aminosalicylates (mesalamine) in the treatment of inflammatory bowel disease.  Gastro. & Hepatol., 4:9-11, 2008.
  • Yantiss, RK, Das, KM, Farraye, FA, Odze, RD.  Alterations in the immunohistochemical expression of Das-1 and CG-3 in colonic mucosal biopsy specimens helps distinguish ulcerative colitis from Crohn’s disease and from other forms of colitis.  Am J Surg Pathol., 32:844-850, 2008.
  • Ebert, EC, Das, KM, Mehta, V, Rezac, C.  Non-response to infliximab may be due to innate neutralizing anti-TNFα antibodies.  Clin Exp Immunol., 154:325-331, 2008.
  • Das, KM, Biancone, L.  Is inflammatory bowel disease an autoimmune disorder?  Inflam Bowel Dis., 14:S97-S101, 2008.
  • Biancone, L, Calabrese, E, Palmieri, G, Petruzziello, C, Onali, S. Sica, GS, Cossignani, M, Condino, G, Das, KM, Pallone, F.  Ileal lesions in patients with ulcerative colitis after ileo-rectal anastomosis:  Relationship with colonic metaplasia.  W J Gastro., 14:5290-5300, 2008.
  • Ebert, E, Panja, A, Das, KM, Praveen, R, Geng, X, Rezac, C, Bajpai, M.  Patients with inflammatory bowel disease may have a transforming growth factor-β-, interleukin (IL)-2- or IL-10-deficient state induced by intrinsic neutralizing antibodies.  Clin Exp Immunol., 155:65-71, 2009.
  • Moriichi, K, Watari, J, Das, KM, Tanabe, H, Fujiya, M, Ashida, T, Kohgo, Y.  Effects of Helicobacter pylori infection on genetic instability, the aberrant CpG island methylation status and the cellular phenotype in Barrett’s esophagus in a Japanese population.  Int J Cancer., 124:1263-1269, 2009.
  • Watari, J, Moriichi, K, Tanabe, H, Sato, R, Fujiya, M, Das, KM, Kohgo, Y.  Differences in genetic instability and cellular phenotype among Barrett’s, cardiac, and gastric intestinal metaplasia in a Japanese population with H. pylori.  Histopathology, 55:261-269, 2009.
  • Hahn HP, Blount PL, Ayub K, Das KM, Souza R, Spechler S, Odze RD.  Intestinal differentiation in metaplastic, non-goblet columnar epithelium in the esophagus.  Am J Surg Pathol., 33:1006-1015, 2009.
  • Das KK, Bajpai M, Kong Y, Liu J, Geng X, Das KM.  Mesalamine suppresses the expression of TC22, a novel tropomyosin isoform associated with colonic neoplasia.  Mol Pharmacol., 76:183-191, 2009.
  • Ebert EC, Geng X, Bajpai M, Pan Z, Tatar E, Das KM.  Antibody to tropomyosin isoform 5 and complement induce the lysis of colonocytes in ulcerative colitis.  Am J Gastroenterol., 104:2996-3003, 2009.
  • Kao, J, Kwok, K, Das, KM.  Inducing and maintaining remission in ulcerative colitis role of high-dose, extended-release mesalamine.  J Clin Gastroenterol, 44:531-535, 2010.
  • Watari J, Sakurai J, Morita T, Yamazaki T, Okugawa T, Toyoshima F, Tanaka J, Tomita T, Kim Y, Oshima T, Hori K, Moriichi K, Tanabe H, Fujiya M, Kohgo Y, Das KM, Matsumoto T, Miwa H.  A case of early Barrett’s adenocarcinoma repeatedly developing multiple metachronous lesions shortly after endoscopic therapy: an analysis for genetic and epigenetic alterations. Gastrointestinal Endoscopy 72:1303-1307, 2010.
