andrew-lobashevsky
Andrew Lobashevsky, PhD
Associate Professor of Medicine

Indiana University, School of Medicine
Indianapolis, USA
Phone: 317-948-8717
Email : alobashe@iu.edu

Education

Institution and Location DEGREE   Year Field of Study
Moscow Sechenov's Medical Academy M.D. 9/1975-6/1981 Medicine
Moscow Sechenov's Medical Academy. Russia Ph.D. 1/1982-2/ 1985 Medicine

Biography

Andrew Lobashevsky, MD, PhD, D(ABHI)- Diplomat of American Board of Histocompatibility and Immunogenetics is Associate Professor and Histocompatibility Laboratory Director at Department of Medicine of Indiana University and Clarian Health Partners Inc. He joined in the IU Department of Medicine in December 2004, as the Directory of the Immunology-Histocompatibility Laboratory. Previously, he was the Co-director of the HLA Laboratory at the University of Alabama at Birmingham Transplant Center, the third largest center in the country. He received his medical education and postgraduate training at the Department of Immunology and Microbiology of Sechenov’s Medical Academy, Moscow, Russia. He had his post-doctoral training in cellular and molecular immunology at the University of Tennessee at Memphis, and received transplant immunology/histocompatibility training at the University of Alabama at Birmingham. The laboratory headed by him is focused on providing service for the solid organ transplant programs as well as the bone marrow transplant activities of the Hematology/Oncology division at IU.


Research Interest

  1. IUPUI/MH –Role of permissible HLA mismatches in transplantation of high PRA renal candidates (2005 – present). Mechanisms of graft accommodation. Immunological mechanisms involved in development of different sensitivity to desensitization in sensitized renal transplant candidates. HLA allele mismatches and their effect on graft outcome in BM/SC recipients. Analysis of donor specific antibodies directed to public epitopes
  2. University of Alabama at Birmingham (1995-2005) - Mechanisms of tolerance in solid organ transplantation, veto effect, role of microchimerism. Polymorphism of cytokine genes in kidney recipients. Role of permissible HLA mismatches in high PRA renal candidates. Hematopoetic Stem cells engraftment monitoring. Clinical transplantation: post-transplant monitoring of kidney recipients.
  3. University of Tennessee (1991- 1995) - Biology of superantigenes, involvement of V and Vß regions of T cell receptors in allorecognition. Molecular mechanisms of allorecognition.
  4. Moscow Sechenov's Medical Academy (1982-1990) - Biology and functions of macrophages and polymorphonuclear leukocytes: locomotion, adhesion, phagocytosis and chemiluminiscence in Patients with opportunistic infections.

Scientific Activites

University Appointments

Dec. 2004- Present IUPUI at Indianapolis, Dept. of Medicine, Associate Professor
Sept. 1995- Dec. 2004 University of Alabama at Birmingham, Dept. of Surgery, Transplant Division; University of Tennessee Research Assistant Professor
Sept. 1991- June 1995
Dept. of Surgery, Transplant Division
Molecular Immunology of allorecognition
  Post-doctoral fellow
Sept.1989- Sept.1990 Dept. of Microbiology and Immunology Moscow Sechenov's Medical Academy Professor Assistant
Sept. 1984- Sept. 1989 Dept. of Microbiology and Immunology, Moscow Sechenov's Medical Academy Instructor

Other Appointments/Positions

Dec. 2004-Present IUPUI and Methodist Hospital, Transplant Immunology Laboratory Laboratory Director
Oct 2001- Dec 2004 University of Alabama at Birmingham Hospital, Tissue typing HLA lab Laboratory Co-Director
Jan. 1997-2001 University of Alabama at Birmingham Hospital, Tissue typing HLA lab. Laboratory Director assistant
Dec 1995-June 1997 Tissue typing HLA lab Laboratory Director in training
Sep 1990-Sep 1991 Institute of Biotechnology Laboratory of Immunoecology Senior researcher

