Publications

• *G. Abdel-Fattah, B. Watzl, D. Haung and R.R Watson. Beta Carotene in vitro stimulates interleukin 1 alpha and tumor necrosis factor alpha in human peripheral blood mononuclear cells. Nutr. Res.1993; 13:863-871. * Also known as Ghada A. Soliman
• Fernandez M. L., *G. Abdel-Fattah, and D. J. McNamara. Dietary fat saturation modifies the metabolism of LDL subfractions in guinea pigs. Arteriosclerosis and Thrombosis 1993; 13:1418-1428.
• *Abdel-Fattah G., M. L. Fernandez and D. J. McNamara. Regulation of hepatic very low-density lipoprotein secretion rates by dietary fat saturation in guinea pigs. J. Lipid Res. 1995; 36: 1418-1428.
• Fernandez M. L., *G. Abdel-Fattah, D. J. McNamara. Differential effects of simple versus complex carbohydrates on very low-density lipoproteins and high-density lipoproteins in the guinea pigs. Biophys. Biochem. Acta 1995; 1256: 31-38.
• Fernandez M.L., Vergara-Jimenez M, Conde K, and *G. Abdel-Fattah. Dietary carbohydrate type and fat amount alter VLDL and LDL metabolism in Guinea Pigs. J. Nutrition 1996; 126: 2494-2504.
• Fernandez M. L., M. Vergara-Jimenez, K. Konde, T. Behr, and *G. Abdel-Fattah. Regulation of VLDL-LDL apo B metabolism and plasma lipoprotein in Guinea Pigs by Dietary Soluble fiber. Am. J. Clinical Nutrition 1997; 65: 814-822.
• *Abdel-Fattah G., M. L. Fernandez, and D. J. McNamara. Regulation of Very Low Density Lipoprotein Apo B metabolism by dietary fat saturation and chain length in the guinea Pig. Lipids 1998; 33: 23-30.
• *Abdel-Fattah G., Yoffe B., Krishnan B, Khaoustov V, and Itani K. MDM2/p53 protein expression in the development of colorectal adenocarcinoma. J. Gastrointestinal Surg. 2000, Jan-Feb; 4(1): 109-114.
• Hadsell DL, and *Abdel-Fattah G. Regulation of cell apoptosis by insulin-like growth factor I. Advances in Experimental Medicine and Biology. 2001: 501: 79-85. * Also known as Ghada A. Soliman
• Morrisett JD, *Abdel-Fattah G., Hoogeveen R, Ballantyne CM, Pownall HJ, Opekun AR, Jaffe JS, Oppermann S, Kahan BD. Effects of Sirolimus (rapamycin) on plasma lipids and free fatty acids (FFA) in renal transplant patients. Journal of Lipid Research, 2002 Aug; 43(8):1170-80.
• Morrisett JD, *Abdel-Fattah G, Kahan BD. Invited participation, Continued Medical Education, University of Texas. Sirolimus changes lipid concentrations and lipoprotein metabolism in kidney transplant recipients. Transplant Proc. 2003 May; 35(3 Suppl): 143S-150S. * Also known as GhadaA. Soliman.
• Soliman GA. The mTOR signaling network and gene regulation. Current Opinion in Lipidology, 2005, June; 16:317-323.
• Aggarwal D, Fernandez ML, and Soliman GA. Rapamycin, an mTOR inhibitor, disrupts triglyceride metabolism in guinea pigs. Metabolism, 2006 Jun; 55(6):794-802.
• Aggarwal D, Hedley CF, Soliman GA, Dutta A, and Fernandez ML. Validation of gene expression in peripheral mononuclear cells as marker of hepatic cholesterol metabolism in guinea pigs. Lipids in Health and Disease, 2006 Aug 15; 5:22.
• GA Soliman, R Ishida-Takahashi, Y Gong, T Saunders, DC Fingar, and MG Myers, Jr. A simple qPCR-based method to detect correct insertion of homologous targeting vectors in embryonic stem cells. Transgenic Research 2007 Oct; 16(5):665-70.