  • Lenza C., Das KM.  Mesalamine in the Treatment of Diverticular Disease.  J Clin Gastroenterol, 45:pS53-S61, 2011.
  • Das KM, Kong Y, Bajpai M, Kulkarni D, Geng X, Mishra L, Banerjee D, Hirshfield K. Transformation of Benign Barrett’s Epithelium by Repeated Acid and Bile Exposure over 65 Weeks: A Novel In-Vitro Model. Intl J Cancer.  Intl J Cancer, 128:274-282, 2011.
  • Das KM, Bajpai M.  Phenotypic and molecular changes observed during in-vitro transformation of benign Barrett’s epithelium by acid and bile.  Annals of the NY Acad Sci 1232;210-229, 2011.
  • Das KM, Pickett-Blakely OE, Bajpai M, Amenta PS.  Is the monoclonal antibody, mAb Das-1 likely to help in early recognition of Intestinal Metaplasia (IM) of the esophagus?  Annals of the NY Acad Sci 1232:76-92 2011.
  • Bajpai M, Das KM. What lessons can be learned from the influence of environmental factors on various in vitro models and the cellular phenotype(s) of the non-neoplastic Barrett’s cell line about pathogenesis of Barrett’s epithelium and its progression to neoplasia.  Annals of the NY Acad Sci 1232:18-35 2011.
  • Watari J, Moriichi K, Tanabe H, Kashima S, Nomura Y, Fujiya M, Tomita T, Oshima T, Fukui H, Miwa H, Das KM,  Kohgo Y. Biomarkers predicting development of metachronous gastric cancer after endoscopic resection: an analysis of molecular pathology of Helicobacter pylori eradication.  Int. J. Cancer 130:2349-2358 2012.
  • Bajpai M, Aviv H, Das KM.  Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett’s epithelium.  Molecular Cytogenetics 5;43, 2012.
  • Bajpai M, Kessel R, Bhagat Tushar, Nischal S, Yu Yiting, Verma A, Das KM.  High Resolution Integrative Analysis Reveals Widespread Genetic and Epigenetic Changes After Chronic In-Vitro Acid and Bile Exposure in Barrett’s Epithelium Cells.  Genes, Chromosomes and Cancer  52:1123-1132, 2013.
  • Yu Fang, Xiaoxin Chen, Manisha Bajpai, Amit Verma, Kiron M. Das, Rhonda F. Souza, Katherine S. Garman, Claire L.  Donohoe, Naoimh J. O’Farrell, John V. Reynolds, and Katerina Dvorak.  Cellular origins and molecular mechanisms of Barrett’s esophagus and esophageal adenocarcinoma.  Ann. N.Y. Acad Sci. 1300:187-199, 2013.
  • Michael K. Gibson, Arashinder S. Dhaliwal, Nicholas J. Clemons, Wayne A. Phillips, Katerina Dvorak, Daniel Tong, Simon Law, E. Daniel Pirchi, Jari Räsänen, Mark J. Krasna, Kaushal Parikh, Kausilia K. Krishnadath, Yu Chen, Leonard Griffiths, Benjamin J. Colleypriest, J. Mark Farrant, David Tosh, Kiron M. Das, and Manisha Bajpa.  Barrett’s esophagus:  cancer and molecular biology.  Ann. N.Y Acad Sci. 1300:296-314, 2013.
  • Koushik K. Das, Hong Xiao, Xin Geng,, Carlos Fernandez-del-Castillo, Vicente Morales-Oyarvide, Ebubekir Daglilar, David G. Forcione, Brenna C. Bonds, William R. Brugge, Martha B. Pitman, Mari Mino-Kenudson, Kiron M. Das.  mAb Das-1 is specific for high-risk and malignant intraductal papillary mucinous neoplasm (IPMN).  Gut Online 10.1136, 2013.