Publications

Papers in Journals and Chapters in Books
  1. Lobashevsky AL et al., Rapid and strong de novo donor-specific antibody development in a lung transplant recipient. Transplant Immunology 2017, 40: 17-21.
  2. Mujtaba M, Hague J, Taber T, Lobashevsky A. et al., Effect of treatment with Tabalumab, a B-cell Activating Factor Inhibitor, on highly Sensitized patients with End Stage Renal Disease Awaiting Transplantation. Am. J. Transplant. 2016. V.30, p145-53.
  3. Kubal C., Mangus R., Saxena R., Lobashevsky A. et al., Prospective monitoring of Donor-specific anti-HLA Antibodies after Intestine/Multivisceral transplantation: Significance of de novo antibodies. Transplantation. 2015, 99(8), e49-56.
  4. Lobashevsky AL. Methodological aspects of anti-human leukocyte antigen antibody analysis in solid organ transplantation. World J Transplant 2014 September 24; 4(3): 153-215.
  5. Hommel-Berrey GA, House KD, Backfish KA, Arnoff TS, Lobashevsky AL. Identification of a novel HLA-DQB1 allele, DQB1*05:19, in an African American family by sequence-based typing. Tissue Antigens. 2013 Aug; 82(2):150-1.
  6. Kubal CA, Mangus RS, Vianna RM, Lobashevsky A, Mujtaba MA, Higgins N, Beduschi T,Fridell JA, Tector AJ. Impact of Positive Flow Cytometry Crossmatch on Outcomes of Intestinal/Multivisceral Transplantation: Role Anti-IL-2 Receptor Antibody. Transplantation. 2013, v.95(9), p.1160-6.
  7. Hommel-Berrey GA, House KD, Backfish KA, Arnoff TS, Lobashevsky AL. Identification of a novel HLA-DRB1 allele, DRB1*09:20, by sequence-based typing in an unrelated bone marrow donor. Tissue Antigens. 2013 Feb;81(2):125-6.
  8. TE Taber, MA Mujtaba, WC Goggins, N Higgins, AA Sharfuddin, MS Yaqub, DP Mishler, B Book, JM Chen, AL Lobashevsky. The effectiveness of the combination of rituximab and high-dose immunoglobulin in the immunomodulation of sensitized kidney transplant candidates. Clinical Transplantation. 2013, Vol.27, pp.EE375-382.
  9. AL Lobashevsky, et al., Analysis of anti-HLA antibodies in sensitized kidney transplant candidates subjected to desensitization with intravenous immunoglobulin (IVIG) and rituximab. Transplantation. 2013, v96 (2), p.182-190.
  10. A. Mujtaba, T. Taber, A. Lobashevskyet al., Early findings of Prospective Anti-HLA donor specific Antibodies Monitiring study in pancreas transplantation. Indiana University Health Experience. Clin Transplant. 2012 Sep-Oct;26(5):E492-9
  11. AL Lobashevsky.Chapter in the book “Characteristics, Detection, and Clinical Relevance of Alloantibodies in Kidney Transplantation”. Book Title “Kidney transplantation – New Perspectives”. ISBN 978-953-307-684-3. Edited by: Dr.(Md) Magdalena Trzcinska. Publisher: InTech, August 2011.
  12. MA Mujtaba, TE Taber, MS Yaqub, DP Mishler,ML Milgrom, JA Fridell, AL Lobashevsky et al., Early steroid withdrawal in repeat kidney transplantation. Clin J Am Soc Nephrol. 2011, 6(2): p.404-11.
  13. MA Mujtaba, W Goggins, AL Lobashevsky et al. The strength of donor-specific antibody is a more reliable predictor of antibody-mediated rejection than flow cytometry cross match analysis in desensitized kidney recipients. Clin Transplantation. 2011, 25(1), 96-102.
  14. AL Lobashevsky et al., Subtypes of immunoglobulin (Ig)-G antibodies against donor class II HLA and cross-match results in three kidney transplant candidates. Transplant Immunology, v.23, p.81-85. 2010.
  15. YA Serov, GA Hommel-Berrey and AL Lobashevsky. Identification of a novel HLA-Cw allele, Cw*021602, by sequence-based typing in a family of German decent. Tissue antigens. 2009.
  16. A Lobashevsky et al., Polymorphism of some cytokine genes correlates with susceptibility to desensitization. Transplant Immunology. v.21, p.169-178. 2009.
  17. YA Serov, GA Hommel-Berrey and AL Lobashevsky. Identification of novel HLA-DRB1*1165 allele. Tissue antigens. 2008.v71: p.489.
  18. YA Serov, GA Hommel-Berrey and AL Lobashevsky. Characterization of a new HLA-A*680202 allele identified by sequence-based typing. Tissue Antigens. 2009 Nov;74(5):435-7.
  19. AL Lobashevsky, RW Senkbeil, JE Townsend, CA Mink and JM Thomas. Quantitative analysis of chimerism and quality control of cell lineage short tandem repeat method (STR) using fluorescent automated DNA sequencer. Clinical and Laboratory Haematology 2006. v.28: p. 40-49
  20. Asiedu C., Dong S., Lobashevsky AL., Jenkins SM and Thomas JM.Tolerance induced by anti CD-3 immunotoxin plus 15-deoxyspergualin associates with donor-specific indirect pathway unresponsiveness.Cellular Immunology 223 (2003) 103-112.
  21. Kowalski R., Post D., Schneider MC., Britz J., Thomas JM., Deierhoi M., Lobashevsky AL., et al. Immune cell function testing: an adjunct to therapeutic drug monitoring in transplant patient management. Clinical Transplantation. 2003: v 17, p.77-88.