• Acosta-Jaquez H, Keller J, Foster K, Ekim B, Soliman GA, Ballif BA, and Fingar DC. Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.Mol Cell Biol. 2009 Aug; 29(15):4308-24.
• Foster KG, Acosta-Jaquez HA, Romeo Y, Ekim B, Soliman GA, Carriere A, Roux PP, Ballif BA, Fingar DC. Regulation of mTOR complex 1 (mTORC1) by raptor S863 and multi-site. J Biol Chem. 2010 Jan 1; 285(1):80-94.
• Soliman GA, Acosta-Jaquez H, Dunlop EA, Ekim B, Maj NE, Tee AR, Fingar DC. mTOR S2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action. J Biol Chem. 2010 Mar 12; 285(11):7866-79.
• Soliman GA, Acosta-Jaquez H, and DC. Fingar. mTOR inhibition via rapamycin promotes triacylglycerol lipolysis and release free fatty acids in 3T3-L1 adipocytes, Lipids 2010, 45: 1089-100.
• Soliman GA. The Integral Role of mTOR in Lipid Metabolism. Cell Cycle. Volume 10, Issue 6: 861 – 862, 2011.
• Schiefelbein EL, Zekri A, Newton D, Soliman GA, Banerjee M, Hung C-W, Iyer P, Seifeldin IA, Ramadan M, Lo A, Soliman AS. Hepatitis C and other risk factors in hepatocellular carcinoma. Acta Virologica 2012; 56(3):235-40. 2012.
• Soliman GA. The Role of Mechanistic Target of Rapamycin (mTOR) Complexes Signaling in the Immune Responses, Nutrients, 2013: 5: 2231-2257.
• Soliman GA and Etekpo A. Effects of Metformin and ATP-competitive inhibitor of mTOR on targeted-metabolomic profile in HPAF-II Pancreatic Cancer Cell lines (manuscript in preparation).

Oral And Poster Presentations At Professional Meetings

• Federation Associations of the Society of Experimental Biology (FASEB 1991) Oral presentation: "In Vitro effects of Beta carotene on cytokines secretion in human peripheral mononuclear cells", Atlanta, Georgia.
• FASEB 1993 Oral presentation: "Dietary fat saturation effects on Very Low Density Lipoprotein secretion in the guinea pig" New Orleans, Louisiana.
• FASEB 1994 Poster presentation: "Differential effects of simple versus complex carbohydrates on Very Low Density Lipoproteins secretion rates and High Density Lipoproteins metabolism in guinea pigs", Washington, DC.
• FASEB 1995 Poster presentation: "Regulation of VLDL-LDL Apo B kinetics by dietary fat saturation and chain length in the Guinea Pigs", New Orleans, Louisiana.
• FASEB 1996 Poster presentation: "Dietary carbohydrate (CHO) type and amount interact to alter VLDL and LDL metabolism in the Guinea Pigs". Orlando, Florida.
• Endocrine Society Meeting (Endo) 1997 Poster presentation: "Specific binding of mammary nuclear proteins to putative insulin-responsive elements within the proximal mouse -casein promoter", Minneapolis, Minnesota.
• Experimental Biology (EB) 1998 Poster presentation: "Activity of Upstream Stimulatory Factor (USF) during mammary gland development and milk protein gene expression", San Francisco, California.
• American College of Surgeons (ACS) 1999 South Texas Chapter- Oral presentation: "MDM2/p53 protein expression in colon cancer" February 1999.
• Surgical Society of the Alimentary tract (SSAT) 1999 Poster presentation: “MDM2/p53 in the development of colorectal cancer”. Digestive Disease Week, May 1999.
• Atherosclerosis and Vascular Biology Seminar Series 2001: Oral presentation Baylor College of Medicine: “Signal Transduction pathways of Rapamycin in Hyperlipidemia” March 7, 2001.