Chapters in books/Monograms:

  • Das, KM, Williams, SE, Valenzuela, I and Baum, S:  Induction of lymphoma  in athymic (nu/nu) mice by Crohn's disease tissue filtrates:  A model for the study of Crohn's disease.  In Recent Advances in Crohn's Disease, eds., A.S.  Pena,  I.T. Weterman, C.C. Booth and W. Strober.  Martinus Nijhoff Publishers, Boston, 1981, pp. 266-271.
  • Das, KM, Kadono, Y and Nagai, T:  Ulcerative colitis:  Autoimmune   disease.  In Inflammatory Bowel Disease, eds., D. Rachmilewitz.  Martinus Nijhoff Publishers, Boston, l982, pp. 80-95.
  • Das, KM, Valenzuela, I, Bagchi, S and Williams, SE:  Athymic nude mice  in studies of Crohn's disease.  In Inflammatory Bowel Disease, eds., D.  Rachmilewitz, Martinus Nijhoff Publishers, Boston, 1982, pp. 41-55.
  • Manzione, NC, Bagchi, S and Das, KM:  Etiopathogenesis of inflammatory bowel disease: (a) Etiology of Crohn's disease:  animal transmission studies  and the presence of disease-specific tissue "antigen(s)", and (b) Pathogenesis of ulcerative colitis: immunobiochemical studies. In: Inflammatory Bowel Disease, ed., D. Rachmilewitz, Martinus Nijhoff Publishers, Boston, 1986.
  • Zinberg, J, Vecchi, M, Sakamaki, S and Das, KM:  Intestinal Tissue Associated Antigens in the Pathogenesis of Inflammatory Bowel Disease: Inflammatory Bowel Disease, Tenth International Berzelius Symposium, eds.,  Gunnar Jarnerot, Raven Press, New York, 1987, pp. 67-76
  • Das, KM:  Management of Ulcerative Colitis: in Conn's Current Therapy, Pages 429-435, 1989.
  • Das, KM: Sulfasalazine - in Management of Inflammatory Bowel Disease, Treating IBD: A patient's guide to the medical and surgical management of inflammatory bowel disease, ed. LJ. Brandt & PS Grossman, Raven, 1989.  National Foundation for Ileitis and Colitis, New York, NY.
  • Das, KM: Management of ulcerative colitis:  In Conn's Current Therapy, Pages 441-447, 1990.
  • Das, KM:  Some Current Perspectives on the Etiology and Pathogenesis of Ulcerative Colitis.  In Ulcerative Colitis, ed. Colm O'Morain, CRC Press, Inc., 1990, pages 47-54.
  • Kawanishi, HK, Cappell, MS, Das, KM: GI and Nutritional Complications of AIDS, Ed D. Kotler, Raven Press, 1993.
  • Cappell, MS, Kawanishi, HK, Das, KM:  The Acquired Immunodeficiency Syndrome.  In Immunology and Inflammation:  Basic Mechanisms and Clinical Consequences, Eds L.H. Sigal, Y. Ron, McGraw-Hill, Inc., 1994, N.Y.; pages 441-464.
  • Geller, A, Das, KM:  The Immunopathogenesis of Inflammatory Bowel Disease.  In Immunology and Inflammation:  Basic Mechanisms and Clinical Consequences, Eds L.H. Sigal, Y. Ron, McGraw-Hill, Inc., 1994, N.Y.; pages 691-698.
  • Das, KM, Prasad, I, Garla, S, Amenta, P.  Is There a Common Reactive Epitope Between Colonic and Barrett's Epithelia?  In Giuli, R., Tytgat, G.N.J., DeMeester, T.R., Galmiche, J.P. (eds.) The Esophageal Mucosa, Elsevier, 1994, Amsterdam; pages 1037-1040.
  • Leone, V, Das, KM.  Immune System of the Gastrointestinal Tract.  In Clinical Immunology, Senior Ed. P. Sengupta.
  • Griffel, LH, Das, KM.  Medical Treatment of Inflammatory Bowel Disease.  In Bittar, E.E. (ed.) Principles of Medical Biology, JAI Press, Inc.
  • Griffel, LH, Das, KM.  Inflammatory Bowel Disease.  In Bittar, E.E. (ed.) Principles of Medical Biology, JAI Press, Inc.
  • Das, KM.  Current Perspectives in the Medical Management of IBD.  In Singh, M.M. (ed.) Medicine Update Proceeding of APICON 1999, Vol. 9, Part II, Association of Physicians of India, 1999, Mumbai; 465-476.
  • Das KM, Bajpai M.  Tropomyosins in human diseases:  ulcerative colitis.  In Gunning, P. (ed.)  Tropomyosin, Springer Science+Business Media, LLC, Landes Bioscience, Vol. 644, pp 158-167.
  • Oikonomou I, Das KM. Extraintestinal Manifestations of IBD. In Advanced Therapy in Inflammatory Bowel Disease Vol 1: IBD and Ulcerative Colitis, Third Edition 2011.
  • Watari J, Tanabe H, Moriichi K, Fujiya M, Amenta PS, Miwa H, Kohgo Y, Das KM.  Effects of Helicobacter pylori infection on the histology, cellular phenotype, K-ras mutations, and cell kinetics and gastric intestinal metaplasia in patients with chronic gastritis and gastric cancer. In Gastritis and Gastric Cancer- New Insights in Gastroprotection, Diagnosis and Treatments Edited by Paola Tonino.  Sep 2011 Chapter 12, 217-242.
  • Abergel JR, Das KM. Inflammatory Bowel Disease.  In Geriatric Gastroenterology, Edited by C.S. Pitchumoni, T.S. Dharmarajan, Chapter 50, 483-491, 2012.
  • Watari Jiro, Moriichi Kentaro, Tanabe Hiroki, Fujiya Mikihiro, Miwa Hirota, Kohgo Yutaka, Das Kiron M.  Intestinal Metaplasia Related to Gastric Cancer:  An Outcome Analysis of Biomarkers for Early Detection.  In Current Topics in Gastritis – 2012, edited byGyula Mozsik, Chapter 6, 97-111, January 2013