  22. Contreras J. L., Jenkins S, Eckhoff D. E., Hubbard W. J., Lobashevsky A. L. et al., Stable - and -Islet Cell Function After Tolerance Induction to Pancreatic Islet Allografts in Diabetic Primates. American Journal of Transplantation 2003. v 3: p 128-138.
  23. Lobashevsky AL, Asiedu C, Thomas JM. Absence of Microchimerism in kidney recipients long survivors rhesus macaques. HLA 2002. Congress Proceedings. 13 IHWC. P126.
  24. AL Lobashevsky, X. L. Jiang, J.M. Thomas. Allele-specific in situ analysis of microchimerism by fluorescence resonance energy transfer (fret) in non-human primate tissues. Human Immunology. 2002.v. 63. p. 108-120.
  25. AL Lobashevsky, RW Senkbeil, JL Shoaf,AK Stephenson, SB Skelton, RM Burke, MH Deierhoi and JM Thomas. The number of amino acid residues mismatches correlates with flow cytometry crossmatching results in high PRA renal patients. Human Immunology. 2002.v. 63, p.364-374.
  26. William J. Hubbard, Jill K. Moore, Juan L. Contreras, Cheryl A. Smith, Zeng W. Chen, Andrew L. Lobashevskyet al. Phenotypic and Functional analysis of T-cell recovery after anti-CD3 immunotoxin treatment for tolerance induction in Rhesus macaques. Human Immunology. 2001. v62. p.479-487.
  27. Thomas J, Contreras J, Cheryl A. Smith, Lobashevsky A.et al. Successful Reversal of Streptozocin-Induced Diabetes With Stable Allogenic islet Function in a Preclinical Model of Type 1 Diabetes. Diabetes. 2001. v50. p.1227-1236.
  28. Lobashevsky A., Senkbeil RW, Shoaf J, Mink C, Rowe C, Lobashevsky E, Burke R, Hudson S, Deierhoi M, Thomas J. Specificity of preformed alloantibodies causing B cell positive flow crossmatch in renal transplantation. Clinical transplantation. 2000. v14., p. 533-542.
  29. Lobashevsky A., Thomas J. Six Mamu-A Locus Alleles Defined by a Polymerase Chain Reaction Sequence Specific Primer Method. Human Immunology. 2000.v 61.,p. 1013-1020.
  30. Thomas J, Eckhoff D, Contreras J, Lobashevsky A. et al. Durable donor-specific T and B cell tolerance in Rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin. Transplantation. 2000. v.69. p. 2497-2503
  31. Lobashevsky AL, Smith J, Kasten-Jolly J, Horton H, Watkins D, Knapp L, Bontrop R, Thomas J. Identification of DRB alleles in Rhesus Monkeys using PCR-SSP amplification. Tissue Antigens. 1999. V54, p. 254-263
  32. Thomas J, Contreras J, Jiang X, Eckhoff D, Wang P, Hubbard W, Lobashevsky AL, et al. Immunologic mechanisms in peritransplant induction of stable allograft tolerance in a preclinical nonhuman primate model. Transplantation. 1999, v.68.,p.1660-1673
  33. Contreras J. L., Wang P. X., Eckhoff D. E., Lobashevsky A. L., Asiedu C., Frenette L., Robbin M.L., HubbardW. J., Cartner S., Nadler S., Cook W. J., Sharff J., Shiloach J., Thomas, F. T., Neville D. M., Thomas J. M. Peritransplant tolerance induction with anti-CD3-immunotoxin. Transplantation. 1998., v.65., p. 1159-1169.
  34. Lobashevsky A. L., et al., DR non-B1 mismatches influence allogeneic MLR-induced TH1- or TH2-like Cytokine responses in Rhesus Monkeys. Human Immunology., 1998.,v.59., p.363-372.
  35. Thomas J., Neville D., Contreras J. L., Eckhoff D., Meng G., Lobashevsky A., Wang P., Huang Z.,Verbanac K., Haish C., Thomas F. Preclinical Studies of allograft tolerance in Rhesus monkeys. A novel AntiCD3-Immunotoxin Given Peritransplant with Donor Bone Marrow Induces Operational Tolerance to kidney Allografts. Transplantation 1997, v. 64, p.124-135.
  36. Lobashevsky A. L., et al. Selective T cell receptor VB gene usage by alloreactive T cells responding to defined HLA-DR alleles. Transplantation., 1996,v62, p.1332-1340.
  37. Kotb M., Lobashevsky A.L., Guedes Y., Gaber O.,Evidence for VB restricted recognition of HLA-DR alleles. Transplantation Proceedings. 1997., v 29. p.1005-1007.
  38. Kotb M., Lobashevsky A.L., Guedez Y., Le Gros L., Henry J., Gaber O. Restricted Vß usage by alloreactive T cells responding to specific HLA DR alleles. Transplantation proceedings, 1995. V.27, pp.477-479.
  39. Hughes C.B., Henry J.,Kotb M, Lobashevsky A. L.,Sabek O., Gaber A.O. Up-regulation of TNF mRNA in the rat spleen following induction of acutepancreatitis. Journal of Surgical research.1995., v.59., 687-693.
  40. Lobashevsky A. L., Davydova N.V., Uriniuk V.M., Sukhareva N.N. The suppression of chemiluminiscence of mammalian cells by the metabolites of Crithidia oncopelti. Proceedings of National Academy of Science (Izvestia Academii Nauk), 1992., v.4., p.565-574.
  41. Lobashevsky A. L., Davydova N.V. Chemiluminiscence of human mono- and polymorphonuclear leukocytes, white blood cells and whole blood. Laboratory methods. (Laboratornoe delo). 1991, v.12, p.47.