• University of Texas Health Science Center, 2001. Division of Immunology and Organ Transplantation 24th Annual Retreat. Oral Presentation “Effect of Rapamycin on Blood Lipid Synthesis and Clearance”. April 26, 2001.
• Atherosclerosis and Vascular Biology Seminar Series, 2003: Oral presentation Baylor College of Medicine: “Signal Transduction of the mammalian Target of Rapamycin (mTOR)” January 23, 2003
• The Experimental Biology Meeting (EB-2004) *Abdel-Fattah G, Narayanan R. Knutson V, Morrisett J, Weigel NL. Insulin activation of mTOR is required for optimal insulin dependent triglyceride accumulation in 3T3-L1 Adipocytes. (FASEB J. A-877, April 2004 Abstract 585.3)
• The Experimental Biology Meeting (EB 2006) (April 2nd, 2006, poster) Aggarwal D, Fernandez ML, and GA Soliman. Mechanisms by which rapamycin induces hypertriglyceridemia in guinea pigs
• The Experimental Biology Meeting (EB-2006) (April 5th, 2006, poster).  Aggarwal D, Hedley CF, Soliman G, Dutta A, and Fernandez ML. Validation of Gene Expression In Monocytes As Marker of Hepatic LDL Receptor And HMG-CoA Reductase expression.
• Department of Internal Medicine Research Symposium. May 19-20, 2006. GA Soliman, Nancy Weigel, Victoria Knutson, and Diane C. Fingar. mTOR inhibits triglyceride lipolysis and promotes triglyceride accumulation in 3T3-L1 adipocytes.
• University of Michigan Department of Internal Medicine Research Symposium May 3-4 2007. Ghada A. Soliman, Ryoko Ishida-Takahashi, Yusong Gong, Thom Saunders, Diane C. Fingar, and Martin G. Myers, Jr. A simple qPCR-based method to detect correct insertion of homologous targeting vectors in embryonic stem cells.
• The Experimental Biology Meeting (EB-2008) (April 8th, 2008). Soliman G and Fingar DC. The role of mTORC1 signaling in -adrenergic–stimulated lipolysis and free fatty acid release in 3T3-L1 adipocytes.
• Guest Speaker: South West Michigan Dietetic Association. Obesity and Genetics. Kalamazoo MI, May 20, 2011.
• American Association of Cancer Research (AACR) Conference. Metabolism and Cancer. October 16-18, 2011.
• Metabolomics and Obesity Symposium. University of Michigan Metabolomics, Obesity and Nutrition Center, Ann Arbor, Michigan, October 19, 2011
• Weight Management Research and Applications for Practice: A Winning Pair, Weight Management Dietetic Practice Group (DPG) Symposium, March 2-4, 2012
• Invited Keynote Speaker, Michigan Dietetic Association (MDA) Annual Meeting: Management of Obesity from Genetics and Signal Transduction to Intervention and Follow -up. East Lansing, Michigan, April 26, 2012
• Metabolomics and Obesity Symposium. University of Michigan, Nutrition Obesity Research Center and Michigan Metabolomics and Obesity Center, Ann Arbor, Michigan, Scheduled October 16-17, 2012
• Experimental Biology (EB) 2013 Conference, Boston. Co-Chair Mini symposium Session: Eating Behavior and Behavioral Change, Scheduled April, 22 2013
• American Association of Cancer Research, (AACR): Pancreatic Cancer Research Treatment and Innovation held in New Orleans, LA, May 18-21, 2014 Poster Presentation. Effects of Metformin and ATP-competitive inhibitor of mTOR on targeted-metabolomic profile in HPAF-II Pancreatic Cancer Cell lines. Soliman GA and Etekpo A. University of Nebraska Medical Center, College of Public Health, Omaha, Nebraska 68198, AACR Programs and Proceedings, B53, 139, 2014