Other Articles (Reviews, Editorials, Etc)

  • Das, KM: Salicylazosulfapyridine in clinical practice.  Gastroenterology 66: 326, 1974.
  • Chowdhury, JR, Das, K and Das, KM:  Primary liniatus plastica of the colon.  Diseases of the Colon and Rectum 18: 332, 1975.
  • Farkas, PS, Knapp, AB and Das, KM:  Existaxis:  An overlooked diagnosis in presumed variceal bleeding.  J. Clin. Gastroenterol. 4: 49-51, 1982.
  • Das, KM: Sulfasalazine revisited.  Inflammatory Bowel Disease News, National Foundation for Ileitis and Colitis, Inc., 31: 1-3, 1982.
  • Taffet, SL and Das, KM:  Sulfasalazine:  Adverse effects and desensitization.  Digestive Disease and Sciences 28(9): 833-842, 1983.
  • Manzione, NC, Kram, M, Kram, E, Das, KM: Turner's Syndrome and Inflammatory Bowel Disease: A case report with immunologic studies, Amer. J. Gastroenterology, 83:1294-1298, 1988.
  • Das, KM.  Sulfasalazine therapy in inflammatory bowel disease. Gastroenterology Clinics of North America, 18:1-20, 1989.
  • Dasgupta, A, Mandal, A, Henke, M, Clapp, N, Das, KM.  Cotton-top tamarins with spontaneous colitis contain circulating antibodies reactive to human colonic Mr 40K protein, an autoantigen associated with human ulcerative colitis (UC).  Agents Actions, Special Conference Issue, 41:C250-C251, 1994.
  • Griffel, LH, Das, KM.  The smoke is beginning to clear (selected summaries).  Inflammatory Bowel Diseases, 2:159-1607, 1996.
  • Griffel, LH, Das, KM.  Ulcerative colitis:  pathogenesis, diagnosis, and current treatment.  J. Assoc. for Acad. Minority Physicians. 7:63-69, 1996.
  • Onuma, EK, Das, KM.  Current Medical Therapy of Inflammatory Bowel Disease.  Pract. Gastro.  22:19-30, 1998.
  • Botros, N, Pickover, L, Das, KM.  “Image of the Month”.  Use of infliximab in the treatment of pyoderma gangrenosum associated with ulcerative colitis.  Gastroenterology 118:654, 2000.
  • Kovvali, G, Shiff, S, Telang, N, Das, K, Kohgo, Y, Narayan, S, Honghua, L.  Carcinogenesis: The more we seek to know the more we need to know: challenges in the post genomic era.  J Carcinogen, 2:1, 2003.
  • Shen EH, Das KM.  Current Therapeutic Recommendations - Infliximab for Ulcerative Colitis.  J Clin Gastroenterol., 38:741-745, 2004.
  • Das KM.  “Is foe your friend?”.  Inflamm Bowel Dis., 10:693, 2004.
  • Sun JH, Das KM.  Therapeutic recommendations - Low dose oral methotrexate for maintaining Crohn’s disease.  Remission: where we stand.  J Clin Gastro., 39:751-756, 2005.
  • Kabis, S, Schneider, S, Das, KM, Zehring, W, Zachow, R.  Cases for medical physiology small group discussions.  MedEdPORTAL, 2007.
  • Trivedi, CD, Das, KM.  Emerging Therapies for Diverticular Disease of the Colon.  J Clin Gastroenterol., 42:1145-1151, 2008. 
  • Kiron M. Das, Immunologic basis for extraintestinal manifestations in inflammatory bowel disease UpToDate 2009
  • Pitchumoni, CS, Rubin, A, Das, KM.  Pancreatitis in inflammatory bowel diseases.  J Clin Gastroenterol,, Clinical Review 44:246-253, 2010.
  • Tejas Sheth, Capecomorin S. Pitchumoni, and Kiron M. Das.  J. Clin Gastroenterol, Clinical Review 2014.


Kiron Moy Das

Professor

 

  • : (732) 235-7784 Fax: (732) 235-7792

  • DEPARTMENTDept.of Medicine, Division of
    Gastroenterology & Hepatology
    Rutgers, Robert Wood Johnson Medical School & Robert Wood Johnson
  • COUNTRY USA