  42. Lobashevsky A. L., Mannose-sensitive adhesins and hydrophobity of Gram-negative bacteria. The Journal of Microbiology, Epidemiology and Immunology (Zhurnal microbiologii, epidemiologii i immunologii). 1992, v3.p.68.          
  43. Lobashevsky A. L., Hydrophobity of Enterobacteria and Pseudomonads isolated from patients with pulmonary diseases. The Journal of Microbiology, Epidemiology and Immunology (Zhurnal microbio-logii, epidemiologii i immunologii).1992. v.10, p.24-26.
  44. Lobashevsky A. L., Mironov A. Yu.The effect of fatty acids from Bacteroids on phagocytosis of human neutrophils. The Journal of Microbiology, Epidemiology and Microbiology (Zhurnal microbiologii, epidemiologii i immunologii) 1991, v12. p.28.
  45. Dalina A.M., Lobashevsky A. L.,Dratvin S. A. Hemagglutinating properties of Entero-bacteria and Pseudomonads with mannose-sensitive pili and their ability to affect the activity of polymorphonuclear leukocytes. The Journal of Microbiology, Epidemiology and Immunology (Zhurnal microbiologii, epidemiologii i microbiologii). 1992. v.1., p.16.
  46. Lobashevsky A. L., Silin V.A., Popov P.Yu. The effect of antifungal agents on chemiluminiscence of polymorphonuclear leukocytes. The Journal of Microbiology, Epidemiology and Microbiology (Zhurnal micribiologii, epidemiologii i immunologii), 1989, v.10. p.46.
  47. Lobashevsky A. L., Kochemasova Z.N.Tumor necrosis factor. Antitumor activity of some bacteria and their components. (Review). Advances in modern Biology. (Uspekhi sovremennoi biologii) 1988.v.105.p.217-230.
  48. Lobashevsky A. L., Biochemical identification of Enterobacteria and Pseudomonads by using digital codes. Laboratory methods (Laboratornoe delo), 1987., v.2., p.16.
  49. Lobashevsky A. L. Migrational and adhesive activity of neutrophils from healthy donors under effect of Gram-negative bacteria. Pathology and experimental therapy. (Patologicheskaya phisiologiai experimentalnaya terapia). 1986. v.1., p.28.
  50. Lobashevsky A. L.,Dratvin S.A., Ovchinnikov A.A. The opportunity of fibrobronchoscopy usage in bacteriological examination of lower compartment of respiratory tract. Russian-Japan Meeting "Advances in Modern bronchoskopy". 1985. Moscow-Tokyo., p.55.
  51. Patent #1174855, Russia., Moscow. LobashevskyA.L., KochemasovaZ.N., Dratvin S.A. The mode of quantity determination of highly adhesivepolymorphonuclearleukocytes subset.
  52. Lobashevsky A. L., Dratvin S.A., Kochemasova Z. N. The mode of quantity determination of highly adhesive polymorphonuclear leukocytes subset. Hematology and Transfusiology(Gematologya i transfusiologya).1986. v.1., p.53.       
  53. Lobashevsky A. L., Capacity for changing the migrational and adhesive activity of polymorphonuclear leukocytes as one of the features of Gram-negative bacteria isolated from patients with purulent pulmonary lesions.The Journal of Microbiology, Epidemiology and Immunology (Zhurnal microbiologii, epidemiologii and immunologii). 1985.,v11.,p.46.
  54. Lobashevsky A. L.,Cnernyshov V.S., Kochemasova Z. N. Biological properties of Gram-negative bacteria isolated from patients with pyo-destructive pulmonary diseases. The Journal of Microbiology, Immunology and Epidemiology (Zhurnal mikrobiologii, epidemiologii i immunologii), 1985., v.6.,p.107.
  55. Lobashevsky A. L.,, Cnernyshov V.S., Marchenkova N.S. Migrational and adhesive activity of neutrophils in inflammatory and pyodestructive pulmonary diseases. Clinical Medicine (Klinicheskaya medicina),1985., v.5., p.69.
  56. Lobashevsky A. L., Dratvin S.A., Tashliev A.R. The opportunity of fibrobronchoskopy usage for bacterial examination of low compartments of respiratory tract. Laboratory methods (Laboratornoe delo),1984., v.3., p.173.
  57. Davydova N. V., Matveeva E.A., Kochemasova Z.N., Bagdasarov V.V., Lobashevsky A.L., Influence of low-frequency sonication on chemotactic and phagocytic activity of peritoneal rat macrophages.The Journal of Microbiology, Immunology and Epidemiology (Zhurnal mikrobiologii, epidemiologii i immunologii), 1984, v.5. p.56-60.
  58. Lobashevsky A. L., Kochemasova Z.N. On the time of Boyden type chambers incubation in estimating the quantity of neutrophils capable to taxis. Laboratory methods (Laboratornoe delo), 1983., v.7., p.55.
  59. Lobashevsky A. L., Kochemasova Z.N. Isolation of polymorphonuclear leukocytes from small volumes of blood after sedimentation with dextran. Laboratory methods. (Laboratornoe delo), 1983. v 11.,p.28.
  60. Lobashevsky A. L., Norkina E.S., Dratvin S.A. Chemokinesis of polymorphonuclear leukocytes through membranes of various types. Laboratory methods (Laboratornoe delo), 1983. v1. p.27.
Abstracts at Meetings
  1. A Lobashevsky A et al., Impact of minor HLA allelic mismatches on outcomes of hematopoietic cell transplants. ASHI annual meeting, St.Louis, MO. September 2016. Human Immunology 2016, P042.
  2. A Lobashevsky et al., Rapid de novo donor specific antibody development in lung transplant recipient. ASHI annual meeting, St.Louis, MO. September 2016. Human Immunology 2016, P134.
  3. A Lobashevsky et al., Eplet/epitope analysis of anti-HL antibodies can be used to determine positive MFI cut off of complement binding antibodies. ASHI annual meeting, Savanah, GA October 2015. Human Immunology 2015,
  4. A Lobashevsky, K Rosner. Weakly reactive non-self+self eplet pair specific antibodies produce positive flow cytometry cross match. EFI Annual meeting. Stockholm, Sweden, May 2014. Tissue antigens, 2014
  5. A Lobashevsky, K Rosner, M Kincade, N Higgins. B cell positive flowcytometry cross match due to donor specific antibodies of IgM isotype. ASHI Annual Meeting. Aspen, CO, October 2014, Human Immunology
  6. A Lobashevsky et al. Analysis of anti-HLA antibodies in sensitized kidney transplant candidates subjected to desensitization with intravenous immunoglobulin (IVIG) and rituximab. ASHI Annual Meeting. Chicago.November 2013 (oral presentation).
  7. William Goggins, Martin Milgrom, John Powelson, Jeanne Chen, Nancy Higgins, Daniel Smith, Andrew Lobashevsky, et al. Rapid Steroid Withdrawal in Desensitized Renal Transplant Recipient. ATC annual meeting. Seattle, WA. May 18-22, 2013
  8. A Lobashevsky et al., Elimination of non-specific reactivity of sera is a consideration in interpreting of solid phase antibody data. Abstracts at 16th IHIWS Liverpool, UK. 2012 Tissue antigens, V 79, (6), p. 499
  9. A Lobashevsky et al., MFI Predicitve values of anti-hla-c antibodies detected by single antigen beads (SAB) luminex solid phase method.Abstracts at 16th IHIWS Liverpool, UK. 2012 Tissue antigens, V 79, (6), p. 500
  10. A Lobashevsky et al.,Successful kidney transplantation against positive flow cytometry (fc) cross match (CM) cauzed by donor specific antibodies (DSA) without intensive immunomodulation. 36th ASHI Annual meeting. New Orleans, Louisiana. 2011
  11. A Lobashevsky et al., Do we really know everything about cross match (or does IgG subtype matter)? 35th ASHI Annual meeting. Miami, Florida. 2010
  12. S Farag, R Nelson, A Lobashevsky et al., Low CD4 T-Lymphocyte Reactivity by the Cylex ImmuKnow Assay Predicts Viral Infections Following Allogeneic Hematopoietic Stem Cell Transplantation. American Society for Hematology. 2009.
  13. A Lobashevsky et al., Comparative evaluation of Tepnel Lifecodes solid phase and lymphocyte cross match assays. May 2009. 22 European Foundation for Immunogenetics annual meeting. ULM, Germany.
  14. YA Serov, GA Hommel-Berrey and AL Lobashevsky. Identification of a novel HLA-Cw allele, Cw*021602, by sequence-based typing in a family of German decent. 2009 34th ASHI Annual meeting. San Francisco, California.
  15. AL Lobashevsky, N Higgins. MFI predicitive values of Class I and class II anti-HLA antibodies detected by LUMINEX. 2009 34th ASHI Annual meeting. San Francisco, California.
  16. T Taber, P Reddy, W Goggins, A Lobashevsky, N Higgins. Comparison of Renal transplant allograft function between a desensitized population vs. a high PRA non-desensitized population. American society of Nephrology Annual meeting. 2008
  17. AL Lobashevsky, YA Serov, GA Hommel-Berrey Identification of a novel HLA*A680202 allele by sequence-based typing in an african american individual. 2008 34th ASHI Annual meeting.
  18. A Lobashevsky, et al., Polymorphism of IL-12 and IFN genes correlates with susceptibility itivity to desensitization. 15 IHIWS. 2008. RioDejanejro, Brazil.
  19. A Lobashevsky, Y Serov, and G Hommel-Berrey. Identification of novel HLA-DRB1 allele by sequence-based typing in african-american population. 22 European Foundation for Immunogenetics annual meeting. 2008. Toulouse, France.
  20. A Lobashevsky, et al., Polymorphism of some cytokine genes correlates with susceptibility to desensitization. October 2007. 33rd ASHI annual meeting. Minneapolis, MN.
  21. A Lobashevsky, et al., Anti-HLA-I antibody profile in kidney transplant candidates correlates with HLA-DR epletype of the responder. 2nd International Congress on Immune Mediated Diseases. Moscow, Russia. September 10-15. 2007
  22. AL Lobashevsky et al., Analysis of HLA antibodies in transplant candidates with PRA more than ninety percent. European Foundation for Immunogenetics annual meeting. May 2007. Barcelona, Spain.
  23. YA Serov, AP Shah, BK Book, AC Tector and AL Lobashevsky. Quantitative analysis of     chimerism             using RT-PCR method. October 2006. 32nd ASHI annual meeting. San Diego,          CA.
  24. A.Lobashevsky, et al., Forteen day desensitization enabled kidney transplantation of patient with high pra and donor specific antibodies – a case study. October 2006. 32nd ASHI annual meeting. San Diego, CA.
  25. D Smith, A Lobashevsky et al., Is renal desensitization efficacious and evidence-based? ASFA 2006 Annual Meeting. Las Vegas, NE. #75.
  26. A Lobashevsky, et al., PCR-SSP method for identification of eight Mamu-B locus alleles.    20th EFI Conference. June 8-11, 2006. Oslo, Norway.
  27. AL Lobashevsky, et al., Solid organ transplant candidates demonstrate various sensitivity to IVIG treatment. Tissue typing laboratory, University of Indiana Hospital, Methodist Hospital. Indianapolis, IN.USA. October 2005. 31st ASHI annual meeting. p.114.Washington, DC.
  28. AL Lobashevsky, et al., Determination of permissible HLA class I mismatches in highly sensitized kidney recipients (or the continue of story of HLAMatchmaker algorithm). Tissue typing laboratory, University of Alabama Hospital, Birmingham.USA. 30th ASHI annual meeting. October 2004. S22. San-Antonio, TX.
  29. AL Lobashevsky, et al., Tissue typing laboratory, University of Alabama Hospital, Birmingham.USA Technical aspects of visible genetics sequencer application for short tandem repeat (STR) analysis. 29 ASHI Annual meeting. October 2003. S113. Miami, FL.
  30. AL Lobashevsky, et al., Unusual DRB1/DQB1 allelic association in renal transplant candidate. 28 ASHI Annual meeting. October 2002. S44. Nashville, TN.
  31. AL Lobashevsky, et al., PRA and alloantibody specificity analysis in renal patients using artificial substrate flow cytometry methods. 28 ASHI Annual meeting. October 2002. S65. Nashville, TN.
  32. AL Lobashevsky, et al., HLA-A, B, DR loci molecular typing using fluorescence PCR-SSO LUMINEX methodology. 28 ASHI Annual meeting. October 2002. S91. Nashville, TN.
  33. Contreras JL, Jenkins S, Eckhoff D, Lobashevsky A, Thomas F. Stable  and islet cell function after tolerance induction to pancreatic islet transplants in STZ-induced diabetic primates. American Transplant Congress. Washington, DC. April-May 2002. Abstract #26.P144.
  34. Sai SD, Asiedu C, Lobashevsky A, Jenkins S, Thomas JM. Stable tolerance induced by Anti-CD3 immunotoxin plus deoxyspergualin associates with suppression of anti-donor indirect pathway reactivity. American Transplant Congress. Washington, DC. April-May 2002. Abstract #29. P145
  35. Contreras JL, Smyth C, Eckhoff D, Lobashevsky A, Thomas F, Thomas JM. 15-DSG improves immediate functional islet mass (FIM) after pancreatic islet transplantation (PIT) in STZ-induced diabetic primates. AST/ASTS Annual Meeting. Chicago. May 2001. Abstract #934, p.371.
  36. Thomas JM, Contreras JL, Smyth C, Eckhoff D, Lobashevsky A, Thomas F. Long-term metabolic studies in STZ-induced primate recipient after tolerance induction to allogenic pancreatic islet transplants (PIT). AST/ASTS Annual Meeting. Chicago. May 2001. Abstract #32, p.143.
  37. Thomas JM, AL Lobashevsky, Smyth C, Hubbard W, Eckhoff D, Contreras JL, Neville D, Thomas F. STEALTH, the 3-d model of primate tolerance: evidence for sustained TH2 cytokine production in long term (LT) survivors. AST/ASTS Annual Meeting. Chicago. May 2001. Abstract #27, p.142.
  38. Rayburn BK, Kirklin JK, Brown RN, George JF, Thomas JM, Senkbeil RW, Lobashevsky AL, McGiffin DC, Bourge RC, Benza RL, Foley BA. The positive B-cell crossmatch: are all crossmatches created equal? 22nd Annual Meeting and Scientific Sessions. The international Society for Heart and Lung Transplantation. April 2002. Washington DC.
  39. Lobashevsky AL, et al, Molecular and cellular analysis of microchimerism in non-human primate kidney recipients. 11-th International Congress of Immunology. Stockholm. Sweden. July/August 2001. p.112.
  40. Contreras JL, Smyth C, Eckhoff D, Lobashevsky AL, Thomas FT, Thomas JM.15-DSG improves immediate functional islet mass after pancreatic islet transplantation in STZ-induced diabetic primates. Annual AST meeting. Chicago. May 2001. p 397.
  41. Thomas JM, Contreras JL, Smyth C, Eckhoff D, Lobashevsky AL, Thomas FT. Long term metabolic studies in STZ induced primate recipients after tolerance induction to allogenic pancreatic islet transplants. Annual AST meeting. Chicago. May 2001. p 143.
  42. Thomas JM, Lobashevsky AL, Smyth C, Hubbard BW, Eckhoff D, Contreras JL, NevilleD, Thomas FT. STEALTH, the 3-rd model of primate tolerance: evidence for sustained TH2 cytokine production in the long term (LT) survivors. Annual AST meeting. Chicago. May 2001. p 142.
  43. Lobashevsky AL, et al., The number of amino acid residues mismatches correlates with flow cytometry crossmatching results in high PRA renal patients. 27 ASHI Annual meeting. October 2001. S23. San Francisco, CA.
  44. Eckhoff D, Contreras JL, Lobashevsky AL., Hubbard BW. et al. Preclinical paradigm of tolerance without chronic allograft nephropathy (CAN). XVII International Congress of the Transplantation Society. August 27- September 1, 2000. Rome, Italy. P0107W.
  45. Lobashevsky AL., Thomas J. Six Mamu-A locus alleles defined by PCR-SSP method. 14-th Conference of The European Federation for Immunogenetics. April 2000., p. S104. France. Monpellier
  46. Lobashevsky AL., et al. Does sequence based typing always provide the high level of resolution? 26 ASHI Annual meeting. October 2000. S117. Lake Buena Vista, FL.
  47. Lobashevsky AL., et al., Origin of tumors in solid organ transplant patients identified by PCR-SSP base methodology. 26 ASHI Annual meeting. October 2000. S137. Lake Buena Vista, FL.
  48. Lobashevsky AL., et al., PRA analysis using the flow PRA specific test. 25 ASHI Annual meeting. New Orleans, Louisiana. October 1999. S119.
  49. Contreras JL., Eckhoff DE., Smyth CA., Hubbard WJ., Lobashevsky AL. et al. Long-term islet allograft survival in STZ-induced diabetic non-human primates treated with only peritransplant F(ab)2-immunotoxin and deoxyspergualin. 1st Joint Annual Meeting of the American Society of Transplant Surgeons and the American Society of Transplantation. May 2000. Chicago. p.S417.
  50. Eckhoff DE., Contreras JL., Lobashevsky AL. et al. A preclinical paradigm of tolerance without chronic allograft nephropathy following peritransplant T cell ablation with dendritiv cell maturration arrest. 1st Joint Annual Meeting of the American Society of Transplant Surgeons and the American Society of Transplantation. May 2000. Chicago. p.S147.
  51. Eckhoff DE., Contreras JL., Lobashevsky AL. et al. A preclinical paradigm of tolerance without chronic allograft nephropathy. XVIII International Congress of the Transplantation in the new millenium. Italy. Rome. August- September 2000. P0107W
  52. Lobashevsky A., et al., Solid phase microparticle method for humoral immune response monitoring for solid organ transplantation. Sixth Basic Sciences Symposium of the Transplantation Society. Stanford. California. August. 1999.
  53. Thomas JM., Lobashevsky AL. et al. Tolerance without demonstrable chimerism: an alternative paradigm. XVII World Congress of the Transplantation Society.Montreal. Canada. July 12-17. p.156.
  54. Lobashevsky A., et al.,. Role of DR non-B1 mismatches in alloresponse and microchimerism analysis in kidney transplantation using rhesus monkey model. 24-th Annual ASHI meeting. Vancouver, Canada. October 1998. #1.2
  55. Thomas J. M., Lobashevsky A., Contreras J., Eckhoff D., Wang P., Hubbard W., Thomas F. Specific tolerance without demonstrable chimerism: an alternative paradigm.ASTP. 17-th Annual Meeting. May 1998. Chicago, IL. p80.
  56. Eckhoff D., Wang P., Hubbard W., Contreras J., Lobashevsky A., Neville D. Early systemic immunologic factors associated with induction of long term renal allograft tolerance without maintenance immunosuppressive drugs. ASTP. 17-th Annual Meeting. May 1998. Chicago, IL. p159.
  57. Thomas J. M., Lobashevsky A., Contreras J., Eckhoff D., Wang P., Huang Z., Hubbard W., Thomas F., Neville D., Tolerance without demonstrable chimerism: an alternative paradigm. XVII World Congress on transplantation. Montreal, Canada. July, 1998.,p.156
  58. Thomas, J.M., Contreras J., Eckhoff D., Wang P., Asiedu C., Lobashevsky A., Huang, Z.,Q., Neville D., Frenette L.,Cartner S., Robbin M., Thomas F. Tolerance induced by peritransplant administration of anti-CD3-immunotoxin (ACD3-IT), methylprednisolone (MP) and deoxyspergualin (DSG) in a preclinical model of cadaveric kidney trnasplantation in rhesus monkeys.17-th ASTP Meeting. Chicago. May 1998.
  59. Contreras J., Wang P., Eckhoff D., Sharff J., Asiedu C., Nadler S.,Lobashevsky A., Frenette L., Cox J., Neville D., Thomas F.Inhibition of interleukin 12 induced interferon-g release by DSG. 17-th ASTP meeting. Chicago. May 1998.
  60. Contreras J., Wang P., Eckhoff D., Sharff J., Asiedu C., Nadler S.,Lobashevsky A., Frenette L., Cox J., Neville D., Thomas F. Dissociation of Interferon- and interleukin-12 production related to allograft acceptance in recipients given peritransplant anti-CD3 immunotoxin, DSG and methylprednizolon. ASTR Annual meeting, Chicago, May 1997.
  61. Eckhoff D., Contreras J.,Wang P., Huang Z., Lobashevsky A., Cox J., Cartner S., Neville D., Thomas F.Immunologic mechanisms favoring operational transplant tolerance induced by deoxyspergualin (DSG) and methylprednizolone (MP) in Rhesus monkeys given anti-CD3 immunotoxin. 5-th Basic Science Symposium of the Transplantation Society., Sept. 1997., Chautauqua, NY.
  62. Lobashevsky A., et al., DR non B1 mismatches influence allogenic MLR-induced Th1 or Th2-like cytokine responses in Rhesus monkeys. 5-th Basic Science Symposium of the Transplantation Society., Sept. 1997., Chautauqua, NY.
  63. Lobashevsky A., et al., DR non B1 mismatches influence allogenic MLR-induced Th1 or Th2-like cytokine responses in Rhesus monkeys. Oral presentation at 16-th Annual meeting of ASTP., May 1997., Chicago, IL., p.232.
  64. Guedez Y., Norrby-Teglund A, Lobashevsky A., Low D., McGeer A., Kotb M. HLA class II Alleles associated with invasive group A streptococcal infections. 23-d Annual ASHI Meeting. Oct. 1997, #26., Atlanta, GA.
  65. Thomas J., Haisch C., Eckhoff D., Lobashevsky A., Contreras J., Verbanac K., Carver M., Thomas F.Stable long-term (1-5 year) survival (LTS) of kidney transplants (Ktx) in a preclinical model (PM) without chronic immunosuppressive drugs or pretransplant treatment. 23-3 Annual Scientific Meeting of ASTS. Chicago, IL. 1997, p. A-329.
  66. Thomas J., Contreras J., Haish C., Eckhoff D., Verbanac K., Lobashevsky A., Thomas F. Long Term (1-5 Year) Survival and Tolerance (LTST) of Rhesus Kidney Transplants (KTx) Without Chronic Immunosuppression Drugs: Long Term Look At Specific Tolerance (DST) in a preclinical Model. Abstracts at 4-th International Conference on Tolerance Induction.1997.p15., Breckenridge, Colorado.
  67. Lobashevsky A. L., Thomas J. M. Quantitative analysis of microchimerism in kidney transplants. Abstracts at XXII Annual ASHI Meeting. San-Diego, CA. 1996.
  68. Thomas J. M., Meng G., Thomas F. T., Haisch C. E., Lobashevsky A. L., Eckhoff D., Diethelm A. G. A novel anti-CD3 immunotoxin (IT) with potential for tolerance induction. (Oral presentation) Abstracts at XVI International Congress of Transplantation Society. Barcelona, Spain, 1996.
  69. Kotb M., Lobashevsky A.L., Guedes Y., Gaber O., Evidence for VB restricted recognition of HLA-DR alleles. (Oral presentation) Abstracts at XVI International Congress of Transplantation Society. Barcelona, Spain, 1996.
  70. Lobashevsky A.L., et al., VB restricted specific recognition of HLA-DR molecules presented via the direct pathway of allorecognition. Abstracts at 21-st Annual ASHI Meeting, Oct.1995., Dallas,TX.
  71. Lobashevsky A. L., et al., Restricted Vß usage by alloreactive T cells responding to specific HLA DR alleles. XV-th World Congress of The Transplantation Society.Aug-Sep.1994., Kyoto, Japan.
  72. Lobashevsky A. L., et al., T-cell restriction in recognition of HLA-DR allo-antigenes. Abstracts for ASHI 20-th Annual Meeting 1994, Pittsburgh, PA.
  73. Lobashevsky A. L.,The functions of polymorphonuclear leukocytes from patients with pulmonary diseases. Abstracts at the 2-nd International Conference of Hospital Infection Society. UK. London. 1990. #0305.
  74. Lobashevsky A. L., et al., Influence of Gram-negative bacteria isolated from patients with purulent pulmonary diseases on migration of neutrophils. Abstracts at the meeting "Acute lung and pleura purulent diseases".Ibid. p.19.
  75. Lobashevsky A. L., Cheburankina T. Yu. Properties of Gram-negative bacteria isolated from patients with pyo-destructive pulmonary diseases. Abstracts at the Conference " The Problems of diagnosis and treatment in multiprofile clinic". 1987., Russia., Moscow.,p.91
  76. Lobashevsky A. L., Cheburankina T. Yu. Properties of Gram-negative bacteria isolated from patients with pyo-destructive pulmonary diseases. Abstracts at the Conference " The Problems of diagnosis and treatment in multiprofile clinic". 1987., Russia., Moscow.,p.91
  77. Lobashevsky A. L., et al., Influence of blastolysin on migration and adhesion of polymorphonuclear leukocytes. Reserved at All-Union Information Institute. 1984., #11.
  78. Lobashevsky A. L., Dalina A.M. Hemagglutination properties of Pseudomonas aeruginosa and its ability to cause the pyo-destructive processes in lungs. Abstracts at the meeting "Bacterial infections and immunity". 1984., p.49., Bulgaria. Warna.
  79. Lobashevsky A. L., Dalina A.M. Adhesive properties of Enterobacteria and Pseudomonads as a pathogenic factor of purulent pulmonary diseases. Abstracts at the meeting "Cellular and humoral immune factors in various physiological and pathological states". 1984.,v. 9., p.32. Chelyabinsk. Russia.
  80. Matveeva E. A., Davydova N.V., Lobashevsky A. L., Chernyshov V. S., Dratvin S. A., Kochemasova Z. N. The capacity of using phagocytosis ratios as a course test in patients with purulent pulmonary diseases. Abstracts at the meeting "Opportunistic infection in noninfectious clinic". St.Petersburg. 1983., P.59.
  81. Dratvin S.A.,Lobashevsky A. L., Method for assessment of neutrophil migration and adhesion. Abstracts at the meeting "Scientific problems of health". Moscow. 1982. p.28.
  82. Lobashevsky A. L., Dratvin S.A. The experience of microbiological investigation of lung aspirates species obtained with the help of fibrobronchoscope. Proceedings of Uzbek Research Institute of Tuberculosis. Tashkent. 1982. P.94.

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